Ethanol-induced apoptosis in mouse liver: Fas- and cytochrome c-mediated caspase-3 activation pathway

American Journal of Pathology

Volumn 159, Issue 1, 2001, Pages 329-338

  Zhou, Zhanxiang ^a   Sun, Xiuhua ^a   Kang, Y James ^a,b  

^a University of Louisville School of Medicine   (United States)

^b JEWISH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; BENZOYLCARBONYL ASPARTYL GLUTAMYL VALYL ASPARTYL FLUOROMETHYL KETONE; BENZOYLCARBONYL-ASPARTYL-GLUTAMYL-VALYL-ASPARTYL-FLUOROMETHYL KETONE; CASP3 PROTEIN, MOUSE; CASPASE; CASPASE 3; CYSTEINE PROTEINASE INHIBITOR; CYTOCHROME C; FAS LIGAND; FASL PROTEIN, MOUSE; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; OLIGOPEPTIDE;

ANIMAL; APOPTOSIS; ARTICLE; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; IMMUNOLOGY; LIVER; MALE; METABOLISM; MOUSE; PHYSIOLOGY; TIME; TISSUE DISTRIBUTION;

ANIMALS; ANTIBODIES, MONOCLONAL; APOPTOSIS; CASPASE 3; CASPASES; CYSTEINE PROTEINASE INHIBITORS; CYTOCHROME C GROUP; ENZYME ACTIVATION; ETHANOL; FAS LIGAND PROTEIN; LIVER; MALE; MEMBRANE GLYCOPROTEINS; MICE; OLIGOPEPTIDES; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 0035408265     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)61699-9     Document Type: Article

References (42)

1. Nanji AA: Apoptosis and alcoholic liver disease. Semin Liver Dis 1998, 18:187-190
2. Slomiany BL, Piotrowski J, Piotrowski E, Slomiany A: Induction of buccal mucosal apoptosis with chronic alcohol ingestion. Biochem Mol Biol Int 1998, 44:381-389
3. Slomiany BL, Piotrowski J, Slomiany A: Chronic alcohol ingestion enhances tumor necrosis factor-alpha expression and salivary gland apoptosis. Alcohol Clin Exp Res 1997, 21:1530-1533
4. Piotrowski J, Piotrowski E, Slomiany A, Slomiany BL: Gastric mucosal apoptosis induced by ethanol: effect of antiulcer agents. Biochem Mol Biol Int 1997, 42:247-254
5. Zhang FX, Rubin R, Rooney TA: Ethanol induces apoptosis in cerebellar granule neurons by inhibiting insulin-like growth factor 1 signaling. J Neurochem 1998, 71:196-204
6. Wang J-F, Spitzer JJ: Alcohol-induced thymocyte apoptosis is accompanied by impaired mitochondrial function. Alcohol 1997, 14:99-105
7. Coiler SD, Wu WJ, Pruett SB: Endogenous glucocorticoids induced by a chemical stressor (ethanol) cause apoptosis in the spleen in B6C3F1 female mice. Toxicol Appl Pharmacol 1998, 148:176-182
8. Benedetti A, Brunelli E, Risicato R, Cilluffo T, Jezequel AM, Orlandi F: Subcellular changes and apoptosis induced by ethanol in rat liver. J Hepatol 1988, 6:137-143
9. Baroni GS, Marucci L, Benedetti A, Mancini R, Jezequel AM, Orlandi F: Chronic ethanol feeding increases apoptosis and cell proliferation in rat liver. J Hepatol 1994, 20:508-513
10. Yacoub LK, Fogt F, Griniuviene B, Nanji AA: Apoptosis and BcL-2 protein expression in experimental alcoholic liver disease in the rat. Alcohol Clin Exp Res 1995, 19:854-859
11. Kurose I, Higuchi H, Miura S, Saito H, Watanabe N, Hokari R, Hirokawa M, Takaishi M, Zeki S, Nakamura T, Ebimura H, Kato S, Ishii H: Oxidative stress-mediated apoptosis of hepatocytes exposed to acute ethanol intoxication. Hepatology 1997, 25:368-378
12. Sloamiany A, Piotrowski E, Grabska M, Piotrowski J, Sloamiany BL: Chronic ethanol-initiated apoptosis in hepatocytes is induced by changes in membrane biogenesis and intracellular transport. Alcohol Clin Exp Res 1999, 23:334-343
13. Mi L-J, Mak KM, Lieber CS: Attention of alcohol-induced apoptosis of hepatocytes in rat livers by polyenylphosphatidylcholine (PPC). Alcohol Clin Exp Res 2000, 24:207-212
14. Goldin RD, Hunt NC, Clark J, Wickramasinghe SN: Apoptotic bodies in a murine model of alcoholic liver disease: reversibility of ethanol-induced changes. J Pathol 1993, 171:73-76
15. Halsted C, Vilanueva J, Chandler CJ, Stabler SP, Allen RH, Muskhelishvill L, James SJ, Poirier L: Ethanol feeding of micropigs alters methionine metabolism and increases hepatocellular apoptosis and proliferation. Hepatology 1996, 23:497-505
16. Jiang Z, Liu Y, Smith LO, Bonkovsky H, Baker S: Frequency and distribution of DNA fragmentation as a marker of cell death in chronic liver diseases. Virchows Arch 1997, 431:189-194
17. Zhao M, Laissue JA, Zimmermann A: TUNEL-positive hepatocytes in alcoholic liver disease. A retrospective biopsy study using DNA nick end-labeling. Virchows Arch 1997, 431:337-344
18. Cohen GM: Caspases: the executioners of apoptosis. Biochem J 1997, 326:1-16
19. Faleiro L, Kobayashi R, Fearnhead H, Lazebnik Y: Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells. EMBO J 1997, 16:2271-2281
20. Kumar S: The apoptotic cysteine protease CPP32. Int J Biochem Cell Biol 1997, 29:393-396
21. Porter AG, Janicke RU: Emerging roles of caspase-3 in apoptosis. Cell Death Differ 1999, 6:99-104
22. Nagata S, Golstein P: The Fas death factor Science 1995, 267:1449-1456
23. Cai J, Yang J, Jones DP: Mitochondrial control of apoptosis: the role of cytochrome c. Biochim Biophys Acta 1998, 1366:139-149
24. Deaciuc IV, Fortunate F, D'Souza NB, Hill DB, Schmidt J, Lee EY, McClain CJ: Modulation of caspase-3 activity and Fas ligand mRNA expression in rat liver cells in vivo by alcohol and lipopolysaccharide. Alcohol Clin Exp Res 1999, 23:349-356
25. Galle PR, Hofmann WJ, Walczak H, Schaller H, Otto G, Stremmel W, Krammer PH, Runkel L: Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage. J Exp Med 1995, 182:1223-1230
26. Chandler JM, Cohen GM, MacFarlane M: Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver. J Biol Chem 1998, 273:10815-10818
27. Yaoita H, Ogawa K, Maehara K, Maruyama Y: Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor Circulation 1998, 97:276-281
28. Farber A, Connors JP, Friedlander RM, Wager RJ, Powell RJ, Cronenwett JL: A specific inhibitor of apoptosis decreases tissue injury after intestinal ischemia-reperfusion in mice. J Vasc Surg 1999, 30:752-760
29. Cursio R, Gugenheim J, Ricci JH, Crenesse D, Rostagno P, Maulon L, Saint-Paul M, Fernard B, Auberger P: A caspase inhibitor protects rats lethal normothermic liver ischemia by inhibition of liver apoptosis. FASEB J 1999, 13:253-261
30. Nakamura T, Ueda Y, Juan Y, Katsuda S, Takahashi H, Koh E: Fas-mediated apoptosis in adriamycin-induced cardiomyopathy in rats: in vivo study. Circulation 2000, 102:572-578
31. Suarez-Pinzon WL, Power RF, Rabinovitch A: Fas ligand-mediated mechanisms are involved in autoimmune destruction of islet beta cells in non-obese diabetic mice. Diabetologia 2000, 43:1149-1156
32. Carson EJ, Prutt SB: Development and characterization of a binge drinking model in mice for evaluation of the immunological effects of ethanol. Alcohol Clin Exp Res 1996, 20:132-138
33. Buckley AR, Crowe PD, Russell DH: Rapid activation of protein kinase C in isolated rat liver nuclei by prolactin, a known hepatic mitogen. Proc Natl Acad Sci USA 1988, 85:8649-8653
34. Slomiany BL, Piotrowski J, Piotrowski E, Slomiany A: Activation of apoptotic caspase-3 and nitric oxide synthase-2 in buccal mucosa with chronic alcohol ingestion. Biochem Mol Biol Int 1998, 45:1199-1209
35. Deuciuc IV, Fortunato F, D'Souza NB, Hill DB, Schmidt J, Lee EY, McClain CJ: Modulation of caspase-3 activity and Fas ligand mRNA expression in rat liver cells in vivo by alcohol and lipopolysaccharide Alcohol Clin Exp Res 1999, 23:349-356
36. Krajewska M, Wang HG, Krajewski S, Zapata JM, Shabaik A, Gascoyne R, Reed JC: Immunohistochemical analysis of in vivo pattern of expression of CPP32 (caspase-3), a cell death protease. Cancer Res 1997, 57:1605-1613
37. Tang DG, Li L, Zhu Z, Joshi B: Apoptosis in the absence of cytochrome c accumulation in the cytosol. Biochem Biophys Res Commun 1998, 242:380-384
38. Ogasawara J, Watanabe-Fukunaga R, Adachi M, Matsuzawa A, Kasugal T, Kitamura Y, Itoh N: Lethal effect of anti-Fas antibody in mice. Nature 1993, 364:806-809
39. Leist M, Gantner F, Kunstle G, Bohlinger I, Tegs G, Bluethmann H, Wendel A: The 55-kD tumor necrosis factor receptor and CD95 independently signal murine heoatocyte apoptosis and subsequently liver failure. Mol Med 1996, 2:109-124
40. Jones RA, Johnson VL, Buck JN, Dobrota M, Hinton RH, Chow SC, Kass GN: Fas-mediated apoptosis in mouse hepatocytes involves the processing and activation of caspases. Hepatology 1998, 27:1632-1642
41. Bajt ML, Lawson JA, Vonderfecht SL, Gujral JS, Jaeschke H: Protection against Fas receptor-mediated apoptosis in hepatocytes and nonparenchymal cells by a caspase-8 inhibitor in vivo: evidence for a postmitochondrial processing of caspase-8. Toxicol Sci 2000, 58: 109-117
42. Liu X, Kim CN, Yang J, Jemmerson R, Wang X: Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 1996, 86:147-157