Apoptosis induced by chelation of intracellular zinc is associated with depletion of cellular reduced glutathione level in rat hepatocytes

Chemico-Biological Interactions

Volumn 125, Issue 3, 2000, Pages 151-163

  Nakatani, Teruyo ^a   Tawaramoto, Maki ^a   Opare Kennedy, David ^a   Kojima, Akiko ^a   Matsui Yuasa, Isao ^a  

^a Osaka Prefecture University   (Japan)

Author keywords

Apoptosis; Diethylenetriamine pentaacetic acid (DTPA); Hepatocytes; N, N, N', N' tetrakis(2 pyridylmethyl) ethylenediamine (TPEN); Reduced glutathione (GSH); Zinc (Zn2+)

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; CASPASE 3; CHELATING AGENT; GLUTATHIONE; N,N,N',N' TETRAKIS(2 PYRIDYLMETHYL)ETHYLENEDIAMINE; PENTETIC ACID; ZINC ION; ZINC SULFATE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CHELATION; CONTROLLED STUDY; ENZYME ACTIVITY; IN VITRO STUDY; LIVER CELL; NONHUMAN; RAT;

ACETYLCYSTEINE; ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; CELL NUCLEUS; CHELATING AGENTS; DRUG INTERACTIONS; ETHYLENEDIAMINES; GLUTATHIONE; LIVER; MALE; RATS; RATS, SPRAGUE-DAWLEY; ZINC;

EID: 0034653559     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(99)00166-0     Document Type: Article

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