메뉴 건너뛰기




Volumn 45, Issue 4, 1996, Pages 446-453

Plasma free fatty acids decrease insulin-stimulated skeletal muscle glucose uptake by suppressing glycolysis in conscious rats

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLGLUCOSE; DEOXYGLUCOSE; FATTY ACID; GLUCOSE; HEPARIN; INSULIN; INTRALIPID;

EID: 0029962286     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.45.4.446     Document Type: Article
Times cited : (87)

References (39)
  • 1
    • 0019995650 scopus 로고
    • Hepatic and peripheral insulin resistance: A common feature of type 2 (non-insulin-dependent) and type 1 (insulin-dependent) diabetes mellitus
    • DeFronzo RA, Simonson D, Ferranmni E: Hepatic and peripheral insulin resistance: a common feature of type 2 (non-insulin-dependent) and type 1 (insulin-dependent) diabetes mellitus Diabetologia 23.313-319, 1982
    • (1982) Diabetologia , vol.23 , pp. 313-319
    • DeFronzo, R.A.1    Simonson, D.2    Ferranmni, E.3
  • 2
    • 0021145335 scopus 로고
    • A comparison of the relative effects of obesity and non-insulin-dependent diabetes mellitus on in vivo insulin-stimulated glucose utilization
    • Hollenbeck CB, Chen YI, Reaven GM: A comparison of the relative effects of obesity and non-insulin-dependent diabetes mellitus on in vivo insulin-stimulated glucose utilization, Diabetes 33:622-626, 1984
    • (1984) Diabetes , vol.33 , pp. 622-626
    • Hollenbeck, C.B.1    Chen, Y.I.2    Reaven, G.M.3
  • 5
    • 50549202600 scopus 로고
    • The glucose fatty acid cycle, its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
    • Randle PJ, Garland PB, Hales CN, Newsholme EA. The glucose fatty acid cycle, its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1:785-789, 1963
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3    Newsholme, E.A.4
  • 6
    • 0025732945 scopus 로고
    • Effects of glycogen stores and non-esterified falty acid availability on insulin-stimulated glucose metabolism and tissue pyruvate dehydrogenase activity in the rat
    • Kruszynska YT, McCormack JG, McIntyre N: Effects of glycogen stores and non-esterified falty acid availability on insulin-stimulated glucose metabolism and tissue pyruvate dehydrogenase activity in the rat. Diabetologia 34:205-211, 1991
    • (1991) Diabetologia , vol.34 , pp. 205-211
    • Kruszynska, Y.T.1    McCormack, J.G.2    McIntyre, N.3
  • 7
    • 0027218865 scopus 로고
    • Interaction between glucose and free fatty acid metabolism in human skeletal muscle
    • Kelley DE, Mokan M, Simoneau J-A, Mandarino LI: Interaction between glucose and free fatty acid metabolism in human skeletal muscle, J Clin Invest 92.91-98, 1993
    • (1993) J Clin Invest , vol.92 , pp. 91-98
    • Kelley, D.E.1    Mokan, M.2    Simoneau, J.-A.3    Mandarino, L.I.4
  • 8
    • 0017776141 scopus 로고
    • Inhibition of glucose uptake and glyeogenolysis by availability of oleate in well-oxygenated perfused skeletal muscle
    • Rennie MJ, Holloszy JO: Inhibition of glucose uptake and glyeogenolysis by availability of oleate in well-oxygenated perfused skeletal muscle. Biochem J 168.161-170, 1977
    • (1977) Biochem J , vol.168 , pp. 161-170
    • Rennie, M.J.1    Holloszy, J.O.2
  • 9
    • 0022393563 scopus 로고
    • Effects of starvation and exercise on concentrations of citrate, hexose phosphates and glycogen in skeletal muscle and heart: Evidence for selective operation of the glucose-fatty acid cycle
    • Zorzano A, Balon TW, Brady LJ, Rivera P, Garetto LP, Young JC, Goodman MN, Ruderman NB: Effects of starvation and exercise on concentrations of citrate, hexose phosphates and glycogen in skeletal muscle and heart: evidence for selective operation of the glucose-fatty acid cycle. Biochem J 232:580-591, 1985
    • (1985) Biochem J , vol.232 , pp. 580-591
    • Zorzano, A.1    Balon, T.W.2    Brady, L.J.3    Rivera, P.4    Garetto, L.P.5    Young, J.C.6    Goodman, M.N.7    Ruderman, N.B.8
  • 10
    • 0025766692 scopus 로고
    • Palnutate stimulates glucose transport in rat adipocytes by a mechanism involving translocation of the insulin-sensitive glucose transporter (GLUT4)
    • Hardy RW, Ladenson JH, Henriksen EJ, Holloszy JO, McDonald JM: Palnutate stimulates glucose transport in rat adipocytes by a mechanism involving translocation of the insulin-sensitive glucose transporter (GLUT4). Biochem Biophys Res Commun 177:343-349, 1991
    • (1991) Biochem Biophys Res Commun , vol.177 , pp. 343-349
    • Hardy, R.W.1    Ladenson, J.H.2    Henriksen, E.J.3    Holloszy, J.O.4    McDonald, J.M.5
  • 11
    • 0016290713 scopus 로고
    • Glucose metabolism in rat skeletal muscle at rest. effect of starvation, diabetes, ketone bodies, and free fatty acids
    • Goodman MN, Berger M, Ruderman NB: Glucose metabolism in rat skeletal muscle at rest. effect of starvation, diabetes, ketone bodies, and free fatty acids. Diabetes 23:881-888, 1974
    • (1974) Diabetes , vol.23 , pp. 881-888
    • Goodman, M.N.1    Berger, M.2    Ruderman, N.B.3
  • 13
    • 0028342686 scopus 로고
    • Mechanisms of fatty acid-induced inhibition of glucose uptake
    • Boden G. Chen X, Ruiz J, White JV. Rossetti L: Mechanisms of fatty acid-induced inhibition of glucose uptake. J Clin Invest 93:2438-2446, 1994
    • (1994) J Clin Invest , vol.93 , pp. 2438-2446
    • Boden, G.1    Chen, X.2    Ruiz, J.3    White, J.V.4    Rossetti, L.5
  • 14
    • 0028207988 scopus 로고
    • Glucose-fatty acid cycle operates in humans at the levels of both whole body and skeletal muscle during low and high physiological plasma insulin concentrations
    • Vaag AA, Handberg A, Skott P, Richter EA, Beck-Nielsen H: Glucose-fatty acid cycle operates in humans at the levels of both whole body and skeletal muscle during low and high physiological plasma insulin concentrations Eur J Endocrinol 130:70-79, 1994
    • (1994) Eur J Endocrinol , vol.130 , pp. 70-79
    • Vaag, A.A.1    Handberg, A.2    Skott, P.3    Richter, E.A.4    Beck-Nielsen, H.5
  • 15
    • 0025835909 scopus 로고
    • Effect of free fatty acids on glucose uptake and nonoxidative glycolysis across human forearm tissues in the basal state and during insulin stimulation
    • Yki-Jarvinen H, Puhakainen I, Koivisto VA: Effect of free fatty acids on glucose uptake and nonoxidative glycolysis across human forearm tissues in the basal state and during insulin stimulation. J Clin Endocrinol Metab 72:1268-1277, 1991
    • (1991) J Clin Endocrinol Metab , vol.72 , pp. 1268-1277
    • Yki-Jarvinen, H.1    Puhakainen, I.2    Koivisto, V.A.3
  • 16
    • 0025325555 scopus 로고
    • Physiological levels of plasma non-esterified fatty acids impair forearm glucose uptake in normal man
    • Walker M, Fulcher GR, Catalano C, Petranyi G. Orskov H. Alberti KGMM: Physiological levels of plasma non-esterified fatty acids impair forearm glucose uptake in normal man Clin Sci 79:167-174, 1990
    • (1990) Clin Sci , vol.79 , pp. 167-174
    • Walker, M.1    Fulcher, G.R.2    Catalano, C.3    Petranyi, G.4    Orskov, H.5    Alberti, K.G.M.M.6
  • 17
    • 0026517191 scopus 로고
    • Effect of increased free fatty acid supply on glucose metabolism and skeletal muscle glycogen synthase activity in normal man
    • Johnson AB, Argyraki M, Thow JC, Cooper BG, Fulcher G, Taylor R Effect of increased free fatty acid supply on glucose metabolism and skeletal muscle glycogen synthase activity in normal man. Clin Sci 82:219-226, 1992
    • (1992) Clin Sci , vol.82 , pp. 219-226
    • Johnson, A.B.1    Argyraki, M.2    Thow, J.C.3    Cooper, B.G.4    Fulcher, G.5    Taylor, R.6
  • 19
    • 0026040783 scopus 로고
    • Effect of glycemia and nonesterified fatty acids on forearm glucose uptake in normal humans
    • Walker M, Fulcher GR, Sum CF, Orskov H, Alberti KGMM: Effect of glycemia and nonesterified fatty acids on forearm glucose uptake in normal humans. Am J Physiol 261:E304-E311, 1991
    • (1991) Am J Physiol , vol.261
    • Walker, M.1    Fulcher, G.R.2    Sum, C.F.3    Orskov, H.4    Alberti, K.G.M.M.5
  • 20
    • 0023908033 scopus 로고
    • Effect of elevated free fatty acids on glucose oxidation in normal humans
    • Wolfe BM, Klein S, Peters EJ, Schmidt BF, Wolfe RR: Effect of elevated free fatty acids on glucose oxidation in normal humans Metabolism 37:323-329, 1988
    • (1988) Metabolism , vol.37 , pp. 323-329
    • Wolfe, B.M.1    Klein, S.2    Peters, E.J.3    Schmidt, B.F.4    Wolfe, R.R.5
  • 24
    • 0026007729 scopus 로고
    • Effect of increased plasma free fatty acid concentrations on muscle metabolism in exercising men
    • Hargreaves M, Kiens B, Richter EA. Effect of increased plasma free fatty acid concentrations on muscle metabolism in exercising men. J Appl Physiol 70:194-201, 1991
    • (1991) J Appl Physiol , vol.70 , pp. 194-201
    • Hargreaves, M.1    Kiens, B.2    Richter, E.A.3
  • 26
    • 0028327182 scopus 로고
    • Time courses of changes in hepatic and skeletal muscle insulin action and GLUT4 protein in skeletal muscle after STZ injection
    • Youn JH, Kim JK, Buchanan TA. Time courses of changes in hepatic and skeletal muscle insulin action and GLUT4 protein in skeletal muscle after STZ injection. Diabetes 43:564-571, 1994
    • (1994) Diabetes , vol.43 , pp. 564-571
    • Youn, J.H.1    Kim, J.K.2    Buchanan, T.A.3
  • 27
    • 0027316021 scopus 로고
    • Fasting does not impair insulin-stimulated glucose uptake but alters intracellular glucose metabolism in conscious rats
    • Youn JH, Buchanan TA: Fasting does not impair insulin-stimulated glucose uptake but alters intracellular glucose metabolism in conscious rats. Diabetes 42:757-763, 1993
    • (1993) Diabetes , vol.42 , pp. 757-763
    • Youn, J.H.1    Buchanan, T.A.2
  • 28
    • 0028941479 scopus 로고
    • Assessment of insulin's effects on extracellular glucose distribution and glucose transport activity in conscious rats
    • Youn JH, Kim JK, Steil G: Assessment of insulin's effects on extracellular glucose distribution and glucose transport activity in conscious rats Am J Physiol 268:E712-E721, 1995
    • (1995) Am J Physiol , vol.268
    • Youn, J.H.1    Kim, J.K.2    Steil, G.3
  • 29
    • 0026651713 scopus 로고
    • Enhanced glucose tolerance in spontaneously pertensive rats; pancreatic B-cell hyperfunction with normal insulin sensitivity
    • Buchanan TA, Youn JH: Enhanced glucose tolerance in spontaneously pertensive rats; pancreatic B-cell hyperfunction with normal insulin sensitivity. Diabetes 41:872-878, 1992
    • (1992) Diabetes , vol.41 , pp. 872-878
    • Buchanan, T.A.1    Youn, J.H.2
  • 30
    • 0021378450 scopus 로고
    • Adrenalectomy reverses insulin resistance in muscle from obese (ob/ob) mice
    • Ohshima K, Shargill NS, Chan TM, Bray GA: Adrenalectomy reverses insulin resistance in muscle from obese (ob/ob) mice. Am J Physiol 246:E193-E197, 1984
    • (1984) Am J Physiol , vol.246
    • Ohshima, K.1    Shargill, N.S.2    Chan, T.M.3    Bray, G.A.4
  • 31
    • 0025376250 scopus 로고
    • Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake
    • Rossetti L, Giaccari A: Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake. J Clin Invest 85.1785-1792, 1990
    • (1990) J Clin Invest , vol.85 , pp. 1785-1792
    • Rossetti, L.1    Giaccari, A.2
  • 32
    • 0000190157 scopus 로고
    • D-glucose-6-phosphate and D-fructose-6-phosphate
    • Michal G: D-glucose-6-phosphate and D-fructose-6-phosphate. Methods Enzyme Anal 6:191-198, 1985
    • (1985) Methods Enzyme Anal , vol.6 , pp. 191-198
    • Michal, G.1
  • 33
    • 0025946462 scopus 로고
    • Decreased in vivo glucose uptake but normal expression of GLUT1 and GLUT4 in skeletal muscle of diabetic rats
    • Kahn BB, Rossetti L, Lodish HF, Charron MJ: Decreased in vivo glucose uptake but normal expression of GLUT1 and GLUT4 in skeletal muscle of diabetic rats. J Clin Invest 87:2197-2206, 1991
    • (1991) J Clin Invest , vol.87 , pp. 2197-2206
    • Kahn, B.B.1    Rossetti, L.2    Lodish, H.F.3    Charron, M.J.4
  • 34
    • 0013773447 scopus 로고
    • Regulation of glucose uptake by muscle: Effects of alloxan-diabetes, starvation, hypophysectomy and adrenalectomy, and of fatty acids, ketone bodies and pyruvate, on the glyeerol output and concentrations of free fatty acids, long-chain fatty acylcoenzyme A, glycerol phosphate and citrate-cycle intermediates in rat heart and aphragm muscles
    • Garland PB, Randle PJ: Regulation of glucose uptake by muscle: effects of alloxan-diabetes, starvation, hypophysectomy and adrenalectomy, and of fatty acids, ketone bodies and pyruvate, on the glyeerol output and concentrations of free fatty acids, long-chain fatty acylcoenzyme A, glycerol phosphate and citrate-cycle intermediates in rat heart and aphragm muscles Biochem J 93:678-687, 1964
    • (1964) Biochem J , vol.93 , pp. 678-687
    • Garland, P.B.1    Randle, P.J.2
  • 35
    • 0017341862 scopus 로고
    • Effect of acetoacetete on glucose metabolism in the soleus and extensor digitorum longus muscles of the rat
    • Maizels EZ, Ruderman NB, Goodman MN, Lau D: Effect of acetoacetete on glucose metabolism in the soleus and extensor digitorum longus muscles of the rat Biochem J 162:557-568, 1977
    • (1977) Biochem J , vol.162 , pp. 557-568
    • Maizels, E.Z.1    Ruderman, N.B.2    Goodman, M.N.3    Lau, D.4
  • 36
    • 0017375420 scopus 로고
    • Effect of citrate on the activities of phosphofructokinase from nervous and muscle tissue from different animals and its relationship to the regulation of glycolysis
    • Newsholme EA, Sugden PH, Williams T: Effect of citrate on the activities of phosphofructokinase from nervous and muscle tissue from different animals and its relationship to the regulation of glycolysis. Biochem J 166:123-129, 1977
    • (1977) Biochem J , vol.166 , pp. 123-129
    • Newsholme, E.A.1    Sugden, P.H.2    Williams, T.3
  • 37
    • 0025314895 scopus 로고
    • Effects of non-esterified fatty acid availability on insulin stimulated glucose utilization and tissue pyruvate dehydrogenase activity in the rat
    • Kruszynska YT, McCormack JG, McIntyre N: Effects of non-esterified fatty acid availability on insulin stimulated glucose utilization and tissue pyruvate dehydrogenase activity in the rat. Diabetologia 33:396-402, 1990
    • (1990) Diabetologia , vol.33 , pp. 396-402
    • Kruszynska, Y.T.1    McCormack, J.G.2    McIntyre, N.3
  • 38
    • 0023739445 scopus 로고
    • Effects of nonesterifled fatty acids availability on tissue-specific glucose utilization in rats in vivo
    • Jenkins AB, Storlien LH, Chisholm DJ, Kraegen EW: Effects of nonesterifled fatty acids availability on tissue-specific glucose utilization in rats in vivo. J Clin Invest 82:293-299, 1988
    • (1988) J Clin Invest , vol.82 , pp. 293-299
    • Jenkins, A.B.1    Storlien, L.H.2    Chisholm, D.J.3    Kraegen, E.W.4
  • 39
    • 0024851469 scopus 로고
    • In vitro study of human skeletal muscle strips: Effect of nonesterified fatty acid supply on glucose storage
    • Argyraki M, Wright PD, Venables CW, Proud G, Taylor R: In vitro study of human skeletal muscle strips: effect of nonesterified fatty acid supply on glucose storage. Metabolism 38:1183-1187, 1989
    • (1989) Metabolism , vol.38 , pp. 1183-1187
    • Argyraki, M.1    Wright, P.D.2    Venables, C.W.3    Proud, G.4    Taylor, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.