-
2
-
-
0025875259
-
Lpr and gld: Single gene models of systemic autoimmunity and lymphoproliferative disease
-
Cohen, P.L. & Eisenberg, R.A. Lpr and gld: Single gene models of systemic autoimmunity and lymphoproliferative disease. Annu. Rev. Immunol. 9, 243-269 (1991).
-
(1991)
Annu. Rev. Immunol.
, vol.9
, pp. 243-269
-
-
Cohen, P.L.1
Eisenberg, R.A.2
-
3
-
-
0021246171
-
The proliferating cells in autoimmune MRL/lpr mice lack L3T4, an antigen on "helper" T cells that is involved in the response to class II major histocompatibility antigens
-
Wofsy, D., Hardy, R.R. & Seaman, W.E. The proliferating cells in autoimmune MRL/lpr mice lack L3T4, an antigen on "helper" T cells that is involved in the response to class II major histocompatibility antigens. J. Immunol. 132, 2686-2689 (1984).
-
(1984)
J. Immunol.
, vol.132
, pp. 2686-2689
-
-
Wofsy, D.1
Hardy, R.R.2
Seaman, W.E.3
-
4
-
-
0020375486
-
Abnormalities induced by the mutant gene lpr: Expansion of a unique lymphocyte subset
-
Morse, H.C. 3rd et al. Abnormalities induced by the mutant gene lpr: Expansion of a unique lymphocyte subset. J. Immunol. 129, 2612-2615 (1982).
-
(1982)
J. Immunol.
, vol.129
, pp. 2612-2615
-
-
Morse H.C. III1
-
5
-
-
0018072901
-
Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains
-
Andrews, B.S. et al. Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains. J. Exp. Med. 148, 1198-1215 (1978).
-
(1978)
J. Exp. Med.
, vol.148
, pp. 1198-1215
-
-
Andrews, B.S.1
-
6
-
-
0033562983
-
Antigen-specific therapy of murine lupus nephritis using nucleosomal peptides: Tolerance spreading impairs pathogenic function of autoimmune T and B cells
-
Kaliyaperumal, A., Michaels, M.A. & Datta, S.K. Antigen-specific therapy of murine lupus nephritis using nucleosomal peptides: Tolerance spreading impairs pathogenic function of autoimmune T and B cells. J. Immunol. 162, 5775-5783 (1999).
-
(1999)
J. Immunol.
, vol.162
, pp. 5775-5783
-
-
Kaliyaperumal, A.1
Michaels, M.A.2
Datta, S.K.3
-
7
-
-
0027343886
-
Treatment of murine lupus with anti-CD4 monoclonal antibodies
-
Wofsy, D. Treatment of murine lupus with anti-CD4 monoclonal antibodies. Immunol. Ser. 59, 221-236 (1993).
-
(1993)
Immunol. Ser.
, vol.59
, pp. 221-236
-
-
Wofsy, D.1
-
8
-
-
0028852328
-
Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis
-
Mohan, C., Shi, Y., Laman, J.D. & Datta, S.K. Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis. J. Immunol. 154, 1470-80 (1995).
-
(1995)
J. Immunol.
, vol.154
, pp. 1470-1480
-
-
Mohan, C.1
Shi, Y.2
Laman, J.D.3
Datta, S.K.4
-
9
-
-
0028483990
-
Treatment of murine lupus with CTLA4Ig
-
Finck, B.K., Linsley, P.S. & Wofsy, D. Treatment of murine lupus with CTLA4Ig. Science 265, 1225-1227 (1994).
-
(1994)
Science
, vol.265
, pp. 1225-1227
-
-
Finck, B.K.1
Linsley, P.S.2
Wofsy, D.3
-
10
-
-
0032030667
-
Anti-CD40 ligand antibody treatment of SNF1 mice with established nephritis: Preservation of kidney function
-
Kalled, S.L., Cutler, A.H., Datta, S.K. & Thomas, D.W. Anti-CD40 ligand antibody treatment of SNF1 mice with established nephritis: Preservation of kidney function. J. Immunol. 160, 2158-2165 (1998).
-
(1998)
J. Immunol.
, vol.160
, pp. 2158-2165
-
-
Kalled, S.L.1
Cutler, A.H.2
Datta, S.K.3
Thomas, D.W.4
-
11
-
-
0034665384
-
Autoantibody responses and pathology regulated by B7-1 and B7-2 costimulation in MRL/lpr lupus
-
Liang, B., Kashgarian, M.J., Sharpe, A.H. & Mamula, M.I. Autoantibody responses and pathology regulated by B7-1 and B7-2 costimulation in MRL/lpr lupus. J. Immunol. 165, 3436-3443 (2000).
-
(2000)
J. Immunol.
, vol.165
, pp. 3436-3443
-
-
Liang, B.1
Kashgarian, M.J.2
Sharpe, A.H.3
Mamula, M.I.4
-
12
-
-
0032725836
-
Tumour necrosis factor and other cytokines in murine lupus
-
Theofilopoulos, A.N. & Lawson, B.R. Tumour necrosis factor and other cytokines in murine lupus. Ann. Rheum. Dis. 58 Suppl. 1, 149-55 (1999).
-
(1999)
Ann. Rheum. Dis.
, vol.58
, Issue.SUPPL. 1
, pp. 149-155
-
-
Theofilopoulos, A.N.1
Lawson, B.R.2
-
13
-
-
0032936962
-
Cytokines in the pathogenesis of systemic lupus erythematosus
-
Kelley, V.R. & Wuthrich, R.P. Cytokines in the pathogenesis of systemic lupus erythematosus. Semin. Nephrol. 19, 57-66 (1999).
-
(1999)
Semin. Nephrol.
, vol.19
, pp. 57-66
-
-
Kelley, V.R.1
Wuthrich, R.P.2
-
14
-
-
0033942181
-
Treatment of murine lupus with cDNA encoding IFN-γR/Fc
-
Lawson, B.R. et al. Treatment of murine lupus with cDNA encoding IFN-γR/Fc. J. Clin. Invest. 106, 207-215 (2000).
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 207-215
-
-
Lawson, B.R.1
-
15
-
-
0032374052
-
Role of 4-1BB in immune responses
-
Vinay, D.S. & Kwon, B.S. Role of 4-1BB in immune responses. Semin. Immunol. 10, 481-489 (1998).
-
(1998)
Semin. Immunol.
, vol.10
, pp. 481-489
-
-
Vinay, D.S.1
Kwon, B.S.2
-
16
-
-
0034732379
-
4-1BB: Still in the midst of darkness
-
Kwon, B., Moon, C.H., Kang, S., Seo, S.K. & Kwon, B.S. 4-1BB: Still in the midst of darkness. Mol. Cells 10, 119-126 (2000).
-
(2000)
Mol. Cells
, vol.10
, pp. 119-126
-
-
Kwon, B.1
Moon, C.H.2
Kang, S.3
Seo, S.K.4
Kwon, B.S.5
-
17
-
-
0027285735
-
Inducible T cell antigen 4-1BB. Analysis of expression and function
-
Pollok, K.E. et al. Inducible T cell antigen 4-1BB. Analysis of expression and function. J. Immunol. 150, 771-781 (1993).
-
(1993)
J. Immunol.
, vol.150
, pp. 771-781
-
-
Pollok, K.E.1
-
18
-
-
0032535119
-
NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies
-
Melero, I., Johnston, J.V., Shufford, W.W., Mittler, R.S. & Chen, L. NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies. Cell. Immunol. 190, 167-172 (1998).
-
(1998)
Cell. Immunol.
, vol.190
, pp. 167-172
-
-
Melero, I.1
Johnston, J.V.2
Shufford, W.W.3
Mittler, R.S.4
Chen, L.5
-
19
-
-
0027365746
-
Molecular cloning of a ligand for the inducible T cell gene 4-1BB: A member of an emerging family of cytokines with homology to tumor necrosis factor
-
Goodwin, R.G. et al. Molecular cloning of a ligand for the inducible T cell gene 4-1BB: A member of an emerging family of cytokines with homology to tumor necrosis factor. Eur. J. Immunol. 23, 2631-2641 (1993).
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 2631-2641
-
-
Goodwin, R.G.1
-
20
-
-
0028009709
-
4-1BB T-cell antigen binds to mature B cells and macrophages, and costimulates anti-μ-primed splenic B cells
-
Pollok, K.E. et al. 4-1BB T-cell antigen binds to mature B cells and macrophages, and costimulates anti-μ-primed splenic B cells. Eur. J. Immunol. 24, 367-374 (1994).
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 367-374
-
-
Pollok, K.E.1
-
21
-
-
20244386539
-
Molecular and biological characterization of human 4-1BB and its ligand
-
Alderson, M.R. et al. Molecular and biological characterization of human 4-1BB and its ligand. Eur. J. Immunol. 24, 2219-2227 (1994).
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 2219-2227
-
-
Alderson, M.R.1
-
22
-
-
0031007143
-
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
-
Melero, I. et al. Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors. Nature Med. 3, 682-685 (1997).
-
(1997)
Nature Med.
, vol.3
, pp. 682-685
-
-
Melero, I.1
-
23
-
-
0030845586
-
+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses
-
+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses. J. Exp. Med. 186, 47-55 (1997).
-
(1997)
J. Exp. Med.
, vol.186
, pp. 47-55
-
-
Shuford, W.W.1
-
24
-
-
0035284861
-
Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients
-
Blazar, B.R. et al. Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients. J. Immunol. 166, 3174-3183 (2001).
-
(2001)
J. Immunol.
, vol.166
, pp. 3174-3183
-
-
Blazar, B.R.1
-
25
-
-
0036195860
-
Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors
-
Wilcox, R. et al. Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors. J. Clin. Invest. 109, 651-659 (2002).
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 651-659
-
-
Wilcox, R.1
-
27
-
-
0033571176
-
Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy
-
Mittler, R.S., Bailey, T.S., Klussman, K., Trailsmith, M.D. & Hoffmann, M.K. Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy. J. Exp. Med. 190, 1535-1540 (1999).
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1535-1540
-
-
Mittler, R.S.1
Bailey, T.S.2
Klussman, K.3
Trailsmith, M.D.4
Hoffmann, M.K.5
-
28
-
-
0036467421
-
Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis
-
Sun, Y. et al. Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis. J. Immunol. 168, 1457-1465 (2002).
-
(2002)
J. Immunol.
, vol.168
, pp. 1457-1465
-
-
Sun, Y.1
-
29
-
-
0027477302
-
Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice
-
Adachi, M., Watanabe-Fukunaga, R. & Nagata, S. Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice. Proc. Natl. Acad. Sci. USA 90, 1756-1760 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 1756-1760
-
-
Adachi, M.1
Watanabe-Fukunaga, R.2
Nagata, S.3
-
30
-
-
0031398761
-
Why do defects in the Fas-Fas ligand system cause autoimmunity?
-
Suda, T. & Nagata, S. Why do defects in the Fas-Fas ligand system cause autoimmunity? J. Allergy Clin. Immunol. 100, S97-101 (1997).
-
(1997)
J. Allergy Clin. Immunol.
, vol.100
-
-
Suda, T.1
Nagata, S.2
-
31
-
-
0033151622
-
Reactive oxygen species regulate activation-induced T cell apoptosis
-
Hildeman, D.A. et al. Reactive oxygen species regulate activation-induced T cell apoptosis. Immunity 10, 73S-744 (1999).
-
(1999)
Immunity
, vol.10
-
-
Hildeman, D.A.1
-
32
-
-
0023706894
-
Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production
-
Ding, A.H., Nathan, C.F. & Stuehr, D.J. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J. Immunol. 141, 2407-2412 (1988).
-
(1988)
J. Immunol.
, vol.141
, pp. 2407-2412
-
-
Ding, A.H.1
Nathan, C.F.2
Stuehr, D.J.3
-
33
-
-
0032534664
-
Nitric oxide synthase plays a signaling role in TCR-triggered apoptotic death
-
Williams, M.S., Noguchi, S., Henkart, P.A. & Osawa, Y. Nitric oxide synthase plays a signaling role in TCR-triggered apoptotic death. J. Immunol. 161, 6526-6531 (1998).
-
(1998)
J. Immunol.
, vol.161
, pp. 6526-6531
-
-
Williams, M.S.1
Noguchi, S.2
Henkart, P.A.3
Osawa, Y.4
-
34
-
-
0032618798
-
Nitric oxide and apoptosis
-
Haendeler, J., Zeiher, A.M. & Dimmeler, S. Nitric oxide and apoptosis. Vitam. Horm. 57, 49-77 (1999).
-
(1999)
Vitam. Horm.
, vol.57
, pp. 49-77
-
-
Haendeler, J.1
Zeiher, A.M.2
Dimmeler, S.3
-
35
-
-
0024215452
-
Local extrahepatic expression of complement genes C3, factor 8, C2, and C4 is increased in murine lupus nephritis
-
Passwell, J., Schreiner, G.F., Nonaka, M., Beuscher, H.U. & Colten, H.R. Local extrahepatic expression of complement genes C3, factor 8, C2, and C4 is increased in murine lupus nephritis. J. Clin. Invest. 82, 1676-1684 (1988).
-
(1988)
J. Clin. Invest.
, vol.82
, pp. 1676-1684
-
-
Passwell, J.1
Schreiner, G.F.2
Nonaka, M.3
Beuscher, H.U.4
Colten, H.R.5
-
36
-
-
0035487709
-
T cells in the pathogenesis of systemic lupus erythematosus
-
Hoffman, R.W. T cells in the pathogenesis of systemic lupus erythematosus. Front Biosci. 6, D1369-1378 (2001).
-
(2001)
Front Biosci.
, vol.6
-
-
Hoffman, R.W.1
-
37
-
-
0030944143
-
Unique site of IgG2a and rheumatoid factor production in MRL/lpr mice
-
Jacobson, B.A., Rothstein, T.L. & Marshak-Rothstein, A. Unique site of IgG2a and rheumatoid factor production in MRL/lpr mice. Immunol. Rev. 156, 103-110 (1997).
-
(1997)
Immunol. Rev.
, vol.156
, pp. 103-110
-
-
Jacobson, B.A.1
Rothstein, T.L.2
Marshak-Rothstein, A.3
-
38
-
-
0030953632
-
Roles of interferon-γ and interleukin-4 in murine lupus
-
Peng, S.L., Moslehi, J. & Craft, J. Roles of interferon-γ and interleukin-4 in murine lupus. J. Clin. Invest. 99, 1936-1946 (1997).
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 1936-1946
-
-
Peng, S.L.1
Moslehi, J.2
Craft, J.3
-
39
-
-
0032518439
-
Interferon-γ is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice
-
Balomenos, D., Rumold, R. & Theofilopoulos, A.N. Interferon-γ is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice. J. Clin. Invest. 101, 364-371 (1998).
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 364-371
-
-
Balomenos, D.1
Rumold, R.2
Theofilopoulos, A.N.3
-
40
-
-
0031155269
-
IFN-γ is essential for the development of autoimmune glomerulonephritis in MRL/lpr mice
-
Haas, C., Ryffel, B. & Le Hir, M. IFN-γ is essential for the development of autoimmune glomerulonephritis in MRL/lpr mice. J. Immunol. 158, 5484-5491 (1997).
-
(1997)
J. Immunol.
, vol.158
, pp. 5484-5491
-
-
Haas, C.1
Ryffel, B.2
Le Hir, M.3
-
41
-
-
0031831859
-
IFN-γ receptor signaling is essential for the initiation, acceleration, and destruction of autoimmune kidney disease in MRL-Fas(lpr) mice
-
Schwarting, A., Wada, T., Kinoshita, K., Tesch, G. & Kelley, V.R. IFN-γ receptor signaling is essential for the initiation, acceleration, and destruction of autoimmune kidney disease in MRL-Fas(lpr) mice. J. Immunol. 161, 494-503 (1998).
-
(1998)
J. Immunol.
, vol.161
, pp. 494-503
-
-
Schwarting, A.1
Wada, T.2
Kinoshita, K.3
Tesch, G.4
Kelley, V.R.5
-
42
-
-
0033976316
-
Dichotomic effects of IFN-γ on the development of systemic lupus erythematosus-like syndrome in MRL-lpr/lpr mice
-
Nicoletti, F. et al. Dichotomic effects of IFN-γ on the development of systemic lupus erythematosus-like syndrome in MRL-lpr/lpr mice. Eur. J. Immunol. 30, 438-447 (2000).
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 438-447
-
-
Nicoletti, F.1
-
43
-
-
0035660806
-
The regulation of T cell homeostasis and autoimmunity by T cell-derived LIGHT
-
Wang, J. et al. The regulation of T cell homeostasis and autoimmunity by T cell-derived LIGHT. J. Clin. Invest. 108, 1771-1780 (2001).
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1771-1780
-
-
Wang, J.1
|