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Volumn 26, Issue 4-5 SPEC. ISS., 2005, Pages 391-404

Zinc prevention and treatment of alcoholic liver disease

Author keywords

Alcohol dehydrogenase; Apoptosis; CYP2E1; Endotoxemia; Glutathione; Metallothionein; TNF

Indexed keywords

ACETYLCYSTEINE; ALCOHOL; ALCOHOL DEHYDROGENASE; ANTIOXIDANT; CYTOCHROME P450 2E1; DIMETHYL SULFOXIDE; ENDOTOXIN; FAS LIGAND; METALLOTHIONEIN; TUMOR NECROSIS FACTOR ALPHA; ZINC;

EID: 24044547078     PISSN: 00982997     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mam.2005.07.002     Document Type: Review
Times cited : (102)

References (63)
  • 2
    • 0030045690 scopus 로고    scopus 로고
    • Role of cytochrome P4502E1-dependent formation of hydroxyethyl free radical in the development of liver damage in rats intragastrically fed with ethanol
    • E. Albano, P. Clot, M. Morimoto, A. Tomasi, M. Ingelman-Sundberg, and S.W. French Role of cytochrome P4502E1-dependent formation of hydroxyethyl free radical in the development of liver damage in rats intragastrically fed with ethanol Hepatology 23 1996 155 163
    • (1996) Hepatology , vol.23 , pp. 155-163
    • Albano, E.1    Clot, P.2    Morimoto, M.3    Tomasi, A.4    Ingelman-Sundberg, M.5    French, S.W.6
  • 4
    • 0036282179 scopus 로고    scopus 로고
    • Redox control of zinc finger proteins
    • M.A. Baldwin, and C.C. Benz Redox control of zinc finger proteins Methods Enzymol. 353 2002 54 69
    • (2002) Methods Enzymol. , vol.353 , pp. 54-69
    • Baldwin, M.A.1    Benz, C.C.2
  • 5
    • 0024211285 scopus 로고
    • Hepatic zinc content in patients with various stages of alcoholic liver disease and in patients with chronic active and chronic persistent hepatitis
    • J.C. Bode, P. Hanisch, H. Henning, W. Koenig, F.W. Richter, and C. Bode Hepatic zinc content in patients with various stages of alcoholic liver disease and in patients with chronic active and chronic persistent hepatitis Hepatology 8 1988 1605 1609
    • (1988) Hepatology , vol.8 , pp. 1605-1609
    • Bode, J.C.1    Hanisch, P.2    Henning, H.3    Koenig, W.4    Richter, F.W.5    Bode, C.6
  • 7
    • 0030006123 scopus 로고    scopus 로고
    • Reversible zinc exchange between metallothionein and the estrogen receptor zinc finger
    • D.F. Cano-Gauci, and B. Sarkar Reversible zinc exchange between metallothionein and the estrogen receptor zinc finger FEBS Lett. 386 1996 1 4
    • (1996) FEBS Lett. , vol.386 , pp. 1-4
    • Cano-Gauci, D.F.1    Sarkar, B.2
  • 8
    • 0029868268 scopus 로고    scopus 로고
    • Development and characterization of a binge drinking model in mice for evaluation of the immunological effects of ethanol
    • E.J. Carson, and S.B. Pruett Development and characterization of a binge drinking model in mice for evaluation of the immunological effects of ethanol Alcohol Clin. Exp. Res. 20 1996 132 138
    • (1996) Alcohol Clin. Exp. Res. , vol.20 , pp. 132-138
    • Carson, E.J.1    Pruett, S.B.2
  • 9
    • 0021191262 scopus 로고
    • Effects of zinc deficiency on ethanol metabolism and alcohol and aldehyde dehydrogenase activities
    • I. Das, R.E. Burch, and H.K. Hahn Effects of zinc deficiency on ethanol metabolism and alcohol and aldehyde dehydrogenase activities J. Lab. Clin. Med. 104 1984 610 617
    • (1984) J. Lab. Clin. Med. , vol.104 , pp. 610-617
    • Das, I.1    Burch, R.E.2    Hahn, H.K.3
  • 12
    • 0034859507 scopus 로고    scopus 로고
    • Zinc binding and redox control of p53 structure and function
    • P. Hainaut, and K. Mann Zinc binding and redox control of p53 structure and function Antioxid. Redox Signal. 3 2001 611 623
    • (2001) Antioxid. Redox Signal. , vol.3 , pp. 611-623
    • Hainaut, P.1    Mann, K.2
  • 13
    • 0027512980 scopus 로고
    • Purification and characterization of metallothionein and its activation of pyridoxal phosphokinase in trout (Salmo gairdneri) brain
    • R. Hao, R.F. Pfeiffer, and M. Ebadi Purification and characterization of metallothionein and its activation of pyridoxal phosphokinase in trout (Salmo gairdneri) brain Comp. Biochem. Physiol. B 104 1993 293 298
    • (1993) Comp. Biochem. Physiol. B , vol.104 , pp. 293-298
    • Hao, R.1    Pfeiffer, R.F.2    Ebadi, M.3
  • 14
    • 0035814762 scopus 로고    scopus 로고
    • Stoichiometry in zinc ion transfer from metallothionein to zinc finger peptides
    • Y. Hathout, D. Fabris, and C. Fenselau Stoichiometry in zinc ion transfer from metallothionein to zinc finger peptides Int. J. Mass Spectrom. 204 2001 1 6
    • (2001) Int. J. Mass Spectrom. , vol.204 , pp. 1-6
    • Hathout, Y.1    Fabris, D.2    Fenselau, C.3
  • 15
    • 0036083422 scopus 로고    scopus 로고
    • Alcohol and mitochondria: A dysfunctional relationship
    • J.B. Hoek, A. Cahill, and J.G. Pastorino Alcohol and mitochondria: a dysfunctional relationship Gastroenterology 122 2002 2049 2063
    • (2002) Gastroenterology , vol.122 , pp. 2049-2063
    • Hoek, J.B.1    Cahill, A.2    Pastorino, J.G.3
  • 16
    • 10344245018 scopus 로고    scopus 로고
    • Metallothionein gene therapy for chemical-induced liver fibrosis in mice
    • Y. Jiang, and Y.J. Kang Metallothionein gene therapy for chemical-induced liver fibrosis in mice Mol. Ther. 10 2004 1130 1139
    • (2004) Mol. Ther. , vol.10 , pp. 1130-1139
    • Jiang, Y.1    Kang, Y.J.2
  • 17
    • 0030774460 scopus 로고    scopus 로고
    • Frequency and distribution of DNA fragmentation as a marker of cell death in chronic liver diseases
    • Z. Jiang, Y. Liu, L. Savas, L. Smith, H. Bonkovsky, S. Baker, and B. Banner Frequency and distribution of DNA fragmentation as a marker of cell death in chronic liver diseases Virchows Arch. 431 1997 189 194
    • (1997) Virchows Arch. , vol.431 , pp. 189-194
    • Jiang, Z.1    Liu, Y.2    Savas, L.3    Smith, L.4    Bonkovsky, H.5    Baker, S.6    Banner, B.7
  • 18
    • 0141494281 scopus 로고    scopus 로고
    • CYP2E1: Biochemistry, toxicology, regulation and function in ethanol-induced liver injury
    • I. Kessova, and A.I. Cederbaum CYP2E1: biochemistry, toxicology, regulation and function in ethanol-induced liver injury Curr. Mol. Med. 3 2003 509 518
    • (2003) Curr. Mol. Med. , vol.3 , pp. 509-518
    • Kessova, I.1    Cederbaum, A.I.2
  • 21
    • 0034859653 scopus 로고    scopus 로고
    • Zinc finger proteins as molecular targets for nitric oxide-mediated gene regulation
    • K.D. Kroncke Zinc finger proteins as molecular targets for nitric oxide-mediated gene regulation Antioxid. Redox Signal. 3 2001 565 575
    • (2001) Antioxid. Redox Signal. , vol.3 , pp. 565-575
    • Kroncke, K.D.1
  • 22
    • 0038323922 scopus 로고    scopus 로고
    • Suppression of Fas-mediated signaling pathway is involved in zinc inhibition of ethanol-induced liver apoptosis
    • J.C. Lambert, Z. Zhou, and Y.J. Kang Suppression of Fas-mediated signaling pathway is involved in zinc inhibition of ethanol-induced liver apoptosis Exp. Biol. Med. (Maywood) 228 2003 406 412
    • (2003) Exp. Biol. Med. (Maywood) , vol.228 , pp. 406-412
    • Lambert, J.C.1    Zhou, Z.2    Kang, Y.J.3
  • 23
    • 0038814267 scopus 로고    scopus 로고
    • Prevention of alterations in intestinal permeability is involved in zinc inhibition of acute ethanol-induced liver damage in mice
    • J.C. Lambert, Z. Zhou, L. Wang, Z. Song, C.J. McClain, and Y.J. Kang Prevention of alterations in intestinal permeability is involved in zinc inhibition of acute ethanol-induced liver damage in mice J. Pharmacol. Exp. Ther. 305 2003 880 886
    • (2003) J. Pharmacol. Exp. Ther. , vol.305 , pp. 880-886
    • Lambert, J.C.1    Zhou, Z.2    Wang, L.3    Song, Z.4    McClain, C.J.5    Kang, Y.J.6
  • 24
    • 2442703070 scopus 로고    scopus 로고
    • Preservation of intestinal structural integrity by zinc is independent of metallothionein in alcohol-intoxicated mice
    • J.C. Lambert, Z. Zhou, L. Wang, Z. Song, C.J. McClain, and Y.J. Kang Preservation of intestinal structural integrity by zinc is independent of metallothionein in alcohol-intoxicated mice Am. J. Pathol. 164 2004 1959 1966
    • (2004) Am. J. Pathol. , vol.164 , pp. 1959-1966
    • Lambert, J.C.1    Zhou, Z.2    Wang, L.3    Song, Z.4    McClain, C.J.5    Kang, Y.J.6
  • 25
    • 0019085620 scopus 로고
    • Ligand substitution reactions of metallothioneins with EDTA and apo-carbonic anhydrase
    • T.Y. Li, A.J. Kraker, C.F. Shaw 3rd, and D.H. Petering Ligand substitution reactions of metallothioneins with EDTA and apo-carbonic anhydrase Proc. Natl. Acad. Sci. USA 77 1980 6334 6338
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 6334-6338
    • Li, T.Y.1    Kraker, A.J.2    Shaw III, C.F.3    Petering, D.H.4
  • 26
    • 0031035695 scopus 로고    scopus 로고
    • Ethanol metabolism, cirrhosis and alcoholism
    • C.S. Lieber Ethanol metabolism, cirrhosis and alcoholism Clin. Chim. Acta 257 1997 59 84
    • (1997) Clin. Chim. Acta , vol.257 , pp. 59-84
    • Lieber, C.S.1
  • 27
    • 0036024249 scopus 로고    scopus 로고
    • S-Adenosyl-l-methionine and alcoholic liver disease in animal models: Implications for early intervention in human beings
    • C.S. Lieber S-Adenosyl-l-methionine and alcoholic liver disease in animal models: implications for early intervention in human beings Alcohol 27 2002 173 177
    • (2002) Alcohol , vol.27 , pp. 173-177
    • Lieber, C.S.1
  • 28
    • 0025066673 scopus 로고
    • Alcohol intoxication, injuries, and dangerous behaviors-and the revolving emergency department door
    • S.R. Lowenstein, M.P. Weissberg, and D. Terry Alcohol intoxication, injuries, and dangerous behaviors-and the revolving emergency department door J. Trauma 30 1990 1252 1258
    • (1990) J. Trauma , vol.30 , pp. 1252-1258
    • Lowenstein, S.R.1    Weissberg, M.P.2    Terry, D.3
  • 29
    • 1642389890 scopus 로고    scopus 로고
    • Zinc and sulfur: A critical biological partnership
    • W. Maret Zinc and sulfur: a critical biological partnership Biochemistry 43 2004 3301 3309
    • (2004) Biochemistry , vol.43 , pp. 3301-3309
    • Maret, W.1
  • 33
    • 0038721028 scopus 로고
    • Alcohol dehydrogenase activity and previous ethanol consumption in mice
    • G.E. McClearn, E.L. Bennett, M. Hebert, R. Kakihana, and K. Schlesinger Alcohol dehydrogenase activity and previous ethanol consumption in mice Nature 203 1964 793 794
    • (1964) Nature , vol.203 , pp. 793-794
    • McClearn, G.E.1    Bennett, E.L.2    Hebert, M.3    Kakihana, R.4    Schlesinger, K.5
  • 34
    • 0036298103 scopus 로고    scopus 로고
    • Production of a cytochrome P450 2E1 transgenic mouse and initial evaluation of alcoholic liver damage
    • K. Morgan, S.W. French, and T.R. Morgan Production of a cytochrome P450 2E1 transgenic mouse and initial evaluation of alcoholic liver damage Hepatology 36 2002 122 134
    • (2002) Hepatology , vol.36 , pp. 122-134
    • Morgan, K.1    French, S.W.2    Morgan, T.R.3
  • 37
    • 0034653559 scopus 로고    scopus 로고
    • Apoptosis induced by chelation of intracellular zinc is associated with depletion of cellular reduced glutathione level in rat hepatocytes
    • T. Nakatani, M. Tawaramoto, D. Opare Kennedy, A. Kojima, and I. Matsui-Yuasa Apoptosis induced by chelation of intracellular zinc is associated with depletion of cellular reduced glutathione level in rat hepatocytes Chem. Biol. Interact. 125 2000 151 163
    • (2000) Chem. Biol. Interact. , vol.125 , pp. 151-163
    • Nakatani, T.1    Tawaramoto, M.2    Opare Kennedy, D.3    Kojima, A.4    Matsui-Yuasa, I.5
  • 38
    • 0027986662 scopus 로고
    • Markedly enhanced cytochrome P450 2E1 induction and lipid peroxidation is associated with severe liver injury in fish oil-ethanol-fed rats
    • A.A. Nanji, S. Zhao, S.M. Sadrzadeh, A.J. Dannenberg, S.R. Tahan, and D.J. Waxman Markedly enhanced cytochrome P450 2E1 induction and lipid peroxidation is associated with severe liver injury in fish oil-ethanol-fed rats Alcohol. Clin. Exp. Res. 18 1994 1280 1285
    • (1994) Alcohol. Clin. Exp. Res. , vol.18 , pp. 1280-1285
    • Nanji, A.A.1    Zhao, S.2    Sadrzadeh, S.M.3    Dannenberg, A.J.4    Tahan, S.R.5    Waxman, D.J.6
  • 39
    • 0028074476 scopus 로고
    • Alcohol and antioxidant systems
    • R. Nordmann Alcohol and antioxidant systems Alcohol Alcohol. 29 1994 513 522
    • (1994) Alcohol Alcohol. , vol.29 , pp. 513-522
    • Nordmann, R.1
  • 40
    • 0035968001 scopus 로고    scopus 로고
    • Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis
    • C.E. Outten, and T.V. O'Halloran Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis Science 292 2001 2488 2492
    • (2001) Science , vol.292 , pp. 2488-2492
    • Outten, C.E.1    O'Halloran, T.V.2
  • 41
    • 0141629349 scopus 로고    scopus 로고
    • Effects of zinc deficiency and supplementation on malondialdehyde and glutathione levels in blood and tissues of rats performing swimming exercise
    • A. Ozturk, A.K. Baltaci, R. Mogulkoc, E. Oztekin, A. Sivrikaya, E. Kurtoglu, and A. Kul Effects of zinc deficiency and supplementation on malondialdehyde and glutathione levels in blood and tissues of rats performing swimming exercise Biol. Trace Elem. Res. 94 2003 157 166
    • (2003) Biol. Trace Elem. Res. , vol.94 , pp. 157-166
    • Ozturk, A.1    Baltaci, A.K.2    Mogulkoc, R.3    Oztekin, E.4    Sivrikaya, A.5    Kurtoglu, E.6    Kul, A.7
  • 42
    • 0027182948 scopus 로고
    • Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice
    • R.D. Palmiter, E.P. Sandgren, D.M. Koeller, and R.L. Brinster Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice Mol. Cell Biol. 13 1993 5266 5275
    • (1993) Mol. Cell Biol. , vol.13 , pp. 5266-5275
    • Palmiter, R.D.1    Sandgren, E.P.2    Koeller, D.M.3    Brinster, R.L.4
  • 45
    • 0036189730 scopus 로고    scopus 로고
    • Advances in the structure and chemistry of metallothioneins
    • N. Romero-Isart, and M. Vasak Advances in the structure and chemistry of metallothioneins J. Inorg. Biochem. 88 2002 388 396
    • (2002) J. Inorg. Biochem. , vol.88 , pp. 388-396
    • Romero-Isart, N.1    Vasak, M.2
  • 46
    • 0028928331 scopus 로고
    • Effect of dietary zinc on lipid peroxidation, glutathione, protein thiols levels and superoxide dismutase activity in rat tissues
    • A.A. Shaheen, and A.A. el-Fattah Effect of dietary zinc on lipid peroxidation, glutathione, protein thiols levels and superoxide dismutase activity in rat tissues Int. J. Biochem. Cell Biol. 27 1995 89 95
    • (1995) Int. J. Biochem. Cell Biol. , vol.27 , pp. 89-95
    • Shaheen, A.A.1    El-Fattah, A.A.2
  • 48
    • 0036074141 scopus 로고    scopus 로고
    • Lipopolysaccharides in liver injury: Molecular mechanisms of Kupffer cell activation
    • G.L. Su Lipopolysaccharides in liver injury: molecular mechanisms of Kupffer cell activation Am. J. Physiol. Gastrointest. Liver Physiol. 283 2002 G256 G265
    • (2002) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.283
    • Su, G.L.1
  • 49
    • 0019013769 scopus 로고
    • Reactivation in vitro of zinc-requiring apo-enzymes by rat liver zinc-thionein
    • A.O. Udom, and F.O. Brady Reactivation in vitro of zinc-requiring apo-enzymes by rat liver zinc-thionein Biochem. J. 187 1980 329 335
    • (1980) Biochem. J. , vol.187 , pp. 329-335
    • Udom, A.O.1    Brady, F.O.2
  • 50
    • 0021988256 scopus 로고
    • Zinc absorption and leukocyte zinc in alcoholic and nonalcoholic cirrhosis
    • L.S. Valberg, P.R. Flanagan, C.N. Ghent, and M.J. Chamberlain Zinc absorption and leukocyte zinc in alcoholic and nonalcoholic cirrhosis Dig. Dis. Sci. 30 1985 329 333
    • (1985) Dig. Dis. Sci. , vol.30 , pp. 329-333
    • Valberg, L.S.1    Flanagan, P.R.2    Ghent, C.N.3    Chamberlain, M.J.4
  • 51
    • 0027394031 scopus 로고
    • The biochemical basis of zinc physiology
    • B.L. Vallee, and K.H. Falchuk The biochemical basis of zinc physiology Physiol. Rev. 73 1993 79 118
    • (1993) Physiol. Rev. , vol.73 , pp. 79-118
    • Vallee, B.L.1    Falchuk, K.H.2
  • 52
    • 0016706440 scopus 로고
    • Distribution of zinc in skeletal muscle and liver tissue in normal and dietary controlled alcoholic rats
    • J. Wang, and R.N. Pierson Jr. Distribution of zinc in skeletal muscle and liver tissue in normal and dietary controlled alcoholic rats J. Lab. Clin. Med. 85 1975 50 58
    • (1975) J. Lab. Clin. Med. , vol.85 , pp. 50-58
    • Wang, J.1    Pierson Jr., R.N.2
  • 53
    • 0034859820 scopus 로고    scopus 로고
    • Oxidation of zinc finger transcription factors: Physiological consequences
    • K.A. Webster, H. Prentice, and N.H. Bishopric Oxidation of zinc finger transcription factors: physiological consequences Antioxid. Redox Signal. 3 2001 535 548
    • (2001) Antioxid. Redox Signal. , vol.3 , pp. 535-548
    • Webster, K.A.1    Prentice, H.2    Bishopric, N.H.3
  • 54
    • 0034873674 scopus 로고    scopus 로고
    • Oxidation of zinc-binding cysteine residues in transcription factor proteins
    • D.E. Wilcox, A.D. Schenk, B.M. Feldman, and Y. Xu Oxidation of zinc-binding cysteine residues in transcription factor proteins Antioxid. Redox Signal. 3 2001 549 564
    • (2001) Antioxid. Redox Signal. , vol.3 , pp. 549-564
    • Wilcox, D.E.1    Schenk, A.D.2    Feldman, B.M.3    Xu, Y.4
  • 56
    • 0035344459 scopus 로고    scopus 로고
    • Nitric oxide selectively releases metals from the amino-terminal domain of metallothioneins: Potential role at inflammatory sites
    • K. Zangger, G. Oz, E. Haslinger, O. Kunert, and I.M. Armitage Nitric oxide selectively releases metals from the amino-terminal domain of metallothioneins: potential role at inflammatory sites FASEB J. 15 2001 1303 1305
    • (2001) FASEB J. , vol.15 , pp. 1303-1305
    • Zangger, K.1    Oz, G.2    Haslinger, E.3    Kunert, O.4    Armitage, I.M.5
  • 57
    • 0030693810 scopus 로고    scopus 로고
    • TUNEL-positive hepatocytes in alcoholic liver disease. a retrospective biopsy study using DNA nick end-labelling
    • M. Zhao, J.A. Laissue, and A. Zimmermann TUNEL-positive hepatocytes in alcoholic liver disease. A retrospective biopsy study using DNA nick end-labelling Virchows Arch. 431 1997 337 344
    • (1997) Virchows Arch. , vol.431 , pp. 337-344
    • Zhao, M.1    Laissue, J.A.2    Zimmermann, A.3
  • 58
    • 0035408265 scopus 로고    scopus 로고
    • Ethanol-induced apoptosis in mouse liver: Fas- and cytochrome c-mediated caspase-3 activation pathway
    • Z. Zhou, X. Sun, and Y.J. Kang Ethanol-induced apoptosis in mouse liver: Fas- and cytochrome c-mediated caspase-3 activation pathway Am. J. Pathol. 159 2001 329 338
    • (2001) Am. J. Pathol. , vol.159 , pp. 329-338
    • Zhou, Z.1    Sun, X.2    Kang, Y.J.3
  • 59
    • 0036521544 scopus 로고    scopus 로고
    • Metallothionein protection against alcoholic liver injury through inhibition of oxidative stress
    • Z. Zhou, X. Sun, and Y.J. Kang Metallothionein protection against alcoholic liver injury through inhibition of oxidative stress Exp. Biol. Med. (Maywood) 227 2002 214 222
    • (2002) Exp. Biol. Med. (Maywood) , vol.227 , pp. 214-222
    • Zhou, Z.1    Sun, X.2    Kang, Y.J.3
  • 60
    • 0036083963 scopus 로고    scopus 로고
    • Metallothionein-independent zinc protection from alcoholic liver injury
    • Z. Zhou, X. Sun, J.C. Lambert, J.T. Saari, and Y.J. Kang Metallothionein-independent zinc protection from alcoholic liver injury Am. J. Pathol. 160 2002 2267 2274
    • (2002) Am. J. Pathol. , vol.160 , pp. 2267-2274
    • Zhou, Z.1    Sun, X.2    Lambert, J.C.3    Saari, J.T.4    Kang, Y.J.5
  • 61
    • 0041422646 scopus 로고    scopus 로고
    • A critical involvement of oxidative stress in acute alcohol-induced hepatic TNF-alpha production
    • Z. Zhou, L. Wang, Z. Song, J.C. Lambert, C.J. McClain, and Y.J. Kang A critical involvement of oxidative stress in acute alcohol-induced hepatic TNF-alpha production Am. J. Pathol. 163 2003 1137 1146
    • (2003) Am. J. Pathol. , vol.163 , pp. 1137-1146
    • Zhou, Z.1    Wang, L.2    Song, Z.3    Lambert, J.C.4    McClain, C.J.5    Kang, Y.J.6
  • 62
    • 1942501608 scopus 로고    scopus 로고
    • Abrogation of nuclear factor-kappaB activation is involved in zinc inhibition of lipopolysaccharide-induced tumor necrosis factor-alpha production and liver injury
    • Z. Zhou, L. Wang, Z. Song, J.T. Saari, C.J. McClain, and Y.J. Kang Abrogation of nuclear factor-kappaB activation is involved in zinc inhibition of lipopolysaccharide-induced tumor necrosis factor-alpha production and liver injury Am. J. Pathol. 164 2004 1547 1556
    • (2004) Am. J. Pathol. , vol.164 , pp. 1547-1556
    • Zhou, Z.1    Wang, L.2    Song, Z.3    Saari, J.T.4    McClain, C.J.5    Kang, Y.J.6
  • 63
    • 19544364689 scopus 로고    scopus 로고
    • Zinc supplementation prevents alcoholic liver injury in mice through attenuation of oxidative stress
    • Z. Zhou, L. Wang, Z. Song, J.T. Saari, C.J. McClain, and Y.J. Kang Zinc supplementation prevents alcoholic liver injury in mice through attenuation of oxidative stress Am. J. Pathol. 166 2005 1681 1690
    • (2005) Am. J. Pathol. , vol.166 , pp. 1681-1690
    • Zhou, Z.1    Wang, L.2    Song, Z.3    Saari, J.T.4    McClain, C.J.5    Kang, Y.J.6


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