SCOPUS 정보 검색 플랫폼

Volumn 41, Issue 32, 2002, Pages 10304-10314

Toward a PKB inhibitor: Modification of a selective PKA inhibitor by rational design

(9) Reuveni, Hadas a Livnah, Nurit b Geiger, Tamar a Klein, Shoshana a Ohne, Osnat b Cohen, Ilana b Benhar, Moran a Gellerman, Gary b Levitzki, Alexander a

a HEBREW UNIVERSITY OF JERUSALEM (Israel)

b Peptor Ltd (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

RATIONAL DESIGN;

BIOASSAY; CELLS; LEAD COMPOUNDS; PROTEINS; TUMORS;

BIOCHEMISTRY;

AKSTATIN; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NL 71 101; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL LINE; COMBINATORIAL LIBRARY; CONTROLLED STUDY; DRUG DESIGN; DRUG EFFECT; DRUG EFFICACY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RADIOACTIVITY; REACTION ANALYSIS; STRUCTURE ANALYSIS; TUMOR CELL;

3T3 CELLS; ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; BINDING, COMPETITIVE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL LINE; COMBINATORIAL CHEMISTRY TECHNIQUES; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME INHIBITORS; GLYCOGEN SYNTHASE KINASE 3; HUMANS; ISOQUINOLINES; MICE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SULFONAMIDES; TUMOR CELLS, CULTURED;

EID: 0037072302 PISSN: 00062960 EISSN: None Source Type: Journal
DOI: 10.1021/bi0202530 Document Type: Article

Times cited : (115)

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