Structure of the BgK-Kv1.1 Complex based on distance restraints identified by double mutant cycles: Molecular basis for convergent evolution of Kv1 channel blockers

Journal of Biological Chemistry

Volumn 277, Issue 40, 2002, Pages 37406-37413

  Gilquin, Bernard ^a   Racapé, Judith ^b   Wrisch, Anja ^a   Visan, Violeta ^a   Lecoq, Alain ^a   Grissmer, Stephan ^a   Ménez, André ^a   Gasparini, Sylvaine ^a  

^a CEA SACLAY   (France)

^b UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROSTATICS; OXYGEN; POTASSIUM;

CONVERGENT BINDING SOLUTIONS;

BIOCHEMISTRY;

AMINO ACID; CARBONYL DERIVATIVE; LYSINE; OXYGEN; POTASSIUM CHANNEL; PROTEIN BGK KV1 1; SEA ANEMONE TOXIN; SOLVENT; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ATOM; BINDING SITE; CONTROLLED STUDY; DATA ANALYSIS; HYDROPHOBICITY; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RAT;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CNIDARIAN VENOMS; KV1.1 POTASSIUM CHANNEL; MEMBRANE POTENTIALS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RATS; SEA ANEMONES; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

ACTINIARIA; ANEMONE; ANIMALIA; SCORPIONES;

EID: 0037020077     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M206205200     Document Type: Article

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