Kinetic folding mechanism of PDZ2 from PTP-BL

Protein Engineering, Design and Selection

Volumn 18, Issue 8, 2005, Pages 389-395

  Gianni, Stefano ^a   Calosci, Nicoletta ^a   Aelen, Jan M A ^b   Vuister, Geerten W ^b   Brunori, Maurizio ^a   Travaglini Allocatelli, Carlo ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

Chevron plot; Hammond effect; Intermediate; Protein folding; Transition state

Indexed keywords

DATA ACQUISITION; FLUORESCENCE; RATE CONSTANTS; REACTION KINETICS; SODIUM COMPOUNDS;

CHEVRON PLOT; DENATURANT CONCENTRATION; HAMMOND EFFECT; INTERMEDIATE; KINETIC FOLDING MECHANISM; PROTEIN FOLDING; PROTEIN-INTERACTION MODULES; TRANSITION STATE;

PROTEINS;

PDZ PROTEIN; PROTEIN TYROSINE PHOSPHATASE 1B;

ARTICLE; MOLECULAR DYNAMICS; MUTATION; PH; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN VARIANT; WILD TYPE;

AMINO ACID SUBSTITUTION; CIRCULAR DICHROISM; CLONING, MOLECULAR; FLUORESCENT DYES; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE-PHOSPHATASE; RECOMBINANT PROTEINS; SULFATES; THERMODYNAMICS; UREA;

EID: 23944452163     PISSN: 17410126     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/gzi047     Document Type: Article

References (45)

1. Bai,Y. (1999) Proc. Natl Acad. Sci. USA, 96, 477-480.
2. Capaldi,A.P., Shastry,M.C., Kleanthous,C., Roder,H. and Radford,S.E. (2001) Nat. Struct. Biol., 8, 68-72.
3. Daggett,V. and Fersht,A.R. (2003) Nat. Rev. Mol. Cell. Biol., 4, 497-502.
4. Dev,K.K. (2004) Nat. Rev. Drug Discov., 3, 1047-1056.
5. Doyle,D.A., Lee,A., Lewis,J., Kim,E., Sheng,M. and MacKinnon,R. (1996) Cell, 85, 1067-1076.
6. Eaton,W.A., Munoz,V., Thompson,P.A., Chan,C.K. and Hofrichter,J. (1997) Curr. Opin. Struct. Biol., 7, 10-14.
7. Fanning,A.S. and Anderson, J.M. (1999) J. Clin. Invest., 103, 767-772.
8. Feng,H., Vu,N.D. and Bai,Y. (2005) J. Mol. Biol., 346, 345-353.
9. Ferguson,N., Capaldi,A.P., James,R., Kleanthous,C. and Radford,S.E. (1999) J. Mol. Biol., 286, 1597-1608.
10. Fersht,A.R. (2004) Proc. Natl Acad. Sci. USA, 101, 14338-14342.
11. Friel,C.T., Capaldi,A.P. and Radford,S.E. (2003) J. Mol. Biol., 326, 293-305.
12. Gianni,S., Travaglini-Allocatelli,C., Cutruzzolà,F., Bigotti,M.G. and Brunori,M. (2001) J. Mol. Biol., 309, 1177-1187.
13. Gianni,S., Guydosh,N.R., Khan,F., Caldas,T.D., Mayor,U., White,G.W., DeMarco,M.L., Daggett,V. and Fersht,A.R. (2003) Proc. Natl Acad. Sci. USA, 100, 13286-13291.
14. Grantcharova,V.P., Riddle,D.S., Santiago,J.V. and Baker,D. (1998) Nat. Struct. Biol., 5, 714-720.
15. Hammond,G.S. (1955) J. Am. Chem. Soc., 77, 334-339.
16. Hedberg,L. and Oliveberg,M. (2004) Proc. Natl Acad. Sci. USA, 101, 7606-7611.
17. Jackson,S.E. and Fersht,A.R. (1991) Biochemistry, 30, 10428-10435.
18. Jemth,P., Gianni,S., Day,R., Li,B., Johnson,C.M., Daggett,V. and Fersht,A.R. (2004) Proc. Natl Acad. Sci. USA, 101, 6450-6455.
19. Khan,F., Chuang,J.I., Gianni,S. and Fersht,A.R. (2003) J. Mol. Biol., 333, 169-186.
20. Khorasanizadeh,S., Peters,I.D. and Roder,H. (1996) Nat. Struct. Biol., 3, 193-205.
21. Kiefhaber,T. (1995) Proc. Natl Acad. Sci. USA, 92, 9029-9033.
22. Kiefhaber,T., Quaas,R., Hahn,U. and Schmid,F.X. (1990) Biochemistry, 29, 3053-3061.
23. Kim,E. and Sheng,M. (2004) Nat. Rev. Neurosci., 5, 771-781.
24. Martinez,J.C., Pisabarro,M.T. and Serrano,L. (1998) Nat. Struct. Biol., 5, 721-729.
25. Matouschek,A., Kellis,J.T.,Jr, Serrano,L., Bycroft,M. and Fersht,A.R. (1990) Nature, 346, 440-445.
26. Matthews,J.M. and Fersht,A.R. (1995) Biochemistry, 34, 6805-6814.
27. Myers,J.K., Pace,C.N. and Scholtz,J.M. (1995) Protein Sci., 4, 2138-2148.
28. Parker,M.J., Spencer,J. and Clarke,A.R. (1995) J. Mol. Biol., 253, 771-786.
29. Riddle,D.S., Grantcharova,V.P., Santiago,J.V., Alm,E., Ruczinski,I. and Baker,D. (1999) J. Mol. Biol., 6, 1016-1024.
30. Sanchez,I.E. and Kiefhaber,T. (2003a) J. Mol. Biol., 325, 367-376.
31. Sanchez,I.E. and Kiefhaber,T. (2003b) J. Mol. Biol., 327, 867-884.
32. Santoro,M.M. and Bolen,D.W. (1988) Biochemistry, 27, 8063-8068.
33. Scott,K.A. and Clarke,J. (2005) Protein Sci., 14, 1617-1629.
34. Scott,K.A., Randles,L.G. and Clarke,J. (2004) J. Mol. Biol., 344, 207-211.
35. Shastry,M.C. and Roder,H. (1998) Nat. Struct. Biol., 5, 385-392.
36. Silow,M. and Oliveberg,M. (1997) Proc. Natl Acad. Sci. USA, 94, 6084-6086.
37. Teilum,K., Maki,K., Kragelund,B.B., Poulsen,F.M. and Roder H. (2002) Proc. Natl Acad. Sci. USA, 99, 9807-9812.
38. Ternstrom,T., Mayor,U., Akke,M. and Oliveberg,M. (1999) Proc. Natl Acad. Sci. USA, 96, 14854-14859.
39. Timasheff,S.N. (1993) Annu. Rev. Biophys. Biomol. Struct., 22, 67-97.
40. Travaglini-Allocatelli,C., Gianni,S., Morea,V., Tramontano,A., Soulimane,T. and Brunori,M. (2003) J. Biol. Chem., 278, 41136-41140.
41. Travaglini-Allocatelli,C., Gianni,S. and Brunori,M. (2004) Trends Biochem. Sci., 29, 535-541.
42. Travaglini-Allocatelli,C., Gianni,S., Dubey,V.K., Borgia,A., Di Matteo,A., Bonivento,D., Cutruzzolà,F., Bren,K.L. and Brunori,M. (2005) J. Biol. Chem., in press.
43. Walma,T., Spronk,C.A., Tessari,M., Aelen,J., Schepens,J., Hendriks,W. and Vuister,G.W. (2002) J. Mol. Biol., 316, 1101-1110.
44. Walma,T., Aelen,J., Nabuurs,S.B., Oostendorp,M., van den Berk,L., Hendriks,W. and Vuister,G.W. (2004) Structure (Camb.), 12, 11-20.
45. Wilken,C., Kitzing,K., Kurzbauer,R., Ehrmann,M. and Clausen,T. (2004) Cell, 117, 483-494.