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Volumn 275, Issue 36, 2000, Pages 27901-27908

Mutant presenilin 2 transgenic mice: A large increase in the levels of Aβ342 is presumably associated with the low density membrane domain that contains decreased levels of glycerophospholipids and sphingomyelin

(14) Sawamura, Naoya a Morishima Kawashima, Maho a Waki, Hatsue b Kobayashi, Kimio c Kuramochi, Takashi c Frosch, Matthew P d Ding, Kai d Ito, Mamoru c Kim, Tae Wan e Tanzi, Rudolph E e Oyama, Fumitaka a Tabira, Takeshi f Ando, Susumu b Ihara, Yasuo a,g

a UNIVERSITY OF TOKYO (Japan)

b TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY (Japan)

c CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS (Japan)

d BRIGHAM AND WOMEN S HOSPITAL (United States)

e MASSACHUSETTS GENERAL HOSPITAL (United States)

f NATIONAL INSTITUTE OF NEUROSCIENCE (Japan)

g JAPAN SCIENCE AND TECHNOLOGY AGENCY (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCEROPHOSPHOLIPID; MUTANT PROTEIN; PRESENILIN 2; SPHINGOMYELIN;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; GENE MUTATION; GERMANY; HUMAN; MOUSE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN LIPID INTERACTION; TRANSGENIC MOUSE;

AMINO ACID SUBSTITUTION; AMYLOID BETA-PROTEIN; ANIMALS; BRAIN; BRAIN CHEMISTRY; CROSSES, GENETIC; GANGLIOSIDES; GLYCEROPHOSPHOLIPIDS; HETEROZYGOTE; HUMANS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PEPTIDE FRAGMENTS; PRESENILIN-2; SPHINGOMYELINS;

MUS MUSCULUS;

EID: 0034623284 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M004308200 Document Type: Article

Times cited : (79)

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