-
1
-
-
0025613812
-
Linkage of early-onset familial breast cancer to chromosome 17q21
-
J.M. Hall, M.K. Lee, B. Newman, J.E. Morrow, L.A. Anderson, and B. Huey Linkage of early-onset familial breast cancer to chromosome 17q21 Science 250 4988 1990 1684 1689
-
(1990)
Science
, vol.250
, Issue.4988
, pp. 1684-1689
-
-
Hall, J.M.1
Lee, M.K.2
Newman, B.3
Morrow, J.E.4
Anderson, L.A.5
Huey, B.6
-
2
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
Y. Miki, J. Swensen, D. Shattuck-Eidens, P.A. Futreal, K. Harshman, and S. Tavtigian A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1 Science 266 5182 1994 66 71
-
(1994)
Science
, vol.266
, Issue.5182
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
Futreal, P.A.4
Harshman, K.5
Tavtigian, S.6
-
3
-
-
0027433563
-
Genetic linkage analysis in familial breast and ovarian cancer: Results from 214 families. the Breast Cancer Linkage Consortium
-
D.F. Easton, D.T. Bishop, D. Ford, and G.P. Crockford Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium Am. J. Hum. Genet. 52 4 1993 678 701
-
(1993)
Am. J. Hum. Genet.
, vol.52
, Issue.4
, pp. 678-701
-
-
Easton, D.F.1
Bishop, D.T.2
Ford, D.3
Crockford, G.P.4
-
4
-
-
0028073794
-
BRCA1 mutations in primary breast and ovarian carcinomas
-
P.A. Futreal, Q. Liu, D. Shattuck-Eidens, C. Cochran, K. Harshman, and S. Tavtigian BRCA1 mutations in primary breast and ovarian carcinomas Science 266 5182 1994 120 122
-
(1994)
Science
, vol.266
, Issue.5182
, pp. 120-122
-
-
Futreal, P.A.1
Liu, Q.2
Shattuck-Eidens, D.3
Cochran, C.4
Harshman, K.5
Tavtigian, S.6
-
5
-
-
0028960025
-
Somatic mutations in the BRCA1 gene in sporadic ovarian tumours
-
S.D. Merajver, T.M. Pham, R.F. Caduff, M. Chen, E.L. Poy, and K.A. Cooney Somatic mutations in the BRCA1 gene in sporadic ovarian tumours Nat. Genet. 9 4 1995 439 443
-
(1995)
Nat. Genet.
, vol.9
, Issue.4
, pp. 439-443
-
-
Merajver, S.D.1
Pham, T.M.2
Caduff, R.F.3
Chen, M.4
Poy, E.L.5
Cooney, K.A.6
-
6
-
-
0035479017
-
BRCA1-associated tumorigenesis: What have we learned from knockout mice?
-
S.G. Brodie, and C.X. Deng BRCA1-associated tumorigenesis: what have we learned from knockout mice? Trends Genet. 17 10 2001 S18 S22
-
(2001)
Trends Genet.
, vol.17
, Issue.10
-
-
Brodie, S.G.1
Deng, C.X.2
-
7
-
-
13944281226
-
Molecular functions of BRCA1 in the DNA damage response
-
R. Scully, A. Xie, and G. Nagaraju Molecular functions of BRCA1 in the DNA damage response Cancer Biol. Ther. 3 6 2004 521 527
-
(2004)
Cancer Biol. Ther.
, vol.3
, Issue.6
, pp. 521-527
-
-
Scully, R.1
Xie, A.2
Nagaraju, G.3
-
8
-
-
4544374528
-
BRCA1 and BRCA2: 1994 and beyond
-
S.A. Narod, and W.D. Foulkes BRCA1 and BRCA2: 1994 and beyond Nat. Rev. Cancer 4 9 2004 665 676
-
(2004)
Nat. Rev. Cancer
, vol.4
, Issue.9
, pp. 665-676
-
-
Narod, S.A.1
Foulkes, W.D.2
-
9
-
-
0030850047
-
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
-
R. Scully, J. Chen, R.L. Ochs, K. Keegan, M. Hoekstra, J. Feunteun, and D.M. Livingston Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage Cell 90 3 1997 425 435
-
(1997)
Cell
, vol.90
, Issue.3
, pp. 425-435
-
-
Scully, R.1
Chen, J.2
Ochs, R.L.3
Keegan, K.4
Hoekstra, M.5
Feunteun, J.6
Livingston, D.M.7
-
10
-
-
0030570004
-
Location of BRCA1 in human breast and ovarian cancer cells [letter; Comment]
-
R. Scully, S. Ganesan, M. Brown, J.A. de Caprio, S.A. Cannistra, and J. Feunteun Location of BRCA1 in human breast and ovarian cancer cells [letter; comment] Science 272 5258 1996 123 126
-
(1996)
Science
, vol.272
, Issue.5258
, pp. 123-126
-
-
Scully, R.1
Ganesan, S.2
Brown, M.3
De Caprio, J.A.4
Cannistra, S.A.5
Feunteun, J.6
-
11
-
-
0033213392
-
Brca1 controls homology-directed DNA repair
-
M.E. Moynahan, J.W. Chiu, B.H. Koller, and M. Jasin Brca1 controls homology-directed DNA repair Mol. Cell 4 4 1999 511 518
-
(1999)
Mol. Cell
, vol.4
, Issue.4
, pp. 511-518
-
-
Moynahan, M.E.1
Chiu, J.W.2
Koller, B.H.3
Jasin, M.4
-
12
-
-
85047697866
-
A single mutated BRCA1 allele leads to impaired fidelity of double strand break end-joining
-
C. Baldeyron, E. Jacquemin, J. Smith, C. Jacquemont, I. De Oliveira, and S. Gad A single mutated BRCA1 allele leads to impaired fidelity of double strand break end-joining Oncogene 21 9 2002 1401 1410
-
(2002)
Oncogene
, vol.21
, Issue.9
, pp. 1401-1410
-
-
Baldeyron, C.1
Jacquemin, E.2
Smith, J.3
Jacquemont, C.4
De Oliveira, I.5
Gad, S.6
-
13
-
-
0035136283
-
Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2
-
H. Wang, Z.C. Zeng, T.A. Bui, S.J. DiBiase, W. Qin, and F. Xia Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2 Cancer Res. 61 1 2001 270 277
-
(2001)
Cancer Res.
, vol.61
, Issue.1
, pp. 270-277
-
-
Wang, H.1
Zeng, Z.C.2
Bui, T.A.3
Dibiase, S.J.4
Qin, W.5
Xia, F.6
-
14
-
-
0037099520
-
Deficient nonhomologous end-joining activity in cell-free extracts from Brca1-null fibroblasts
-
Q. Zhong, T.G. Boyer, P.L. Chen, and W.H. Lee Deficient nonhomologous end-joining activity in cell-free extracts from Brca1-null fibroblasts Cancer Res. 62 14 2002 3966 3970
-
(2002)
Cancer Res.
, vol.62
, Issue.14
, pp. 3966-3970
-
-
Zhong, Q.1
Boyer, T.G.2
Chen, P.L.3
Lee, W.H.4
-
15
-
-
0033603440
-
BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair
-
D.W. Abbott, M.E. Thompson, C. Robinson-Benion, G. Tomlinson, R.A. Jensen, and J.T. Holt BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair J. Biol. Chem. 274 26 1999 18808 18812
-
(1999)
J. Biol. Chem.
, vol.274
, Issue.26
, pp. 18808-18812
-
-
Abbott, D.W.1
Thompson, M.E.2
Robinson-Benion, C.3
Tomlinson, G.4
Jensen, R.A.5
Holt, J.T.6
-
16
-
-
0037047387
-
BRCA1 facilitates microhomology-mediated end joining of DNA double strand breaks
-
Q. Zhong, C.F. Chen, P.L. Chen, and W.H. Lee BRCA1 facilitates microhomology-mediated end joining of DNA double strand breaks J. Biol. Chem. 277 32 2002 28641 28647
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.32
, pp. 28641-28647
-
-
Zhong, Q.1
Chen, C.F.2
Chen, P.L.3
Lee, W.H.4
-
17
-
-
0032542216
-
A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability
-
S.X. Shen, Z. Weaver, X. Xu, C. Li, M. Weinstein, and L. Chen A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability Oncogene 17 24 1998 3115 3124
-
(1998)
Oncogene
, vol.17
, Issue.24
, pp. 3115-3124
-
-
Shen, S.X.1
Weaver, Z.2
Xu, X.3
Li, C.4
Weinstein, M.5
Chen, L.6
-
18
-
-
0034707047
-
The DNA damage response: Putting checkpoints in perspective
-
B.B. Zhou, and S.J. Elledge The DNA damage response: putting checkpoints in perspective Nature 408 6811 2000 433 439
-
(2000)
Nature
, vol.408
, Issue.6811
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
-
19
-
-
0035805582
-
The ring heterodimer brca1-bard1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation
-
R. Hashizume, M. Fukuda, I. Maeda, H. Nishikawa, D. Oyake, and Y. Yabuki The ring heterodimer brca1-bard1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation J. Biol. Chem. 276 18 2001 14537 14540
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.18
, pp. 14537-14540
-
-
Hashizume, R.1
Fukuda, M.2
Maeda, I.3
Nishikawa, H.4
Oyake, D.5
Yabuki, Y.6
-
20
-
-
0035942190
-
Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity
-
H. Ruffner, C.A. Joazeiro, D. Hemmati, T. Hunter, and I.M. Verma Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity Proc. Natl Acad. Sci. USA 98 9 2001 5134 5139
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, Issue.9
, pp. 5134-5139
-
-
Ruffner, H.1
Joazeiro, C.A.2
Hemmati, D.3
Hunter, T.4
Verma, I.M.5
-
21
-
-
0034697973
-
BRCA1 is associated with a human SWI/SNF-related complex: Linking chromatin remodeling to breast cancer
-
D.A. Bochar, L. Wang, H. Beniya, A. Kinev, Y. Xue, and W.S. Lane BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer Cell 102 2 2000 257 265
-
(2000)
Cell
, vol.102
, Issue.2
, pp. 257-265
-
-
Bochar, D.A.1
Wang, L.2
Beniya, H.3
Kinev, A.4
Xue, Y.5
Lane, W.S.6
-
22
-
-
0033609057
-
BRCA1 interacts with components of the histone deacetylase complex
-
R.I. Yarden, and L.C. Brody BRCA1 interacts with components of the histone deacetylase complex Proc. Natl Acad. Sci. USA 96 9 1999 4983 4988
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, Issue.9
, pp. 4983-4988
-
-
Yarden, R.I.1
Brody, L.C.2
-
23
-
-
20644461718
-
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function
-
S.B. Cantor, D.W. Bell, S. Ganesan, E.M. Kass, R. Drapkin, and S. Grossman BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function Cell 105 1 2001 149 160
-
(2001)
Cell
, vol.105
, Issue.1
, pp. 149-160
-
-
Cantor, S.B.1
Bell, D.W.2
Ganesan, S.3
Kass, E.M.4
Drapkin, R.5
Grossman, S.6
-
24
-
-
0032532543
-
BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells
-
Q. Wang, H. Zhang, K. Kajino, and M.I. Greene BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells Oncogene 17 15 1998 1939 1948
-
(1998)
Oncogene
, vol.17
, Issue.15
, pp. 1939-1948
-
-
Wang, Q.1
Zhang, H.2
Kajino, K.3
Greene, M.I.4
-
25
-
-
0030474170
-
Evidence for a transcriptional activation function of BRCA1 C-terminal region
-
A.N. Monteiro, A. August, and H. Hanafusa Evidence for a transcriptional activation function of BRCA1 C-terminal region Proc. Natl Acad. Sci. USA 93 24 1996 13595 13599
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, Issue.24
, pp. 13595-13599
-
-
Monteiro, A.N.1
August, A.2
Hanafusa, H.3
-
26
-
-
0029830051
-
Transcriptional activation by BRCA1 [letter; Comment]
-
M.S. Chapman, and I.M. Verma Transcriptional activation by BRCA1 [letter; comment] Nature 382 6593 1996 678 679
-
(1996)
Nature
, vol.382
, Issue.6593
, pp. 678-679
-
-
Chapman, M.S.1
Verma, I.M.2
-
27
-
-
0001221269
-
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
-
F.E. Kleiman, and J.L. Manley Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50 Science 285 5433 1999 1576 1579
-
(1999)
Science
, vol.285
, Issue.5433
, pp. 1576-1579
-
-
Kleiman, F.E.1
Manley, J.L.2
-
28
-
-
0346732323
-
BRCA1 associates with processive RNA polymerase II
-
S.A. Krum, G.A. Miranda, C. Lin, and T.F. Lane BRCA1 associates with processive RNA polymerase II J. Biol. Chem. 278 52 2003 52012 52020
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.52
, pp. 52012-52020
-
-
Krum, S.A.1
Miranda, G.A.2
Lin, C.3
Lane, T.F.4
-
29
-
-
0030965157
-
BRCA1 is a component of the RNA polymerase II holoenzyme
-
R. Scully, S.F. Anderson, D.M. Chao, W. Wei, L. Ye, and R.A. Young BRCA1 is a component of the RNA polymerase II holoenzyme Proc. Natl Acad. Sci. USA 94 11 1997 5605 5610
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, Issue.11
, pp. 5605-5610
-
-
Scully, R.1
Anderson, S.F.2
Chao, D.M.3
Wei, W.4
Ye, L.5
Young, R.A.6
-
30
-
-
0034306456
-
BRCA1: Exploring the links to transcription
-
A.N. Monteiro BRCA1: exploring the links to transcription Trends Biochem. Sci. 25 10 2000 469 474
-
(2000)
Trends Biochem. Sci.
, vol.25
, Issue.10
, pp. 469-474
-
-
Monteiro, A.N.1
-
31
-
-
0037684805
-
The multiple nuclear functions of BRCA1: Transcription, ubiquitination and DNA repair
-
L.M. Starita, and J.D. Parvin The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair Curr. Opin. Cell Biol. 15 3 2003 345 350
-
(2003)
Curr. Opin. Cell Biol.
, vol.15
, Issue.3
, pp. 345-350
-
-
Starita, L.M.1
Parvin, J.D.2
-
32
-
-
0033605264
-
Mapping the functional domains of BRCA1. Interaction of the ring finger domains of BRCA1 and BARD1
-
J.E. Meza, P.S. Brzovic, M.C. King, and R.E. Klevit Mapping the functional domains of BRCA1. Interaction of the ring finger domains of BRCA1 and BARD1 J. Biol. Chem. 274 9 1999 5659 5665
-
(1999)
J. Biol. Chem.
, vol.274
, Issue.9
, pp. 5659-5665
-
-
Meza, J.E.1
Brzovic, P.S.2
King, M.C.3
Klevit, R.E.4
-
33
-
-
10544231876
-
Identification of a RING protein that can interact in vivo with the BRCA1 gene product
-
L.C. Wu, Z.W. Wang, J.T. Tsan, M.A. Spillman, A. Phung, and X.L. Xu Identification of a RING protein that can interact in vivo with the BRCA1 gene product Nat. Genet. 14 4 1996 430 440
-
(1996)
Nat. Genet.
, vol.14
, Issue.4
, pp. 430-440
-
-
Wu, L.C.1
Wang, Z.W.2
Tsan, J.T.3
Spillman, M.A.4
Phung, A.5
Xu, X.L.6
-
34
-
-
0034791090
-
Ubiquitin enters the new millennium
-
C.M. Pickart Ubiquitin enters the new millennium Mol. Cell 8 3 2001 499 504
-
(2001)
Mol. Cell
, vol.8
, Issue.3
, pp. 499-504
-
-
Pickart, C.M.1
-
35
-
-
0020804563
-
Ubiquitin: Roles in protein modification and breakdown
-
A. Hershko Ubiquitin: roles in protein modification and breakdown Cell 34 1 1983 11 12
-
(1983)
Cell
, vol.34
, Issue.1
, pp. 11-12
-
-
Hershko, A.1
-
36
-
-
0034915764
-
Mechanisms underlying ubiquitination
-
C.M. Pickart Mechanisms underlying ubiquitination Annu. Rev. Biochem. 70 2001 503 533
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 503-533
-
-
Pickart, C.M.1
-
37
-
-
0033613222
-
RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination
-
K.L. Lorick, J.P. Jensen, S. Fang, A.M. Ong, S. Hatakeyama, and A.M. Weissman RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination Proc. Natl Acad. Sci. USA 96 20 1999 11364 11369
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, Issue.20
, pp. 11364-11369
-
-
Lorick, K.L.1
Jensen, J.P.2
Fang, S.3
Ong, A.M.4
Hatakeyama, S.5
Weissman, A.M.6
-
38
-
-
0036467574
-
The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity
-
R. Baer, and T. Ludwig The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity Curr. Opin. Genet. Dev. 12 1 2002 86 91
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, Issue.1
, pp. 86-91
-
-
Baer, R.1
Ludwig, T.2
-
39
-
-
0042671242
-
BRCA1-independent ubiquitination of FANCD2
-
C.J. Vandenberg, F. Gergely, C.Y. Ong, P. Pace, D.L. Mallery, K. Hiom, and K.J. Patel BRCA1-independent ubiquitination of FANCD2 Mol. Cell 12 1 2003 247 254
-
(2003)
Mol. Cell
, vol.12
, Issue.1
, pp. 247-254
-
-
Vandenberg, C.J.1
Gergely, F.2
Ong, C.Y.3
Pace, P.4
Mallery, D.L.5
Hiom, K.6
Patel, K.J.7
-
40
-
-
0037122004
-
Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains
-
D.L. Mallery, C.J. Vandenberg, and K. Hiom Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains Eur. Mol. Biol. Organ. J. 21 24 2002 6755 6762
-
(2002)
Eur. Mol. Biol. Organ. J.
, vol.21
, Issue.24
, pp. 6755-6762
-
-
Mallery, D.L.1
Vandenberg, C.J.2
Hiom, K.3
-
41
-
-
0037076672
-
Autoubiquitination of the BRCA1*BARD1 RING ubiquitin ligase
-
A. Chen, F.E. Kleiman, J.L. Manley, T. Ouchi, and Z.Q. Pan Autoubiquitination of the BRCA1*BARD1 RING ubiquitin ligase J. Biol. Chem. 277 24 2002 22085 22092
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.24
, pp. 22085-22092
-
-
Chen, A.1
Kleiman, F.E.2
Manley, J.L.3
Ouchi, T.4
Pan, Z.Q.5
-
42
-
-
3843059160
-
Nucleophosmin/B23 is a candidate substrate for the BRCA1-BARD1 ubiquitin ligase
-
K. Sato, R. Hayami, W. Wu, T. Nishikawa, H. Nishikawa, and Y. Okuda Nucleophosmin/B23 is a candidate substrate for the BRCA1-BARD1 ubiquitin ligase J. Biol. Chem. 279 30 2004 30919 30922
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.30
, pp. 30919-30922
-
-
Sato, K.1
Hayami, R.2
Wu, W.3
Nishikawa, T.4
Nishikawa, H.5
Okuda, Y.6
-
43
-
-
4544240599
-
BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number
-
L.M. Starita, Y. Machida, S. Sankaran, J.E. Elias, K. Griffin, and B.P. Schlegel BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number Mol. Cell Biol. 24 19 2004 8457 8466
-
(2004)
Mol. Cell Biol.
, vol.24
, Issue.19
, pp. 8457-8466
-
-
Starita, L.M.1
MacHida, Y.2
Sankaran, S.3
Elias, J.E.4
Griffin, K.5
Schlegel, B.P.6
-
44
-
-
0345276495
-
Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair
-
Y. Dong, M.A. Hakimi, X. Chen, E. Kumaraswamy, N.S. Cooch, A.K. Godwin, and R. Shiekhattar Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair Mol. Cell 12 5 2003 1087 1099
-
(2003)
Mol. Cell
, vol.12
, Issue.5
, pp. 1087-1099
-
-
Dong, Y.1
Hakimi, M.A.2
Chen, X.3
Kumaraswamy, E.4
Cooch, N.S.5
Godwin, A.K.6
Shiekhattar, R.7
-
45
-
-
4043130959
-
Ubiquitination and proteasomal degradation of the BRCA1 tumor suppressor is regulated during cell cycle progression
-
A.D. Choudhury, H. Xu, and R. Baer Ubiquitination and proteasomal degradation of the BRCA1 tumor suppressor is regulated during cell cycle progression J. Biol. Chem. 279 32 2004 33909 33918
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.32
, pp. 33909-33918
-
-
Choudhury, A.D.1
Xu, H.2
Baer, R.3
-
46
-
-
0034737439
-
Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139
-
E.P. Rogakou, W. Nieves-Neira, C. Boon, Y. Pommier, and W.M. Bonner Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139 J. Biol. Chem. 275 13 2000 9390 9395
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.13
, pp. 9390-9395
-
-
Rogakou, E.P.1
Nieves-Neira, W.2
Boon, C.3
Pommier, Y.4
Bonner, W.M.5
-
47
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
T.T. Paull, E.P. Rogakou, V. Yamazaki, C.U. Kirchgessner, M. Gellert, and W.M. Bonner A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage Curr. Biol. 10 15 2000 886 895
-
(2000)
Curr. Biol.
, vol.10
, Issue.15
, pp. 886-895
-
-
Paull, T.T.1
Rogakou, E.P.2
Yamazaki, V.3
Kirchgessner, C.U.4
Gellert, M.5
Bonner, W.M.6
-
48
-
-
0042317328
-
The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin
-
F. Wu-Baer, K. Lagrazon, W. Yuan, and R. Baer The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin J. Biol. Chem. 278 37 2003 34743 34746
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.37
, pp. 34743-34746
-
-
Wu-Baer, F.1
Lagrazon, K.2
Yuan, W.3
Baer, R.4
-
49
-
-
1042278177
-
Mass spectrometric and mutational analyses reveal Lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligase
-
H. Nishikawa, S. Ooka, K. Sato, K. Arima, J. Okamoto, and R.E. Klevit Mass spectrometric and mutational analyses reveal Lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligase J. Biol. Chem. 279 6 2004 3916 3924
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.6
, pp. 3916-3924
-
-
Nishikawa, H.1
Ooka, S.2
Sato, K.3
Arima, K.4
Okamoto, J.5
Klevit, R.E.6
-
50
-
-
0030187780
-
BRCA1 protein products... Functional motifs... [letter]
-
E.V. Koonin, S.F. Altschul, and P. Bork BRCA1 protein products... Functional motifs... [letter] Nat. Genet. 13 3 1996 266 268
-
(1996)
Nat. Genet.
, vol.13
, Issue.3
, pp. 266-268
-
-
Koonin, E.V.1
Altschul, S.F.2
Bork, P.3
-
51
-
-
0031046294
-
A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins
-
P. Bork, K. Hofmann, P. Bucher, A.F. Neuwald, S.F. Altschul, and E.V. Koonin A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins Fed. Am. Soc. Exp. Biol. J. 11 1 1997 68 76
-
(1997)
Fed. Am. Soc. Exp. Biol. J.
, vol.11
, Issue.1
, pp. 68-76
-
-
Bork, P.1
Hofmann, K.2
Bucher, P.3
Neuwald, A.F.4
Altschul, S.F.5
Koonin, E.V.6
-
52
-
-
0031031787
-
From BRCA1 to RAP1: A widespread BRCT module closely associated with DNA repair
-
I. Callebaut, and J.P. Mornon From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair Fed. Eur. Biochem. Soc. Lett. 400 1 1997 25 30
-
(1997)
Fed. Eur. Biochem. Soc. Lett.
, vol.400
, Issue.1
, pp. 25-30
-
-
Callebaut, I.1
Mornon, J.P.2
-
54
-
-
0346101743
-
Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains
-
M. Rodriguez, X. Yu, J. Chen, and Z. Songyang Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains J. Biol. Chem. 278 52 2003 52914 52918
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.52
, pp. 52914-52918
-
-
Rodriguez, M.1
Yu, X.2
Chen, J.3
Songyang, Z.4
-
55
-
-
0142240342
-
BRCT repeats as phosphopeptide-binding modules involved in protein targeting
-
I.A. Manke, D.M. Lowery, A. Nguyen, and M.B. Yaffe BRCT repeats as phosphopeptide-binding modules involved in protein targeting Science 302 5645 2003 636 639
-
(2003)
Science
, vol.302
, Issue.5645
, pp. 636-639
-
-
Manke, I.A.1
Lowery, D.M.2
Nguyen, A.3
Yaffe, M.B.4
-
56
-
-
0142147272
-
The BRCT domain is a phospho-protein binding domain
-
X. Yu, C.C. Chini, M. He, G. Mer, and J. Chen The BRCT domain is a phospho-protein binding domain Science 302 5645 2003 639 642
-
(2003)
Science
, vol.302
, Issue.5645
, pp. 639-642
-
-
Yu, X.1
Chini, C.C.2
He, M.3
Mer, G.4
Chen, J.5
-
58
-
-
2542489188
-
Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer
-
J.A. Clapperton, I.A. Manke, D.M. Lowery, T. Ho, L.F. Haire, M.B. Yaffe, and S.J. Smerdon Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer Nat. Struct. Mol. Biol. 2004
-
(2004)
Nat. Struct. Mol. Biol.
-
-
Clapperton, J.A.1
Manke, I.A.2
Lowery, D.M.3
Ho, T.4
Haire, L.F.5
Yaffe, M.B.6
Smerdon, S.J.7
-
59
-
-
3142608985
-
Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains
-
(Cambridge)
-
M.V. Botuyan, Y. Nomine, X. Yu, N. Juranic, S. Macura, J. Chen, and G. Mer Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains Structure (Cambridge) 12 7 2004 1137 1146
-
(2004)
Structure
, vol.12
, Issue.7
, pp. 1137-1146
-
-
Botuyan, M.V.1
Nomine, Y.2
Yu, X.3
Juranic, N.4
MacUra, S.5
Chen, J.6
Mer, G.7
-
60
-
-
2342484423
-
Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: Implications for signaling
-
E.N. Shiozaki, L. Gu, N. Yan, and Y. Shi Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling Mol. Cell 14 3 2004 405 412
-
(2004)
Mol. Cell
, vol.14
, Issue.3
, pp. 405-412
-
-
Shiozaki, E.N.1
Gu, L.2
Yan, N.3
Shi, Y.4
-
61
-
-
3543034594
-
BRCA1 can modulate RNA polymerase II carboxy-terminal domain phosphorylation levels
-
A. Moisan, C. Larochelle, B. Guillemette, and L. Gaudreau BRCA1 can modulate RNA polymerase II carboxy-terminal domain phosphorylation levels Mol. Cell Biol 24 16 2004 6947 6956
-
(2004)
Mol. Cell Biol.
, vol.24
, Issue.16
, pp. 6947-6956
-
-
Moisan, A.1
Larochelle, C.2
Guillemette, B.3
Gaudreau, L.4
-
62
-
-
0033400828
-
Genetic analysis of BRCA1 function in a defined tumor cell line
-
R. Scully, S. Ganesan, K. Vlasakova, J. Chen, M. Socolovsky, and D.M. Livingston Genetic analysis of BRCA1 function in a defined tumor cell line Mol. Cell 4 6 1999 1093 1099
-
(1999)
Mol. Cell
, vol.4
, Issue.6
, pp. 1093-1099
-
-
Scully, R.1
Ganesan, S.2
Vlasakova, K.3
Chen, J.4
Socolovsky, M.5
Livingston, D.M.6
-
63
-
-
1842364973
-
Localization of BRCA1 and a splice variant identifies the nuclear localization signal
-
S. Thakur, H.B. Zhang, Y. Peng, H. Le, B. Carroll, and T. Ward Localization of BRCA1 and a splice variant identifies the nuclear localization signal Mol. Cell Biol. 17 1 1997 444 452
-
(1997)
Mol. Cell Biol.
, vol.17
, Issue.1
, pp. 444-452
-
-
Thakur, S.1
Zhang, H.B.2
Peng, Y.3
Le, H.4
Carroll, B.5
Ward, T.6
-
64
-
-
0034623941
-
Identification of a functional nuclear export sequence in BRCA1
-
J.A. Rodriguez, and B.R. Henderson Identification of a functional nuclear export sequence in BRCA1 J. Biol. Chem. 275 49 2000 38589 38596
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.49
, pp. 38589-38596
-
-
Rodriguez, J.A.1
Henderson, B.R.2
-
65
-
-
0347320584
-
Cytoplasmic mislocalization of BRCA1 caused by cancer-associated mutations in the BRCT domain
-
J.A. Rodriguez, W.W. Au, and B.R. Henderson Cytoplasmic mislocalization of BRCA1 caused by cancer-associated mutations in the BRCT domain Exp. Cell Res. 293 1 2004 14 21
-
(2004)
Exp. Cell Res.
, vol.293
, Issue.1
, pp. 14-21
-
-
Rodriguez, J.A.1
Au, W.W.2
Henderson, B.R.3
-
66
-
-
0037130887
-
Cancer incidence in BRCA1 mutation carriers
-
D. Thompson, and D.F. Easton Cancer incidence in BRCA1 mutation carriers J. Natl Cancer Inst. 94 18 2002 1358 1365
-
(2002)
J. Natl Cancer Inst.
, vol.94
, Issue.18
, pp. 1358-1365
-
-
Thompson, D.1
Easton, D.F.2
-
67
-
-
0038204416
-
BRCA1: The enigma of tissue-specific tumor development
-
A.N. Monteiro BRCA1: the enigma of tissue-specific tumor development Trends Genet. 19 6 2003 312 315
-
(2003)
Trends Genet.
, vol.19
, Issue.6
, pp. 312-315
-
-
Monteiro, A.N.1
-
68
-
-
0035804228
-
Role of direct interaction in BRCA1 inhibition of estrogen receptor activity
-
S. Fan, Y.X. Ma, C. Wang, R.Q. Yuan, Q. Meng, and J.A. Wang Role of direct interaction in BRCA1 inhibition of estrogen receptor activity Oncogene 20 1 2001 77 87
-
(2001)
Oncogene
, vol.20
, Issue.1
, pp. 77-87
-
-
Fan, S.1
Ma, Y.X.2
Wang, C.3
Yuan, R.Q.4
Meng, Q.5
Wang, J.A.6
-
69
-
-
0035859823
-
BRCA1 mediates ligand-independent transcriptional repression of the estrogen receptor
-
L. Zheng, L.A. Annab, C.A. Afshari, W.H. Lee, and T.G. Boyer BRCA1 mediates ligand-independent transcriptional repression of the estrogen receptor Proc. Natl Acad. Sci. USA 98 17 2001 9587 9592
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, Issue.17
, pp. 9587-9592
-
-
Zheng, L.1
Annab, L.A.2
Afshari, C.A.3
Lee, W.H.4
Boyer, T.G.5
-
70
-
-
0036491931
-
The BRCA1 suppressor hypothesis: An explanation for the tissue-specific tumor development in BRCA1 patients
-
S.J. Elledge, and A. Amon The BRCA1 suppressor hypothesis: an explanation for the tissue-specific tumor development in BRCA1 patients Cancer Cell 1 2002 129 132
-
(2002)
Cancer Cell
, vol.1
, pp. 129-132
-
-
Elledge, S.J.1
Amon, A.2
|