-
1
-
-
0030293676
-
Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo
-
Borchelt DR, Thinakaran G, Eckman CB, Lee MK, Davenport F, Ratovitsky, Prada CM, Kim G, Seekins S, Yager D, Slunt HH, Wang R, Seeger M, Levey AI, Gandy SE, Copeland NG, Jenkins NA, Price DL, Younkin SG, Sisodia SS (1996) Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo. Neuron 17:1005-1013.
-
(1996)
Neuron
, vol.17
, pp. 1005-1013
-
-
Borchelt, D.R.1
Thinakaran, G.2
Eckman, C.B.3
Lee, M.K.4
Davenport, F.5
Prada, C.M.6
Kim, G.7
Seekins, S.8
Yager, D.9
Slunt, H.H.10
Wang, R.11
Seeger, M.12
Levey, A.I.13
Gandy, S.E.14
Copeland, N.G.15
Jenkins, N.A.16
Price, D.L.17
Younkin, S.G.18
Sisodia, S.S.19
-
2
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
Borchelt DR, Ratovitski T, van Lare J, Lee MK, Gonzales V, Jenkins NA, Copeland NG, Price DL, Sisodia SS (1997) Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron 19:939-945.
-
(1997)
Neuron
, vol.19
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
Van Lare, J.3
Lee, M.K.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Price, D.L.8
Sisodia, S.S.9
-
3
-
-
0017133142
-
Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies
-
Bowen DM, Smith CB, White P, Davison AN (1976) Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies. Brain 99:459-496.
-
(1976)
Brain
, vol.99
, pp. 459-496
-
-
Bowen, D.M.1
Smith, C.B.2
White, P.3
Davison, A.N.4
-
4
-
-
0029686696
-
Evolution of the neuropathology of Alzheimer's disease
-
Braak H, Braak E (1996) Evolution of the neuropathology of Alzheimer's disease. Acta Neurol Scand [Suppl]. 165:3-12.
-
(1996)
Acta Neurol Scand [Suppl].
, vol.165
, pp. 3-12
-
-
Braak, H.1
Braak, E.2
-
5
-
-
0027490614
-
Staging of Alzheimer-related cortical destruction
-
Braak H, Braak E, Bohl J (1993) Staging of Alzheimer-related cortical destruction. Eur Neurol 33:403-408.
-
(1993)
Eur Neurol
, vol.33
, pp. 403-408
-
-
Braak, H.1
Braak, E.2
Bohl, J.3
-
6
-
-
0002988098
-
Histochemical distribution of acetylcholinesterase in the central nervous system: Clues to the localization of cholinergic neurons
-
Bjorklund A, Hokfelt T, Kuhar MJ, eds, Amsterdam: Elsevier Science
-
Butcher LL, Woolf NJ (1984) Histochemical distribution of acetylcholinesterase in the central nervous system: clues to the localization of cholinergic neurons. In: Classical transmitters and transmitter receptors in the CNS Part II (Bjorklund A, Hokfelt T, Kuhar MJ, eds), pp 1-50. Amsterdam: Elsevier Science.
-
(1984)
Classical Transmitters and Transmitter Receptors in the CNS
, Issue.PART II
, pp. 1-50
-
-
Butcher, L.L.1
Woolf, N.J.2
-
7
-
-
0027526419
-
Release of excess amyloid beta protein from a mutant amyloid beta protein precursor
-
Cai XD, Golde TE, Younkin SG (1993) Release of excess amyloid beta protein from a mutant amyloid beta protein precursor. Science 259:514-516.
-
(1993)
Science
, vol.259
, pp. 514-516
-
-
Cai, X.D.1
Golde, T.E.2
Younkin, S.G.3
-
8
-
-
0032558784
-
Neuron loss in APP transgenic mice
-
Calhoun ME, Wiederhold KH, Abramowski D, Phinney AL, Probst A, Sturchler-Pierrat C, Staufenbiel M, Sommer B, Jucker M (1998) Neuron loss in APP transgenic mice. Nature 395:755-756.
-
(1998)
Nature
, vol.395
, pp. 755-756
-
-
Calhoun, M.E.1
Wiederhold, K.H.2
Abramowski, D.3
Phinney, A.L.4
Probst, A.5
Sturchler-Pierrat, C.6
Staufenbiel, M.7
Sommer, B.8
Jucker, M.9
-
9
-
-
0026745610
-
Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production
-
Citron M, Oltersdorf T, Haass C, McConlogue L, Hung AY, Seubert P, Vigo-Pelfrey C, Lieberburg I, Selkoe DJ (1992) Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production. Nature 360:672-674.
-
(1992)
Nature
, vol.360
, pp. 672-674
-
-
Citron, M.1
Oltersdorf, T.2
Haass, C.3
McConlogue, L.4
Hung, A.Y.5
Seubert, P.6
Vigo-Pelfrey, C.7
Lieberburg, I.8
Selkoe, D.J.9
-
10
-
-
16944362157
-
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice
-
Citron M, Westaway D, Xia W, Carlson G, Diehl T, Levesque G, Johnson-Wood K, Lee M, Seubert P, Davis A, Kholodenko D, Motter R, Sherrington R, Perry B, Yao H, Strome R, Lieberburg I, Rommens J, Kim S, Schenk D, Fraser P, St George H, Selkoe DJ (1997) Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice. Nature Med 3:67-72.
-
(1997)
Nature Med
, vol.3
, pp. 67-72
-
-
Citron, M.1
Westaway, D.2
Xia, W.3
Carlson, G.4
Diehl, T.5
Levesque, G.6
Johnson-Wood, K.7
Lee, M.8
Seubert, P.9
Davis, A.10
Kholodenko, D.11
Motter, R.12
Sherrington, R.13
Perry, B.14
Yao, H.15
Strome, R.16
Lieberburg, I.17
Rommens, J.18
Kim, S.19
Schenk, D.20
Fraser, P.21
St George, H.22
Selkoe, D.J.23
more..
-
11
-
-
0022875838
-
Cholinergic function and intellectual decline in Alzheimer's disease
-
Collerton D (1986) Cholinergic function and intellectual decline in Alzheimer's disease. Neuroscicnce 19:1-28.
-
(1986)
Neuroscicnce
, vol.19
, pp. 1-28
-
-
Collerton, D.1
-
12
-
-
0003098752
-
Current protocols for light microscopy immunocytochemistry
-
Cuello AC, ed, West Sussex: Wiley
-
Côté SL, Ribeiro-da-Silva A, Cuello AC (1993) Current protocols for light microscopy immunocytochemistry. In: Immunohistochemistry II (Cuello AC, ed), pp 147-168. West Sussex: Wiley.
-
(1993)
Immunohistochemistry
, vol.2
, pp. 147-168
-
-
Côté, S.L.1
Ribeiro-da-Silva, A.2
Cuello, A.C.3
-
13
-
-
0021367326
-
The anatomy of the CNS cholinergic neurons
-
Cuello AC, Sofroniew MV (1984) The anatomy of the CNS cholinergic neurons. Trends Neurosci 7:74-78.
-
(1984)
Trends Neurosci
, vol.7
, pp. 74-78
-
-
Cuello, A.C.1
Sofroniew, M.V.2
-
14
-
-
0021355249
-
Development and application of a monoclonal rat peroxidase antiperoxidase (PAP) immunocytochemical reagent
-
Cuello AC, Milstein C, Wright B, Bramwell S, Priestley JV, Jarvis J (1984) Development and application of a monoclonal rat peroxidase antiperoxidase (PAP) immunocytochemical reagent. Histochemistry 80:257-261.
-
(1984)
Histochemistry
, vol.80
, pp. 257-261
-
-
Cuello, A.C.1
Milstein, C.2
Wright, B.3
Bramwell, S.4
Priestley, J.V.5
Jarvis, J.6
-
15
-
-
0011162190
-
Selective loss of central cholinergic neurons in Alzheimer's disease
-
Davies P, Maloney AJ (1976) Selective loss of central cholinergic neurons in Alzheimer's disease. Lancet 2:1403.
-
(1976)
Lancet
, vol.2
, pp. 1403
-
-
Davies, P.1
Maloney, A.J.2
-
16
-
-
0032032019
-
An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos
-
Davis JA, Naruse S, Chen H, Eckman C, Younkin S, Price DL, Borchelt DR, Sisodia SS, Wong PC (1998) An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos. Neuron 20:603-609.
-
(1998)
Neuron
, vol.20
, pp. 603-609
-
-
Davis, J.A.1
Naruse, S.2
Chen, H.3
Eckman, C.4
Younkin, S.5
Price, D.L.6
Borchelt, D.R.7
Sisodia, S.S.8
Wong, P.C.9
-
17
-
-
0032105348
-
TrkA antagonists decrease NGF-induced ChAT activity in vitro and modulate cholinergic synaptic number in vivo
-
Debeir T, Saragovi HU, Cuello AC (1998) TrkA antagonists decrease NGF-induced ChAT activity in vitro and modulate cholinergic synaptic number in vivo. J Physiol (Paris) 92:205-208.
-
(1998)
J Physiol (Paris)
, vol.92
, pp. 205-208
-
-
Debeir, T.1
Saragovi, H.U.2
Cuello, A.C.3
-
18
-
-
0026440987
-
Cortical biopsy in Alzheimer's disease: Diagnostic accuracy and neurochemical, neuropathological, and cognitive correlations
-
Intraventricular Bethanecol Study Group
-
DeKosky ST, Harbaugh RE, Schmitt FA, Bakay RA, Chui HC, Knopman DS, Reeder TM, Shetter AG, Senter HJ, Markesbery WR (1992) Cortical biopsy in Alzheimer's disease: diagnostic accuracy and neurochemical, neuropathological, and cognitive correlations. Intraventricular Bethanecol Study Group. Ann Neurol 32:625-632.
-
(1992)
Ann Neurol
, vol.32
, pp. 625-632
-
-
DeKosky, S.T.1
Harbaugh, R.E.2
Schmitt, F.A.3
Bakay, R.A.4
Chui, H.C.5
Knopman, D.S.6
Reeder, T.M.7
Shetter, A.G.8
Senter, H.J.9
Markesbery, W.R.10
-
19
-
-
0021970688
-
Laminar organization of cholinergic circuits in human frontal cortex in Alzheimer's disease and aging
-
DeKosky ST, Scheff SW, Markesbery WR (1985) Laminar organization of cholinergic circuits in human frontal cortex in Alzheimer's disease and aging. Neurology 35:1425-1431.
-
(1985)
Neurology
, vol.35
, pp. 1425-1431
-
-
DeKosky, S.T.1
Scheff, S.W.2
Markesbery, W.R.3
-
20
-
-
16044366039
-
Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1
-
Duff K, Eckman C, Zehr C, Yu X, Prada CM, Perez-tur J, Hutton M, Buee L, Harigaya Y, Yager D, Morgan D, Gordon MN, Holcomb L, Refolo, Zenk B, Hardy J, Younkin S (1996) Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1. Nature 383:710-713.
-
(1996)
Nature
, vol.383
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
Yu, X.4
Prada, C.M.5
Perez-tur, J.6
Hutton, M.7
Buee, L.8
Harigaya, Y.9
Yager, D.10
Morgan, D.11
Gordon, M.N.12
Holcomb, L.13
Refolo14
Zenk, B.15
Hardy, J.16
Younkin, S.17
-
21
-
-
0030840637
-
Mechanisms controlling neuronal plasticity in somatosensory cortex
-
Dykes RW (1997) Mechanisms controlling neuronal plasticity in somatosensory cortex. Can J Physiol Pharmacol 75:535-545.
-
(1997)
Can J Physiol Pharmacol
, vol.75
, pp. 535-545
-
-
Dykes, R.W.1
-
23
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing v717f beta-amyloid precursor protein
-
Games D, Adams D, Alessandrini R, Barbour R, Berthelette P, Blackwell C, Carr T, Clemens J, Donaldson T, Gillespie F, Guido T, Hagoplan S, Johnson-Wood K, Khan K, Lee M, Leibowitz P, Lieberburg I, Little S, Masliah E, McConlogue L, Montoya-Zavala M, Mucke L, Paganini L, Penniman E, Power M, Schenk D, Seubert P, Snyder B, Soriano F, Tan H, Vitale J, Wadsworth S, Wolozin B, Zhao J (1995) Alzheimer-type neuropathology in transgenic mice overexpressing v717f beta-amyloid precursor protein. Nature 373:523-527.
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
Carr, T.7
Clemens, J.8
Donaldson, T.9
Gillespie, F.10
Guido, T.11
Hagoplan, S.12
Johnson-Wood, K.13
Khan, K.14
Lee, M.15
Leibowitz, P.16
Lieberburg, I.17
Little, S.18
Masliah, E.19
McConlogue, L.20
Montoya-Zavala, M.21
Mucke, L.22
Paganini, L.23
Penniman, E.24
Power, M.25
Schenk, D.26
Seubert, P.27
Snyder, B.28
Soriano, F.29
Tan, H.30
Vitale, J.31
Wadsworth, S.32
Wolozin, B.33
Zhao, J.34
more..
-
24
-
-
0028204470
-
Nerve growth factor and the monosialoganglioside GM1: Analogous and different in vivo effects on biochemical, morphological, and behavioral parameters of adult cortically lesioned rats
-
Garofalo L, Cuello AC (1994) Nerve growth factor and the monosialoganglioside GM1: analogous and different in vivo effects on biochemical, morphological, and behavioral parameters of adult cortically lesioned rats. Exp Neurol 125:195-217.
-
(1994)
Exp Neurol
, vol.125
, pp. 195-217
-
-
Garofalo, L.1
Cuello, A.C.2
-
25
-
-
0026552615
-
Nerve growth factor-induced synaptogenesis and hypertrophy of cortical cholinergic terminals
-
Garofalo L, Ribeiro-da-Silva A, Cuello AC (1992) Nerve growth factor-induced synaptogenesis and hypertrophy of cortical cholinergic terminals. Proc Natl Acad Sci USA 89:2639-2643.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 2639-2643
-
-
Garofalo, L.1
Ribeiro-da-Silva, A.2
Cuello, A.C.3
-
26
-
-
0030009912
-
Expression of the putative vesicular acetylcholine transporter in rat brain and localization in cholinergic synaptic vesicles
-
Gilmor ML, Nash NR, Roghani A, Edwards RH, Yi H, Hersch SM, Levey AI (1996) Expression of the putative vesicular acetylcholine transporter in rat brain and localization in cholinergic synaptic vesicles. J Neurosci 16:2179-2190.
-
(1996)
J Neurosci
, vol.16
, pp. 2179-2190
-
-
Gilmor, M.L.1
Nash, N.R.2
Roghani, A.3
Edwards, R.H.4
Yi, H.5
Hersch, S.M.6
Levey, A.I.7
-
27
-
-
0344936307
-
Ultrastructural localization of amyloid beta protein in transfected embryonal carcinoma (P19) cells after neuroectodermal differentiation
-
Grant SM, Szyf M, Cuello AC (1997) Ultrastructural localization of amyloid beta protein in transfected embryonal carcinoma (P19) cells after neuroectodermal differentiation. Soc Neurosci Abstr 23:540.
-
(1997)
Soc Neurosci Abstr
, vol.23
, pp. 540
-
-
Grant, S.M.1
Szyf, M.2
Cuello, A.C.3
-
28
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
-
Holcomb L, Gordon MN, McGowan E, Yu X, Benkovic S, Jantzen P, Wright, Saad I, Mueller R, Morgan D, Sanders S, Zehr C, O'Campo K, Hardy, Prada CM, Eckman C, Younkin S, Hsiao K, Duff K (1998) Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nature Med 4:97-100.
-
(1998)
Nature Med
, vol.4
, pp. 97-100
-
-
Holcomb, L.1
Gordon, M.N.2
McGowan, E.3
Yu, X.4
Benkovic, S.5
Jantzen, P.6
Wright7
Saad, I.8
Mueller, R.9
Morgan, D.10
Sanders, S.11
Zehr, C.12
O'Campo, K.13
Hardy14
Prada, C.M.15
Eckman, C.16
Younkin, S.17
Hsiao, K.18
Duff, K.19
-
29
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, Yang F, Cole G (1996) Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274:99-102.
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
30
-
-
0029849644
-
Full-length amyloid-beta (1-42(43)) and amino-terminally modified and truncated amyloid-beta 42(43) deposit in diffuse plaques
-
Iwatsubo T, Saido TC, Mann DM, Lee VM, Trojanowski JQ (1996) Full-length amyloid-beta (1-42(43)) and amino-terminally modified and truncated amyloid-beta 42(43) deposit in diffuse plaques. Am J Pathol 149:1823-1830.
-
(1996)
Am J Pathol
, vol.149
, pp. 1823-1830
-
-
Iwatsubo, T.1
Saido, T.C.2
Mann, D.M.3
Lee, V.M.4
Trojanowski, J.Q.5
-
31
-
-
0025969693
-
Cholinergic depletion prevents expansion of topographic maps in somatosensory cortex
-
Juliano SL, Ma W, Eslin D (1991) Cholinergic depletion prevents expansion of topographic maps in somatosensory cortex. Proc Natl Acad Sci USA 88:780-784.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 780-784
-
-
Juliano, S.L.1
Ma, W.2
Eslin, D.3
-
32
-
-
0029996479
-
Beta-amyloid-related peptides inhibit potassium-evoked acetylcholine release from rat hippocampal slices
-
Kar S, Seto D, Gaudreau P, Quirion R (1996) Beta-amyloid-related peptides inhibit potassium-evoked acetylcholine release from rat hippocampal slices. J Neurosci 16:1034-1040.
-
(1996)
J Neurosci
, vol.16
, pp. 1034-1040
-
-
Kar, S.1
Seto, D.2
Gaudreau, P.3
Quirion, R.4
-
33
-
-
0022616654
-
Alzheimer's disease
-
Katzman R (1986) Alzheimer's disease. N Engl J Med 314:964-973.
-
(1986)
N Engl J Med
, vol.314
, pp. 964-973
-
-
Katzman, R.1
-
34
-
-
0032513387
-
Cortical map reorganization enabled by nucleus basalis activity
-
Kilgard MP, Merzenich MM (1998) Cortical map reorganization enabled by nucleus basalis activity. Science 279:1714-1718.
-
(1998)
Science
, vol.279
, pp. 1714-1718
-
-
Kilgard, M.P.1
Merzenich, M.M.2
-
35
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
Levy-Lahad E, Wasco W, Poorkaj P, Romano DM, Oshima J, Pettingell WH, Yu CE, Jondro PD, Schmidt SD, Wang K (1995) Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 269:973-977.
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
Romano, D.M.4
Oshima, J.5
Pettingell, W.H.6
Yu, C.E.7
Jondro, P.D.8
Schmidt, S.D.9
Wang, K.10
-
36
-
-
0024548786
-
An atlas of the regional and laminar distribution of choline acetyltransferase immuno-reactivity in rat cerebral cortex
-
Lysakowski A, Wainer BH, Bruce G, Hersh LB (1989) An atlas of the regional and laminar distribution of choline acetyltransferase immuno-reactivity in rat cerebral cortex. Neuroscience 28:291-336.
-
(1989)
Neuroscience
, vol.28
, pp. 291-336
-
-
Lysakowski, A.1
Wainer, B.H.2
Bruce, G.3
Hersh, L.B.4
-
37
-
-
0029813177
-
Comparison of neurodegenerative pathology in transgenic mice over-expressing v717f beta-amyloid precursor protein and Alzheimer's disease
-
Masliah E, Sisk A, Mallory M, Mucke L, Schenk D, Games D (1996) Comparison of neurodegenerative pathology in transgenic mice over-expressing v717f beta-amyloid precursor protein and Alzheimer's disease. J Neurosci 16:5795-5811.
-
(1996)
J Neurosci
, vol.16
, pp. 5795-5811
-
-
Masliah, E.1
Sisk, A.2
Mallory, M.3
Mucke, L.4
Schenk, D.5
Games, D.6
-
38
-
-
0032886415
-
Abnormal pathology development in transgenic mice over-expressing both mutant amyloid recursor protein and mutant presenilin-1 transgenes
-
in press
-
McGowan E, Sanders S, Iwatsubo T, Takeuchi A, Saido T, Zehr C, Yu X, Uljon SE, Wang R, Hsiao K, Mann D, Dickson D, Duff K (1999) Abnormal pathology development in transgenic mice over-expressing both mutant amyloid recursor protein and mutant presenilin-1 transgenes. Neurobiol Dis, in press.
-
(1999)
Neurobiol Dis
-
-
McGowan, E.1
Sanders, S.2
Iwatsubo, T.3
Takeuchi, A.4
Saido, T.5
Zehr, C.6
Yu, X.7
Uljon, S.E.8
Wang, R.9
Hsiao, K.10
Mann, D.11
Dickson, D.12
Duff, K.13
-
39
-
-
0022632276
-
Systematic regional differences in the cholinergic innervation of the primate cerebral cortex: Distribution of enzyme activities and some behavioral implications
-
Mesulam MM, Volicer L, Marquis JK, Mufson EJ, Green RC (1986) Systematic regional differences in the cholinergic innervation of the primate cerebral cortex: distribution of enzyme activities and some behavioral implications. Ann Neurol 19:144-151.
-
(1986)
Ann Neurol
, vol.19
, pp. 144-151
-
-
Mesulam, M.M.1
Volicer, L.2
Marquis, J.K.3
Mufson, E.J.4
Green, R.C.5
-
40
-
-
0027970897
-
Synaptotrophic effects of human amyloid beta protein precursors in the cortex of transgenic mice
-
Mucke L, Masliah E, Johnson WB, Ruppe MD, Alford M, Rockenstein EM, Forss-Petter S, Pietropaolo M, Mallory M, Abraham CR (1994) Synaptotrophic effects of human amyloid beta protein precursors in the cortex of transgenic mice. Brain Res 666:151-167.
-
(1994)
Brain Res
, vol.666
, pp. 151-167
-
-
Mucke, L.1
Masliah, E.2
Johnson, W.B.3
Ruppe, M.D.4
Alford, M.5
Rockenstein, E.M.6
Forss-Petter, S.7
Pietropaolo, M.8
Mallory, M.9
Abraham, C.R.10
-
41
-
-
0030978998
-
Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein
-
Nalbantoglu J, Tirado-Santiago G, Lahsaini A, Poirier J, Goncalves O, Verge G, Momoli F, Welner SA, Massicotte G, Julien JP, Shapiro ML (1997) Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein. Nature 387:500-505.
-
(1997)
Nature
, vol.387
, pp. 500-505
-
-
Nalbantoglu, J.1
Tirado-Santiago, G.2
Lahsaini, A.3
Poirier, J.4
Goncalves, O.5
Verge, G.6
Momoli, F.7
Welner, S.A.8
Massicotte, G.9
Julien, J.P.10
Shapiro, M.L.11
-
42
-
-
0021059767
-
Persistence of cholinergic neurons in the basal nucleus in a brain with senile dementia of the Alzheimer's type demonstrated by immunohistochemical staining for choline acetyltransferase
-
Pearson RC, Sofroniew MV, Cuello AC, Powell TP, Eckenstein F, Esiri MM, Wilcock GK (1983) Persistence of cholinergic neurons in the basal nucleus in a brain with senile dementia of the Alzheimer's type demonstrated by immunohistochemical staining for choline acetyltransferase. Brain Res 289:375-379.
-
(1983)
Brain Res
, vol.289
, pp. 375-379
-
-
Pearson, R.C.1
Sofroniew, M.V.2
Cuello, A.C.3
Powell, T.P.4
Eckenstein, F.5
Esiri, M.M.6
Wilcock, G.K.7
-
43
-
-
0018078940
-
Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia
-
Perry EK, Tomlinson BE, Blessed G, Bergmann K, Gibson PH, Perry RH (1978) Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia. Br Med J 2:1457-1459.
-
(1978)
Br Med J
, vol.2
, pp. 1457-1459
-
-
Perry, E.K.1
Tomlinson, B.E.2
Blessed, G.3
Bergmann, K.4
Gibson, P.H.5
Perry, R.H.6
-
44
-
-
0021333044
-
Intralaminar neurochemical distributions in human midtemporal cortex: Comparison between Alzheimer's disease and the normal
-
Perry EK, Atack JR, Perry RH, Hardy JA, Dodd PR, Edwardson JA, Blessed G, Tomlinson BE, Fairbairn AF (1984) Intralaminar neurochemical distributions in human midtemporal cortex: comparison between Alzheimer's disease and the normal. J Neurochem 42:1402-1410.
-
(1984)
J Neurochem
, vol.42
, pp. 1402-1410
-
-
Perry, E.K.1
Atack, J.R.2
Perry, R.H.3
Hardy, J.A.4
Dodd, P.R.5
Edwardson, J.A.6
Blessed, G.7
Tomlinson, B.E.8
Fairbairn, A.F.9
-
45
-
-
0031921466
-
Mutant genes in familial Alzheimer's-disease and transgenic models
-
Price DL, Sisodia SS (1998) Mutant genes in familial Alzheimer's-disease and transgenic models. Annu Rev Neurosci 21:479-505.
-
(1998)
Annu Rev Neurosci
, vol.21
, pp. 479-505
-
-
Price, D.L.1
Sisodia, S.S.2
-
46
-
-
0032032847
-
Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression
-
Qian S, Jiang P, Guan XM, Singh G, Trumbauer ME, Yu H, Chen HY, Van der Ploeg LH, de Ploeg LH, Zheng H (1998) Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression. Neuron 20:611-617.
-
(1998)
Neuron
, vol.20
, pp. 611-617
-
-
Qian, S.1
Jiang, P.2
Guan, X.M.3
Singh, G.4
Trumbauer, M.E.5
Yu, H.6
Chen, H.Y.7
Van Der Ploeg, L.H.8
De Ploeg, L.H.9
Zheng, H.10
-
47
-
-
0031816059
-
Role of the basal forebrain cholinergic projection in somatosensory cortical plasticity
-
Sachdev RN, Lu SM, Wiley RG, Ebner FF (1998) Role of the basal forebrain cholinergic projection in somatosensory cortical plasticity, J Neurophysiol 79:3216-3228.
-
(1998)
J Neurophysiol
, vol.79
, pp. 3216-3228
-
-
Sachdev, R.N.1
Lu, S.M.2
Wiley, R.G.3
Ebner, F.F.4
-
48
-
-
16044373524
-
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
Scheuner D, Eckman C, Jensen M, Song X, Citron M, Suzuki N, Bird TD, Hardy J, Hutton M, Kukull W, Larson E, Levy-Lahad E, Viitanen M, Peskind E, Poorkaj P, Schellenberg G, Tanzi R, Wasco W, Lannfelt L, Selkoe D, Younkin S (1996) Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nature Med 2:864-870.
-
(1996)
Nature Med
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
Bird, T.D.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
Larson, E.11
Levy-Lahad, E.12
Viitanen, M.13
Peskind, E.14
Poorkaj, P.15
Schellenberg, G.16
Tanzi, R.17
Wasco, W.18
Lannfelt, L.19
Selkoe, D.20
Younkin, S.21
more..
-
49
-
-
0028171885
-
Amyloid beta-protein precursor: New clues to the genesis of Alzheimer's disease
-
Selkoe DJ (1994) Amyloid beta-protein precursor: new clues to the genesis of Alzheimer's disease. Curr Opin Neurobiol 4:708-716.
-
(1994)
Curr Opin Neurobiol
, vol.4
, pp. 708-716
-
-
Selkoe, D.J.1
-
50
-
-
0022365676
-
Development of a mouse antiperoxidase secreting hybridoma for use in the production of a mouse PAP complex for immunocytochemistry and as a parent cell line in the development of hybrid hybridomas
-
Semenenko FM, Bramwell S, Sidebottom E, Cuello AC (1985) Development of a mouse antiperoxidase secreting hybridoma for use in the production of a mouse PAP complex for immunocytochemistry and as a parent cell line in the development of hybrid hybridomas. Histochemistry 83:405-408.
-
(1985)
Histochemistry
, vol.83
, pp. 405-408
-
-
Semenenko, F.M.1
Bramwell, S.2
Sidebottom, E.3
Cuello, A.C.4
-
51
-
-
0030779784
-
Skeletal and CNS defects in Presenilin-1-deficient mice
-
Shen J, Bronson RT, Chen DF, Xia W, Selkoe DJ, Tonegawa S (1997) Skeletal and CNS defects in Presenilin-1-deficient mice. Cell 89:629-639.
-
(1997)
Cell
, vol.89
, pp. 629-639
-
-
Shen, J.1
Bronson, R.T.2
Chen, D.F.3
Xia, W.4
Selkoe, D.J.5
Tonegawa, S.6
-
52
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M, Chi H, Lin C, Li G, Holman K (1995) Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 375:754-760.
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
Chi, H.7
Lin, C.8
Li, G.9
Holman, K.10
-
53
-
-
0021055988
-
Retrograde changes in cholinergic neurons in the basal forebrain of the rat following cortical damage
-
Sofroniew MV, Pearson RC, Eckenstein F, Cuello AC, Powell TP (1983) Retrograde changes in cholinergic neurons in the basal forebrain of the rat following cortical damage. Brain Res 289:370-374.
-
(1983)
Brain Res
, vol.289
, pp. 370-374
-
-
Sofroniew, M.V.1
Pearson, R.C.2
Eckenstein, F.3
Cuello, A.C.4
Powell, T.P.5
-
54
-
-
0011444914
-
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
-
Sturchler-Pierrat C, Abramowski D, Duke M, Wiederhold KH, Mistl C, Rothacher S, Ledermann B, Burki K, Frey P, Paganetti PA, Waridel C, Calhoun ME, Jucker M, Probst A, Staufenbiel M, Sommer B (1997) Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. Proc Natl Acad Sci USA 94:13287-13292.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 13287-13292
-
-
Sturchler-Pierrat, C.1
Abramowski, D.2
Duke, M.3
Wiederhold, K.H.4
Mistl, C.5
Rothacher, S.6
Ledermann, B.7
Burki, K.8
Frey, P.9
Paganetti, P.A.10
Waridel, C.11
Calhoun, M.E.12
Jucker, M.13
Probst, A.14
Staufenbiel, M.15
Sommer, B.16
-
55
-
-
0028322017
-
An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants
-
Suzuki N, Cheung TT, Cai XD, Odaka A, Otvos LJ, Eckman C, Golde TE, Younkin SG (1994) An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. Science 264:1336-1340.
-
(1994)
Science
, vol.264
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, X.D.3
Odaka, A.4
Otvos, L.J.5
Eckman, C.6
Golde, T.E.7
Younkin, S.G.8
-
56
-
-
0030782198
-
Effects of muscarinic blockade in perirhinal cortex during visual recognition
-
Tang Y, Mishkin M, Aigner TG (1997) Effects of muscarinic blockade in perirhinal cortex during visual recognition. Proc Natl Acad Sci USA 94:12667-12669.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 12667-12669
-
-
Tang, Y.1
Mishkin, M.2
Aigner, T.G.3
-
57
-
-
0020072221
-
Alzheimer's disease and senile dementia: Loss of neurons in the basal forebrain
-
Whitehouse PJ, Price DL, Struble RG, Clark AW, Coyle JT, Delon MR (1982) Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain. Science 215:1237-1239.
-
(1982)
Science
, vol.215
, pp. 1237-1239
-
-
Whitehouse, P.J.1
Price, D.L.2
Struble, R.G.3
Clark, A.W.4
Coyle, J.T.5
Delon, M.R.6
-
58
-
-
0029152729
-
Essential role of neocortical acetylcholine in spatial memory
-
Winkler J, Suhr ST, Gage FH, Thal LJ, Fisher LJ (1995) Essential role of neocortical acetylcholine in spatial memory. Nature 375:484-487.
-
(1995)
Nature
, vol.375
, pp. 484-487
-
-
Winkler, J.1
Suhr, S.T.2
Gage, F.H.3
Thal, L.J.4
Fisher, L.J.5
-
59
-
-
17744401440
-
Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm
-
Wong PC, Zheng H, Chen H, Becher MW, Sirinathsinghji DJ, Trumbauer ME, Chen HY, Price DL, Van der Ploeg LH, Sisodia SS (1997) Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm. Nature 387:288-292.
-
(1997)
Nature
, vol.387
, pp. 288-292
-
-
Wong, P.C.1
Zheng, H.2
Chen, H.3
Becher, M.W.4
Sirinathsinghji, D.J.5
Trumbauer, M.E.6
Chen, H.Y.7
Price, D.L.8
Van Der Ploeg, L.H.9
Sisodia, S.S.10
-
60
-
-
0031937121
-
Synaptic numbers across cortical laminae and cognitive performance of the rat during ageing
-
Wong TP, Campbell PM, Ribeiro-da-Silva A, Cuello AC (1998) Synaptic numbers across cortical laminae and cognitive performance of the rat during ageing. Neuroscience 84:403-412.
-
(1998)
Neuroscience
, vol.84
, pp. 403-412
-
-
Wong, T.P.1
Campbell, P.M.2
Ribeiro-da-Silva, A.3
Cuello, A.C.4
|