Modulation of epithelial neoplasia and lymphoid hyperplasia in PTEN +/- mice by the p85 regulatory subunits of phosphoinositide 3-kinase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 29, 2005, Pages 10238-10243

  Luo, Ji ^a   Sobkiw, Cassandra L ^a   Logsdon, Nicole M ^a   Watt, John M ^a   Signoretti, Sabina ^b   O'Connell, Fionnuala ^b,c   Shin, Eyoung ^b,c   Shim, Youngju ^b,c   Pao, Lily ^a   Neel, Benjamin G ^a   DePinho, Ronald A ^c   Loda, Massimo ^b,c   Cantley, Lewis C ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

AKT; Intestinal polyps; Prostate intraepithelial neoplasia

Indexed keywords

KI 67 ANTIGEN; MONOCLONAL ANTIBODY CD3; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE P85; PHOSPHATIDYLINOSITOL 3 KINASE P85ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE P85BETA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOINOSITIDE PHOSPHATASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CELL PROLIFERATION; ENZYME ACTIVATION; EPITHELIUM; EPITHELIUM NEOPLASM; GENE DELETION; GENE LOSS; HETEROZYGOSITY; IMMUNOHISTOCHEMISTRY; INTESTINE POLYP; LYMPHOID HYPERPLASIA; MOUSE; NEOPLASM; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; PROSTATE TUMOR; PROSTATIC INTRAEPITHELIAL NEOPLASIA; PTEN GENE; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TUMOR SUPPRESSOR GENE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BLOTTING, WESTERN; FORKHEAD TRANSCRIPTION FACTORS; GIANT LYMPH NODE HYPERPLASIA; HETEROZYGOTE; IMMUNOHISTOCHEMISTRY; INTESTINAL POLYPS; KI-67 ANTIGEN; MALE; MICE; NEOPLASMS, GLANDULAR AND EPITHELIAL; PROSTATIC NEOPLASMS; PROTEIN-TYROSINE-PHOSPHATASE; PTEN PHOSPHOHYDROLASE; REGULATORY SEQUENCES, NUCLEIC ACID; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 22544440258     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0504378102     Document Type: Article

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