Synthesis of 1,7-annulated indoles and their applications in the studies of cyclin dependent kinase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 12, 2004, Pages 3057-3061

  Zhu, Guoxin ^a   Conner, Scott E ^a   Zhou, Xun ^a   Chan, Ho Kit ^a   Shih, Chuan ^a   Engler, Thomas A ^a   Al Awar, Rima S ^a   Brooks, Harold B ^a   Watkins, Scott A ^a   Spencer, Charles D ^a   Schultz, Richard M ^a   Dempsey, Jack A ^a   Considine, Eileen L ^a   Patel, Bharvin R ^a   Ogg, Catherine A ^a   Vasudevan, Vasu ^a   Lytle, Michelle L ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

1,7 Annulated indole; Cancer; D1 CDK4 inhibitor

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLIN DEPENDENT KINASE INHIBITOR; INDOLE DERIVATIVE; RETINOBLASTOMA PROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GROWTH; CARCINOMA CELL; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG SYNTHESIS; GROWTH INHIBITION; HUMAN; HUMAN CELL; PROTEIN PHOSPHORYLATION; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASES; GROWTH INHIBITORS; HUMANS; INDOLES; PROTEIN KINASE INHIBITORS;

EID: 2442417541     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.04.033     Document Type: Article

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