-
1
-
-
0036734653
-
Regulation of focal adhesion kinase by a novel protein inhibitor FIP200
-
Abbi S, Ueda H, Zheng C, et al. Regulation of focal adhesion kinase by a novel protein inhibitor FIP200. Mol Biol Cell 2002;13:3178-91.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 3178-3191
-
-
Abbi, S.1
Ueda, H.2
Zheng, C.3
-
2
-
-
0037193678
-
Isolation, characterization and mapping of the mouse and human RB1CC1 genes
-
Chano T, Ikegawa S, Saito-Ohara F, et al. Isolation, characterization and mapping of the mouse and human RB1CC1 genes. Gene 2002;291:29-34.
-
(2002)
Gene
, vol.291
, pp. 29-34
-
-
Chano, T.1
Ikegawa, S.2
Saito-Ohara, F.3
-
3
-
-
0031889817
-
Multiple sites of loss of heterozygosity on chromosome 8 in human breast cancer has differential correlation with clinical parameters
-
Dahiya R, Perinchery G, Deng G, Lee C. Multiple sites of loss of heterozygosity on chromosome 8 in human breast cancer has differential correlation with clinical parameters. Int J Oncol 1998;12:811-6.
-
(1998)
Int J Oncol
, vol.12
, pp. 811-816
-
-
Dahiya, R.1
Perinchery, G.2
Deng, G.3
Lee, C.4
-
4
-
-
85047696381
-
Identification of RB1CC1, a novel human gene that can induce RB1 in various human cells
-
Chano T, Ikegawa S, Kontani K, Okabe H, Baldini N, Saeki Y. Identification of RB1CC1, a novel human gene that can induce RB1 in various human cells. Oncogene 2002;21:1295-8.
-
(2002)
Oncogene
, vol.21
, pp. 1295-1298
-
-
Chano, T.1
Ikegawa, S.2
Kontani, K.3
Okabe, H.4
Baldini, N.5
Saeki, Y.6
-
5
-
-
0036648240
-
Truncating mutations of RB1CC1 in human breast cancer
-
Chano T, Kontani K, Teramoto K, Okabe H, Ikegawa S. Truncating mutations of RB1CC1 in human breast cancer. Nat Genet 2002;31:285-8.
-
(2002)
Nat Genet
, vol.31
, pp. 285-288
-
-
Chano, T.1
Kontani, K.2
Teramoto, K.3
Okabe, H.4
Ikegawa, S.5
-
6
-
-
0031951182
-
Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes
-
Lundberg AS, Weinberg RA Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes. Mol Cell Biol 1998;18:753-61.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 753-761
-
-
Lundberg, A.S.1
Weinberg, R.A.2
-
8
-
-
0033564697
-
CDK inhibitors: Positive and negative regulators of Gj-phase progression
-
Sherr CJ, Roberts JM. CDK inhibitors: positive and negative regulators of Gj-phase progression. Genes Dev 1999;13:1501-12.
-
(1999)
Genes Dev
, vol.13
, pp. 1501-1512
-
-
Sherr, C.J.1
Roberts, J.M.2
-
9
-
-
0034738420
-
P21 WAF1/CIP1: More than a break to the cell cycle?
-
Dotto GP. p21 WAF1/CIP1: more than a break to the cell cycle? Biochim Biophys Acta 2000;1471:M43-56.
-
(2000)
Biochim Biophys Acta
, vol.1471
-
-
Dotto, G.P.1
-
10
-
-
0031909865
-
p53-dependent elevation of p2Wafl expression by UV light is mediated through mRNA stabilization and involves a vanadate-sensitive regulatory system
-
Gorospe M, Wang X, Holbrook NJ. p53-dependent elevation of p2]Wafl expression by UV light is mediated through mRNA stabilization and involves a vanadate-sensitive regulatory system. Mol Cell Biol 1998;18:1400-7.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 1400-1407
-
-
Gorospe, M.1
Wang, X.2
Holbrook, N.J.3
-
11
-
-
0030658965
-
CCAAT/enhancer binding protein α regulates p21 protein and hepatocyte proliferation in newborn mice
-
Timchenko NA, Harris TE, Wilde M. et al. CCAAT/enhancer binding protein α regulates p21 protein and hepatocyte proliferation in newborn mice. Mol Cell Biol 1997;17:7353-61.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 7353-7361
-
-
Timchenko, N.A.1
Harris, T.E.2
Wilde, M.3
-
12
-
-
0032514283
-
Uncoupling of p21WAF1/CIP1/CDI1 mRNA and protein expression upon genotoxic sress
-
Butz K, Geisen C, Ullmann A, Zentgraf H, Hoppe-Seyler F. Uncoupling of p21WAF1/CIP1/CDI1 mRNA and protein expression upon genotoxic sress. Oncogene 1998;17:781-7.
-
(1998)
Oncogene
, vol.17
, pp. 781-787
-
-
Butz, K.1
Geisen, C.2
Ullmann, A.3
Zentgraf, H.4
Hoppe-Seyler, F.5
-
13
-
-
0033080402
-
Transcriptional regulation of the p21WAF1/CIP1 gene
-
Gartel AL, Tyner AL. Transcriptional regulation of the p21WAF1/CIP1 gene. Exp Cell Res 1999;246:280-9.
-
(1999)
Exp Cell Res
, vol.246
, pp. 280-289
-
-
Gartel, A.L.1
Tyner, A.L.2
-
14
-
-
0000226650
-
Association of focal adhesion kinase with Grb7 and its role in cell migration
-
Han DC, Guan JL. Association of focal adhesion kinase with Grb7 and its role in cell migration. J Biol Chem 1999;274:24425-30.
-
(1999)
J Biol Chem
, vol.274
, pp. 24425-24430
-
-
Han, D.C.1
Guan, J.L.2
-
15
-
-
0034678330
-
Suppression of Pyk2 kinase and cellular activities by FIP200
-
Ueda H, Abbi S, Zheng C, Guan JL. Suppression of Pyk2 kinase and cellular activities by FIP200. J Cell Biol 2000;149:423-30.
-
(2000)
J Cell Biol
, vol.149
, pp. 423-430
-
-
Ueda, H.1
Abbi, S.2
Zheng, C.3
Guan, J.L.4
-
16
-
-
0037117550
-
A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
-
Sui G, Soohoo C, Affar EB, et al. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc Natl Acad Sci U S A 2002;99: 5515-20.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 5515-5520
-
-
Sui, G.1
Soohoo, C.2
Affar, E.B.3
-
17
-
-
1542304700
-
Focal adhesion kinase regulation of N-WASP subcellular localization and function
-
Wu X, Suetsugu S, Cooper LA, Takenawa T, Guan JL. Focal adhesion kinase regulation of N-WASP subcellular localization and function. J Biol Chem 2004;279: 9565-76.
-
(2004)
J Biol Chem
, vol.279
, pp. 9565-9576
-
-
Wu, X.1
Suetsugu, S.2
Cooper, L.A.3
Takenawa, T.4
Guan, J.L.5
-
18
-
-
0036671883
-
Estradiol stabilizes p53 protein in breast cancer cell line, MCF-7
-
Oknmura N, Saji S, Eguchi H, Hayashi S, Saji S, Nakashima S. Estradiol stabilizes p53 protein in breast cancer cell line, MCF-7. Jpn J Cancer Res 2002;93:867-73.
-
(2002)
Jpn J Cancer Res
, vol.93
, pp. 867-873
-
-
Oknmura, N.1
Saji, S.2
Eguchi, H.3
Hayashi, S.4
Saji, S.5
Nakashima, S.6
-
19
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997;88:329-31.
-
(1997)
Cell
, vol.88
, pp. 329-331
-
-
Levine, A.J.1
-
20
-
-
0037370357
-
Stabilization of p53 by CP-31398 inhibits ubiquitination without altering phosphorylation at Serine 15 or 20 or MDM2 binding
-
Wang W, Takimoto R, Rastinejad F, El-Deiry WS. Stabilization of p53 by CP-31398 inhibits ubiquitination without altering phosphorylation at Serine 15 or 20 or MDM2 binding. Mol Cell Biol 2003;23:2171-81.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 2171-2181
-
-
Wang, W.1
Takimoto, R.2
Rastinejad, F.3
El-Deiry, W.S.4
-
21
-
-
7244238177
-
Inhibition of MDM2-mediated p53 ubiqutination and degradation by ribosomal protein L5
-
Dai MS, Lu H. Inhibition of MDM2-mediated p53 ubiqutination and degradation by ribosomal protein L5. J Biol Chem 2004;279:44475-82.
-
(2004)
J Biol Chem
, vol.279
, pp. 44475-44482
-
-
Dai, M.S.1
Lu, H.2
-
22
-
-
0033598354
-
p53-dependent apoptosis or growth arrest induced by different forms of radiation in U2OS cells: p21WAF1/CIP1 repression in UV induced apoptosis
-
Allan LA, Fried M. p53-dependent apoptosis or growth arrest induced by different forms of radiation in U2OS cells: p21WAF1/CIP1 repression in UV induced apoptosis. Oncogene 1999;18:5403-12.
-
(1999)
Oncogene
, vol.18
, pp. 5403-5412
-
-
Allan, L.A.1
Fried, M.2
-
23
-
-
0042415612
-
Nuclear and cytoplasmic degradation of endogenous p53 and HDM2 occurs during down-regufation of the p53 response after multiple types of DNA damage
-
Joseph TW, Zaika A, Moll UM. Nuclear and cytoplasmic degradation of endogenous p53 and HDM2 occurs during down-regufation of the p53 response after multiple types of DNA damage. FASEB J 2003;17:1622-30.
-
(2003)
FASEB J
, vol.17
, pp. 1622-1630
-
-
Joseph, T.W.1
Zaika, A.2
Moll, U.M.3
-
24
-
-
2342447397
-
The ubiquitin ligase COP1 is a critical negative regulator of p53
-
Dornan D, Wertz I, Shimizu H, et al. The ubiquitin ligase COP1 is a critical negative regulator of p53. Nature 2004;429:86-92.
-
(2004)
Nature
, vol.429
, pp. 86-92
-
-
Dornan, D.1
Wertz, I.2
Shimizu, H.3
-
26
-
-
0032931517
-
The p53 pathway
-
Prives C, Hall PA. The p53 pathway. J Pathol 1999; 187:112-26.
-
(1999)
J Pathol
, vol.187
, pp. 112-126
-
-
Prives, C.1
Hall, P.A.2
-
27
-
-
0036145018
-
Multiple roles of the tumor suppressor p53
-
Bargonetti J, Manfredi JJ. Multiple roles of the tumor suppressor p53. Curr Opin Oncol 2002;14:86-91.
-
(2002)
Curr Opin Oncol
, vol.14
, pp. 86-91
-
-
Bargonetti, J.1
Manfredi, J.J.2
-
28
-
-
0037329056
-
The p53-Mdm2 module and the ubiquitin system
-
Michael D, Oren M. The p53-Mdm2 module and the ubiquitin system. Semin Cancer Biol 2003;13: 49-58.
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 49-58
-
-
Michael, D.1
Oren, M.2
-
29
-
-
0031583962
-
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
-
Honda R, Tanaka H, Yasuda H. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett 1997;420:25-7.
-
(1997)
FEBS Lett
, vol.420
, pp. 25-27
-
-
Honda, R.1
Tanaka, H.2
Yasuda, H.3
-
30
-
-
0034708458
-
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
-
Fang S, Jensen JR Ludwig RL, Vousden KH, Weissman AM. Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53. J Biol Chem 2000;275: 8945-51.
-
(2000)
J Biol Chem
, vol.275
, pp. 8945-8951
-
-
Fang, S.1
Jensen, J.R.2
Ludwig, R.L.3
Vousden, K.H.4
Weissman, A.M.5
-
31
-
-
0031014946
-
Proteolytic cleavage of human p53 by calpain: A potential regulator of protein stability
-
Kubbutat MH, Vousden KH. Proteolytic cleavage of human p53 by calpain: a potential regulator of protein stability. Mol Cell Biol 1997;17:460-8.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 460-468
-
-
Kubbutat, M.H.1
Vousden, K.H.2
-
32
-
-
0037050257
-
Restoration of p53 expression sensitizes papillomavirus type 16 immortalized human keratinocytes to CD95-mediated apoptosis
-
Aguilar-Lemarroy A, Gariglio P, Whitaker NJ, et al. Restoration of p53 expression sensitizes papillomavirus type 16 immortalized human keratinocytes to CD95-mediated apoptosis. Oncogene 2002;21:165-75.
-
(2002)
Oncogene
, vol.21
, pp. 165-175
-
-
Aguilar-Lemarroy, A.1
Gariglio, P.2
Whitaker, N.J.3
-
33
-
-
0036791010
-
Mdm-2 and ubiquitin-independent p53 proteasomal degradation regulated by NQO1
-
Asher G, Lotem J, Sachs L, Kahana C, Shaul Y. Mdm-2 and ubiquitin-independent p53 proteasomal degradation regulated by NQO1. Proc Natl Acad Sci U S A 2002; 99:13125-30.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 13125-13130
-
-
Asher, G.1
Lotem, J.2
Sachs, L.3
Kahana, C.4
Shaul, Y.5
-
34
-
-
0037022582
-
NQO1 stabilized p53 through a distinct pathway
-
Asher G, Lotem J, Kama R, Sachs L, Shaul Y. NQO1 stabilized p53 through a distinct pathway. Proc Natl Acad Sci U S A 2002;99:3099-104.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 3099-3104
-
-
Asher, G.1
Lotem, J.2
Kama, R.3
Sachs, L.4
Shaul, Y.5
-
35
-
-
13244275245
-
A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73
-
Asher G, Tsvetkov P. Kahana C, Shaul Y. A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73. Genes Dev 2005;19:316-21.
-
(2005)
Genes Dev
, vol.19
, pp. 316-321
-
-
Asher, G.1
Tsvetkov, P.2
Kahana, C.3
Shaul, Y.4
-
36
-
-
0037100740
-
Targeting the cell cycle for cancer therapy
-
Carnero A. Targeting the cell cycle for cancer therapy. Br J Cancer 2002;87:129-33.
-
(2002)
Br J Cancer
, vol.87
, pp. 129-133
-
-
Carnero, A.1
-
38
-
-
0033578816
-
Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G
-
Harbour JW, Luo RX, Santi AD, Postigo AA, Dean DC. Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G,. Cell 1999;98:859-69.
-
(1999)
Cell
, vol.98
, pp. 859-869
-
-
Harbour, J.W.1
Luo, R.X.2
Santi, A.D.3
Postigo, A.A.4
Dean, D.C.5
-
40
-
-
0031877301
-
c-Myc or cyclin D1 mimics estrogen effects on cyclin E/Cdk2 activation and cell cycle reentry
-
Prall OW, Rogan EM, Musgrove EA, Watts CK, Sutherland RL. c-Myc or cyclin D1 mimics estrogen effects on cyclin E/Cdk2 activation and cell cycle reentry. Mol Cell Biol 1998;18:4499-508.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 4499-4508
-
-
Prall, O.W.1
Rogan, E.M.2
Musgrove, E.A.3
Watts, C.K.4
Sutherland, R.L.5
-
41
-
-
0035280982
-
Phosphorylation of serine 15 and 37 is necessary for efficient accumulation of p53 following irradiation with UV
-
Bean LJ, Stark GR. Phosphorylation of serine 15 and 37 is necessary for efficient accumulation of p53 following irradiation with UV. Oncogene 2001;20: 1076-84.
-
(2001)
Oncogene
, vol.20
, pp. 1076-1084
-
-
Bean, L.J.1
Stark, G.R.2
-
44
-
-
0032169459
-
JNK targets p53 ubiquitination and degradation in noastressed cells
-
Fuchs SY, Adler V, Buschmann T, et al. JNK targets p53 ubiquitination and degradation in noastressed cells. Genes Dev 1998;12:2658-63.
-
(1998)
Genes Dev
, vol.12
, pp. 2658-2663
-
-
Fuchs, S.Y.1
Adler, V.2
Buschmann, T.3
-
46
-
-
0037459377
-
Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation
-
Leng RP, Lin Y, Ma W, et al. Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation. Cell 2003;112:779-91.
-
(2003)
Cell
, vol.112
, pp. 779-791
-
-
Leng, R.P.1
Lin, Y.2
Ma, W.3
-
47
-
-
0034824495
-
p300/CBP/p53 interaction and regulation of the p53 response
-
Grossman SR. p300/CBP/p53 interaction and regulation of the p53 response. Eur J Biochem 2001;268: 2773-8.
-
(2001)
Eur J Biochem
, vol.268
, pp. 2773-2778
-
-
Grossman, S.R.1
|