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Volumn 6, Issue 5, 2004, Pages

Direct Toll-like receptor 2 mediated co-stimulation of T cells in the mouse system as a basis for chronic inflammatory joint disease

Author keywords

co stimulation; lipoproteins; rheumatoid arthritis; T lymphocytes; Toll like receptor

Indexed keywords

BACTERIAL VACCINE; CELL SURFACE RECEPTOR; GAMMA INTERFERON; LIPOPROTEIN; MEMBRANE ANTIGEN; MEMBRANE PROTEIN; OUTER MEMBRANE PROTEIN; OUTER SURFACE PROTEIN A; RECOMBINANT PROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2;

EID: 23844480624     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar1212     Document Type: Article
Times cited : (76)

References (81)
  • 1
    • 0034980187 scopus 로고    scopus 로고
    • Autoimmune mechanisms in antibiotic treatment-resistant lyme arthritis
    • COI: 1:STN:280:DC%2BD3M3jvFKmsg%3D%3D, PID: 11334491
    • Steere AC, Gross D, Meyer AL, Huber BT: Autoimmune mechanisms in antibiotic treatment-resistant lyme arthritis. J Autoimmun. 2001, 16: 263-268. 10.1006/jaut.2000.0495. DOI: 10.1006/jaut.2000.0495
    • (2001) J Autoimmun , vol.16 , pp. 263-268
    • Steere, A.C.1    Gross, D.2    Meyer, A.L.3    Huber, B.T.4
  • 2
    • 0038011833 scopus 로고    scopus 로고
    • Evolving concepts of rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BD3sXjs1ynu7c%3D, PID: 12748655
    • Firestein GS: Evolving concepts of rheumatoid arthritis. Nature. 2003, 423: 356-361. 10.1038/nature01661. DOI: 10.1038/nature01661
    • (2003) Nature , vol.423 , pp. 356-361
    • Firestein, G.S.1
  • 3
    • 0037334151 scopus 로고    scopus 로고
    • Does activation of the innate immune system contribute to the development of rheumatoid arthritis?
    • PID: 12632408
    • Klinman D: Does activation of the innate immune system contribute to the development of rheumatoid arthritis?. Arthritis Rheum. 2003, 48: 590-593. 10.1002/art.10852. DOI: 10.1002/art.10852
    • (2003) Arthritis Rheum , vol.48 , pp. 590-593
    • Klinman, D.1
  • 4
    • 0002939077 scopus 로고    scopus 로고
    • Rheumatoid Arthritis
    • Silman AJ, Hochberg MC, (eds), Oxford University Press, Oxford
    • Silman AJ, Hochberg MC: Rheumatoid Arthritis. In Epidemiology of the Rheumatic Diseases. Edited by: Silman AJ, Hochberg MC. 2001, Oxford: Oxford University Press, 31-71.
    • (2001) In Epidemiology of the Rheumatic Diseases , pp. 31-71
    • Silman, A.J.1    Hochberg, M.C.2
  • 5
    • 0033198204 scopus 로고    scopus 로고
    • Cutting edge: inflammatory signaling by Borrelia burgdorferilipoproteins is mediated by toll-like receptor 2
    • COI: 1:CAS:528:DyaK1MXls1Krs78%3D, PID: 10452971
    • Hirschfeld M, Kirschning CJ, Schwandner R, Wesche H, Weis JH, Wooten RM, Weis JJ: Cutting edge: inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2. J Immunol. 1999, 163: 2382-2386.
    • (1999) J Immunol , vol.163 , pp. 2382-2386
    • Hirschfeld, M.1    Kirschning, C.J.2    Schwandner, R.3    Wesche, H.4    Weis, J.H.5    Wooten, R.M.6    Weis, J.J.7
  • 6
    • 0034210449 scopus 로고    scopus 로고
    • How does the immune system distinguish self from nonself?
    • COI: 1:CAS:528:DC%2BD3cXltVCit7k%3D, PID: 10910738, discussion 257–344
    • Medzhitov R, Janeway CA: How does the immune system distinguish self from nonself?. Semin Immunol. 2000, 12: 185-188. 10.1006/smim.2000.0230. discussion 257–344 DOI: 10.1006/smim.2000.0230
    • (2000) Semin Immunol , vol.12 , pp. 185-188
    • Medzhitov, R.1    Janeway, C.A.2
  • 7
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • COI: 1:CAS:528:DC%2BD38XlvF2qu74%3D, PID: 11905821
    • Medzhitov R: Toll-like receptors and innate immunity. Nat Rev Immunol. 2001, 1: 135-145. 10.1038/35100529. DOI: 10.1038/35100529
    • (2001) Nat Rev Immunol , vol.1 , pp. 135-145
    • Medzhitov, R.1
  • 8
    • 0012929728 scopus 로고    scopus 로고
    • Toll-like receptors
    • COI: 1:CAS:528:DC%2BD3sXjtF2isrg%3D, PID: 12524386
    • Takeda K, Kaisho T, Akira S: Toll-like receptors. Annu Rev Immunol. 2003, 21: 335-376. 10.1146/annurev.immunol.21.120601.141126. DOI: 10.1146/annurev.immunol.21.120601.141126
    • (2003) Annu Rev Immunol , vol.21 , pp. 335-376
    • Takeda, K.1    Kaisho, T.2    Akira, S.3
  • 9
    • 0034651637 scopus 로고    scopus 로고
    • Gene expressions of lipopolysaccharide receptors, toll-like receptors 2 and 4, are differently regulated in mouse T lymphocytes
    • COI: 1:CAS:528:DC%2BD3cXhtFKitL8%3D, PID: 10666214
    • Matsuguchi T, Takagi K, Musikacharoen T, Yoshikai Y: Gene expressions of lipopolysaccharide receptors, toll-like receptors 2 and 4, are differently regulated in mouse T lymphocytes. Blood. 2000, 95: 1378-1385.
    • (2000) Blood , vol.95 , pp. 1378-1385
    • Matsuguchi, T.1    Takagi, K.2    Musikacharoen, T.3    Yoshikai, Y.4
  • 10
    • 0036570169 scopus 로고    scopus 로고
    • Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
    • COI: 1:CAS:528:DC%2BD38Xjt12jt7k%3D, PID: 11970999
    • Hornung V, Rothenfusser S, Britsch S, Krug A, Jahrsdorfer B, Giese T, Endres S, Hartmann G: Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol. 2002, 168: 4531-4537. DOI: 10.4049/jimmunol.168.9.4531
    • (2002) J Immunol , vol.168 , pp. 4531-4537
    • Hornung, V.1    Rothenfusser, S.2    Britsch, S.3    Krug, A.4    Jahrsdorfer, B.5    Giese, T.6    Endres, S.7    Hartmann, G.8
  • 11
    • 0034040746 scopus 로고    scopus 로고
    • Presence of bacterial DNA and bacterial peptidoglycans in joints of patients with rheumatoid arthritis and other arthritides
    • COI: 1:CAS:528:DC%2BD3cXitlGltrw%3D, PID: 10728753
    • van der Heijden IM, Wilbrink B, Tchetverikov I, Schrijver IA, Schouls LM, Hazenberg MP, Breedveld FC, Tak PP: Presence of bacterial DNA and bacterial peptidoglycans in joints of patients with rheumatoid arthritis and other arthritides. Arthritis Rheum. 2000, 43: 593-598. 10.1002/1529-0131(200003)43:3<593::AID-ANR16>3.0.CO;2-1. DOI: 10.1002/1529-0131(200003)43:3<593::AID-ANR16>3.0.CO;2-1
    • (2000) Arthritis Rheum , vol.43 , pp. 593-598
    • van der Heijden, I.M.1    Wilbrink, B.2    Tchetverikov, I.3    Schrijver, I.A.4    Schouls, L.M.5    Hazenberg, M.P.6    Breedveld, F.C.7    Tak, P.P.8
  • 13
    • 0029553672 scopus 로고
    • Collagen-induced arthritis in mice: synergistic effect of E. colilipopolysaccharide bypasses epitope specificity in the induction of arthritis with monoclonal antibodies to type II collagen
    • COI: 1:CAS:528:DyaK28XnsVOiu78%3D, PID: 8734568
    • Terato K, Harper DS, Griffiths MM, Hasty DL, Ye XJ, Cremer MA, Seyer JM: Collagen-induced arthritis in mice: synergistic effect of E. coli lipopolysaccharide bypasses epitope specificity in the induction of arthritis with monoclonal antibodies to type II collagen. Autoimmunity. 1995, 22: 137-147. DOI: 10.3109/08916939508995311
    • (1995) Autoimmunity , vol.22 , pp. 137-147
    • Terato, K.1    Harper, D.S.2    Griffiths, M.M.3    Hasty, D.L.4    Ye, X.J.5    Cremer, M.A.6    Seyer, J.M.7
  • 14
    • 0024362494 scopus 로고
    • Lyme Disease
    • COI: 1:STN:280:DyaL1MzksVWkuw%3D%3D, PID: 2668764
    • Steere AC: Lyme Disease. N Engl J Med. 1989, 321: 586-596. DOI: 10.1056/NEJM198908313210906
    • (1989) N Engl J Med , vol.321 , pp. 586-596
    • Steere, A.C.1
  • 15
    • 0025789064 scopus 로고
    • Borrelia burgdorferiactivates a T helper type 1-like T cell subset in Lyme arthritis
    • COI: 1:CAS:528:DyaK3MXltlert7c%3D, PID: 1831490
    • Yssel H, Shanafelt MC, Soderberg C, Schneider PV, Anzola J, Peltz G: Borrelia burgdorferi activates a T helper type 1-like T cell subset in Lyme arthritis. J Exp Med. 1991, 174: 593-601. 10.1084/jem.174.3.593. DOI: 10.1084/jem.174.3.593
    • (1991) J Exp Med , vol.174 , pp. 593-601
    • Yssel, H.1    Shanafelt, M.C.2    Soderberg, C.3    Schneider, P.V.4    Anzola, J.5    Peltz, G.6
  • 16
    • 0034153473 scopus 로고    scopus 로고
    • Isolation and characteristics of autoreactive T cells specific to aggrecan G1 domain from rheumatoid arthritis patients
    • COI: 1:STN:280:DC%2BD3c3islSnuw%3D%3D, PID: 10765982
    • Li NL, Zhang DQ, Zhou KY, Cartman A, Leroux JY, Poole AR, Zhang YP: Isolation and characteristics of autoreactive T cells specific to aggrecan G1 domain from rheumatoid arthritis patients. Cell Res. 2000, 10: 39-49. DOI: 10.1038/sj.cr.7290034
    • (2000) Cell Res , vol.10 , pp. 39-49
    • Li, N.L.1    Zhang, D.Q.2    Zhou, K.Y.3    Cartman, A.4    Leroux, J.Y.5    Poole, A.R.6    Zhang, Y.P.7
  • 18
    • 0035554950 scopus 로고    scopus 로고
    • Autoimmunity provoked by infection: how good is the case for T cell epitope mimicry?
    • COI: 1:CAS:528:DC%2BD3MXmsFehs7s%3D, PID: 11526389
    • Benoist C, Mathis D: Autoimmunity provoked by infection: how good is the case for T cell epitope mimicry?. Nat Immunol. 2001, 2: 797-801. 10.1038/ni0901-797. DOI: 10.1038/ni0901-797
    • (2001) Nat Immunol , vol.2 , pp. 797-801
    • Benoist, C.1    Mathis, D.2
  • 19
    • 0036484220 scopus 로고    scopus 로고
    • The B7-CD28 superfamily
    • COI: 1:CAS:528:DC%2BD38XitFSnu7s%3D, PID: 11910893
    • Sharpe AH, Freeman GJ: The B7-CD28 superfamily. Nat Rev Immunol. 2002, 2: 116-126. 10.1038/nri727. DOI: 10.1038/nri727
    • (2002) Nat Rev Immunol , vol.2 , pp. 116-126
    • Sharpe, A.H.1    Freeman, G.J.2
  • 20
    • 0024447275 scopus 로고
    • Activation of CD4 cells by fibronectin and anti-CD3 antibody. A synergistic effect mediated by the VLA-5 fibronectin receptor complex
    • COI: 1:CAS:528:DyaL1MXmtFehsr4%3D, PID: 2477485
    • Matsuyama T, Yamada A, Kay J, Yamada KM, Akiyama SK, Schlossman SF, Morimoto C: Activation of CD4 cells by fibronectin and anti-CD3 antibody. A synergistic effect mediated by the VLA-5 fibronectin receptor complex. J Exp Med. 1989, 170: 1133-1148. 10.1084/jem.170.4.1133. DOI: 10.1084/jem.170.4.1133
    • (1989) J Exp Med , vol.170 , pp. 1133-1148
    • Matsuyama, T.1    Yamada, A.2    Kay, J.3    Yamada, K.M.4    Akiyama, S.K.5    Schlossman, S.F.6    Morimoto, C.7
  • 21
    • 0025307161 scopus 로고
    • Costimulation of proliferative responses of resting CD4+ T cells by the interaction of VLA-4 and VLA-5 with fibronectin or VLA-6 with laminin
    • COI: 1:CAS:528:DyaK3cXlslShsbs%3D, PID: 1972721
    • Shimizu Y, van Seventer GA, Horgan KJ, Shaw S: Costimulation of proliferative responses of resting CD4+ T cells by the interaction of VLA-4 and VLA-5 with fibronectin or VLA-6 with laminin. J Immunol. 1990, 145: 59-67.
    • (1990) J Immunol , vol.145 , pp. 59-67
    • Shimizu, Y.1    van Seventer, G.A.2    Horgan, K.J.3    Shaw, S.4
  • 22
    • 0027255466 scopus 로고
    • The invasin protein of Yersiniaspp. provides co-stimulatory activity to human T cells through interaction with beta 1 integrins
    • COI: 1:CAS:528:DyaK3sXlslyrtb4%3D, PID: 8100774
    • Brett SJ, Mazurov AV, Charles IG, Tite JP: The invasin protein of Yersinia spp. provides co-stimulatory activity to human T cells through interaction with beta 1 integrins. Eur J Immunol. 1993, 23: 1608-1614. DOI: 10.1002/eji.1830230732
    • (1993) Eur J Immunol , vol.23 , pp. 1608-1614
    • Brett, S.J.1    Mazurov, A.V.2    Charles, I.G.3    Tite, J.P.4
  • 23
    • 0028953898 scopus 로고
    • The outer surface lipoprotein A of Borrelia burgdorferiprovides direct and indirect augmenting/co-stimulatory signals for the activation of CD4+ and CD8+ T cells
    • COI: 1:CAS:528:DyaK2MXkvFKjs78%3D, PID: 7622182
    • Simon MM, Nerz G, Kramer MD, Hurtenbach U, Schaible UE, Wallich R: The outer surface lipoprotein A of Borrelia burgdorferi provides direct and indirect augmenting/co-stimulatory signals for the activation of CD4+ and CD8+ T cells. Immunol Lett. 1995, 45: 137-142. 10.1016/0165-2478(94)00243-K. DOI: 10.1016/0165-2478(94)00243-K
    • (1995) Immunol Lett , vol.45 , pp. 137-142
    • Simon, M.M.1    Nerz, G.2    Kramer, M.D.3    Hurtenbach, U.4    Schaible, U.E.5    Wallich, R.6
  • 24
    • 0029797164 scopus 로고    scopus 로고
    • The outer surface lipoprotein OspA of Borrelia burgdorferiprovides co- stimulatory signals to normal human peripheral CD4+ and CD8+ T lymphocytes
    • COI: 1:CAS:528:DyaK28XmsV2gu7c%3D, PID: 8898937
    • Knigge H, Simon MM, Meuer SC, Kramer MD, Wallich R: The outer surface lipoprotein OspA of Borrelia burgdorferi provides co- stimulatory signals to normal human peripheral CD4+ and CD8+ T lymphocytes. Eur J Immunol. 1996, 26: 2299-2303. DOI: 10.1002/eji.1830261005
    • (1996) Eur J Immunol , vol.26 , pp. 2299-2303
    • Knigge, H.1    Simon, M.M.2    Meuer, S.C.3    Kramer, M.D.4    Wallich, R.5
  • 25
    • 0022568935 scopus 로고
    • B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells
    • COI: 1:CAS:528:DyaL28XksVSrur0%3D, PID: 3486902
    • Coffman RL, Ohara J, Bond MW, Carty J, Zlotnik A, Paul WE: B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells. J Immunol. 1986, 136: 4538-4541.
    • (1986) J Immunol , vol.136 , pp. 4538-4541
    • Coffman, R.L.1    Ohara, J.2    Bond, M.W.3    Carty, J.4    Zlotnik, A.5    Paul, W.E.6
  • 26
    • 0033830592 scopus 로고    scopus 로고
    • The road to the production of IgE is long and winding
    • COI: 1:STN:280:DC%2BD3M%2FgvValsg%3D%3D, PID: 10988155
    • Karnowski A, Yu P, Achatz G, Lamers MC: The road to the production of IgE is long and winding. Am J Respir Crit Care Med. 2000, 162: S71-S75. DOI: 10.1164/ajrccm.162.supplement_2.ras-3
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. S71-S75
    • Karnowski, A.1    Yu, P.2    Achatz, G.3    Lamers, M.C.4
  • 27
    • 0032509295 scopus 로고    scopus 로고
    • Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene
    • COI: 1:CAS:528:DyaK1cXotVyjsbk%3D, PID: 9851930
    • Poltorak A, He X, Smirnova I, Liu MY, Van Huffel C, Du X, Birdwell D, Alejos E, Silva M, Galanos C, et al: Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science. 1998, 282: 2085-2088. 10.1126/science.282.5396.2085. DOI: 10.1126/science.282.5396.2085
    • (1998) Science , vol.282 , pp. 2085-2088
    • Poltorak, A.1    He, X.2    Smirnova, I.3    Liu, M.Y.4    Van Huffel, C.5    Du, X.6    Birdwell, D.7    Alejos, E.8    Silva, M.9    Galanos, C.10
  • 28
    • 0031774181 scopus 로고    scopus 로고
    • Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide
    • COI: 1:CAS:528:DyaK1cXnvFOhu7o%3D, PID: 9841923
    • Kirschning CJ, Wesche H, Merrill Ayres T, Rothe M: Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide. J Exp Med. 1998, 188: 2091-2097. 10.1084/jem.188.11.2091. DOI: 10.1084/jem.188.11.2091
    • (1998) J Exp Med , vol.188 , pp. 2091-2097
    • Kirschning, C.J.1    Wesche, H.2    Merrill Ayres, T.3    Rothe, M.4
  • 30
    • 0035881244 scopus 로고    scopus 로고
    • A point mutation in the IL-12R beta 2 gene underlies the IL-12 unresponsiveness of Lps-defective C57BL/10ScCr mice
    • COI: 1:CAS:528:DC%2BD3MXlvFequrg%3D, PID: 11489994
    • Poltorak A, Merlin T, Nielsen PJ, Sandra O, Smirnova I, Schupp I, Boehm T, Galanos C, Freudenberg MA: A point mutation in the IL-12R beta 2 gene underlies the IL-12 unresponsiveness of Lps-defective C57BL/10ScCr mice. J Immunol. 2001, 167: 2106-2111. DOI: 10.4049/jimmunol.167.4.2106
    • (2001) J Immunol , vol.167 , pp. 2106-2111
    • Poltorak, A.1    Merlin, T.2    Nielsen, P.J.3    Sandra, O.4    Smirnova, I.5    Schupp, I.6    Boehm, T.7    Galanos, C.8    Freudenberg, M.A.9
  • 31
    • 0025333897 scopus 로고
    • Monoclonal antibodies specific for the outer surface protein A (OspA) of Borrelia burgdorferiprevent Lyme borreliosis in severe combined immunodeficiency (scid) mice
    • COI: 1:CAS:528:DyaK3cXkslKjtrk%3D, PID: 2339119
    • Schaible UE, Kramer MD, Eichmann K, Modolell M, Museteanu C, Simon MM: Monoclonal antibodies specific for the outer surface protein A (OspA) of Borrelia burgdorferi prevent Lyme borreliosis in severe combined immunodeficiency (scid) mice. Proc Natl Acad Sci USA. 1990, 87: 3768-3772. DOI: 10.1073/pnas.87.10.3768
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 3768-3772
    • Schaible, U.E.1    Kramer, M.D.2    Eichmann, K.3    Modolell, M.4    Museteanu, C.5    Simon, M.M.6
  • 32
    • 0030723209 scopus 로고    scopus 로고
    • In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A × B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells
    • COI: 1:CAS:528:DyaK2sXnsVeit7w%3D, PID: 9362539
    • Simon MM, Hausmann M, Tran T, Ebnet K, Tschopp J, Tha Hla R, Mullbacher A: In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A × B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells. J Exp Med. 1997, 186: 1781-1786. 10.1084/jem.186.10.1781. DOI: 10.1084/jem.186.10.1781
    • (1997) J Exp Med , vol.186 , pp. 1781-1786
    • Simon, M.M.1    Hausmann, M.2    Tran, T.3    Ebnet, K.4    Tschopp, J.5    Tha Hla, R.6    Mullbacher, A.7
  • 33
    • 85047690873 scopus 로고    scopus 로고
    • Antagonistic antibody prevents toll-like receptor 2-driven lethal shock-like syndromes
    • COI: 1:CAS:528:DC%2BD2cXktlClt78%3D, PID: 15146245
    • Meng G, Rutz M, Schiemann M, Metzger J, Grabiec A, Schwandner R, Luppa PB, Ebel F, Busch DH, Bauer S, et al: Antagonistic antibody prevents toll-like receptor 2-driven lethal shock-like syndromes. J Clin Invest. 2004, 113: 1473-1481. 10.1172/JCI200420762. DOI: 10.1172/JCI20762
    • (2004) J Clin Invest , vol.113 , pp. 1473-1481
    • Meng, G.1    Rutz, M.2    Schiemann, M.3    Metzger, J.4    Grabiec, A.5    Schwandner, R.6    Luppa, P.B.7    Ebel, F.8    Busch, D.H.9    Bauer, S.10
  • 34
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • COI: 1:CAS:528:DyaL2sXitFSns7Y%3D, PID: 2440339
    • Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 1987, 162: 156-159. 10.1006/abio.1987.9999. DOI: 10.1016/0003-2697(87)90021-2
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 36
    • 0036344106 scopus 로고    scopus 로고
    • Hyporesponsiveness to vaccination with Borrelia burgdorferiOspA in humans and in TLR1- and TLR2-deficient mice
    • COI: 1:CAS:528:DC%2BD38Xls12msLg%3D, PID: 12091878
    • Alexopoulou L, Thomas V, Schnare M, Lobet Y, Anguita J, Schoen RT, Medzhitov R, Fikrig E, Flavell RA: Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice. Nat Med. 2002, 8: 878-884.
    • (2002) Nat Med , vol.8 , pp. 878-884
    • Alexopoulou, L.1    Thomas, V.2    Schnare, M.3    Lobet, Y.4    Anguita, J.5    Schoen, R.T.6    Medzhitov, R.7    Fikrig, E.8    Flavell, R.A.9
  • 37
    • 0036644042 scopus 로고    scopus 로고
    • Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins
    • COI: 1:CAS:528:DC%2BD38XltVKjtbs%3D, PID: 12077222
    • Takeuchi O, Sato S, Horiuchi T, Hoshino K, Takeda K, Dong Z, Modlin RL, Akira S: Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. J Immunol. 2002, 169: 10-14. DOI: 10.4049/jimmunol.169.1.10
    • (2002) J Immunol , vol.169 , pp. 10-14
    • Takeuchi, O.1    Sato, S.2    Horiuchi, T.3    Hoshino, K.4    Takeda, K.5    Dong, Z.6    Modlin, R.L.7    Akira, S.8
  • 38
    • 0037290876 scopus 로고    scopus 로고
    • Mammalian Toll-like receptors
    • COI: 1:CAS:528:DC%2BD38XpsFegsLw%3D, PID: 12495726
    • Akira S: Mammalian Toll-like receptors. Curr Opin Immunol. 2003, 15: 5-11. 10.1016/S0952-7915(02)00013-4. DOI: 10.1016/S0952-7915(02)00013-4
    • (2003) Curr Opin Immunol , vol.15 , pp. 5-11
    • Akira, S.1
  • 39
    • 0034610291 scopus 로고    scopus 로고
    • The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
    • COI: 1:CAS:528:DC%2BD3cXoslyns7w%3D, PID: 11095740
    • Ozinsky A, Underhill DM, Fontenot JD, Hajjar AM, Smith KD, Wilson CB, Schroeder L, Aderem A: The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc Natl Acad Sci USA. 2000, 97: 13766-13771. 10.1073/pnas.250476497. DOI: 10.1073/pnas.250476497
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13766-13771
    • Ozinsky, A.1    Underhill, D.M.2    Fontenot, J.D.3    Hajjar, A.M.4    Smith, K.D.5    Wilson, C.B.6    Schroeder, L.7    Aderem, A.8
  • 40
    • 0035879283 scopus 로고    scopus 로고
    • Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferiouter surface protein A lipoprotein: role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling
    • COI: 1:CAS:528:DC%2BD3MXotFWktLs%3D, PID: 11441107
    • Bulut Y, Faure E, Thomas L, Equils O, Arditi M: Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling. J Immunol. 2001, 167: 987-994. DOI: 10.4049/jimmunol.167.2.987
    • (2001) J Immunol , vol.167 , pp. 987-994
    • Bulut, Y.1    Faure, E.2    Thomas, L.3    Equils, O.4    Arditi, M.5
  • 41
    • 0036918723 scopus 로고    scopus 로고
    • Differential recognition of structural details of bacterial lipopeptides by toll-like receptors
    • COI: 1:CAS:528:DC%2BD3sXjt1Gk, PID: 12432564
    • Morr M, Takeuchi O, Akira S, Simon MM, Muhlradt PF: Differential recognition of structural details of bacterial lipopeptides by toll-like receptors. Eur J Immunol. 2002, 32: 3337-3347. 10.1002/1521-4141(2002012)32:12<3337::AID-IMMU3337>3.0.CO;2-I. DOI: 10.1002/1521-4141(2002012)32:12<3337::AID-IMMU3337>3.0.CO;2-I
    • (2002) Eur J Immunol , vol.32 , pp. 3337-3347
    • Morr, M.1    Takeuchi, O.2    Akira, S.3    Simon, M.M.4    Muhlradt, P.F.5
  • 42
    • 0034680145 scopus 로고    scopus 로고
    • Toll-like receptors in the induction of the innate immune response
    • COI: 1:STN:280:DC%2BD3cvjtVOhuw%3D%3D, PID: 10963608
    • Aderem A, Ulevitch RJ: Toll-like receptors in the induction of the innate immune response. Nature. 2000, 406: 782-787. 10.1038/35021228. DOI: 10.1038/35021228
    • (2000) Nature , vol.406 , pp. 782-787
    • Aderem, A.1    Ulevitch, R.J.2
  • 43
    • 0034775153 scopus 로고    scopus 로고
    • Toll-like receptors control activation of adaptive immune responses
    • COI: 1:CAS:528:DC%2BD3MXnsVCis74%3D, PID: 11547333
    • Schnare M, Barton GM, Holt AC, Takeda K, Akira S, Medzhitov R: Toll-like receptors control activation of adaptive immune responses. Nat Immunol. 2001, 2: 947-950. 10.1038/ni712. DOI: 10.1038/ni712
    • (2001) Nat Immunol , vol.2 , pp. 947-950
    • Schnare, M.1    Barton, G.M.2    Holt, A.C.3    Takeda, K.4    Akira, S.5    Medzhitov, R.6
  • 44
    • 0036735155 scopus 로고    scopus 로고
    • Variable expression of Toll-like receptor in murine innate and adaptive immune cell lines
    • COI: 1:CAS:528:DC%2BD38Xms1GmsrY%3D, PID: 12202403
    • Applequist SE, Wallin RP, Ljunggren HG: Variable expression of Toll-like receptor in murine innate and adaptive immune cell lines. Int Immunol. 2002, 14: 1065-1074. 10.1093/intimm/dxf069. DOI: 10.1093/intimm/dxf069
    • (2002) Int Immunol , vol.14 , pp. 1065-1074
    • Applequist, S.E.1    Wallin, R.P.2    Ljunggren, H.G.3
  • 45
    • 0035164253 scopus 로고    scopus 로고
    • Regulation of Toll-like receptors in human monocytes and dendritic cells
    • COI: 1:CAS:528:DC%2BD3MXis1aqtg%3D%3D, PID: 11123299
    • Visintin A, Mazzoni A, Spitzer JH, Wyllie DH, Dower SK, Segal DM: Regulation of Toll-like receptors in human monocytes and dendritic cells. J Immunol. 2001, 166: 249-255. DOI: 10.4049/jimmunol.166.1.249
    • (2001) J Immunol , vol.166 , pp. 249-255
    • Visintin, A.1    Mazzoni, A.2    Spitzer, J.H.3    Wyllie, D.H.4    Dower, S.K.5    Segal, D.M.6
  • 46
    • 0037450804 scopus 로고    scopus 로고
    • Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide
    • COI: 1:CAS:528:DC%2BD3sXhtlOls7s%3D, PID: 12591899
    • Caramalho I, Lopes-Carvalho T, Ostler D, Zelenay S, Haury M, Demengeot J: Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide. J Exp Med. 2003, 197: 403-411. 10.1084/jem.20021633. DOI: 10.1084/jem.20021633
    • (2003) J Exp Med , vol.197 , pp. 403-411
    • Caramalho, I.1    Lopes-Carvalho, T.2    Ostler, D.3    Zelenay, S.4    Haury, M.5    Demengeot, J.6
  • 48
    • 0028965644 scopus 로고
    • Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin
    • COI: 1:CAS:528:DyaK2MXltFamur0%3D, PID: 7542010
    • Ulevitch RJ, Tobias PS: Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu Rev Immunol. 1995, 13: 437-457. 10.1146/annurev.iy.13.040195.002253. DOI: 10.1146/annurev.iy.13.040195.002253
    • (1995) Annu Rev Immunol , vol.13 , pp. 437-457
    • Ulevitch, R.J.1    Tobias, P.S.2
  • 49
    • 0037322295 scopus 로고    scopus 로고
    • Toll signaling: the TIReless quest for specificity
    • COI: 1:CAS:528:DC%2BD3sXmslGqtw%3D%3D, PID: 12555093
    • Imler JL, Hoffmann JA: Toll signaling: the TIReless quest for specificity. Nat Immunol. 2003, 4: 105-106. 10.1038/ni0203-105. DOI: 10.1038/ni0203-105
    • (2003) Nat Immunol , vol.4 , pp. 105-106
    • Imler, J.L.1    Hoffmann, J.A.2
  • 50
    • 0036864723 scopus 로고    scopus 로고
    • Wanted: a molecular basis for specificity in toll-like receptor signal transduction
    • PID: 12453406
    • O'Neill LA: Wanted: a molecular basis for specificity in toll-like receptor signal transduction. Mol Cell. 2002, 10: 969-971. 10.1016/S1097-2765(02)00754-2. DOI: 10.1016/S1097-2765(02)00754-2
    • (2002) Mol Cell , vol.10 , pp. 969-971
    • O'Neill, L.A.1
  • 51
    • 0038242875 scopus 로고    scopus 로고
    • Toll-like receptor signaling pathways
    • COI: 1:CAS:528:DC%2BD3sXktlKru7w%3D, PID: 12791976
    • Barton GM, Medzhitov R: Toll-like receptor signaling pathways. Science. 2003, 300: 1524-1525. 10.1126/science.1085536. DOI: 10.1126/science.1085536
    • (2003) Science , vol.300 , pp. 1524-1525
    • Barton, G.M.1    Medzhitov, R.2
  • 52
    • 0036679733 scopus 로고    scopus 로고
    • It's all Rel-ative: NF-κB and CD28 costimulation of T-cell activation
    • COI: 1:CAS:528:DC%2BD38XlsVGqurY%3D, PID: 12133805
    • Kane LP, Lin J, Weiss A: It's all Rel-ative: NF-κB and CD28 costimulation of T-cell activation. Trends Immunol. 2002, 23: 413-420. 10.1016/S1471-4906(02)02264-0. DOI: 10.1016/S1471-4906(02)02264-0
    • (2002) Trends Immunol , vol.23 , pp. 413-420
    • Kane, L.P.1    Lin, J.2    Weiss, A.3
  • 53
    • 0033618630 scopus 로고    scopus 로고
    • Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2
    • COI: 1:CAS:528:DyaK1MXltVehsLg%3D, PID: 10426996
    • Aliprantis AO, Yang RB, Mark MR, Suggett S, Devaux B, Radolf JD, Klimpel GR, Godowski P, Zychlinsky A: Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. Science. 1999, 285: 736-739. 10.1126/science.285.5428.736. DOI: 10.1126/science.285.5428.736
    • (1999) Science , vol.285 , pp. 736-739
    • Aliprantis, A.O.1    Yang, R.B.2    Mark, M.R.3    Suggett, S.4    Devaux, B.5    Radolf, J.D.6    Klimpel, G.R.7    Godowski, P.8    Zychlinsky, A.9
  • 55
    • 0031977605 scopus 로고    scopus 로고
    • The role of CD40/CD154 interactions in the priming, differentiation, and effector function of helper and cytotoxic T cells
    • COI: 1:CAS:528:DyaK1cXisVSns70%3D, PID: 9544571
    • Mackey MF, Barth RJ, Noelle RJ: The role of CD40/CD154 interactions in the priming, differentiation, and effector function of helper and cytotoxic T cells. J Leukoc Biol. 1998, 63: 418-428.
    • (1998) J Leukoc Biol , vol.63 , pp. 418-428
    • Mackey, M.F.1    Barth, R.J.2    Noelle, R.J.3
  • 56
    • 0030846262 scopus 로고    scopus 로고
    • Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells
    • COI: 1:CAS:528:DyaK2sXlvVeitL0%3D, PID: 9271591
    • Itoh Y, Germain RN: Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells. J Exp Med. 1997, 186: 757-766. 10.1084/jem.186.5.757. DOI: 10.1084/jem.186.5.757
    • (1997) J Exp Med , vol.186 , pp. 757-766
    • Itoh, Y.1    Germain, R.N.2
  • 57
    • 0031739790 scopus 로고    scopus 로고
    • Partial agonism and independent modulation of T cell receptor and CD8 in hapten-specific cytotoxic T cells
    • COI: 1:CAS:528:DyaK1cXnsFKjs78%3D, PID: 9842913
    • Preckel T, Breloer M, Kohler H, von Bonin A, Weltzien HU: Partial agonism and independent modulation of T cell receptor and CD8 in hapten-specific cytotoxic T cells. Eur J Immunol. 1998, 28: 3706-3718. 10.1002/(SICI)1521-4141(199811)28:11<3706::AID-IMMU3706>3.0.CO;2-7. DOI: 10.1002/(SICI)1521-4141(199811)28:11<3706::AID-IMMU3706>3.0.CO;2-7
    • (1998) Eur J Immunol , vol.28 , pp. 3706-3718
    • Preckel, T.1    Breloer, M.2    Kohler, H.3    von Bonin, A.4    Weltzien, H.U.5
  • 58
    • 0025130575 scopus 로고
    • Retroviruses and autoimmunity
    • COI: 1:STN:280:DyaK3c3ltlGgsA%3D%3D, PID: 2160242
    • Krieg AM, Steinberg AD: Retroviruses and autoimmunity. J Autoimmun. 1990, 3: 137-166. 10.1016/0896-8411(90)90137-H. DOI: 10.1016/0896-8411(90)90137-H
    • (1990) J Autoimmun , vol.3 , pp. 137-166
    • Krieg, A.M.1    Steinberg, A.D.2
  • 59
    • 0026558120 scopus 로고
    • Slow bacterial infections or autoimmunity?
    • COI: 1:CAS:528:DyaK38XltV2msr4%3D, PID: 1642753
    • Rook GA, Stanford JL: Slow bacterial infections or autoimmunity?. Immunol Today. 1992, 13: 160-164. 10.1016/0167-5699(92)90119-R. DOI: 10.1016/0167-5699(92)90119-R
    • (1992) Immunol Today , vol.13 , pp. 160-164
    • Rook, G.A.1    Stanford, J.L.2
  • 60
    • 0034601022 scopus 로고    scopus 로고
    • The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells
    • COI: 1:CAS:528:DC%2BD3cXkslaitLo%3D, PID: 10880523
    • Ogata H, Su I, Miyake K, Nagai Y, Akashi S, Mecklenbrauker I, Rajewsky K, Kimoto M, Tarakhovsky A: The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells. J Exp Med. 2000, 192: 23-29. 10.1084/jem.192.1.23. DOI: 10.1084/jem.192.1.23
    • (2000) J Exp Med , vol.192 , pp. 23-29
    • Ogata, H.1    Su, I.2    Miyake, K.3    Nagai, Y.4    Akashi, S.5    Mecklenbrauker, I.6    Rajewsky, K.7    Kimoto, M.8    Tarakhovsky, A.9
  • 61
    • 0033822039 scopus 로고    scopus 로고
    • B-cell activation by T-cell-independent type 2 antigens as an integral part of the humoral immune response to pathogenic microorganisms
    • COI: 1:CAS:528:DC%2BD3cXntFOgtLo%3D, PID: 11043775
    • Vos Q, Lees A, Wu ZQ, Snapper CM, Mond JJ: B-cell activation by T-cell-independent type 2 antigens as an integral part of the humoral immune response to pathogenic microorganisms. Immunol Rev. 2000, 176: 154-170. 10.1034/j.1600-065X.2000.00607.x. DOI: 10.1034/j.1600-065X.2000.00607.x
    • (2000) Immunol Rev , vol.176 , pp. 154-170
    • Vos, Q.1    Lees, A.2    Wu, Z.Q.3    Snapper, C.M.4    Mond, J.J.5
  • 62
    • 0043205830 scopus 로고    scopus 로고
    • T cells respond to heat shock protein 60 via TLR2: activation of adhesion and inhibition of chemokine receptors
    • COI: 1:CAS:528:DC%2BD3sXmtVKnsbw%3D, PID: 12824285
    • Zanin-Zhorov A, Nussbaum G, Franitza S, Cohen IR, Lider O: T cells respond to heat shock protein 60 via TLR2: activation of adhesion and inhibition of chemokine receptors. FASEB J. 2003, 17: 1567-1569.
    • (2003) FASEB J , vol.17 , pp. 1567-1569
    • Zanin-Zhorov, A.1    Nussbaum, G.2    Franitza, S.3    Cohen, I.R.4    Lider, O.5
  • 63
    • 0018775078 scopus 로고
    • Immune interferon in the circulation of patients with autoimmune disease
    • COI: 1:STN:280:DyaE1M7pvFCgsA%3D%3D, PID: 449915
    • Hooks JJ, Moutsopoulos HM, Geis SA, Stahl NI, Decker JL, Notkins AL: Immune interferon in the circulation of patients with autoimmune disease. N Engl J Med. 1979, 301: 5-8. DOI: 10.1056/NEJM197907053010102
    • (1979) N Engl J Med , vol.301 , pp. 5-8
    • Hooks, J.J.1    Moutsopoulos, H.M.2    Geis, S.A.3    Stahl, N.I.4    Decker, J.L.5    Notkins, A.L.6
  • 64
    • 0036153879 scopus 로고    scopus 로고
    • Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis
    • COI: 1:CAS:528:DC%2BD38XhsFaksw%3D%3D, PID: 11879537
    • Kaplan C, Valdez JC, Chandrasekaran R, Eibel H, Mikecz K, Glant TT, Finnegan A: Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis. Arthritis Res. 2002, 4: 54-58. 10.1186/ar383. DOI: 10.1186/ar383
    • (2002) Arthritis Res , vol.4 , pp. 54-58
    • Kaplan, C.1    Valdez, J.C.2    Chandrasekaran, R.3    Eibel, H.4    Mikecz, K.5    Glant, T.T.6    Finnegan, A.7
  • 65
    • 0035053491 scopus 로고    scopus 로고
    • The role of IFN-gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity
    • COI: 1:CAS:528:DC%2BD3MXjsFOmsL0%3D, PID: 11299053
    • Theofilopoulos AN, Koundouris S, Kono DH, Lawson BR: The role of IFN-gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity. Arthritis Res. 2001, 3: 136-141. 10.1186/ar290. DOI: 10.1186/ar290
    • (2001) Arthritis Res , vol.3 , pp. 136-141
    • Theofilopoulos, A.N.1    Koundouris, S.2    Kono, D.H.3    Lawson, B.R.4
  • 66
    • 0032750902 scopus 로고    scopus 로고
    • The elevated ratio of interferon gamma-/interleukin-4-positive T cells found in synovial fluid and synovial membrane of rheumatoid arthritis patients can be changed by interleukin-4 but not by interleukin-10 or transforming growth factor beta
    • COI: 1:CAS:528:DyaK1MXotV2jsbo%3D
    • Yin Z, Siegert S, Neure L, Grolms M, Liu L, Eggens U, Radbruch A, Braun J, Sieper J: The elevated ratio of interferon gamma-/interleukin-4-positive T cells found in synovial fluid and synovial membrane of rheumatoid arthritis patients can be changed by interleukin-4 but not by interleukin-10 or transforming growth factor beta. Rheumatology (Oxford). 1999, 38: 1058-1067. 10.1093/rheumatology/38.11.1058. DOI: 10.1093/rheumatology/38.11.1058
    • (1999) Rheumatology (Oxford) , vol.38 , pp. 1058-1067
    • Yin, Z.1    Siegert, S.2    Neure, L.3    Grolms, M.4    Liu, L.5    Eggens, U.6    Radbruch, A.7    Braun, J.8    Sieper, J.9
  • 68
    • 0025027636 scopus 로고
    • Lyme borreliosis in the severe combined immunodeficiency (scid) mouse manifests predominantly in the joints, heart, and liver
    • COI: 1:STN:280:DyaK3M%2Fit12kug%3D%3D, PID: 2221014
    • Schaible UE, Gay S, Museteanu C, Kramer MD, Zimmer G, Eichmann K, Museteanu U, Simon MM: Lyme borreliosis in the severe combined immunodeficiency (scid) mouse manifests predominantly in the joints, heart, and liver. Am J Pathol. 1990, 137: 811-820.
    • (1990) Am J Pathol , vol.137 , pp. 811-820
    • Schaible, U.E.1    Gay, S.2    Museteanu, C.3    Kramer, M.D.4    Zimmer, G.5    Eichmann, K.6    Museteanu, U.7    Simon, M.M.8
  • 69
    • 0025938412 scopus 로고
    • Experimental Borrelia burgdorferiinfection in inbred mouse strains: antibody response and association of H-2 genes with resistance and susceptibility to development of arthritis
    • COI: 1:CAS:528:DyaK38XhvFGntA%3D%3D, PID: 1915553
    • Schaible UE, Kramer MD, Wallich R, Tran T, Simon MM: Experimental Borrelia burgdorferi infection in inbred mouse strains: antibody response and association of H-2 genes with resistance and susceptibility to development of arthritis. Eur J Immunol. 1991, 21: 2397-2405. DOI: 10.1002/eji.1830211016
    • (1991) Eur J Immunol , vol.21 , pp. 2397-2405
    • Schaible, U.E.1    Kramer, M.D.2    Wallich, R.3    Tran, T.4    Simon, M.M.5
  • 71
    • 0027513975 scopus 로고
    • Specific and nonspecific responses of murine B cells to membrane blebs of Borrelia burgdorferi
    • COI: 1:CAS:528:DyaK3sXitlaisbY%3D, PID: 8454350
    • Whitmire WM, Garon CF: Specific and nonspecific responses of murine B cells to membrane blebs of Borrelia burgdorferi. Infect Immun. 1993, 61: 1460-1467.
    • (1993) Infect Immun , vol.61 , pp. 1460-1467
    • Whitmire, W.M.1    Garon, C.F.2
  • 72
    • 0025290553 scopus 로고
    • Association of chronic Lyme arthritis with HLA-DR4 and HLA-DR2 alleles
    • COI: 1:STN:280:DyaK3czgvF2juw%3D%3D, PID: 2078208
    • Steere AC, Dwyer E, Winchester R: Association of chronic Lyme arthritis with HLA-DR4 and HLA-DR2 alleles. N Engl J Med. 1990, 323: 219-223. DOI: 10.1056/NEJM199007263230402
    • (1990) N Engl J Med , vol.323 , pp. 219-223
    • Steere, A.C.1    Dwyer, E.2    Winchester, R.3
  • 73
    • 0025861754 scopus 로고
    • Clinical definitions and differential diagnosis of Lyme arthritis
    • COI: 1:STN:280:DyaK38%2FlsVaktw%3D%3D, PID: 1947812
    • Steere AC: Clinical definitions and differential diagnosis of Lyme arthritis. Scand J Infect Dis Suppl. 1991, 77: 51-54.
    • (1991) Scand J Infect Dis Suppl , vol.77 , pp. 51-54
    • Steere, A.C.1
  • 74
    • 0025292436 scopus 로고
    • Lyme borreliosis in selected strains and ages of laboratory mice
    • COI: 1:STN:280:DyaK3c3osFGjtg%3D%3D, PID: 2141344
    • Barthold SW, Beck DS, Hansen GM, Terwilliger GA, Moody KD: Lyme borreliosis in selected strains and ages of laboratory mice. J Infect Dis. 1990, 162: 133-138. DOI: 10.1093/infdis/162.1.133
    • (1990) J Infect Dis , vol.162 , pp. 133-138
    • Barthold, S.W.1    Beck, D.S.2    Hansen, G.M.3    Terwilliger, G.A.4    Moody, K.D.5
  • 75
    • 0032584605 scopus 로고    scopus 로고
    • Identification of LFA-1 as a candidate autoantigen in treatment-resistant Lyme arthritis
    • COI: 1:CAS:528:DyaK1cXltFelt70%3D, PID: 9685265
    • Gross DM, Forsthuber T, Tary-Lehmann M, Etling C, Ito K, Nagy ZA, Field JA, Steere AC, Huber BT: Identification of LFA-1 as a candidate autoantigen in treatment-resistant Lyme arthritis. Science. 1998, 281: 703-706. 10.1126/science.281.5377.703. DOI: 10.1126/science.281.5377.703
    • (1998) Science , vol.281 , pp. 703-706
    • Gross, D.M.1    Forsthuber, T.2    Tary-Lehmann, M.3    Etling, C.4    Ito, K.5    Nagy, Z.A.6    Field, J.A.7    Steere, A.C.8    Huber, B.T.9
  • 76
    • 0035871803 scopus 로고    scopus 로고
    • Molecular mimicry in Lyme arthritis demonstrated at the single cell level: LFA-1 alpha L is a partial agonist for outer surface protein A-reactive T cells
    • COI: 1:CAS:528:DC%2BD3MXivVKmtrw%3D, PID: 11290815
    • Trollmo C, Meyer AL, Steere AC, Hafler DA, Huber BT: Molecular mimicry in Lyme arthritis demonstrated at the single cell level: LFA-1 alpha L is a partial agonist for outer surface protein A-reactive T cells. J Immunol. 2001, 166: 5286-5291. DOI: 10.4049/jimmunol.166.8.5286
    • (2001) J Immunol , vol.166 , pp. 5286-5291
    • Trollmo, C.1    Meyer, A.L.2    Steere, A.C.3    Hafler, D.A.4    Huber, B.T.5
  • 77
    • 0037331560 scopus 로고    scopus 로고
    • Binding of outer surface protein A and human lymphocyte function-associated antigen 1 peptides to HLA-DR molecules associated with antibiotic treatment-resistant Lyme arthritis
    • COI: 1:CAS:528:DC%2BD3sXhslKktb0%3D, PID: 12571864
    • Steere AC, Falk B, Drouin EE, Baxter-Lowe LA, Hammer J, Nepom GT: Binding of outer surface protein A and human lymphocyte function-associated antigen 1 peptides to HLA-DR molecules associated with antibiotic treatment-resistant Lyme arthritis. Arthritis Rheum. 2003, 48: 534-540. 10.1002/art.10772. DOI: 10.1002/art.10772
    • (2003) Arthritis Rheum , vol.48 , pp. 534-540
    • Steere, A.C.1    Falk, B.2    Drouin, E.E.3    Baxter-Lowe, L.A.4    Hammer, J.5    Nepom, G.T.6
  • 78
    • 1142310887 scopus 로고    scopus 로고
    • Elucidation of Lyme arthritis
    • COI: 1:CAS:528:DC%2BD2cXhsVKqtb8%3D, PID: 15040587
    • Steere AC, Glickstein L: Elucidation of Lyme arthritis. Nat Rev Immunol. 2004, 4: 143-152. 10.1038/nri1267. DOI: 10.1038/nri1267
    • (2004) Nat Rev Immunol , vol.4 , pp. 143-152
    • Steere, A.C.1    Glickstein, L.2
  • 79
    • 0037217711 scopus 로고    scopus 로고
    • Human T lymphocyte response to Borrelia burgdorferiinfection: no correlation between human leukocyte function antigen type 1 peptide response and clinical status
    • COI: 1:CAS:528:DC%2BD3sXotFGntQ%3D%3D, PID: 12508152
    • Kalish RS, Wood JA, Golde W, Bernard R, Davis LE, Grimson RC, Coyle PK, Luft BJ: Human T lymphocyte response to Borrelia burgdorferi infection: no correlation between human leukocyte function antigen type 1 peptide response and clinical status. J Infect Dis. 2003, 187: 102-108. 10.1086/346059. DOI: 10.1086/346059
    • (2003) J Infect Dis , vol.187 , pp. 102-108
    • Kalish, R.S.1    Wood, J.A.2    Golde, W.3    Bernard, R.4    Davis, L.E.5    Grimson, R.C.6    Coyle, P.K.7    Luft, B.J.8
  • 80
    • 0026743048 scopus 로고
    • Altered patterns of T cell migration through lymph nodes and skin following antigen challenge
    • COI: 1:CAS:528:DyaK3sXlslKnsw%3D%3D, PID: 1381308
    • Mackay CR, Marston W, Dudler L: Altered patterns of T cell migration through lymph nodes and skin following antigen challenge. Eur J Immunol. 1992, 22: 2205-2210. DOI: 10.1002/eji.1830220904
    • (1992) Eur J Immunol , vol.22 , pp. 2205-2210
    • Mackay, C.R.1    Marston, W.2    Dudler, L.3
  • 81
    • 0026815051 scopus 로고
    • Migration pathways and immunologic memory among T lymphocytes
    • COI: 1:CAS:528:DyaK2cXmtVamu7Y%3D, PID: 1534264
    • Mackay CR: Migration pathways and immunologic memory among T lymphocytes. Semin Immunol. 1992, 4: 51-58.
    • (1992) Semin Immunol , vol.4 , pp. 51-58
    • Mackay, C.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.