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Volumn 46, Issue 39, 2005, Pages 6683-6686

A highly efficient synthesis of antiobestic ligand GW501516 for the peroxisome proliferator-activated receptor δ through in situ protection of the phenol group by reaction with a Grignard reagent

(2) Ham, Jungyeob a Kang, Heonjoong a

a Seoul National University (South Korea)

Author keywords

Antiobestic drug; Grignard reagent; GW501516; One pot synthesis; PPAR ; Sulfide

Indexed keywords

4 IODO 2 METHYLPHENOL; [2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; ANTIOBESITY AGENT; CRESOL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PHENOL; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; CHEMICAL REACTION; DRUG SYNTHESIS; GRIGNARD REACTION; MOLECULAR RECOGNITION; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 23944489818 PISSN: 00404039 EISSN: None Source Type: Journal
DOI: 10.1016/j.tetlet.2005.07.145 Document Type: Article

Times cited : (13)

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