Early changes in behavior deficits, amyloid β-42 deposits and MAPK activation in doubly transgenic mice co-expressing NSE-controlled human mutant PS2 and APPsw

Cellular and Molecular Neurobiology

Volumn 25, Issue 5, 2005, Pages 881-898

  Hwang, Dae Y ^a   Cho, Jung S ^a   Oh, Jae H ^a   Shim, Sun B ^a   Jee, Seung W ^a   Lee, Su H ^a   Seo, Su J ^a   Song, Chi W ^a   Lee, Seok H ^a   Kim, Yong K ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Alzheimer; APPsw; MAPK; PS2; Transgenic

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; MITOGEN ACTIVATED PROTEIN KINASE;

ALZHEIMER DISEASE; ANIMAL MODEL; ARTICLE; BEHAVIOR; BEHAVIOR DISORDER; BRAIN FUNCTION; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVATION; FEMALE; HUMAN; MALE; MOUSE; MUTANT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MAZE LEARNING; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PEPTIDE FRAGMENTS; PHOSPHOPYRUVATE HYDRATASE; PRESENILIN-2; PROMOTER REGIONS (GENETICS);

MUS MUSCULUS;

EID: 23844522383     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10571-005-4950-x     Document Type: Article

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