CEP-1347 (KT7515), an inhibitor of JNK activation, rescues sympathetic neurons and neuronally differentiated PC12 cells from death evoked by three distinct insults

Journal of Neurochemistry

Volumn 73, Issue 5, 1999, Pages 1901-1912

  Maroney, Anna C ^a   Finn, James P ^a   Bozyczko Coyne, Donna ^a   O'Kane, Teresa M ^a   Neff, Nicola T ^a,d   Tolkovsky, Aviva M ^c   Park, David S ^b,e   Yan, Chao Yun Irene ^b   Troy, Carol M ^b   Greene, Lloyd A ^b  

^a CEPHALON INC   (United States)

^b College of Physicians and Surgeons ^*  (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d DUPONT COMPANY   (United States)

^e UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Apoptosis; C Jun N terminal kinase; CEP 1347; PC12 cells; Sympathetic neurons

Indexed keywords

CEP 1347; COPPER ZINC SUPEROXIDE DISMUTASE; FAS ANTIGEN; K 252A; N ACETYL S NITROSOPENICILLAMINE; NERVE GROWTH FACTOR; PROTEIN KINASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NERVE CELL NECROSIS; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SUPERIOR CERVICAL GANGLION; SYMPATHETIC NERVE CELL; ULTRAVIOLET IRRADIATION;

ANIMALIA; TRIXIS;

EID: 0032692497     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.01901.x     Document Type: Article

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