Biochemical and structural studies of malate synthase from Mycobacterium tuberculosis

Journal of Biological Chemistry

Volumn 278, Issue 3, 2003, Pages 1735-1743

  Smith, Clare V ^a   Huang, Chih Chin ^a,d   Miczak, Andras ^c   Russell, David G ^b   Sacchettini, James C ^a   Höner zu Bentrup, Kerstin ^b,e  

^a TEXAS A AND M UNIVERSITY   (United States)

^b Cornell University ^*  (United States)

^c UNIVERSITY OF SZEGED   (Hungary)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^e TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CHEMICAL REACTIONS; ENZYMES; GENETIC ENGINEERING; ORGANIC ACIDS;

COENZYMES;

DISEASE CONTROL;

ACETIC ACID; ACETYL COENZYME A; BROMOPYRUVIC ACID; CARBON; GLYOXYLIC ACID; ISOCITRATE LYASE; MALATE SYNTHASE; OXALIC ACID; PHOSPHOENOLPYRUVATE; PYRUVIC ACID DERIVATIVE; UNCLASSIFIED DRUG; GLYOXYLIC ACID DERIVATIVE; PRIMER DNA;

ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL METABOLISM; CITRIC ACID CYCLE; CONTROLLED STUDY; ENZYME BINDING; ENZYME ISOLATION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME PURIFICATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENETIC CODE; GLCB GENE; MOLECULAR CLONING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PRIORITY JOURNAL; AMINO ACID SEQUENCE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; PROKARYOTA; UNCULTURED ACTINOMYCETE;

AMINO ACID SEQUENCE; BASE SEQUENCE; CATALYSIS; DNA PRIMERS; GLYOXYLATES; MALATE SYNTHASE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EID: 0037449771     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209248200     Document Type: Article

References (66)

1. Wayne, L. G. (1994) Eur. J. Clin. Microbiol. Infect. Dis. 13, 908-914
2. Gupta, U. D., and Katoch, V. M. (1997) Indian J. Lepr. 69, 385-393
3. McKinney, J. D., Höner zu Bentrup, K., Munoz-Elias, E. J., Miczak, A., Chen, B., Chan, W. T., Swenson, D., Sacchettini, J. C., Jacobs, W. R., Jr., and Russell, D. G. (2000) Nature 406, 735-738
4. Cioni, M., Pinzauti, G., and Vanni, P. (1981) Comp. Biochem. Physiol. B Biochem. Physiol. 70, 1-26
5. Kannan, K. B., Katoch, V. M., Bharadwaj, V. P., Sharma, V. D., Datta, A. K., and Shivannavar, C. T. (1985) Indian J. Lepr. 57, 542-548
6. Wayne, L. G., and Lin, K. Y. (1982) Infect. Immunol. 37, 1042-1049
7. Höner Zu Bentrup, K., Miczak, A., Swenson, D. L., and Russell, D. G. (1999) J. Bacteriol. 181, 7161-7167
8. Lorenz, M. C., and Fink, G. R. (2001) Nature 412, 83-86
9. Hong, P. C., Tsolis, R. M., and Ficht, T. A. (2000) Infect. Immunol. 68, 4102-4107
10. Kelly, B. G., Wall, D. M., Boland, C. A., and Meijer, W. G. (2002) Microbiology 148, 793-798
11. Vereecke, D., Cornelis, K., Temmerman, W., Jaziri, M., Van Montagu, M., Holsters, M., and Goethals, K. (2002) J. Bacteriol. 184, 1112-1120
12. Cole, S. T., Brosch, R., Parkhill, J., Garnier, T., Churcher, C., Harris, D., Gordon, S. V., Eiglmeier, K., Gas, S., Barry, C. E., III, Tekaia, F., Badcock, K., Basham, D., Brown, D., Chillingworth, T., Connor, R., Davies, R., Devlin, K., Feltwell, T., Gentles, S., Hamlin, N., Holroyd, S., Hornsby, T., Jagels, K., Barrell, B. G., et al. (1998) Nature 393, 537-544
13. Reinscheid, D. J., Eikmanns, B. J., and Sahm, H. (1994) Microbiology 140, 3099-3108
14. Molina, I., Pellicer, M. T., Badia, J., Aguilar, J., and Baldoma, L. (1994) Eur. J. Biochem. 224, 541-548
15. Vanderwinkel, E., and De Vlieghere, M. (1968) Eur. J. Biochem. 5, 81-90
16. Blattner, F. R., Plunkett, G., III, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., and Shao, Y. (1997) Science 277, 1453-1474
17. Parkhill, J., Wren, B. W., Thomson, N. R., Titball, R. W., Holden, M. T., Prentice, M. B., Sebaihia, M., James, K. D., Churcher, C., Mungall, K. L., Baker, S., Basham, D., Bentley, S. D., Brooks, K., Cerdeno-Tarraga, A. M., Chillingworth, T., Cronin, A., Davies, R. M., Davis, P., Dougan, G., Feltwell, T., Hamlin, N., Holroyd, S., Jagels, K., Karlyshev, A. V., Leather, S., Moule, S., Oyston, P. C., Quail, M., Rutherford, K., Simmonds, M., Skelton, J., Stevens, K., Whitehead, S., and Barrell, B. G. (2001) Nature 413, 523-527
18. Heidelberg, J. F., Eisen, J. A., Nelson, W. C., Clayton, R. A., Gwinn, M. L., Dodson, R. J., Haft, D. H., Hickey, E. K., Peterson, J. D., Umayam, L., Gill, S. R., Nelson, K. E., Read, T. D., Tettelin, H., Richardson, D., Ermolaeva, M. D., Vamathevan, J., Bass, S., Qin, H., Dragoi, I., Sellers, P., McDonald, L., Utterback, T., Fleishmann, R. D., Nierman, W. C., and White, O. (2000) Nature 406, 477-483
19. Parrish, N. M., Dick, J. D., and Bishai, W. R. (1998) Trends Microbiol. 6, 107-112
20. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
21. Segel, I. (1975) Enzyme Kinetics, Wiley Interscience, New York
22. Stover, C. K., de la Cruz, V. F., Fuerst, T. R., Burlein, J. E., Benson, L. A., Bennett, L. T., Bansal, G. P., Young, J. F., Lee, M. H., Hatfull, G. F., et al. (1991) Nature 351, 456-460
23. Russo-Marie, F., Roederer, M., Sager, B., Herzenberg, L. A., and Kaiser, D. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 8194-8198
24. Otwinowski, Z., and Minor, W. (1997) in Methods in Enzymology (Carter, C., and Sweet, R., eds) Vol. 276, pp. 307-326, Academic Press, New York
25. Otwinowski, Z., and Minor, W. (2001) in International Tables for Crystallography (Rossman, M. G., and Arnold, E., eds) Vol. F, Kluwer Academic Publishers, Dordrecht, The Netherlands
26. Terwilliger, T. C., and Berendzen, J. (1999) Acta Crystallogr. D Biol. Crystallogr. 55, 849-861
27. de La Fortelle, E., and Bricogne, G. (1997) in Methods in Enzymology (Carter, C., and Sweet, R., eds) Vol. 276, pp. 472-494, Academic Press, New York
28. Cowtan, K., and Main, P. (1996) Acta Crystallogr. Sect. D Biol. Crystallogr. 52, 43-48
29. Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. A 47, 110-119
30. Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. D Biol. Crystallogr. 54, 905-921
31. Laskowski, R., MacArthur, M., Moss, D., and Thornton, J. (1993) J. Appl. Crystallogr. 26, 283-291
32. Navaza, J. (1994) Acta Crystallogr. Sect. A 50, 157-163
33. CCP4 (1994)Acta Crystallgr. Sect. D Biol. Crystallogr. 50, 760-763
34. Cozzone, A. J. (1998) Annu. Rev. Microbiol. 52, 127-164
35. Wayne, L. G., and Sohaskey, C. D. (2001)Annu. Rev. Microbiol. 55, 139-163
36. Zollner, H. (1989) Handbook of Enzyme Inhibitors, VCH Verlagsgesellschaft, Weinheim, Basel, Cambridge, New York
37. Beeckmans, S., Khan, A. S., Kanarek, L., and Van Driessche, E. (1994) Biochem. J. 303, 413-421
38. Sundaram, T. K., Chell, R. M., and Wilkinson, A. E. (1980) Arch. Biochem. Biophys. 199, 515-525
39. Cook, J. R. (1970) J. Protozool. 17, 232-235
40. Hendrickson, W. A. (1991) Science 254, 51-58
41. Howard, B. R., Endrizzi, J. A., and Remington, S. J. (2000) Biochemistry 39, 3156-3168
42. Holm, L., and Sander, C. (1993) J. Mol. Biol. 233, 123-138
43. Gerlt, J. A. (2000) Nat. Struct. Biol. 7, 171-173
44. Wierenga, R. K. (2001) FEBS Lett. 492, 193-198
45. Copley, R. R., and Bork, P. (2000) J. Mol. Biol. 303, 627-641
46. Lo Conte, L., Ailey, B., Hubbard, T. J., Brenner, S. E., Murzin, A. G., and Chothia, C. (2000) Nucleic Acids Res. 28, 257-259
47. Lo Conte, L., Brenner, S. E., Hubbard, T. J., Chothia, C., and Murzin, A. G. (2002) Nucleic Acids Res. 30, 264-267
48. Engel, C., and Wierenga, R. (1996) Curr. Opin. Struct. Biol, 6, 790-797
49. Kim, J. J., Wang, M., and Paschke, R. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 7523-7527
50. Wolodko, W. T., Fraser, M. E., James, M. N., and Bridger, W. A. (1994) J. Biol. Chem. 269, 10883-10890
51. Engel, C. K., Mathieu, M., Zeelen, J. P., Hiltunen, J. K., and Wierenga, R. K. (1996) EMBO J. 15, 5135-5145
52. Remington, S., Wiegand, G., and Huber, R. (1982) J. Mol. Biol. 158, 111-152
53. Mancia, F., Smith, G. A., and Evans, P. R. (1999) Biochemistry 38, 7999-8005
54. Gerlt, J., Kozarich, J., Kenyon, G., and Gassman, P. (1991) J. Am. Chem. Soc. 113, 9667-9669
55. Huttner, S., Mecke, D., and Frohlich, K. U. (1997) Gene 188, 239-246
56. Wiegand, G., Remington, S., Deisenhofer, J., and Huber, R. (1984) J. Mol. Biol. 174, 205-219
57. Remington, S. J. (1992) Curr. Top. Cell. Regul. 33, 209-229
58. Karpusas, M., Branchaud, B., and Remington, S. J. (1990) Biochemistry 29, 2213-2219
59. Kurz, L. C., Nakra, T., Stein, R., Plungkhen, W., Riley, M., Hsu, F., and Drysdale, G. R. (1998) Biochemistry 37, 9724-9737
60. Alter, G. M., Casazza, J. P., Zhi, W., Nemeth, P., Srere, P. A., and Evans, C. T. (1990) Biochemistry 29, 7557-7563
61. Evans, C. T., Kurz, L. C., Remington, S. J., and Srere, P. A. (1996) Biochemistry 35, 10661-10672
62. Babbitt, P. C., Hasson, M. S., Wedekind, J. E., Palmer, D. R., Barrett, W. C., Reed, G. H., Rayment, I., Ringe, D., Kenyon, G. L., and Gerlt, J. A. (1996) Biochemistry 35, 16489-16501
63. Kuhnel, K., and Luisi, B. F. (2001) J. Mol. Biol. 313, 583-592 64. Wedekind, J. E., Reed, G. H., and Rayment, I. (1995) Biochemistry 34, 4325-4330
64. Wedekind, J. E., Reed, G. H., and Rayment, I. (1995) Biochemistry 34, 4325-4330
65. Sharma, V., Sharma, S., Höner zu Bentrup, K., McKinney, J. D., Russell, D. G., Jacobs, W. R., Jr., and Sacchettini, J. C. (2000) Nat. Struct. Biol. 7, 663-668
66. Christopher, J. (1999) SPOCK. The Structural Properties Observation and Calculation Kit Program Manual, The Center for Macromolecular Design, Texas A & M University, College Station, TX