메뉴 건너뛰기




Volumn 6, Issue 4, 2004, Pages 521-523

Ruthenium Complexes as Protein Kinase Inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

BIPYRIDINE DERIVATIVE; CARBAZOLE DERIVATIVE; CARBOXYL GROUP; INDOLOCARBAZOLE; METHYL GROUP; PROTEIN KINASE INHIBITOR; RUTHENIUM COMPLEX; STAUROSPORINE; UNCLASSIFIED DRUG;

EID: 1342311501     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol036283s     Document Type: Article
Times cited : (66)

References (26)
  • 1
    • 0001381567 scopus 로고    scopus 로고
    • Metal-based drugs: (a) Orvig, C.; Abrams, M. J. Chem. Rev. 1999, 99, 2201-2842. (b) Guo, Z.; Sadler, P. J. Angew. Chem., Int. Ed. 1999, 38, 1512-1531.
    • (1999) Chem. Rev. , vol.99 , pp. 2201-2842
    • Orvig, C.1    Abrams, M.J.2
  • 2
    • 0001384447 scopus 로고    scopus 로고
    • Metal-based drugs: (a) Orvig, C.; Abrams, M. J. Chem. Rev. 1999, 99, 2201-2842. (b) Guo, Z.; Sadler, P. J. Angew. Chem., Int. Ed. 1999, 38, 1512-1531.
    • (1999) Angew. Chem., Int. Ed. , vol.38 , pp. 1512-1531
    • Guo, Z.1    Sadler, P.J.2
  • 4
    • 0033363495 scopus 로고    scopus 로고
    • Metal ions and metal complexes as enzyme inhibitors: Louie, A. Y.; Meade, T. J. Chem. Rev. 1999, 99, 2711-2734.
    • (1999) Chem. Rev. , vol.99 , pp. 2711-2734
    • Louie, A.Y.1    Meade, T.J.2
  • 10
    • 0034614490 scopus 로고    scopus 로고
    • Role of protein kinases in disease: (a) Hunter, T. Cell 2000, 100, 113-127. (b) Blume-Jensen, P.; Hunter, T. Nature 2001, 411, 355-365.
    • (2000) Cell , vol.100 , pp. 113-127
    • Hunter, T.1
  • 11
    • 0035902180 scopus 로고    scopus 로고
    • Role of protein kinases in disease: (a) Hunter, T. Cell 2000, 100, 113-127. (b) Blume-Jensen, P.; Hunter, T. Nature 2001, 411, 355-365.
    • (2001) Nature , vol.411 , pp. 355-365
    • Blume-Jensen, P.1    Hunter, T.2
  • 12
    • 0011672458 scopus 로고    scopus 로고
    • Protein kinase inhibitors: (a) García-Echeverría, C.; Traxler, P.; Evans, D. B. Med. Res. Rev. 2000, 20, 28-57. (b) Cohen, P. Nature Rev. Drug Discov. 2002, 1, 309-315. (c) Cole, P. A.; Courtney, A. D.; Shen, K.; Zhang, Z.; Qiao, Y.; Lu, W.; Williams, D. M. Acc. Chem. Res. 2003, 36, 444-452.
    • (2000) Med. Res. Rev. , vol.20 , pp. 28-57
    • García-Echeverría, C.1    Traxler, P.2    Evans, D.B.3
  • 13
    • 0036527429 scopus 로고    scopus 로고
    • Protein kinase inhibitors: (a) García-Echeverría, C.; Traxler, P.; Evans, D. B. Med. Res. Rev. 2000, 20, 28-57. (b) Cohen, P. Nature Rev. Drug Discov. 2002, 1, 309-315. (c) Cole, P. A.; Courtney, A. D.; Shen, K.; Zhang, Z.; Qiao, Y.; Lu, W.; Williams, D. M. Acc. Chem. Res. 2003, 36, 444-452.
    • (2002) Nature Rev. Drug Discov. , vol.1 , pp. 309-315
    • Cohen, P.1
  • 14
    • 0038679426 scopus 로고    scopus 로고
    • Protein kinase inhibitors: (a) García-Echeverría, C.; Traxler, P.; Evans, D. B. Med. Res. Rev. 2000, 20, 28-57. (b) Cohen, P. Nature Rev. Drug Discov. 2002, 1, 309-315. (c) Cole, P. A.; Courtney, A. D.; Shen, K.; Zhang, Z.; Qiao, Y.; Lu, W.; Williams, D. M. Acc. Chem. Res. 2003, 36, 444-452.
    • (2003) Acc. Chem. Res. , vol.36 , pp. 444-452
    • Cole, P.A.1    Courtney, A.D.2    Shen, K.3    Zhang, Z.4    Qiao, Y.5    Lu, W.6    Williams, D.M.7
  • 16
    • 0034646370 scopus 로고    scopus 로고
    • See also: (a) Gray, N. S.; Wodicka, L.; Thunnissen, A.-M. W. H.; Norman, T. C.; Kwon, S.; Hernan Espinoza, F.; Morgan, D. O.; Barnes, G.; LeClerc, S.; Meijer, L.; Kim, S.-H.; Lockhart, D. J.; Schultz, P. G. Science 2000, 281, 533-538. (b) Maly, D. J.; Choong, I. C.; Ellman, J. A. Proc. Natl. Acad. Sci 2000, 97, 2419-2424. (c) Bishop, A. C.; Buzko, O.; Shokat, K. M. Trends Cell Biol. 2001, 11, 167-172.
    • (2000) Proc. Natl. Acad. Sci , vol.97 , pp. 2419-2424
    • Maly, D.J.1    Choong, I.C.2    Ellman, J.A.3
  • 17
    • 0035312350 scopus 로고    scopus 로고
    • See also: (a) Gray, N. S.; Wodicka, L.; Thunnissen, A.-M. W. H.; Norman, T. C.; Kwon, S.; Hernan Espinoza, F.; Morgan, D. O.; Barnes, G.; LeClerc, S.; Meijer, L.; Kim, S.-H.; Lockhart, D. J.; Schultz, P. G. Science 2000, 281, 533-538. (b) Maly, D. J.; Choong, I. C.; Ellman, J. A. Proc. Natl. Acad. Sci 2000, 97, 2419-2424. (c) Bishop, A. C.; Buzko, O.; Shokat, K. M. Trends Cell Biol. 2001, 11, 167-172.
    • (2001) Trends Cell Biol. , vol.11 , pp. 167-172
    • Bishop, A.C.1    Buzko, O.2    Shokat, K.M.3
  • 23
    • 1342285709 scopus 로고    scopus 로고
    • note
    • Stability of ruthenium complexes with 3 and 4 is coupled to the electronic nature of the other ligands. Ligand 3 seems to prefer an electron-rich center, whereas 4 prefers a more electron-poor ruthenium center.
  • 24
    • 0024364398 scopus 로고
    • Noncompetitive inhibition of PKC with respect to ATP has been reported for adriamycin-Fe(III) and anthracycline-Cu(II) complexes: (a) Hannun, Y. A.; Foglesong, R. J.; Bell, R. M. J. Biol. Chem. 1989, 264, 9960-9966. (b) Monti, E.; Monzini, F.; Morazzoni, F.; Perletti, G.; Piccinini, F. Inorg. Chim. Acta 1993, 205, 181-184.
    • (1989) J. Biol. Chem. , vol.264 , pp. 9960-9966
    • Hannun, Y.A.1    Foglesong, R.J.2    Bell, R.M.3
  • 25
    • 0142146031 scopus 로고
    • Noncompetitive inhibition of PKC with respect to ATP has been reported for adriamycin-Fe(III) and anthracycline-Cu(II) complexes: (a) Hannun, Y. A.; Foglesong, R. J.; Bell, R. M. J. Biol. Chem. 1989, 264, 9960-9966. (b) Monti, E.; Monzini, F.; Morazzoni, F.; Perletti, G.; Piccinini, F. Inorg. Chim. Acta 1993, 205, 181-184.
    • (1993) Inorg. Chim. Acta , vol.205 , pp. 181-184
    • Monti, E.1    Monzini, F.2    Morazzoni, F.3    Perletti, G.4    Piccinini, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.