p53-Dependent elevation of p21(WAF1) expression by UV light is mediated through mRNA stabilization and involves a vanadate-sensitive regulatory system

Molecular and Cellular Biology

Volumn 18, Issue 3, 1998, Pages 1400-1407

  Gorospe, Myriam ^a   Wang, Xiantao ^a   Holbrook, Nikki J ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MIMOSINE; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PROTEIN TYROSINE KINASE; VANADIC ACID;

AMINO ACID SEQUENCE; ARTICLE; CELL SURVIVAL; COLORECTAL CARCINOMA; ENZYME ACTIVITY; GENE EXPRESSION; MAMMAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; TRANSCRIPTION REGULATION; ULTRAVIOLET RADIATION;

EID: 0031909865     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.18.3.1400     Document Type: Article

References (49)

1. Akashi, M., M. Hachiya, Y. Osawa, K. Spirin, G. Suzuki, and H. P. Koeffler. 1995. Irradiation induces Waf1 expression through a p53-independent pathway in KG-1 cells. J. Biol. Chem. 270:19181-19187.
2. Waf1/CIP1/SDI1 is elevated through a p53-independent pathway by mimosine. Cell Growth Differ. 7:893-901.
3. Chen, Y. R., X. Wang, R. J. Templeton, R. J. Davis, and T. H. Tan. 1996. The role or c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation. J. Biol. Chem. 271:31929-31936.
4. Church, G. M., and W. Gilbert. 1984. Genomic sequencing. Proc. Natl. Acad. Sci. USA 81:1991-1995.
5. Decker, C. J., and R. Parker. 1995. Diversity of cytoplasmic functions for the 3′ untranslated region of eukaryotic transcripts. Curr. Opin. Cell Biol. 7:386-392.
6. DeFrank, J. S., W. Tang, and S. N. Powell. 1996. p53-null cells are more sensitive to ultraviolet light only in the presence of caffeine. Cancer Res. 56:5365-5368.
7. CIP1/Waf1 undergo normal development, but are defective in G1 checkpoint control. Cell 82:675-684.
8. El-Deiry, W. S., T. Tokino, T. Velculescu, D. B. Levy, R. Parsons, J. M. Trent, D. Lin, W. E. Mercer, K. W. Kinzler, and B. Vogelstein. 1993 Waf1, a potential mediator of p53 tumor suppression. Cell 75:817-825.
9. Ewen, M. E., C. J. Oliver, H. K. Sluss, S. J. Miller, and D. S. Peeper. 1995. p53-dependent repression of CDK4 translation in TGF-β-induced G1 cell cycle arrest. Genes Dev. 9:204-217.
10. Gao, F. B., C. C. Carson, T. Levine, and J. D. Keene. 1994. Selection of a subset of mRNAs from combinatorial 3′ untranslated region libraries using the neuronal RNA-binding protein Hel-N1. Proc. Natl. Acad. Sci. USA 91:11207-11211.
11. Gillis, P., and J. S. Malter. 1991. The adenosine-uridine binding factor recognizes the AU-rich elements of cytokine, lymphokine and oncogene mRNAs. J. Biol. Chem. 266:3172-3177.
12. Good, P. J. 1995. A conserved family of elav-like genes in vertebrates. Proc. Natl. Acad. Sci. USA 92:4557-4561.
13. Gorospe, M., S. Kumar, and C. Baglioni. 1993. Tumor necrosis factor increases stability of interleukin-1 mRNA by activating protein kinase C. J. Biol. Chem. 268:6214-6220.
14. Gorospe, M., and C. Baglioni. 1994. Degradation of unstable interleukin-1 alpha mRNA in a rabbit reticulocyte cell-free system. Localization of an instability determinant to a cluster of AUUUA motifs. J. Biol. Chem. 269:11845-11851.
15. 2-mediated cellular arrest and death. Cancer Res. 56:475-479.
16. CIP1/Waf1 expression by cellular stress: p53-dependent and p53-independent mechanisms. Mol. Cell. Differ. 4:47-65.
17. 2-mediated apoptosis of human colorectal carcinoma cells. Mol. Cell. Biol. 16:6654-6660.
18. Waf1/Cip1 expression prevents p53-mediated apoptotic cell death of human melanoma cells. Oncogene 14:929-935.
19. Gotz, C., and M. Montenarh. 1995. p53 and its implications in apoptosis. Int. J. Oncol. 6:1129-1135.
20. Groudine, M., M. Peretz, and H. Weintraub. 1981. Transcriptional regulation of hemoglobin switching in chicken embryos. Mol. Cell. Biol. 1:281-288.
21. Gupta, S., D. Campbell, B. Derijard, and R. J. Davis. 1995. Transcription factor ATF2 regulation by the JNK signal transduction. Science 267:389-393.
22. Holbrook, N. J., Y. Liu, and A. J. Fornace, Jr. 1996. Signaling events controlling the molecular response to genotoxic stress. EXS 77:273-288.
23. Hunter, T., and M. Karin. 1992. The regulation of transcription by phosphorylation. Cell 70:375-387.
24. Huppi, K., D. Siwarski, J. Dosik, P. Michieli, M. Chedid, S. Reed, B. Mock, D. Givol, and J. F. Mushinski. 1994. Molecular cloning, sequencing, chromosomal localization and expression of mouse p21 (Waf1). Oncogene 9:3017-3020.
25. Iordanov, M., K. Bender, T. Ade, W. Schmid, C. Sachsenmaier, K. Engel, M. Gaestel, H. J. Rahmsdorf, and P. Herrlich. 1997. CREB is activated by UVC through a p38/HOG1-dependent protein kinase. EMBO J. 16:1009-1022.
26. Jackman, J., I. J. Alamo, and A. J. Fornace, Jr. 1994. Genotoxic stress confers preferential and coordinate messenger RNA stability on the five gadd genes. Cancer Res. 54:5656-5662.
27. Johnson, M., D. Dimitrov, P. J. Vojta, J. C. Barret, A. Noda, O. M. Pereira-Smith, and J. R. Smith. 1994. Evidence for a p53-independent pathway for upregulation of SDI1/CIP1/Waf1/p21 RNA in human cells. Mol. Carcinog. 11:59-64.
28. Kessis, T. D., R. J. Slebos, W. D. Nelson, M. B. Kastan, B. S. Plunkett, S. M. Han, A. T. Lorincz, L. Hedrick, and K. R. Cho. 1993. Human papilloma virus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage. Proc. Natl. Acad. Sci. USA 90:3988-3992.
29. Kyriakis, J. M., and J. Avruch. 1997. Protein kinase cascades activated by stress and inflammatory cytokines. Bioessays 18:567-577.
30. Lee, J. C., and P. R. Young. 1996. Role of CSB/p38/RK stress response kinase in LPS and cytokine signaling mechanisms. J. Leukocyte Biol. 59:152-157.
31. Waf1/CIP1 expression through mitogen-activated protein kinase signaling pathway. Cancer Res. 56:1-5.
32. Lowe, S. W., H. E. Ruley, T. Jacks, and D. E. Housman. 1993. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74:957-967.
33. Ma, W. J., S. Cheng, C. Campbell, A. Wright, and H. Furneaux. 1996. Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein. J. Biol. Chem. 271:8144-8151.
34. Malter, J. S., and Y. Hong. 1991. A redox switch and phosphorylation are involved in the post-translational up-regulation of the adenosine-uridine binding factor by phorbol ester and ionophore. J. Biol. Chem. 266:3167-3171.
35. Michieli, P., M. Chedid, D. Lin, J. H. Pierce, W. E. Mercer, and D. Givol. 1994. Induction of Waf1/CIP1 by a p53-independent pathway. Cancer Res. 54:3391-3395.
36. Murphy, M., A. Hinman, and A. J. Levine. 1996. Wild-type p53 negatively regulates the expression of a microtubule-associated protein. Genes Dev. 10:2971-2980.
37. Waf1 is required for survival of differentiating neuroblastoma cells. Mol. Cell. Biol. 16:1335-1341.
38. Price, M. A., F. H. Cruzalegui, and R. Treisman. 1996. The p38 and ERK MAP kinase pathways cooperate to activate ternary complex factors and c-fos transcription in response to UV light. EMBO J. 15:6552-6563.
39. Rondon, I. J., L. A. MacMillan, B. S. Beckman, M. A. Goldberg, T. Schneider, H. F. Bunn, and J. S. Malter. 1991. Hypoxia up-regulates the activity of a novel erythropoietin mRNA binding protein. J. Biol. Chem. 266:16594-16589.
40. Russo, T., N. Zambrano, F. Esposito, R. Ammendola, F. Cimino, M. Fiscella, J. Jackman, P. M. O'Connor, C. W. Anderson, and E. Appella. 1995. A p53-independent pathway for activation of Waf1/CIP1 expression following oxidative stress. J. Biol. Chem. 270:29386-29391.
41. Shaw, G., and R. Kamen. 1986. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46:659-667.
42. Waf1/Cip1/Sdi1 in cell death and DNA repair as studied using a tetracycline-inducible system in p53-deficient cells. Oncogene 14:1875-1882.
43. Smith, M. L., I.-T. Chen, Q. Zhan, P. M. O'Connor, and A. J. Fornace, Jr. 1995. Involvement of the p53 tumor suppressor in repair of U.V.-type DNA damage. Oncogene 9:1053-1059.
44. Thivierge, M., J. L. Parent, J. Stankova, and M. Rola-Pleszczynski. 1996. Modulation of human platelet-activating factor receptor gene expression by protein kinase C activation. J. Immunol. 157:4681-1687.
45. Tyrrell, R. M. 1996. UV activation of mammalian stress proteins. EXS 77:255-271.
46. Tyrrell, R. M. 1996. Activation of mammalian gene expression by the UV component of sunlight - from models to reality. Bioessays 18:139-148.
47. Waldman, T., C. Lengauer, K. W. Kinzler, and B. Vogelstein. 1996. Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 381:713-716.
48. Woodgett, J. R., J. Avruch, and J. Kyriakis. 1996. The stress-activated protein kinase pathway. Cancer Surv. 27:127-138.
49. Zanke, B. W., K. Boudreau, E. Rubie, E. Winnett, L. A. Tibbles, L. Zon, J. Kyriakis, F. F. Liu, and J. R. Woodgett. 1996. The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat. Curr. Biol. 6:606-613.