SPAK kinase is a substrate and target of PKCθ in T-cell receptor-induced AP-1 activation pathway

EMBO Journal

Volumn 23, Issue 5, 2004, Pages 1112-1122

  Li, Yingqiu ^a   Hu, Junru ^a   Vita, Randi ^a,b   Sun, Binggang ^a   Tabata, Hiroki ^a   Altman, Amnon ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b Androclus Therapeutics   (United States)

Author keywords

AP 1; PKC ; Signaling; SPAK; T cell

Indexed keywords

CD28 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C ALPHA; PROTEIN KINASE C THETA; PROTEIN SPAK; RECOMBINANT ENZYME; RNA; SERINE; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ISOLATION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGENS, CD28; CELL LINE; ENZYME ACTIVATION; HUMANS; ISOENZYMES; MICE; MICE, KNOCKOUT; NF-KAPPA B; PROTEIN BINDING; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; TRANSCRIPTION FACTOR AP-1;

ANIMALIA;

EID: 1842524184     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600125     Document Type: Article

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