메뉴 건너뛰기




Volumn 79, Issue 15, 2005, Pages 9821-9830

Human immunodeficiency virus reactivation by phorbol esters or T-cell receptor ligation requires both PKCα and PKCθ

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN; ISOPROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL ESTER DERIVATIVE; PROSTATIN; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C ALPHA AGONIST; PROTEIN KINASE C THETA; PROTEIN KINASE C THETA AGONIST; RNA; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

EID: 22544466722     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.15.9821-9830.2005     Document Type: Article
Times cited : (49)

References (61)
  • 1
    • 0028301838 scopus 로고
    • Cellular latency in human immunodeficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter-proximal transcripts
    • Adams, M., L. Sharmeen, J. Kimpton, J. M. Romeo, J. V. Garcia, B. M. Peterlin, M. Groudine, and M. Emerman. 1994. Cellular latency in human immunodeficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter-proximal transcripts. Proc. Natl. Acad. Sci. USA 91:3862-3866.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3862-3866
    • Adams, M.1    Sharmeen, L.2    Kimpton, J.3    Romeo, J.M.4    Garcia, J.V.5    Peterlin, B.M.6    Groudine, M.7    Emerman, M.8
  • 3
    • 0027418818 scopus 로고
    • Molecular cloning and characterization of PKC-theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells
    • Baier, G., D. Telford, L. Giampa, K. M. Coggeshall, G. Baier-Bitterlich, N. Isakov, and A. Altman. 1993. Molecular cloning and characterization of PKC-theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells. J. Biol. Chem. 268:4997-5004.
    • (1993) J. Biol. Chem. , vol.268 , pp. 4997-5004
    • Baier, G.1    Telford, D.2    Giampa, L.3    Coggeshall, K.M.4    Baier-Bitterlich, G.5    Isakov, N.6    Altman, A.7
  • 5
    • 0031813707 scopus 로고    scopus 로고
    • Specific killing of HIV-infected lymphocytes by a recombinant immunotoxin directed against the HIV-1 envelope glycoprotein
    • Bera, T. K., P. E. Kennedy, E. A. Berger, C. F. I. Barbas, and I. Pastan. 1998. Specific killing of HIV-infected lymphocytes by a recombinant immunotoxin directed against the HIV-1 envelope glycoprotein. Mol. Med. 4:384-391.
    • (1998) Mol. Med. , vol.4 , pp. 384-391
    • Bera, T.K.1    Kennedy, P.E.2    Berger, E.A.3    Barbas, C.F.I.4    Pastan, I.5
  • 7
    • 4544360251 scopus 로고    scopus 로고
    • Dual role of prostratin in inhibition of infection and reactivation of human immunodeficiency virus from latency in primary blood lymphocytes and lymphoid tissue
    • Biancotto, A., J.-C. Grivel, F. Gondois-Rey, L. Bettendroffer, R. Vigne, S. Brown, L. B. Margolis, and I. Hirsch. 2004. Dual role of prostratin in inhibition of infection and reactivation of human immunodeficiency virus from latency in primary blood lymphocytes and lymphoid tissue. J. Virol. 78:10507-10515.
    • (2004) J. Virol. , vol.78 , pp. 10507-10515
    • Biancotto, A.1    Grivel, J.-C.2    Gondois-Rey, F.3    Bettendroffer, L.4    Vigne, R.5    Brown, S.6    Margolis, L.B.7    Hirsch, I.8
  • 8
    • 0041743235 scopus 로고    scopus 로고
    • Activation of latent HIV-1 expression by the potent anti-tumor promoter 12-deoxyphorbol 13-phenylacetate
    • Bocklandt, S., P. M. Blumberg, and D. H. Hamer. 2003. Activation of latent HIV-1 expression by the potent anti-tumor promoter 12-deoxyphorbol 13-phenylacetate. Antivir. Res. 59:89-98.
    • (2003) Antivir. Res. , vol.59 , pp. 89-98
    • Bocklandt, S.1    Blumberg, P.M.2    Hamer, D.H.3
  • 9
    • 0242268402 scopus 로고    scopus 로고
    • Identification of T cell-signaling pathways that stimulate latent HIV in primary cells
    • Brooks, D. G., P. A. Arlen, L. Gao, C. M. Kitchen, and J. A. Zack. 2003. Identification of T cell-signaling pathways that stimulate latent HIV in primary cells. Proc. Natl. Acad. Sci. USA 100:12955-12960.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 12955-12960
    • Brooks, D.G.1    Arlen, P.A.2    Gao, L.3    Kitchen, C.M.4    Zack, J.A.5
  • 14
    • 0028792184 scopus 로고
    • In vivo fate of HIV-1-infected T cells: Quantitative analysis of the transition to stable latency
    • Chun, T.-W., D. Finzi, J. Margolick, K. Chadwick, D. Schwartz, and R. F. Siliciano. 1995. In vivo fate of HIV-1-infected T cells: quantitative analysis of the transition to stable latency. Nat. Med. 1:1284-1290.
    • (1995) Nat. Med. , vol.1 , pp. 1284-1290
    • Chun, T.-W.1    Finzi, D.2    Margolick, J.3    Chadwick, K.4    Schwartz, D.5    Siliciano, R.F.6
  • 16
    • 0034724201 scopus 로고    scopus 로고
    • NF-κB activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta
    • Coudronniere, N., M. Villalba, N. Englund, and A. Altman. 2000, NF-κB activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta. Proc. Natl. Acad. Sci. USA 97:3394-3399.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 3394-3399
    • Coudronniere, N.1    Villalba, M.2    Englund, N.3    Altman, A.4
  • 17
    • 0001488150 scopus 로고
    • Tumor necrosis factor alpha activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-κB sites in the long terminal repeat
    • Duh, E. J., W. J. Maury, T. M. Folks, A. S. Fauci, and A. B. Rabson. 1989. Tumor necrosis factor alpha activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-κB sites in the long terminal repeat. Proc. Natl. Acad. Sci. USA 86:5974-5978,
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 5974-5978
    • Duh, E.J.1    Maury, W.J.2    Folks, T.M.3    Fauci, A.S.4    Rabson, A.B.5
  • 20
    • 0010472999 scopus 로고
    • Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone
    • Folks, T. M., K. A. Clouse, J. Justement, A. Rabson, E. Duh, J. H. Kehrl, and A. S. Fauci. 1989. Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone. Proc. Natl. Acad. Sci. USA 86:2365-2368.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 2365-2368
    • Folks, T.M.1    Clouse, K.A.2    Justement, J.3    Rabson, A.4    Duh, E.5    Kehrl, J.H.6    Fauci, A.S.7
  • 21
    • 0034081778 scopus 로고    scopus 로고
    • Chimeric toxins targeted to the human immunodeficiency virus type 1 envelope glycoprotein augment the in vivo activity of combination antiretroviral therapy in thy/liv-SCID-Hu mice
    • Goldstein, H., M. Pettoello-Mantovani, T. K. Bera, I. H. Pastan, and E. A. Berger. 2000. Chimeric toxins targeted to the human immunodeficiency virus type 1 envelope glycoprotein augment the in vivo activity of combination antiretroviral therapy in thy/liv-SCID-Hu mice. J. Infect. Dis. 181:921-926,
    • (2000) J. Infect. Dis. , vol.181 , pp. 921-926
    • Goldstein, H.1    Pettoello-Mantovani, M.2    Bera, T.K.3    Pastan, I.H.4    Berger, E.A.5
  • 22
    • 0031023704 scopus 로고    scopus 로고
    • Antireplicative and anticytopathic activities of prostratin, a non-tumor-promoting phorbol ester, against human immunodeficiency virus (HIV)
    • Gulakowski, R. J., J. B. McMahon, R. W. Buckheit, Jr., K. R. Gustafson, and M. R. Boyd. 1997. Antireplicative and anticytopathic activities of prostratin, a non-tumor-promoting phorbol ester, against human immunodeficiency virus (HIV). Antivir. Res. 33:87-97.
    • (1997) Antivir. Res. , vol.33 , pp. 87-97
    • Gulakowski, R.J.1    McMahon, J.B.2    Buckheit Jr., R.W.3    Gustafson, K.R.4    Boyd, M.R.5
  • 25
    • 0026752139 scopus 로고
    • Human immunodeficiency virus type 1 Tat-mediated trans activation correlates with the phosphorylation state of a cellular TAR RNA stem-binding factor
    • Han, X. M., A. Laras, M. P. Rounseville, A. Kumar, and P. R. Shank. 1992. Human immunodeficiency virus type 1 Tat-mediated trans activation correlates with the phosphorylation state of a cellular TAR RNA stem-binding factor. J. Virol. 66:4065-4072.
    • (1992) J. Virol. , vol.66 , pp. 4065-4072
    • Han, X.M.1    Laras, A.2    Rounseville, M.P.3    Kumar, A.4    Shank, P.R.5
  • 27
    • 0025342317 scopus 로고
    • Trans-activation of HIV-1 LTR-directed gene expression by tat requires protein kinase C
    • Jakobovits, A., A. Rosenthal, and D. J. Capon. 1990. Trans-activation of HIV-1 LTR-directed gene expression by tat requires protein kinase C. EMBO J. 9:1165-1170.
    • (1990) EMBO J. , vol.9 , pp. 1165-1170
    • Jakobovits, A.1    Rosenthal, A.2    Capon, D.J.3
  • 28
    • 0028290825 scopus 로고
    • Control of RNA initiation and elongation at the HIV-1 promoter
    • Jones, K. A., and B. M. Peterlin. 1994. Control of RNA initiation and elongation at the HIV-1 promoter. Annu. Rev. Biochem. 63:717-743.
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 717-743
    • Jones, K.A.1    Peterlin, B.M.2
  • 29
    • 0025004457 scopus 로고
    • Direct and cytokine-mediated activation of protein kinase C induces human immunodeficiency virus expression in chronically infected promonocytic cells
    • Kinter, A. L., G. Poli, W. Maury, T. M. Folks, and A. S. Fauci. 1990. Direct and cytokine-mediated activation of protein kinase C induces human immunodeficiency virus expression in chronically infected promonocytic cells. J. Virol. 64:4306-4312.
    • (1990) J. Virol. , vol.64 , pp. 4306-4312
    • Kinter, A.L.1    Poli, G.2    Maury, W.3    Folks, T.M.4    Fauci, A.S.5
  • 30
    • 0036315848 scopus 로고    scopus 로고
    • Effects of prostratin on T-cell activation and human immunodeficiency virus latency
    • Korin, Y. D., D. G. Brooks, S. Brown, A. Korotzer, and J. A. Zack. 2002. Effects of prostratin on T-cell activation and human immunodeficiency virus latency. J. Virol. 76:8118-8123.
    • (2002) J. Virol. , vol.76 , pp. 8118-8123
    • Korin, Y.D.1    Brooks, D.G.2    Brown, S.3    Korotzer, A.4    Zack, J.A.5
  • 31
    • 0035892120 scopus 로고    scopus 로고
    • Prostratin: Activation of latent HIV-1 expression suggests a potential inductive adjuvant therapy for HAART
    • Kulkosky, J., D. M. Culnan, J. Roman, G. Dornadula, M. Schnell, M. R. Boyd, and R. J. Pomerantz. 2001. Prostratin: activation of latent HIV-1 expression suggests a potential inductive adjuvant therapy for HAART. Blood 98:3006-3015.
    • (2001) Blood , vol.98 , pp. 3006-3015
    • Kulkosky, J.1    Culnan, D.M.2    Roman, J.3    Dornadula, G.4    Schnell, M.5    Boyd, M.R.6    Pomerantz, R.J.7
  • 34
    • 1842524184 scopus 로고    scopus 로고
    • SPAK kinase is a substrate and target of PKC-theta in T-cell receptor-induced AP-1 activation pathway
    • Li, Y., J. Hu, R. Vita, B. Sun, H. Tabata, and A. Altman. 2004. SPAK kinase is a substrate and target of PKC-theta in T-cell receptor-induced AP-1 activation pathway. EMBO J. 23:1112-1122.
    • (2004) EMBO J. , vol.23 , pp. 1112-1122
    • Li, Y.1    Hu, J.2    Vita, R.3    Sun, B.4    Tabata, H.5    Altman, A.6
  • 35
    • 0027996152 scopus 로고
    • In vitro study of functional involvement of Sp1, NF-κB/Rel, and AP1 in phorbol 12-myristate 13-acetate-mediated HIV-1 long terminal repeat activation
    • Li, Y., G. Mak, and B. R. Franza, Jr. 1994. In vitro study of functional involvement of Sp1, NF-κB/Rel, and AP1 in phorbol 12-myristate 13-acetate-mediated HIV-1 long terminal repeat activation. J. Biol. Chem. 269:30616-30619.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30616-30619
    • Li, Y.1    Mak, G.2    Franza Jr., B.R.3
  • 36
    • 0034031401 scopus 로고    scopus 로고
    • Protein kinase C-theta participates in NF-κB activation induced by CD3-CD28 costimulation through selective activation of IκB kinase β
    • Lin, X., A. O'Mahony, Y. Mu, R. Geleziunas, and W. C. Greene. 2000. Protein kinase C-theta participates in NF-κB activation induced by CD3-CD28 costimulation through selective activation of IκB kinase β. Mol. Cell. Biol. 20:2933-2940.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 2933-2940
    • Lin, X.1    O'Mahony, A.2    Mu, Y.3    Geleziunas, R.4    Greene, W.C.5
  • 37
    • 0027948936 scopus 로고
    • Hydroxyurea as an inhibitor of human immunodeficiency virus-type 1 replication
    • Lori, F., A. Malykh, A. Cara, D. Sun, J. N. Weinstein, J. Lisziewicz, and R. C. Gallo. 1994. Hydroxyurea as an inhibitor of human immunodeficiency virus-type 1 replication. Science 266:801-805.
    • (1994) Science , vol.266 , pp. 801-805
    • Lori, F.1    Malykh, A.2    Cara, A.3    Sun, D.4    Weinstein, J.N.5    Lisziewicz, J.6    Gallo, R.C.7
  • 38
    • 0037072948 scopus 로고    scopus 로고
    • Increased affinity and stability of an anti-HIV-1 envelope immunotoxin by structure-based mutagenesis
    • McHugh, L., S. Hu, B. K. Lee, K. Santora, P. E. Kennedy, E. A. Berger, I. Pastan, and D. H. Hamer. 2002. Increased affinity and stability of an anti-HIV-1 envelope immunotoxin by structure-based mutagenesis. J. Biol. Chem. 277:34383-34890.
    • (2002) J. Biol. Chem. , vol.277 , pp. 34383-34890
    • McHugh, L.1    Hu, S.2    Lee, B.K.3    Santora, K.4    Kennedy, P.E.5    Berger, E.A.6    Pastan, I.7    Hamer, D.H.8
  • 39
    • 10044298444 scopus 로고    scopus 로고
    • The link between PKCα regulation and cellular transformation
    • Michie, A. M., and R. Nakagawa. 2005. The link between PKCα regulation and cellular transformation. Immunol. Lett. 96:155-162.
    • (2005) Immunol. Lett. , vol.96 , pp. 155-162
    • Michie, A.M.1    Nakagawa, R.2
  • 40
    • 0023176085 scopus 로고
    • An inducible transcription factor activates expression of human immunodeficiency virus in T cells
    • Nabel, G., and D. Baltimore. 1987. An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature 326:711-713.
    • (1987) Nature , vol.326 , pp. 711-713
    • Nabel, G.1    Baltimore, D.2
  • 41
    • 0342742310 scopus 로고
    • Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor κB
    • Osborn, L., S, Kunkel, and G. J. Nabel. 1989. Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor κB. Proc. Natl. Acad. Sci. USA 86:2336-2340.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 2336-2340
    • Osborn, L.1    Kunkel, S.2    Nabel, G.J.3
  • 45
    • 0027336298 scopus 로고
    • Go 6976, a selective inhibitor of protein kinase C, is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level- producing reservoir cells in vitro
    • Qatsha, K A., C. Rudolph, D. Marme, C. Schachtele, and W. S. May. 1993. Go 6976, a selective inhibitor of protein kinase C, is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level-producing reservoir cells in vitro. Proc. Natl. Acad. Sci. USA 90:4674-4678.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4674-4678
    • Qatsha, K.A.1    Rudolph, C.2    Marme, D.3    Schachtele, C.4    May, W.S.5
  • 46
    • 0029980243 scopus 로고    scopus 로고
    • Activating protein-1 cooperates with phorbol ester activation signals to increase HIV-1 expression
    • Roebuck, K. A., D. S. Gu, and M. F. Kagnoff. 1996. Activating protein-1 cooperates with phorbol ester activation signals to increase HIV-1 expression. AIDS 10:819-826.
    • (1996) AIDS , vol.10 , pp. 819-826
    • Roebuck, K.A.1    Gu, D.S.2    Kagnoff, M.F.3
  • 49
    • 0036893434 scopus 로고    scopus 로고
    • Interleukin-7 induced expression of latent human immunodeficiency virus type 1 with minimal effects on T-cell phenotype
    • Scripture-Adams, D. D., D. G. Brooks, Y. D. Korin, and J. A. Zack. 2002. Interleukin-7 induced expression of latent human immunodeficiency virus type 1 with minimal effects on T-cell phenotype. J. Virol. 76:13077-13082.
    • (2002) J. Virol. , vol.76 , pp. 13077-13082
    • Scripture-Adams, D.D.1    Brooks, D.G.2    Korin, Y.D.3    Zack, J.A.4
  • 52
    • 0346023949 scopus 로고    scopus 로고
    • Characterization of TCR-induced phosphorylation of PKCθ in primary murine lymphocytes
    • Thebault, S., and J. Ochoa-Garay. 2004. Characterization of TCR-induced phosphorylation of PKCθ in primary murine lymphocytes. Mol. Immunol. 40:931-942.
    • (2004) Mol. Immunol. , vol.40 , pp. 931-942
    • Thebault, S.1    Ochoa-Garay, J.2
  • 53
    • 0033551804 scopus 로고    scopus 로고
    • Protein kinase C and calcineurin synergize to activate IκB kinase and NF-κB in T lymphocytes
    • Trushin, S. A., K. N. Pennington, A. Algeciras-Schimnich, and C. V. Paya. 1999. Protein kinase C and calcineurin synergize to activate IκB kinase and NF-κB in T lymphocytes. J. Biol. Chem. 274:22923-22931.
    • (1999) J. Biol. Chem. , vol.274 , pp. 22923-22931
    • Trushin, S.A.1    Pennington, K.N.2    Algeciras-Schimnich, A.3    Paya, C.V.4
  • 54
    • 0141669117 scopus 로고    scopus 로고
    • Protein kinase C-α (PKC-α) acts upstream of PKC-theta to activate IκB kinase and NF-κB in T lymphocytes
    • Trushin, S. A., K. N. Pennington, E. M. Carmona, S. Asin, D. N. Savoy, D. D. Billadeau, and C. V. Paya. 2003. Protein kinase C-α (PKC-α) acts upstream of PKC-theta to activate IκB kinase and NF-κB in T lymphocytes. Mol. Cell. Biol. 23:7068-7081.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 7068-7081
    • Trushin, S.A.1    Pennington, K.N.2    Carmona, E.M.3    Asin, S.4    Savoy, D.N.5    Billadeau, D.D.6    Paya, C.V.7
  • 56
    • 0032101707 scopus 로고    scopus 로고
    • Calcineurin preferentially synergizes with PKC-theta to activate JNK and IL-2 promoter in T lymphocytes
    • Werlen, G., E. Jacinto, Y. Xia, and M. Karin. 1998. Calcineurin preferentially synergizes with PKC-theta to activate JNK and IL-2 promoter in T lymphocytes. EMBO J. 17:3101-3111.
    • (1998) EMBO J. , vol.17 , pp. 3101-3111
    • Werlen, G.1    Jacinto, E.2    Xia, Y.3    Karin, M.4
  • 59
    • 0037458718 scopus 로고    scopus 로고
    • Potent suppression of viral infectivity by the peptides that inhibit multimerization of human immunodeficiency virus type 1 (HIV-1) Vif proteins
    • Yang, B., L. Gao, L. Li, Z. Lu, X. Fan, C. A. Patel, R. J. Pomerantz, G. C. DuBois, and H. Zhang. 2003. Potent suppression of viral infectivity by the peptides that inhibit multimerization of human immunodeficiency virus type 1 (HIV-1) Vif proteins. J. Biol. Chem. 278:6596-6602.
    • (2003) J. Biol. Chem. , vol.278 , pp. 6596-6602
    • Yang, B.1    Gao, L.2    Li, L.3    Lu, Z.4    Fan, X.5    Patel, C.A.6    Pomerantz, R.J.7    Dubois, G.C.8    Zhang, H.9
  • 60
    • 0033600851 scopus 로고    scopus 로고
    • ERK MAP kinase links cytokine signals to activation of latent HIV-1 infection by stimulating a cooperative interaction of AP-1 and NF-κB
    • Yang, X., Y. Chen, and D. Gabuzda. 1999. ERK MAP kinase links cytokine signals to activation of latent HIV-1 infection by stimulating a cooperative interaction of AP-1 and NF-κB. J. Biol. Chem. 274:27981-27988.
    • (1999) J. Biol. Chem. , vol.274 , pp. 27981-27988
    • Yang, X.1    Chen, Y.2    Gabuzda, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.