Interaction of agitoxin2, charybdotoxin, and iberiotoxin with potassium channels: Selectivity between voltage-gated and Maxi-K channels

Proteins: Structure, Function and Genetics

Volumn 52, Issue 2, 2003, Pages 146-154

  Gao, Ying Duo ^a   Garcia, Maria L ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

AgTX2; Binding; ChTX; IbTX; Maxi K channel; Molecular modeling; Mutagenesis; Peptides; Shaker channels

Indexed keywords

AGITOXIN 2; CALCIUM ACTIVATED POTASSIUM CHANNEL; CHARYBDOTOXIN; IBERIOTOXIN; PEPTIDE; POTASSIUM CHANNEL; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

ARTICLE; CRYSTAL STRUCTURE; HYDROGEN BOND; KCSA CHANNEL; LARGE CONDUCTANE CALCIUM CHANNEL; MAXI POTASSIUM CHANNEL; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN INTERACTION; SEQUENCE HOMOLOGY; SHAKER TYPE VOLTAGE GATED POTASSIUM CHANNEL; VESTIBULE;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CHARYBDOTOXIN; HYDROGEN BONDING; KV1.3 POTASSIUM CHANNEL; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN BINDING; PROTEIN SUBUNITS; SCORPION VENOMS; SEQUENCE ALIGNMENT; TOXINS, BIOLOGICAL;

BACTERIA (MICROORGANISMS);

EID: 0037999227     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.10341     Document Type: Article

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