Human cartilage glycoprotein-39 as a candidate autoantigen in rheumatoid arthritis

Arthritis and Rheumatism

Volumn 40, Issue 6, 1997, Pages 1115-1125

  Verheijden, Gijs F M ^a   Rijnders, Antonius W M ^a   Bos, Ebo ^a   Coenen De Roo, Christina J J ^a   Van Staveren, Catherina J ^a   Miltenburg, André M M ^a   Meijerink, Jan H ^a   Elewaut, Dirk ^b   De Keyser, Filip ^b   Veys, Eric ^b   Boots, Annemieke M H ^a,c  

^a NV ORGANON   (Netherlands)

^b GHENT UNIVERSITY HOSPITAL   (Belgium)

^c NV Organon ^*  (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; GLYCOPROTEIN GP 39;

ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE MATRIX; DNA SEQUENCE; GENETIC SUSCEPTIBILITY; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; MAJOR HISTOCOMPATIBILITY COMPLEX; MONONUCLEAR CELL; OPEN READING FRAME; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; AUTOANTIGENS; CARTILAGE; CLONE CELLS; EPITOPES; FEMALE; GLYCOPROTEINS; HUMANS; IMMUNE TOLERANCE; MALE; MICE; MICE, INBRED BALB C; MIDDLE AGED; PEPTIDES; T-LYMPHOCYTES;

EID: 0030904638     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.1780400616     Document Type: Article

References (36)

1. Harris ED: Rheumatoid arthritis pathophysiology and implications for therapy. N Engl J Med 322:1277-1289, 1990
2. Laskin RS: Total condylar knee replacement in patients who have rheumatoid arthritis. J Bone Joint Surg [Am] 72:529-535, 1990
3. Panayi GS: The second international symposium on the immunotherapy of rheumatic diseases: concepts and an overview. Clin Exp Rheumatol 11 (suppl 8):S1-S3, 1993
4. Sigal LH, Johnston SL, Philips PE: Cellular immune responses to cartilage components in rheumatoid arthritis and osteoarthritis: a review and report of a study. Clin Exp Rheumatol 6:59-66, 1988
5. Glant TT, Fulop C, Mikecz K, Buzas E, Molnar G, Erhardt P: Proteoglycan-specific autoreactive antibodies and T-lymphocytes in experimental arthritis and human rheumatoid joint diseases, Biochem Soc Trans 18:796-799, 1990
6. Alsalameh S, Mollenhauer J, Hain N, Stock K-P, Kalden JR, Burmester GR: Cellular immune responses toward human articular chondrocytes. Arthritis Rheum 33:1477-1486, 1990
7. Nelson JL, Hansen JA, Singal D, Buchanan W, Marshall W, Larsen B, Feng L, Feng CH, Thomson W, Ollier W, Howell W, Smith J, Eliaou JF, Clot J, Taneja V, Mehra N, Naik S, Agarwal G, Angelini G, Ferrara G, Delfino L, Morozzi G, Marcolongo R, Tsuchiya K, Sasazuki T, Chandanayingyong D, Charoenwongse P, Deesomchok U, Templin D, Sartakova M, Konenkov V: Rheumatoid arthritis. In, Proceedings of the Eleventh International Histocompatibility Workshop and Conference. Vol. 1. Edited by K Tsuji, M Aizawa, T Sasazuki. Oxford, Oxford University Press, 1991
8. Gregerson PK, Silver J, Winchester RJ: The shared epitope hypothesis: an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum 30:1205-1213, 1987
9. Hakala BE, White C, Recklies A: Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family. J Biol Chem 268:25803-25810, 1993
10. Hammer J, Valsasnini P, Tolba K, Bolin D, Higelin J, Takacs B, Sinigaglia F: Promiscuous and allele-specific anchors in HLA-DR-binding peptides. Cell 74:197-203, 1993
11. Chicz RM, Urban RG, Gorga JC, Vignali DAA, Lane WS, Strominger JL: Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles. J Exp Med 178:27-47, 1993
12. Sette A, Sidney J, Oseroff C, Del Guercio MF, Southwood S, Arrhenius T, Powell MF, Colon SM, Gaeta FCA, Grey HM: HLA DR4w4-binding motifs illustrate the biochemical basis of degeneracy and specificity in peptide-DR interactions. J Immunol 151:3163-3170, 1993
13. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS, Medsger TA Jr, Mitchell DM, Neustadt DH, Finals RS, Schaller JG, Sharp JT, Wilder RL, Hunder GG: The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31:315-324, 1988
14. Steinbrocker O, Traeger CH, Batterman RC: Therapeutic criteria in rheumatoid arthritis. JAMA 140:659-662, 1949
15. Goodacre JA, Middleton S, Lynn S, Ross DA, Pearson J: Human cartilage aggrecan CS1 region contains cryptic T-cell recognition sites. Immunology 78:586-591, 1993
16. Joosten I, Wauben MHM, Holewijn MC, Reske K, Pederson LO, Roosenboom CFP, Hensen EJ, van Eden W, Buus S: Direct binding of autoimmune disease related T-cell epitopes to purified Lewis rat MHC class II molecules. Int Immunol 6:751-759, 1994
17. Nag B, Deshpande SV, Clark BR: Novel methods to rapidly and sensitively analyze antigenic peptide binding to MHC class II molecules. J Immunol Methods 142:105-111, 1991
18. Yang SY, Milford E, Hämmerling U, Dupont B: Description of the reference panel of B-lymphoblastoid cell lines for factors of the HLA system: the B cell line panel for the tenth international histocompatibility workshop. In, Immunobiology of HLA. Vol. 1. Edited by B Dupont. New York, Springer Verlag, 1989
19. Johansen JS, Jensen HS, Price PA: A new biochemical marker for joint injury: analysis of YKL-40 in serum and synovial fluid. Br J Rheumatol 32:949-955, 1993
20. Nyirkos P, Golds EE: Human synovial cells secrete a 39 kDa protein similar to a bovine mammary protein expressed during the non-lactating period. J Biochem 268:265-268, 1990
21. Giant TT, Mikecz K, Arzoumanian A, Poole AR: Proteoglycan-induced arthritis in BALB/c mice: clinical features and histopathology. Arthritis Rheum 30:201-212, 1987
22. Metzler B, Wraith DC: Inhibition of experimental autoimmune encephalomyelitis by inhalation but not oral administration of the encephalitogenic peptide: influence of MHC binding affinity. Int Immunol 5:1159-1165, 1993
23. Brown JH, Jardetsky TS, Gorga JC, Stern LJ, Urban RG, Strominger JL, Wiley DC: 3-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature 364:33-39, 1993
24. Stern LJ, Brown JH, Jardetzky TS, Gorga JC, Urban RG, Strominger JL, Wiley DC: Crystal structure of the human class II MHC protein HLA-DR1 completed with an influenza virus peptide. Nature 368:215-221, 1994
25. Sorg RJ, Enczmann J, Sorg U, Heermeier K, Schneider EM, Wernet P: Rapid and sensitive mRNA phenotyping for interleukins (IL-1 to IL-6) and colony-stimulating factors (G-CSF, M-CSF, and GM-CSF) by reverse transcription and subsequent polymerase chain reaction. Exp Hematol 19:882-887, 1991
26. Miltenburg AM, van Laar JM, dc Kuiper R, Dana MR, Breedveld FC: T cells cloned from human rheumatoid synovial membrane functionally represent the Th1 subset. Scand J Immunol 35:603-610, 1992
27. Quayle AJ, Chomarat P, Miossec P, Kjeldsen-Kragh J, Forre O, Natvig JB: Rheumatoid inflammatory T-cell clones express mostly Th1 but also Th2 and mixed (Th0-like) cytokine patterns, Scand J Immunol 38:75-82, 1993
28. Simon AK, Seipelt E, Sieper J: Divergent T cell cytokine patterns in inflammatory arthritis. Proc Natl Acad Sci USA 91:8562-8566, 1994
29. Courtenay JS, Dallman MJ, Dayan AD, Martin A, Mosedale B: Immunisation against heterologous type II collagen induces arthritis in mice. Nature 283:666-668, 1980
30. Gao X, Olsen NJ, Pincus T, Stastny P: HLA-DR alleles with naturally occurring amino acid substitutions and risk for development of rheumatoid arthritis. Arthritis Rheum 33:939-946, 1990
31. Ota K, Marsui M, Milford EL, Mackin GA, Weiner HL, Hafler DA: T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature 346:183-187, 1990
32. Van Noort JM, van Sechel AC, Bajrumovic JJ, El Ouagmiri M, Polman CH, Lassmann H, Ravid R: The small heat shock protein alpha B-crystallin as candidate autoantigen in multiple sclerosis. Nature 375:798-801, 1995
33. Sercarz EE, Lehmann PV, Ametani A, Benichou G, Miller A, Moudgil K: Dominance and crypticity of T cell antigenic determinants. Annu Rev Immunol 11:729-766, 1993
34. Struyk L, Hawes GE, Chatila MK, Breedveld FC, Kurnick JT, van den Elsen PJ: T cell receptors in rheumatoid arthritis. Arthritis Rheum 38:577-589, 1995
35. Howell MD, Dively JP, Lundeen A, Esty A, Winters ST, Carlo DJ, Brostoff SW: Limited T-cell receptor β-chain heterogeneity among interleukin 2 receptor-positive synovial cells suggests a role for superantigen in rheumatoid arthritis. Proc Natl Acad Sci USA 88:10921-10925, 1991
36. Elson CJ, Barker RN, Thompson SJ, Williams NA: Immunologically ignorant autoreactive T cells, epitope spreading and repertoire limitation. Immunol Today 16:71-76, 1995