Short-term leptin treatment increases fatty acids uptake and oxidation in muscle of high fat-fed rats

Metabolism: Clinical and Experimental

Volumn 54, Issue 9, 2005, Pages 1218-1224

  Todd, Mark K ^a   Yaspelkis III, Ben B ^b   Turcotte, Lorraine P ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 14; FAT; FATTY ACID; GLUCOSE; INSULIN; LEPTIN; PALMITIC ACID; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIET; DRUG EFFECT; ENERGY EXPENDITURE; ESTERIFICATION; FATTY ACID METABOLISM; FATTY ACID OXIDATION; FATTY ACID TRANSPORT; FEEDING; FOOD INTAKE; GLUCOSE TRANSPORT; INJECTION; INSULIN SENSITIVITY; LIMB PERFUSION; LIPID DIET; LIPOGENESIS; MALE; MEASUREMENT; MUSCLE; NONHUMAN; PRIORITY JOURNAL; RAT; SHORT COURSE THERAPY;

ANIMALS; CARBON RADIOISOTOPES; DIETARY FATS; ENERGY METABOLISM; ESTERIFICATION; INSULIN; INSULIN RESISTANCE; LEPTIN; MALE; MUSCLE, SKELETAL; OXIDATION-REDUCTION; PALMITATES; RATS; RATS, WISTAR; TRIGLYCERIDES;

EID: 23944454863     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2005.04.007     Document Type: Article

References (38)

1. P.J. Randle, C.N. Hales, and P.B. Garland The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus Lancet i 1963 785 789
2. J.K. Kim, J.K. Wi, and J.H. Youn Plasma free fatty acids decrease insulin-stimulated skeletal muscle glucose uptake by suppressing glycolysis in conscious rats Diabetes 45 1996 446 453
3. P.A. Hansen, D.H. Han, and B.A. Marshall A high fat diet impairs stimulation of glucose transport in muscle. Functional evaluation of potential mechanisms J Biol Chem 273 1998 26157 26163
4. J.Y. Kim, L.A. Nolte, and P.A. Hansen High-fat diet-induced muscle insulin resistance: relationship to visceral fat mass Am J Physiol Regul Integr Comp Physiol 279 2000 R2057 R2065
5. M. Krssak, K. Falk Petersen, and A. Dresner Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study Diabetologia 42 1999 113 116
6. D.A. Pan, S. Lillioja, and A.D. Kriketos Skeletal muscle triglyceride levels are inversely related to insulin action Diabetes 46 1997 983 988
7. M.K. Todd, A.L. Hevener, and L.P. Turcotte Troglitazone normalizes plasma FA levels in high fat fed rats by increasing FA uptake in skeletal muscle Diabetes 50 2002 A337
8. J.D. McGarry What if Minkowski had been ageusic? An alternative angle on diabetes Science 258 1992 766 770
9. Y. Ogawa, H. Masuzaki, and K. Hosoda Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressing leptin Diabetes 48 1999 1822 1829
10. C.A. Baile, M.A. Della-Fera, and R.J. Martin Regulation of metabolism and body fat mass by leptin Annu Rev Nutr 20 2000 105 127
11. T.W. Stephens, M. Basinski, and P.K. Bristow The role of neuropeptide Y in the antiobesity action of the obese gene product Nature 377 1995 530 532
12. L.A. Tartaglia, M. Dembski, and X. Weng Identification and expression cloning of a leptin receptor, OB-R Cell 83 1995 1263 1271
13. N. Ghilardi, S. Ziegler, and A. Wiestner Defective STAT signaling by the leptin receptor in diabetic mice Proc Natl Acad Sci U S A 93 1996 6231 6235
14. D.M. Muoio, G.L. Dohm, and F.T. Fiedorek Jr. Leptin directly alters lipid partitioning in skeletal muscle Diabetes 46 1997 1360 1363
15. L. Berti, M. Kellerer, and E. Capp Leptin stimulates glucose transport and glycogen synthesis in C2C12 myotubes: evidence for a P13-kinase mediated effect Diabetologia 40 1997 606 609
16. G.R. Steinberg, A. Bonen, and D.J. Dyck Fatty acid oxidation and triacylglycerol hydrolysis are enhanced after chronic leptin treatment in rats Am J Physiol Endocrinol Metab 282 2002 E593 E600
17. G.R. Steinberg, D.J. Dyck, and J. Calles-Escandon Chronic leptin administration decreases fatty acid uptake and fatty acid transporters in rat skeletal muscle J Biol Chem 277 2002 8854 8860
18. M.K. Singh, A.D. Krisan, and A.M. Crain High-fat diet and leptin treatment alter skeletal muscle insulin-stimulated phosphatidylinositol 3-kinase activity and glucose transport Metabolism 52 2003 1196 1205
19. G.R. Steinberg, and D.J. Dyck Development of leptin resistance in rat soleus muscle in response to high-fat diets Am J Physiol Endocrinol Metab 279 2000 E1374 E1382
20. L.P. Turcotte, J.R. Swenberger, and M.Z. Tucker Training-induced elevation in FABP(PM) is associated with increased palmitate use in contracting muscle J Appl Physiol 87 1999 285 293
21. L.P. Turcotte, J.R. Swenberger, and M. Zavitz Tucker Increased fatty acid uptake and altered fatty acid metabolism in insulin-resistant muscle of obese Zucker rats Diabetes 50 2001 1389 1396
22. L.P. Turcotte, J.R. Swenberger, and A.J. Yee High carbohydrate availability increases LCFA uptake and decreases LCFA oxidation in perfused muscle Am J Physiol Endocrinol Metab 282 2002 E177 E183
23. S. Iossa, M.P. Mollica, and L. Lionetti Skeletal muscle oxidative capacity in rats fed high-fat diet Int J Obes Relat Metab Disord 26 2002 65 72
24. D.M. Muoio, G.L. Dohm, and E.B. Tapscott Leptin opposes insulin's effects on fatty acid partitioning in muscles isolated from obese ob/ob mice Am J Physiol 276 1999 E913 E921
25. D.J. Dyck, G. Steinberg, and A. Bonen Insulin increases FA uptake and esterification but reduces lipid utilization in isolated contracting muscle Am J Physiol Endocrinol Metab 281 2001 E600 E607
26. F. Tremblay, C. Lavigne, and H. Jacques Defective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/protein kinase B and atypical protein kinase C (ζ/λ) activities Diabetes 50 2001 1901 1910
27. M. Taouis, C. Dagou, and C. Ster N-3 polyunsaturated fatty acids prevent the defect of insulin receptor signaling in muscle Am J Physiol Endocrinol Metab 282 2002 E664 E671
28. B.D. Hegarty, G.J. Cooney, and E.W. Kraegen Increased efficiency of fatty acid uptake contributes to lipid accumulation in skeletal muscle of high fat-fed insulin-resistant rats Diabetes 51 2002 1477 1484
29. M.Z. Tucker, and L.P. Turcotte Brief food restriction increases FA oxidation and glycogen synthesis under insulin-stimulated conditions Am J Physiol Regul Integr Comp Physiol 282 2002 R1210 R1218
30. G.D. Cartee, and D.J. Dean Glucose transport with brief dietary restriction: heterogeneous responses in muscles Am J Physiol 266 1994 E946 E952
31. G.R. Steinberg, A.C. Smith, and S. Wormald Endurance training partially reverses dietary-induced leptin resistance in rodent skeletal muscle Am J Physiol Endocrinol Metab 286 2004 E57 E63
32. Y. Minokoshi, Y.B. Kim, and O.D. Peroni Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase Nature 415 2002 339 343
33. G.R. Steinberg, J.W. Rush, and D.J. Dyck AMPK expression and phosphorylation are increased in rodent muscle after chronic leptin treatment Am J Physiol Endocrinol Metab 284 2003 E648 E654
34. M.A. Raney, A.J. Yee, and M.K. Todd AMPK activation is not critical in the regulation of muscle FA uptake and oxidation during low-intensity muscle contraction Am J Physiol Endocrinol Metab 288 2005 E592 E598
35. L. Berti, and S. Gammeltoft Leptin stimulates glucose uptake in C2C12 muscle cells by activation of ERK2 Mol Cell Endocrinol 157 1999 121 130
36. L.P. Turcotte, M.R. Raney, and M.K. Todd ERK1/2 inhibition prevents contraction-induced increase in plasma membrane FAT/CD36 content and FA uptake in rodent muscle Acta Physiol Scand 184 2005 131 139
37. B.B. Yaspelkis III, J.R. Davis, and M. Saberi Leptin administration improves skeletal muscle insulin responsiveness in diet-induced insulin-resistant rats Am J Physiol Endocrinol Metab 280 2001 E130 E142
38. B.B. Yaspelkis III, M.K. Singh, and A.D. Krisan Chronic leptin treatment enhances insulin-stimulated glucose disposal in skeletal muscle of high-fat fed rodents Life Sci 74 2004 1801 1816