-
1
-
-
0033711184
-
The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137
-
P.A. Lyons, W.W. Hancock, and P. Denny The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137 Immunity 13 2000 107 115
-
(2000)
Immunity
, vol.13
, pp. 107-115
-
-
Lyons, P.A.1
Hancock, W.W.2
Denny, P.3
-
2
-
-
0035237619
-
Genes and cellular requirements for autoimmune diabetes susceptibility in nonobese diabetic mice
-
D.V. Serreze, and E.H. Leiter Genes and cellular requirements for autoimmune diabetes susceptibility in nonobese diabetic mice Curr Dir Autoimmun 4 2001 31 67
-
(2001)
Curr Dir Autoimmun
, vol.4
, pp. 31-67
-
-
Serreze, D.V.1
Leiter, E.H.2
-
3
-
-
0141609073
-
Co-stimulatory members of the TNFR family: Keys to effective T-cell immunity?
-
M. Croft Co-stimulatory members of the TNFR family: keys to effective T-cell immunity? Nat Rev Immunol 3 2003 609 620
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 609-620
-
-
Croft, M.1
-
4
-
-
17644389199
-
TNF/TNFR family members in costimulation of T cell responses
-
T.H. Watts TNF/TNFR family members in costimulation of T cell responses Annu Rev Immunol 23 2005 23 68
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 23-68
-
-
Watts, T.H.1
-
5
-
-
0035423265
-
4-1BBL induces cell division, sustains survival and enhances effector function of CD4 and CD8 T cells with similar efficacy
-
J.L. Cannons, P. Lau, and B. Ghumman 4-1BBL induces cell division, sustains survival and enhances effector function of CD4 and CD8 T cells with similar efficacy J Immunol 167 2001 1313 1324
-
(2001)
J Immunol
, vol.167
, pp. 1313-1324
-
-
Cannons, J.L.1
Lau, P.2
Ghumman, B.3
-
6
-
-
0032754036
-
Analysis of 4-1BB ligand-deficient mice and of mice lacking both 4-1BB ligand and CD28 reveals a role for 4-1BB ligand in skin allograft rejection and in the cytotoxic T cell response to influenza virus
-
M.A. DeBenedette, T. Wen, and M.F. Bachmann Analysis of 4-1BB ligand-deficient mice and of mice lacking both 4-1BB ligand and CD28 reveals a role for 4-1BB ligand in skin allograft rejection and in the cytotoxic T cell response to influenza virus J Immunol 163 1999 4833 4841
-
(1999)
J Immunol
, vol.163
, pp. 4833-4841
-
-
Debenedette, M.A.1
Wen, T.2
Bachmann, M.F.3
-
7
-
-
0032711836
-
4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses
-
J.T. Tan, J.K. Whitmire, R. Ahmed, T.C. Pearson, and C.P. Larsen 4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses J Immunol 163 1999 4859 4868
-
(1999)
J Immunol
, vol.163
, pp. 4859-4868
-
-
Tan, J.T.1
Whitmire, J.K.2
Ahmed, R.3
Pearson, T.C.4
Larsen, C.P.5
-
8
-
-
0036604470
-
Immune responses in 4-1BB (CD137)-deficient mice
-
B.S. Kwon, J.C. Hurtado, and Z.H. Lee Immune responses in 4-1BB (CD137)-deficient mice J Immunol 168 2002 5483 5490
-
(2002)
J Immunol
, vol.168
, pp. 5483-5490
-
-
Kwon, B.S.1
Hurtado, J.C.2
Lee, Z.H.3
-
9
-
-
0030845586
-
+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses
-
+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses J Exp Med 186 1997 47 55
-
(1997)
J Exp Med
, vol.186
, pp. 47-55
-
-
Shuford, W.W.1
Klussman, K.2
Tritchler, D.D.3
-
10
-
-
0031007143
-
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
-
I. Melero, W.W. Shuford, and S.A. Newby Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors Nat Med 3 1997 682 685
-
(1997)
Nat Med
, vol.3
, pp. 682-685
-
-
Melero, I.1
Shuford, W.W.2
Newby, S.A.3
-
11
-
-
0036075444
-
In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses
-
E.S. Halstead, Y.M. Mueller, J.D. Altman, and P.D. Katsikis In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses Nat Immunol 3 2002 536 541
-
(2002)
Nat Immunol
, vol.3
, pp. 536-541
-
-
Halstead, E.S.1
Mueller, Y.M.2
Altman, J.D.3
Katsikis, P.D.4
-
12
-
-
0842268271
-
A switch in costimulation from CD28 to 4-1BB during primary versus secondary CD8 T cell response to influenza in vivo
-
E.M. Bertram, W. Dawicki, B. Sedgmen, J.L. Bramson, D.H. Lynch, and T.H. Watts A switch in costimulation from CD28 to 4-1BB during primary versus secondary CD8 T cell response to influenza in vivo J Immunol 172 2004 981 988
-
(2004)
J Immunol
, vol.172
, pp. 981-988
-
-
Bertram, E.M.1
Dawicki, W.2
Sedgmen, B.3
Bramson, J.L.4
Lynch, D.H.5
Watts, T.H.6
-
13
-
-
0037090182
-
In vivo triggering through 4-1BB enables Th-independent priming of CTL in the presence of an intact CD28 costimulatory pathway
-
L. Diehl, G.J. van Mierlo, and A.T. den Boer In vivo triggering through 4-1BB enables Th-independent priming of CTL in the presence of an intact CD28 costimulatory pathway J Immunol 168 2002 3755 3762
-
(2002)
J Immunol
, vol.168
, pp. 3755-3762
-
-
Diehl, L.1
Van Mierlo, G.J.2
Den Boer, A.T.3
-
14
-
-
0036909587
-
Expression and costimulatory effects of the TNF receptor superfamily members CD134 (OX40) and CD137 (4-1BB), and their role in the generation of anti-tumor immune responses
-
V.Y. Taraban, T.F. Rowley, and L. O'Brien Expression and costimulatory effects of the TNF receptor superfamily members CD134 (OX40) and CD137 (4-1BB), and their role in the generation of anti-tumor immune responses Eur J Immunol 32 2002 3617 3627
-
(2002)
Eur J Immunol
, vol.32
, pp. 3617-3627
-
-
Taraban, V.Y.1
Rowley, T.F.2
O'Brien, L.3
-
15
-
-
0037096878
-
Anti-4-1BB monoclonal antibody enhances rejection of large tumor burden by promoting survival but not clonal expansion of tumor-specific CD8+ T cells
-
K.F. May Jr., L. Chen, P. Zheng, and Y. Liu Anti-4-1BB monoclonal antibody enhances rejection of large tumor burden by promoting survival but not clonal expansion of tumor-specific CD8+ T cells Cancer Res 62 2002 3459 3465
-
(2002)
Cancer Res
, vol.62
, pp. 3459-3465
-
-
May Jr., K.F.1
Chen, L.2
Zheng, P.3
Liu, Y.4
-
16
-
-
0035284861
-
Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients
-
B.R. Blazar, B.S. Kwon, A. Panoskaltsis-Mortari, K.B. Kwak, J.J. Peschon, and P.A. Taylor Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients J Immunol 166 2001 3174 3183
-
(2001)
J Immunol
, vol.166
, pp. 3174-3183
-
-
Blazar, B.R.1
Kwon, B.S.2
Panoskaltsis-Mortari, A.3
Kwak, K.B.4
Peschon, J.J.5
Taylor, P.A.6
-
17
-
-
0033571176
-
Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy
-
R.S. Mittler, T.S. Bailey, K. Klussman, M.D. Trailsmith, and M.K. Hoffmann Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy J Exp Med 190 1999 1535 1540
-
(1999)
J Exp Med
, vol.190
, pp. 1535-1540
-
-
Mittler, R.S.1
Bailey, T.S.2
Klussman, K.3
Trailsmith, M.D.4
Hoffmann, M.K.5
-
18
-
-
0036913169
-
Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease
-
Y. Sun, H.M. Chen, and S.K. Subudhi Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease Nat Med 8 2002 1405 1413
-
(2002)
Nat Med
, vol.8
, pp. 1405-1413
-
-
Sun, Y.1
Chen, H.M.2
Subudhi, S.K.3
-
19
-
-
0036467421
-
Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis
-
Y. Sun, X. Lin, and H.M. Chen Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis J Immunol 168 2002 1457 1465
-
(2002)
J Immunol
, vol.168
, pp. 1457-1465
-
-
Sun, Y.1
Lin, X.2
Chen, H.M.3
-
20
-
-
0038312910
-
CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB × NZW F1 mice
-
J. Foell, S. Strahotin, and S.P. O'Neil CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB × NZW F1 mice J Clin Invest 111 2003 1505 1518
-
(2003)
J Clin Invest
, vol.111
, pp. 1505-1518
-
-
Foell, J.1
Strahotin, S.2
O'Neil, S.P.3
-
21
-
-
0037223114
-
4-1BB (CD137) differentially regulates murine in vivo protein- and polysaccharide-specific immunoglobulin isotype responses to Streptococcus pneumoniae
-
Z.Q. Wu, A.Q. Khan, and Y. Shen 4-1BB (CD137) differentially regulates murine in vivo protein- and polysaccharide-specific immunoglobulin isotype responses to Streptococcus pneumoniae Infect Immun 71 2003 196 204
-
(2003)
Infect Immun
, vol.71
, pp. 196-204
-
-
Wu, Z.Q.1
Khan, A.Q.2
Shen, Y.3
-
22
-
-
0032101119
-
CD28-independent, TRAF2-dependent costimulation of resting T cells by 4-1BB ligand
-
K. Saoulli, S.Y. Lee, and J.L. Cannons CD28-independent, TRAF2-dependent costimulation of resting T cells by 4-1BB ligand J Exp Med 187 1998 1849 1862
-
(1998)
J Exp Med
, vol.187
, pp. 1849-1862
-
-
Saoulli, K.1
Lee, S.Y.2
Cannons, J.L.3
-
23
-
-
0031962348
-
4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor κb
-
R.H. Arch, and C.B. Thompson 4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor κB Mol Cell Biol 18 1998 558 565
-
(1998)
Mol Cell Biol
, vol.18
, pp. 558-565
-
-
Arch, R.H.1
Thompson, C.B.2
-
24
-
-
0033567975
-
Role of the stress kinase pathway in signaling via the T cell costimulatory receptor 4-1BB
-
J.L. Cannons, K.P. Hoeflich, J.R. Woodgett, and T.H. Watts Role of the stress kinase pathway in signaling via the T cell costimulatory receptor 4-1BB J Immunol 163 1999 2990 2998
-
(1999)
J Immunol
, vol.163
, pp. 2990-2998
-
-
Cannons, J.L.1
Hoeflich, K.P.2
Woodgett, J.R.3
Watts, T.H.4
-
25
-
-
0034541168
-
Role of TNF receptor-associated factor 2 and p38 mitogen-activated protein kinase activation during 4-1BB-dependent immune response
-
J.L. Cannons, Y. Choi, and T.H. Watts Role of TNF receptor-associated factor 2 and p38 mitogen-activated protein kinase activation during 4-1BB-dependent immune response J Immunol 165 2000 6193 6204
-
(2000)
J Immunol
, vol.165
, pp. 6193-6204
-
-
Cannons, J.L.1
Choi, Y.2
Watts, T.H.3
-
26
-
-
0036838689
-
4-1BB promotes the survival of CD8(+) T lymphocytes by increasing expression of Bcl-x(L) and Bfl-1
-
H.W. Lee, S.J. Park, B.K. Choi, H.H. Kim, K.O. Nam, and B.S. Kwon 4-1BB promotes the survival of CD8(+) T lymphocytes by increasing expression of Bcl-x(L) and Bfl-1 J Immunol 169 2002 4882 4888
-
(2002)
J Immunol
, vol.169
, pp. 4882-4888
-
-
Lee, H.W.1
Park, S.J.2
Choi, B.K.3
Kim, H.H.4
Nam, K.O.5
Kwon, B.S.6
-
27
-
-
0037220831
-
The derivation of highly germline-competent embryonic stem cells containing NOD-derived genome
-
F.A. Brook, E.P. Evans, and C.J. Lord The derivation of highly germline-competent embryonic stem cells containing NOD-derived genome Diabetes 52 2003 205 208
-
(2003)
Diabetes
, vol.52
, pp. 205-208
-
-
Brook, F.A.1
Evans, E.P.2
Lord, C.J.3
-
28
-
-
0037627478
-
Effector CD8 T cells possess suppressor function after 4-1BB and Toll-like receptor triggering
-
L. Myers, C. Takahashi, R.S. Mittler, R.J. Rossi, and A.T. Vella Effector CD8 T cells possess suppressor function after 4-1BB and Toll-like receptor triggering Proc Natl Acad Sci U S A 100 2003 5348 5353
-
(2003)
Proc Natl Acad Sci U S a
, vol.100
, pp. 5348-5353
-
-
Myers, L.1
Takahashi, C.2
Mittler, R.S.3
Rossi, R.J.4
Vella, A.T.5
-
29
-
-
7044261952
-
4-1BB-mediated immunotherapy of rheumatoid arthritis
-
S.K. Seo, J.H. Choi, and Y.H. Kim 4-1BB-mediated immunotherapy of rheumatoid arthritis Nat Med 10 2004 1088 1094
-
(2004)
Nat Med
, vol.10
, pp. 1088-1094
-
-
Seo, S.K.1
Choi, J.H.2
Kim, Y.H.3
-
30
-
-
4043089873
-
The 4-1BB costimulation augments the proliferation of CD4+CD25+ regulatory T cells
-
G. Zheng, B. Wang, and A. Chen The 4-1BB costimulation augments the proliferation of CD4+CD25+ regulatory T cells J Immunol 173 2004 2428 2434
-
(2004)
J Immunol
, vol.173
, pp. 2428-2434
-
-
Zheng, G.1
Wang, B.2
Chen, A.3
-
31
-
-
2342481815
-
4-1BB-dependent inhibition of immunosuppression by activated CD4+CD25+ T cells
-
B.K. Choi, J.S. Bae, and E.M. Choi 4-1BB-dependent inhibition of immunosuppression by activated CD4+CD25+ T cells J Leukoc Biol 75 2004 785 791
-
(2004)
J Leukoc Biol
, vol.75
, pp. 785-791
-
-
Choi, B.K.1
Bae, J.S.2
Choi, E.M.3
|