-
1
-
-
0028962125
-
Fas-mediated cytotoxicity by freshly isolated natural killer cells
-
Arase, H., N. Arase, and T. Saito. 1995. Fas-mediated cytotoxicity by freshly isolated natural killer cells. J. Exp. Med. 181:1235-1238.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1235-1238
-
-
Arase, H.1
Arase, N.2
Saito, T.3
-
2
-
-
84983711696
-
Studies on the chemical nature of the substance inducing transformation of pneumococcal types. Induction of transformation by a deoxyribonucleic acid fraction isolated from pneumococcus type III
-
Avery, O. T., C. M. MacLeod, and M. McCarty. 1944. Studies on the chemical nature of the substance inducing transformation of pneumococcal types. Induction of transformation by a deoxyribonucleic acid fraction isolated from pneumococcus type III. J. Exp. Med. 79:137-145.
-
(1944)
J. Exp. Med.
, vol.79
, pp. 137-145
-
-
Avery, O.T.1
MacLeod, C.M.2
McCarty, M.3
-
3
-
-
0037090337
-
Temporal segregation of 4-1BB versus CD28-mediated costimulation: 4-1BB ligand influences T cell numbers late in the primary response and regulates the size of the T cell memory response following influenza infection
-
Bertram, E. M., P. Lau, and T. H. Watts. 2002. Temporal segregation of 4-1BB versus CD28-mediated costimulation: 4-1BB ligand influences T cell numbers late in the primary response and regulates the size of the T cell memory response following influenza infection. J. Immunol. 168:3777-3785.
-
(2002)
J. Immunol.
, vol.168
, pp. 3777-3785
-
-
Bertram, E.M.1
Lau, P.2
Watts, T.H.3
-
4
-
-
0035284861
-
Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients
-
Blazar, B. R., B. S. Kwon, A. Panoskaltsis-Mortari, K. B. Kwak, J. J. Peschon, and P. A. Taylor. 2001. Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients. J. Immunol. 166:3174-3183.
-
(2001)
J. Immunol.
, vol.166
, pp. 3174-3183
-
-
Blazar, B.R.1
Kwon, B.S.2
Panoskaltsis-Mortari, A.3
Kwak, K.B.4
Peschon, J.J.5
Taylor, P.A.6
-
6
-
-
0030998508
-
Regulation of B lymphocytes by dendritic cells
-
Clark, E. A. 1997. Regulation of B lymphocytes by dendritic cells. J. Exp. Med. 185:801-803.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 801-803
-
-
Clark, E.A.1
-
7
-
-
0037033281
-
Dendritic cells pulsed with intact Streptococcus pneumoniae elicit both protein- and polysaccharide-specific immunoglobulin isotype responses in vivo through distinct mechanisms
-
Colino, J., Y. Shen, and C. M. Snapper. 2002. Dendritic cells pulsed with intact Streptococcus pneumoniae elicit both protein- and polysaccharide-specific immunoglobulin isotype responses in vivo through distinct mechanisms. J. Exp. Med. 195:1-13.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1-13
-
-
Colino, J.1
Shen, Y.2
Snapper, C.M.3
-
8
-
-
0035292756
-
The expanding B7 superfamily increasing complexity in costimulatory signals regulating T cell function
-
Coyle, A. J., and J. C. Gutierrez-Ramos. 2001. The expanding B7 superfamily increasing complexity in costimulatory signals regulating T cell function. Nat. Immunol. 2:203-209.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 203-209
-
-
Coyle, A.J.1
Gutierrez-Ramos, J.C.2
-
9
-
-
0031567896
-
Costimuiation of CD28-T lymphocytes by 4-1BB ligand
-
DeBenedette, M. A., A. Shahinian, T. W. Mak, and T. H. Watts. 1997. Costimuiation of CD28-T lymphocytes by 4-1BB ligand. J. Immunol. 158:551-559.
-
(1997)
J. Immunol.
, vol.158
, pp. 551-559
-
-
DeBenedette, M.A.1
Shahinian, A.2
Mak, T.W.3
Watts, T.H.4
-
10
-
-
0032754036
-
Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus
-
DeBenedette, M. A., T. Wen, M. F. Bachmann, P. S. Ohashi, B. H. Barber, K. L. Stocking, J. J. Peschon, and T. H. Watts. 1999. Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus. J. Immunol. 163:4833-4841.
-
(1999)
J. Immunol.
, vol.163
, pp. 4833-4841
-
-
DeBenedette, M.A.1
Wen, T.2
Bachmann, M.F.3
Ohashi, P.S.4
Barber, B.H.5
Stocking, K.L.6
Peschon, J.J.7
Watts, T.H.8
-
11
-
-
0037090182
-
In vivo triggering through 4-1BB enables Th-independent priming of CTL in the presence of an intact CD28 costimulatory pathway
-
Diehl, L., G. J. D. van Mierlo, A. T. den Boer, E. van der Voort, M. Fransen, L. van Bostelen, P. Krimpenfort, C. J. M. Melief, R. Mittler, R. E. M. Toes, and R. Offringa. 2002. In vivo triggering through 4-1BB enables Th-independent priming of CTL in the presence of an intact CD28 costimulatory pathway. J. Immunol. 168:3755-3762.
-
(2002)
J. Immunol.
, vol.168
, pp. 3755-3762
-
-
Diehl, L.1
Van Mierlo, G.J.D.2
Den Boer, A.T.3
Van der Voort, E.4
Fransen, M.5
Van Bostelen, L.6
Krimpenfort, P.7
Melief, C.J.M.8
Mittler, R.9
Toes, R.E.M.10
Offringa, R.11
-
12
-
-
0027365746
-
Molecular cloning of a ligand for the inducible T cell gene 4-1BB: A member of an emerging family of cytokines with homology to tumor necrosis factor
-
Goodwin, R. G., W. S. Din, T. Davis-Smith, D. M. Anderson, S. D. Gimpel, T. A. Sato, C. R. Maliszewski, C. I. Brannan, N. G. Copeland, N. A. Jenkins, et al. 1993. Molecular cloning of a ligand for the inducible T cell gene 4-1BB: A member of an emerging family of cytokines with homology to tumor necrosis factor. Eur. J. Immunol. 23:2631-2641.
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 2631-2641
-
-
Goodwin, R.G.1
Din, W.S.2
Davis-Smith, T.3
Anderson, D.M.4
Gimpel, S.D.5
Sato, T.A.6
Maliszewski, C.R.7
Brannan, C.I.8
Copeland, N.G.9
Jenkins, N.A.10
-
13
-
-
0032030619
-
Generation of an inhibitory circuit involving CD8+ T cells, IL-2, and NK cell-derived TGF-β: Contrasting effects of anti-CD2 and anti-CD3
-
Gray, J. D., M. Hirokawa, K. Ohtsuka, and D. A. Horwitz. 1998. Generation of an inhibitory circuit involving CD8+ T cells, IL-2, and NK cell-derived TGF-β: Contrasting effects of anti-CD2 and anti-CD3. J. Immunol. 160:2248-2254.
-
(1998)
J. Immunol.
, vol.160
, pp. 2248-2254
-
-
Gray, J.D.1
Hirokawa, M.2
Ohtsuka, K.3
Horwitz, D.A.4
-
14
-
-
0027761138
-
Identificaion of an alternative CTLA-4 ligand costimulatory for T cell activation
-
Hatchcock, K. S., G. Laszlo, H. B. Dickler, J. Bradshaw, P. Linsley, and R. J. Hodes. 1993. Identificaion of an alternative CTLA-4 ligand costimulatory for T cell activation. Science 262:905-907.
-
(1993)
Science
, vol.262
, pp. 905-907
-
-
Hatchcock, K.S.1
Laszlo, G.2
Dickler, H.B.3
Bradshaw, J.4
Linsley, P.5
Hodes, R.J.6
-
15
-
-
0029117913
-
Potential role of 4-1BB in T cell activation: Comparison with the costimulatory molecule CD28
-
Hurtado, J. C., S. H. Kim, K. E. Pollok, Z. H. Lee, and B. S. Kwon. 1995. Potential role of 4-1BB in T cell activation: Comparison with the costimulatory molecule CD28. J. Immunol. 155:3360-3367.
-
(1995)
J. Immunol.
, vol.155
, pp. 3360-3367
-
-
Hurtado, J.C.1
Kim, S.H.2
Pollok, K.E.3
Lee, Z.H.4
Kwon, B.S.5
-
16
-
-
0036156077
-
Endogenous pro- and anti-inflammatory cytokines differentially regulate an in vivo humoral response to Streptococcus pneumoniae
-
Khan, A. Q., Y. Shen, Z. Q. Wu, T. A. Wynn, and C. M. Snapper. 2002. Endogenous pro- and anti-inflammatory cytokines differentially regulate an in vivo humoral response to Streptococcus pneumoniae. Infect. Immun. 70:749-761.
-
(2002)
Infect. Immun.
, vol.70
, pp. 749-761
-
-
Khan, A.Q.1
Shen, Y.2
Wu, Z.Q.3
Wynn, T.A.4
Snapper, C.M.5
-
17
-
-
0036604470
-
Immune responses in 4-1Bb (CD137)-deficient mice
-
Kwon, B. S., J. C. Hurtado, Z. H. Lee, K. B. Kwack, S. K. Seo, B. K. Choi, B. H. Koller, G. Wolisi, H. E. Broxmeyer, and D. S. Vinay. 2002. Immune responses in 4-1Bb (CD137)-deficient mice. J. Immunol. 168:5483-5490.
-
(2002)
J. Immunol.
, vol.168
, pp. 5483-5490
-
-
Kwon, B.S.1
Hurtado, J.C.2
Lee, Z.H.3
Kwack, K.B.4
Seo, S.K.5
Choi, B.K.6
Koller, B.H.7
Wolisi, G.8
Broxmeyer, H.E.9
Vinay, D.S.10
-
18
-
-
0032032236
-
CD137 (ILA/4-1BB), a member of the TNF receptor family, induces monocyte activation via bidirectioinal signaling
-
Langstein, J., J. Michel, J. Fritsche, M. Kreutz, R. Andreesen, and H. Schwarz. 1998. CD137 (ILA/4-1BB), a member of the TNF receptor family, induces monocyte activation via bidirectioinal signaling. J. Immunol. 160:2488-2494.
-
(1998)
J. Immunol.
, vol.160
, pp. 2488-2494
-
-
Langstein, J.1
Michel, J.2
Fritsche, J.3
Kreutz, M.4
Andreesen, R.5
Schwarz, H.6
-
19
-
-
0031007143
-
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
-
Melero, I., W. W. Shuford, S. A. Newby, A. Aruffo, J. A. Ledbetter, K. E. Hellstrom, R. S. Mittler, and L. Chen. 1997. Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors. Nat. Med. 3:682-685.
-
(1997)
Nat. Med.
, vol.3
, pp. 682-685
-
-
Melero, I.1
Shuford, W.W.2
Newby, S.A.3
Aruffo, A.4
Ledbetter, J.A.5
Hellstrom, K.E.6
Mittler, R.S.7
Chen, L.8
-
20
-
-
0032535119
-
NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies
-
Melero, I., J. V. Johnston, W. W. Shufford, R. S. Mittler, and L. Chen. 1998. NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies. Cell. Immunol. 190:167-172.
-
(1998)
Cell. Immunol.
, vol.190
, pp. 167-172
-
-
Melero, I.1
Johnston, J.V.2
Shufford, W.W.3
Mittler, R.S.4
Chen, L.5
-
21
-
-
0033571176
-
Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy
-
Mittler, R., T. Bailey, K. Klussman, M. Trailsmith, and M. Hoffmann. 1999. Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy. J. Exp. Med. 190:1535-1540.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1535-1540
-
-
Mittler, R.1
Bailey, T.2
Klussman, K.3
Trailsmith, M.4
Hoffmann, M.5
-
22
-
-
0003633755
-
-
Institute of Animal Resources, National Research Council, Washington, D.C
-
a.National Institutes of Health, Department of Health, Education, and Welfare. 1996. Guide for the Care and Use of Laboratory Animals. Standard 78-23. Institute of Animal Resources, National Research Council, Washington, D.C.
-
(1996)
Guide for the Care and Use of Laboratory Animals. Standard 78-23
-
-
-
23
-
-
0027285735
-
Inducible T cell antigen 4-1BB. Analysis of expression and function
-
Pollok, K. E., Y.-J. Kim, Z. Zhou, J. Hurtado, K. K. Kim, R. T. Pickard, and B. S. Kwon. 1993. Inducible T cell antigen 4-1BB. Analysis of expression and function. J. Immunol. 150:771-781.
-
(1993)
J. Immunol.
, vol.150
, pp. 771-781
-
-
Pollok, K.E.1
Kim, Y.-J.2
Zhou, Z.3
Hurtado, J.4
Kim, K.K.5
Pickard, R.T.6
Kwon, B.S.7
-
24
-
-
0028009709
-
4-1BB T-cell antigen binds to mature B cells and macrophage, and costimulates anti-μ-primed splenic B cells
-
Pollok, K. E., Y.-J. Kim, J. Hurtado, Z. Zhou, K. K. Kim, and B. S. Kwon. 1994. 4-1BB T-cell antigen binds to mature B cells and macrophage, and costimulates anti-μ-primed splenic B cells. Eur. J. Immunol. 24:367-374.
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 367-374
-
-
Pollok, K.E.1
Kim, Y.-J.2
Hurtado, J.3
Zhou, Z.4
Kim, K.K.5
Kwon, B.S.6
-
25
-
-
0027424137
-
Evidence for an additional ligand, distinct from B7, for the CTLA-4 receptor
-
Razi-Wolf, Z., F. Galvin, G. Gray, and H. Reiser. 1993. Evidence for an additional ligand, distinct from B7, for the CTLA-4 receptor. Proc. Natl. Acad. Sci. USA 90:11182-11186.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11182-11186
-
-
Razi-Wolf, Z.1
Galvin, F.2
Gray, G.3
Reiser, H.4
-
26
-
-
0028920079
-
Protection against fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells
-
Rothstein, T. L., J. K. M. Wang, D. J. Panka, L. C. Foote, Z. Wang, B. Stanger, H. Cui, S. Ju, and A. Marshak-Rothstein. 1995. Protection against fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells. Nature 374:163-165.
-
(1995)
Nature
, vol.374
, pp. 163-165
-
-
Rothstein, T.L.1
Wang, J.K.M.2
Panka, D.J.3
Foote, L.C.4
Wang, Z.5
Stanger, B.6
Cui, H.7
Ju, S.8
Marshak-Rothstein, A.9
-
27
-
-
0032101119
-
CD28-independent TRAF2-dependent costimulation of resting T cells by 4-1BB ligand
-
Saoulli, K., S. Y. Lee, J. L. Cannons, W. C. Yeh, A. Santana, M. D. Goldstein, N. Bangia, M. A. DeBenedette, T. W. Mak, Y. Choi, and T. H. Watts. 1998. CD28-independent TRAF2-dependent costimulation of resting T cells by 4-1BB ligand. J. Exp. Med. 187:1849-1862.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1849-1862
-
-
Saoulli, K.1
Lee, S.Y.2
Cannons, J.L.3
Yeh, W.C.4
Santana, A.5
Goldstein, M.D.6
Bangia, N.7
DeBenedette, M.A.8
Mak, T.W.9
Choi, Y.10
Watts, T.H.11
-
28
-
-
0030845586
-
+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses
-
+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses. J. Exp. Med. 186:47-55.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 47-55
-
-
Shuford, W.W.1
Klussman, K.2
Tritchler, D.D.3
Loo, D.T.4
Chalupny, J.5
Siadak, A.W.6
Brown, T.J.7
Emswiler, J.8
Raecho, H.9
Larsen, C.P.10
Pearson, T.C.11
Ledbetter, J.A.12
Aruffo, A.13
Mittler, R.S.14
-
29
-
-
0023197097
-
Interferon-γ and B cell stimulatory factor-1 reciprocally regulate Ig isotype production
-
Snapper, C. M., and W. E. Paul. 1987. Interferon-γ and B cell stimulatory factor-1 reciprocally regulate Ig isotype production. Science 236:944-947.
-
(1987)
Science
, vol.236
, pp. 944-947
-
-
Snapper, C.M.1
Paul, W.E.2
-
30
-
-
0026525387
-
Induction of IgG3 secretion by interferon γ: A model for T cell-independent class switching in response to T cell-independent type 2 antigens
-
Snapper, C. M., T. M. McIntyre, R. Mandler, L. M. T. Peçanha, F. D. Finkelman, A. Lees, and J. J. Mond. 1992. Induction of IgG3 secretion by interferon γ: A model for T cell-independent class switching in response to T cell-independent type 2 antigens. J. Exp. Med. 175:1367-1371.
-
(1992)
J. Exp. Med.
, vol.175
, pp. 1367-1371
-
-
Snapper, C.M.1
McIntyre, T.M.2
Mandler, R.3
Peçanha, L.M.T.4
Finkelman, F.D.5
Lees, A.6
Mond, J.J.7
-
31
-
-
0034920277
-
Distinct types of T-cell help for the induction of a humoral immune response to Streptococcus pneumoniae
-
Snapper, C. M., Y. Shen, A. Q. Khan, J. Colino, P. Zelazowski, J. J. Mond, W. C. Gause, and Z.-Q. Wu. 2001. Distinct types of T-cell help for the induction of a humoral immune response to Streptococcus pneumoniae. Trends Immunol. 22:308-311.
-
(2001)
Trends Immunol.
, vol.22
, pp. 308-311
-
-
Snapper, C.M.1
Shen, Y.2
Khan, A.Q.3
Colino, J.4
Zelazowski, P.5
Mond, J.J.6
Gause, W.C.7
Wu, Z.-Q.8
-
32
-
-
0032711836
-
4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses
-
Tan, J., J. Whitmire, Ahmed, R., T. Pearson, and C. Larsen. 1999. 4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses. J. Immunol. 163:4859-4868.
-
(1999)
J. Immunol.
, vol.163
, pp. 4859-4868
-
-
Tan, J.1
Whitmire, J.2
Ahmed, R.3
Pearson, T.4
Larsen, C.5
-
33
-
-
0034162569
-
4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination
-
Tan, J. T., J. K. Whitmire, K. Murali-Krishna, R. Ahmed, J. D. Altman, R. S. Mittler, A. Sette, T. C. Pearson, and C. P. Larsen. 2000. 4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination. J. Immunol. 164:2320-2325.
-
(2000)
J. Immunol.
, vol.164
, pp. 2320-2325
-
-
Tan, J.T.1
Whitmire, J.K.2
Murali-Krishna, K.3
Ahmed, R.4
Altman, J.D.5
Mittler, R.S.6
Sette, A.7
Pearson, T.C.8
Larsen, C.P.9
-
34
-
-
0036569392
-
Expression of functional CD137 receptor by dendritic cells
-
Wilcox, R. A., A. I. Chapoval, K. S. Gorski, M. Otsuji, T. Hin, D. B. Flies, K. Tamada, R. S. Mittler, H. Tsuchiya, D. M. Pardoll, and L. Chen. 2002. Expression of functional CD137 receptor by dendritic cells. J. Immunol. 168:4262-4267.
-
(2002)
J. Immunol.
, vol.168
, pp. 4262-4267
-
-
Wilcox, R.A.1
Chapoval, A.I.2
Gorski, K.S.3
Otsuji, M.4
Hin, T.5
Flies, D.B.6
Tamada, K.7
Mittler, R.S.8
Tsuchiya, H.9
Pardoll, D.M.10
Chen, L.11
-
35
-
-
0033565793
-
In vivo polysaccharide-specific IgG isotype responses to intact Streptococcus pneumoniae are T cell dependent and require CD40- and B7-ligand interactions
-
Wu, Z.-Q., Q. Vos, Y. Shen, A. Lees, S. R. Wilson, D. E. Briles, W. C. Gause, J. J. Mond, and C. M. Snapper. 1999. In vivo polysaccharide-specific IgG isotype responses to intact Streptococcus pneumoniae are T cell dependent and require CD40- and B7-ligand interactions. J. Immunol. 163:659-667.
-
(1999)
J. Immunol.
, vol.163
, pp. 659-667
-
-
Wu, Z.-Q.1
Vos, Q.2
Shen, Y.3
Lees, A.4
Wilson, S.R.5
Briles, D.E.6
Gause, W.C.7
Mond, J.J.8
Snapper, C.M.9
-
36
-
-
0034671567
-
B7 requirements for primary and secondary protein- and polysaccharide-specific Ig isotype responses to Streptococcus pneumoniae
-
Wu, Z. Q., A. Q. Khan, Y. Shen, J. Schartman, R. Peach, A. Lees, J. J. Mond, W. C. Gause, and C. M. Snapper. 2000. B7 requirements for primary and secondary protein- and polysaccharide-specific Ig isotype responses to Streptococcus pneumoniae. J. Immunol. 165:6840-6848.
-
(2000)
J. Immunol.
, vol.165
, pp. 6840-6848
-
-
Wu, Z.Q.1
Khan, A.Q.2
Shen, Y.3
Schartman, J.4
Peach, R.5
Lees, A.6
Mond, J.J.7
Gause, W.C.8
Snapper, C.M.9
-
37
-
-
0036604343
-
The mechanism underlying T cell help for induction of an antigen-specific in vivo humoral immune response to intact Streptococcus pneumoniae is dependent on the type of antigen
-
Wu, Z.-Q., Y. Shen, A. Q. Khan, C.-L. Chu, R. Riese, H. A. Chapman, O. Kanagawa, and C. M. Snapper. 2002. The mechanism underlying T cell help for induction of an antigen-specific in vivo humoral immune response to intact Streptococcus pneumoniae is dependent on the type of antigen. J. Immunol. 168:5551-5557.
-
(2002)
J. Immunol.
, vol.168
, pp. 5551-5557
-
-
Wu, Z.-Q.1
Shen, Y.2
Khan, A.Q.3
Chu, C.-L.4
Riese, R.5
Chapman, H.A.6
Kanagawa, O.7
Snapper, C.M.8
|