The synthesis of bioactive indolocarbazoles related to K-252a

Organic and Biomolecular Chemistry

Volumn 3, Issue 16, 2005, Pages 2953-2975

  Moffat, David ^a,c   Nichols, Christopher J ^b   Riley, Dean A ^b   Simpkins, Nigel S ^b  

^a UCB PHARMA   (Belgium)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c Chroma Therapeutics Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME KINETICS; HYDROXYLATION; LITHIUM COMPOUNDS; NITROGEN COMPOUNDS; OXIDATION; SUBSTITUTION REACTIONS;

BIOLOGICAL ACTIVITY; CYCLOPENTENE; DIHYDROXYLATION; KINASE ENZYMES;

SYNTHESIS (CHEMICAL);

CARBAZOLE DERIVATIVE; CYCLOPENTANE DERIVATIVE; EPIDERMAL GROWTH FACTOR RECEPTOR; K 252; MAP KINASE ACTIVATED KINASE 2; MAP-KINASE-ACTIVATED KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE INHIBITOR; PROTEIN SERINE THREONINE KINASE;

ARTICLE; DRUG ANTAGONISM; SYNTHESIS;

CARBAZOLES; CYCLOPENTANES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 24144432924     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b506444a     Document Type: Article

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