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Volumn 9, Issue 4, 2005, Pages 243-252

Non-sleep effects of hypocretin/orexin

Author keywords

Aminergic neurotransmitters; Appetite; Autonomic nervous system; Corticotropin releasing factor; Neuroendocrine; Neuropeptide Y; Reproduction; Stress

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; NEUROPEPTIDE Y; NEUROTRANSMITTER; OREXIN;

EID: 22144454312     PISSN: 10870792     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.smrv.2004.07.006     Document Type: Review
Times cited : (60)

References (63)
  • 1
    • 0008390266 scopus 로고    scopus 로고
    • The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity
    • I. De Lecea, T.S. Kilduff, and C. Peyron The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity Proc Natl Acad Sci USA 95 1998 322 327
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 322-327
    • De Lecea, I.1    Kilduff, T.S.2    Peyron, C.3
  • 2
    • 20244380014 scopus 로고    scopus 로고
    • Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
    • T. Sakurai, A. Amemiya, and M. Ishii Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior Cell 92 1998 573 585
    • (1998) Cell , vol.92 , pp. 573-585
    • Sakurai, T.1    Amemiya, A.2    Ishii, M.3
  • 3
    • 0036888981 scopus 로고    scopus 로고
    • Functions of the orexinergic/hypocretinergic system
    • J.P. Kukkonen, T. Holmqvist, and S. Ammoun Functions of the orexinergic/hypocretinergic system Am J Physiol 283 2002 C1567 91
    • (2002) Am J Physiol , vol.283 , pp. 1567-91
    • Kukkonen, J.P.1    Holmqvist, T.2    Ammoun, S.3
  • 4
    • 0142227709 scopus 로고    scopus 로고
    • The orexin/hypocretin system: A critical regulator of neuroendocrine and autonomic function
    • A.V. Ferguson, and W.K. Samson The orexin/hypocretin system: a critical regulator of neuroendocrine and autonomic function Frontiers Neuroendocrinol 24 2003 141 150
    • (2003) Frontiers Neuroendocrinol , vol.24 , pp. 141-150
    • Ferguson, A.V.1    Samson, W.K.2
  • 5
    • 32744460076 scopus 로고    scopus 로고
    • Kilduff in this issue of SMRV.
    • Kilduff in this issue of SMRV.
  • 6
    • 0034992322 scopus 로고    scopus 로고
    • Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity
    • J. Hara, C.T. Beuckmann, and T. Nambu Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity Neuron 30 2001 345 354
    • (2001) Neuron , vol.30 , pp. 345-354
    • Hara, J.1    Beuckmann, C.T.2    Nambu, T.3
  • 7
    • 0041629653 scopus 로고    scopus 로고
    • Attenuated defense response and low basal blood pressure in orexin knockout mice
    • Y. Kayaba, A. Nakamura, and Y. Kasuya Attenuated defense response and low basal blood pressure in orexin knockout mice Am J Physiol 285 2003 R581 93
    • (2003) Am J Physiol , vol.285 , pp. 581-93
    • Kayaba, Y.1    Nakamura, A.2    Kasuya, Y.3
  • 8
    • 0032402181 scopus 로고    scopus 로고
    • Neurons containing hypocretin (orexin) project to multiple neuronal systems
    • C. Peyron, D.K. Tighe, and A.N. van den Pol Neurons containing hypocretin (orexin) project to multiple neuronal systems J Neurosci 18 1998 9996 10015
    • (1998) J Neurosci , vol.18 , pp. 9996-10015
    • Peyron, C.1    Tighe, D.K.2    Van Den Pol, A.N.3
  • 9
    • 0035908286 scopus 로고    scopus 로고
    • Differential expression of orexin receptors 1 and 2 in the rat brain
    • J.N. Marcus, C.J. Aschkenasi, and C.E. Lee Differential expression of orexin receptors 1 and 2 in the rat brain J Comp Neurol 435 2001 6 25
    • (2001) J Comp Neurol , vol.435 , pp. 6-25
    • Marcus, J.N.1    Aschkenasi, C.J.2    Lee, C.E.3
  • 10
    • 0033549237 scopus 로고    scopus 로고
    • Cardiovascular regulatory actions of the hypocretins in brain
    • W.K. Samson, B. Gosnell, and J.K. Chang Cardiovascular regulatory actions of the hypocretins in brain Brain Res 831 1999 248 253
    • (1999) Brain Res , vol.831 , pp. 248-253
    • Samson, W.K.1    Gosnell, B.2    Chang, J.K.3
  • 11
    • 32744468084 scopus 로고    scopus 로고
    • Pressor effects of orexins injected intracisternally and to rostral ventrolateral medulla of anesthetized rats
    • C.T. Chen, L.L. Hwang, and J.K. Chang Pressor effects of orexins injected intracisternally and to rostral ventrolateral medulla of anesthetized rats Am J Physiol 284 2000 R652 4
    • (2000) Am J Physiol , vol.284 , pp. 652-4
    • Chen, C.T.1    Hwang, L.L.2    Chang, J.K.3
  • 12
    • 0033398188 scopus 로고    scopus 로고
    • Sympathetic and cardiovascular actions of orexins in conscious rats
    • T. Shirasaka, M. Nakazato, and S. Matsukura Sympathetic and cardiovascular actions of orexins in conscious rats Am J Physiol 277 1999 R1780 5
    • (1999) Am J Physiol , vol.277 , pp. 1780-5
    • Shirasaka, T.1    Nakazato, M.2    Matsukura, S.3
  • 13
    • 0038206552 scopus 로고    scopus 로고
    • Selective enhancement of synaptic inhibition by hypocretin (orexin) in rat vagal motor neurons: Implications for autonomic regulation
    • S.F. Davis, K.W. Williams, and W. Xu Selective enhancement of synaptic inhibition by hypocretin (orexin) in rat vagal motor neurons: implications for autonomic regulation J Neurosci 23 2003 3844 3854
    • (2003) J Neurosci , vol.23 , pp. 3844-3854
    • Davis, S.F.1    Williams, K.W.2    Xu, W.3
  • 15
    • 0037706224 scopus 로고    scopus 로고
    • Excitatory effects of orexin-A on nucleus tractus solitarius neurons are mediated by phospholipase C and protein kinase C
    • B. Yang, W.K. Samson, and A.V. Ferguson Excitatory effects of orexin-A on nucleus tractus solitarius neurons are mediated by phospholipase C and protein kinase C J Neurosci 23 2003 6215 6222
    • (2003) J Neurosci , vol.23 , pp. 6215-6222
    • Yang, B.1    Samson, W.K.2    Ferguson, A.V.3
  • 16
    • 0037115276 scopus 로고    scopus 로고
    • Cellular mechanisms of orexin actions on paraventricular nucleus neurons in rat hypothalamus
    • M.J. Follwell, and A.V. Ferguson Cellular mechanisms of orexin actions on paraventricular nucleus neurons in rat hypothalamus J Physiol 545 2002 855 867
    • (2002) J Physiol , vol.545 , pp. 855-867
    • Follwell, M.J.1    Ferguson, A.V.2
  • 17
    • 0037144189 scopus 로고    scopus 로고
    • Microinjection of orexin into the rat nucleus tractus solitarius causes increases in blood pressure
    • P.C. Smith, B.C. Connolly, and A.V. Ferguson Microinjection of orexin into the rat nucleus tractus solitarius causes increases in blood pressure Brain Res 950 2002 261 267
    • (2002) Brain Res , vol.950 , pp. 261-267
    • Smith, P.C.1    Connolly, B.C.2    Ferguson, A.V.3
  • 18
    • 0037377565 scopus 로고    scopus 로고
    • Cardiovascular effects of hypocretin-1 in nucleus of the solitary tract
    • C.V.R. de Oliveira, P. Rosas-Arellano, and L. Solano-Flores Cardiovascular effects of hypocretin-1 in nucleus of the solitary tract Am J Physiol 284 2003 H1369 77
    • (2003) Am J Physiol , vol.284 , pp. 1369-77
    • De Oliveira, C.V.R.1    Rosas-Arellano, P.2    Solano-Flores, L.3
  • 19
    • 0037838962 scopus 로고    scopus 로고
    • Cardiac effects of hypocretin-1 in nucleus ambiguus
    • J. Ciriello, and C.V.R. de Oliveira Cardiac effects of hypocretin-1 in nucleus ambiguus Am J Physiol 284 2003 R1611 20
    • (2003) Am J Physiol , vol.284 , pp. 1611-20
    • Ciriello, J.1    De Oliveira, C.V.R.2
  • 20
    • 0038380613 scopus 로고    scopus 로고
    • Orexins induce increased excitability and synchronization of rat sympathetic preganglionic neurons
    • M. van den Top, M.F. Nolan, and K. Lee Orexins induce increased excitability and synchronization of rat sympathetic preganglionic neurons J Physiol 549 2003 809 821
    • (2003) J Physiol , vol.549 , pp. 809-821
    • Van Den Top, M.1    Nolan, M.F.2    Lee, K.3
  • 21
    • 0033552658 scopus 로고    scopus 로고
    • Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system
    • T.L. Horvath, C. Peyron, and S. Diano Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system J Comp Neurol 415 1999 145 159
    • (1999) J Comp Neurol , vol.415 , pp. 145-159
    • Horvath, T.L.1    Peyron, C.2    Diano, S.3
  • 22
    • 0034608355 scopus 로고    scopus 로고
    • Hypocretin/orexin depolarizes and decreases potassium conductance in locus coeruleus neurons
    • A. Ivanov, and G. Aston-Jones Hypocretin/orexin depolarizes and decreases potassium conductance in locus coeruleus neurons Neuroreport 11 2000 1755 1758
    • (2000) Neuroreport , vol.11 , pp. 1755-1758
    • Ivanov, A.1    Aston-Jones, G.2
  • 23
    • 0042316832 scopus 로고    scopus 로고
    • Effects of orexin (hypocretin) on GIRK channels
    • Q.V. Hoang, D. Bajic, and M. Yanagisawa Effects of orexin (hypocretin) on GIRK channels J Neurophysiol 90 2003 693 702
    • (2003) J Neurophysiol , vol.90 , pp. 693-702
    • Hoang, Q.V.1    Bajic, D.2    Yanagisawa, M.3
  • 24
    • 0037095837 scopus 로고    scopus 로고
    • Hypocretin (orexin) enhances neuron activity and cell synchrony in developing mouse GFP-expressing locus coeruleus
    • A.N. van den Pol, P.K. Ghosh, and R. Liu Hypocretin (orexin) enhances neuron activity and cell synchrony in developing mouse GFP-expressing locus coeruleus J Physiol 541 2002 169 185
    • (2002) J Physiol , vol.541 , pp. 169-185
    • Van Den Pol, A.N.1    Ghosh, P.K.2    Liu, R.3
  • 25
    • 0019988336 scopus 로고
    • Autonomic regulation of cardiopulmonary functions in sleep apnea syndrome and narcolepsy
    • C. Sachs, and L. Kaijser Autonomic regulation of cardiopulmonary functions in sleep apnea syndrome and narcolepsy Sleep 5 1982 227 238
    • (1982) Sleep , vol.5 , pp. 227-238
    • Sachs, C.1    Kaijser, L.2
  • 26
    • 0034621042 scopus 로고    scopus 로고
    • Increased body-mass index in patients with narcolepsy
    • A. Schuld, J. Hebebrand, and F. Geller Increased body-mass index in patients with narcolepsy Lancet 355 2000 1274 1275
    • (2000) Lancet , vol.355 , pp. 1274-1275
    • Schuld, A.1    Hebebrand, J.2    Geller, F.3
  • 27
    • 0033588184 scopus 로고    scopus 로고
    • Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation
    • R.M. Chemelli, J.T. Willie, and C.M. Sinton Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation Cell 98 1999 437 451
    • (1999) Cell , vol.98 , pp. 437-451
    • Chemelli, R.M.1    Willie, J.T.2    Sinton, C.M.3
  • 28
    • 0034629016 scopus 로고    scopus 로고
    • Distribution of orexin/hypocretin in the rat median eminence and pituitary
    • Y. Date, M.S. Mondal, and S. Matsukura Distribution of orexin/hypocretin in the rat median eminence and pituitary Brain Res 76 2000 1 6
    • (2000) Brain Res , vol.76 , pp. 1-6
    • Date, Y.1    Mondal, M.S.2    Matsukura, S.3
  • 29
    • 0034799503 scopus 로고    scopus 로고
    • Hypocretin/orexin suppresses corticotroph responsiveness in vitro
    • W.K. Samson, and M.M. Taylor Hypocretin/orexin suppresses corticotroph responsiveness in vitro Am J Physiol 281 2001 R1140 5
    • (2001) Am J Physiol , vol.281 , pp. 1140-5
    • Samson, W.K.1    Taylor, M.M.2
  • 30
    • 0037387349 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone neurons coexpress orexin 1 receptor immunoreactivity and receive direct contacts by orexin fibers
    • R.E. Campbell, K.L. Grove, and M.S. Smith Gonadotropin-releasing hormone neurons coexpress orexin 1 receptor immunoreactivity and receive direct contacts by orexin fibers Endocrinology 144 2003 1542 1549
    • (2003) Endocrinology , vol.144 , pp. 1542-1549
    • Campbell, R.E.1    Grove, K.L.2    Smith, M.S.3
  • 31
    • 0038649174 scopus 로고    scopus 로고
    • Central orexin a has site-specific effects on luteinizing hormone release in female rats
    • C.J. Small, M.L. Goubillon, and J.F. Murray Central orexin A has site-specific effects on luteinizing hormone release in female rats Endocrinology 144 2003 3225 3236
    • (2003) Endocrinology , vol.144 , pp. 3225-3236
    • Small, C.J.1    Goubillon, M.L.2    Murray, J.F.3
  • 32
    • 0037390437 scopus 로고    scopus 로고
    • Gonadal steroids differentially regulate the messenger ribonucleic acid expression of pituitary orexin type 1 receptors and adrenal orexin type 2 receptors
    • O. Joehren, N. Brueggemann, and A. Dendorfer Gonadal steroids differentially regulate the messenger ribonucleic acid expression of pituitary orexin type 1 receptors and adrenal orexin type 2 receptors Endocrinology 144 2003 1219 1225
    • (2003) Endocrinology , vol.144 , pp. 1219-1225
    • Joehren, O.1    Brueggemann, N.2    Dendorfer, A.3
  • 33
    • 13044249865 scopus 로고    scopus 로고
    • Orexin a activates locus coeruleus cell firing and increases arousal in the rat
    • J.J. Hagan, R.A. Leslie, and S. Patel Orexin A activates locus coeruleus cell firing and increases arousal in the rat Proc Natl Acad Sci USA 96 1999 10911 10916
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 10911-10916
    • Hagan, J.J.1    Leslie, R.A.2    Patel, S.3
  • 34
    • 0034595109 scopus 로고    scopus 로고
    • Possible involvement of orexin in the stress reaction in rats
    • T. Ida, N. Nakahara, and T. Murakami Possible involvement of orexin in the stress reaction in rats Biochem Biophys Res Commun 270 2000 318 323
    • (2000) Biochem Biophys Res Commun , vol.270 , pp. 318-323
    • Ida, T.1    Nakahara, N.2    Murakami, T.3
  • 35
    • 0037086828 scopus 로고    scopus 로고
    • Orexin actions in hypothalamic paraventricular nucleus: Physiological consequences and cellular correlates
    • W.K. Samson, M.M. Taylor, and M. Follwell Orexin actions in hypothalamic paraventricular nucleus: physiological consequences and cellular correlates Regul Peptides 104 2002 97 103
    • (2002) Regul Peptides , vol.104 , pp. 97-103
    • Samson, W.K.1    Taylor, M.M.2    Follwell, M.3
  • 36
    • 0033677553 scopus 로고    scopus 로고
    • Effects of orexin on the hypothalamic-pituitary-adrenal system
    • M. Jasberenyi, E. Bujdoso, and I. Pataki Effects of orexin on the hypothalamic-pituitary-adrenal system J Neuroendocrinol 12 2000 1174 1178
    • (2000) J Neuroendocrinol , vol.12 , pp. 1174-1178
    • Jasberenyi, M.1    Bujdoso, E.2    Pataki, I.3
  • 37
    • 0033921449 scopus 로고    scopus 로고
    • Differential distribution and regulation of OX1 and OX2 orexin/hypocretin receptor messenger RNA in the brain upon fasting
    • X.Y. Lu, D. Bagnol, and S. Burke Differential distribution and regulation of OX1 and OX2 orexin/hypocretin receptor messenger RNA in the brain upon fasting Horm Behav 37 2000 335 344
    • (2000) Horm Behav , vol.37 , pp. 335-344
    • Lu, X.Y.1    Bagnol, D.2    Burke, S.3
  • 38
    • 0036041435 scopus 로고    scopus 로고
    • Modulation of hypothalamic hypocrein/orexin mRNA expression by glucocorticoids
    • A. Stricker-Krongard, and B. Beck Modulation of hypothalamic hypocrein/orexin mRNA expression by glucocorticoids Biochem Biophys Res Commun 296 2002 129 133
    • (2002) Biochem Biophys Res Commun , vol.296 , pp. 129-133
    • Stricker-Krongard, A.1    Beck, B.2
  • 39
    • 0022831801 scopus 로고
    • Increased frequency of non-insulin dependent diabetes mellitus among narcoleptic patients
    • Y. Honda, Y. Doi, and R. Nimomiya Increased frequency of non-insulin dependent diabetes mellitus among narcoleptic patients Sleep 9 1986 254 259
    • (1986) Sleep , vol.9 , pp. 254-259
    • Honda, Y.1    Doi, Y.2    Nimomiya, R.3
  • 40
    • 0035402817 scopus 로고    scopus 로고
    • Cellular localization of orexin receptors in human pituitaries
    • M. Blanco, M. Lopez, and T. Garcia-Caballero Cellular localization of orexin receptors in human pituitaries J Clin Endocrinol Metab 86 2001 1616 1619
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1616-1619
    • Blanco, M.1    Lopez, M.2    Garcia-Caballero, T.3
  • 42
    • 0033811876 scopus 로고    scopus 로고
    • Orexin a activates leptin-responsive neurons in the arcuate nucleus
    • M. Rauch, T. Riediger, and H.A. Schmid Orexin A activates leptin-responsive neurons in the arcuate nucleus Pflugers Arch 440 2000 699 703
    • (2000) Pflugers Arch , vol.440 , pp. 699-703
    • Rauch, M.1    Riediger, T.2    Schmid, H.A.3
  • 43
    • 0036161931 scopus 로고    scopus 로고
    • Neuropeptide Y, but not agouti-related peptide or melanin-concentrating hormone, is a target for orexin-A feeding action in the rat hypothalamus
    • M. Lopez, L.M. Seoane, and M.C. Garcia Neuropeptide Y, but not agouti-related peptide or melanin-concentrating hormone, is a target for orexin-A feeding action in the rat hypothalamus Neuroendocrinology 75 2002 34 44
    • (2002) Neuroendocrinology , vol.75 , pp. 34-44
    • Lopez, M.1    Seoane, L.M.2    Garcia, M.C.3
  • 44
    • 0034708393 scopus 로고    scopus 로고
    • Orexin-induced food intake involves neuropeptide Y pathway
    • A. Yamanaka, K. Kunii, and T. Nambu Orexin-induced food intake involves neuropeptide Y pathway Brain Res 859 2000 404 409
    • (2000) Brain Res , vol.859 , pp. 404-409
    • Yamanaka, A.1    Kunii, K.2    Nambu, T.3
  • 45
    • 0035010779 scopus 로고    scopus 로고
    • Neuropeptide Y in central control of feeding and interactions with orexin and leptin
    • M. Niimi, M. Sato, and T. Taminato Neuropeptide Y in central control of feeding and interactions with orexin and leptin Endocrine 14 2001 269 273
    • (2001) Endocrine , vol.14 , pp. 269-273
    • Niimi, M.1    Sato, M.2    Taminato, T.3
  • 46
    • 0034920691 scopus 로고    scopus 로고
    • To eat or to sleep? Orexin in the regulation of feeding and wakefulness
    • J.T. Willie, R.M. Chemelli, and C.M. Sinton To eat or to sleep? Orexin in the regulation of feeding and wakefulness Ann Rev Neurosci 24 2001 429 458
    • (2001) Ann Rev Neurosci , vol.24 , pp. 429-458
    • Willie, J.T.1    Chemelli, R.M.2    Sinton, C.M.3
  • 47
    • 0037775991 scopus 로고    scopus 로고
    • Orexin excites GABAergic neurons of the arcuate nucleus by activating the sodium-calcium exchanger
    • D. Burakov, B. Liss, and F.M. Ashcroft Orexin excites GABAergic neurons of the arcuate nucleus by activating the sodium-calcium exchanger J Neurosci 23 2003 4951 4957
    • (2003) J Neurosci , vol.23 , pp. 4951-4957
    • Burakov, D.1    Liss, B.2    Ashcroft, F.M.3
  • 48
    • 0037388790 scopus 로고    scopus 로고
    • Ghrelin-induced food intake is mediated via the orexin pathway
    • K. Toshinai, Y. Date, and N. Murakami Ghrelin-induced food intake is mediated via the orexin pathway Endocrinology 144 2003 1506 1512
    • (2003) Endocrinology , vol.144 , pp. 1506-1512
    • Toshinai, K.1    Date, Y.2    Murakami, N.3
  • 49
    • 0035576310 scopus 로고    scopus 로고
    • Orexin/hypocretin excites the histaminergic neurons of the tuberomammillary nucleus
    • K.S. Eriksson, A. Sergeeva, and R.E. Brown Orexin/hypocretin excites the histaminergic neurons of the tuberomammillary nucleus J Neurosci 21 2001 9273 9279
    • (2001) J Neurosci , vol.21 , pp. 9273-9279
    • Eriksson, K.S.1    Sergeeva, A.2    Brown, R.E.3
  • 50
    • 0036848635 scopus 로고    scopus 로고
    • Hypocretins (orexins) regulate serotonin neurons in the dorsal raphe nucleus by excitatory direct and indirect actions
    • R.J. Liu, A.N. van den Pol, and G.K. Aghajanian Hypocretins (orexins) regulate serotonin neurons in the dorsal raphe nucleus by excitatory direct and indirect actions J Neurosci 22 2002 9453 9464
    • (2002) J Neurosci , vol.22 , pp. 9453-9464
    • Liu, R.J.1    Van Den Pol, A.N.2    Aghajanian, G.K.3
  • 51
    • 0035800233 scopus 로고    scopus 로고
    • 2+ signaling in dopamine neurons of the ventral tegmental area
    • 2+ signaling in dopamine neurons of the ventral tegmental area Neuroreport 12 2001 1885 1889
    • (2001) Neuroreport , vol.12 , pp. 1885-1889
    • Uramura, K.1    Funahashi, H.2    Muroya, S.3
  • 52
    • 0034714044 scopus 로고    scopus 로고
    • Morphologic evidence for neural interactions between leptin and orexin in the hypothalamus
    • H. Funahashi, T. Hori, and Y. Shimoda Morphologic evidence for neural interactions between leptin and orexin in the hypothalamus Regul Pept 92 2000 31 35
    • (2000) Regul Pept , vol.92 , pp. 31-35
    • Funahashi, H.1    Hori, T.2    Shimoda, Y.3
  • 53
  • 54
    • 1542510707 scopus 로고    scopus 로고
    • Hypothalamus-brainstem circuitry responsible for vagal efferent signaling to the pancreas evoked by hypoglycemia in rat
    • X. Wu, J. Gao, and J. Yan Hypothalamus-brainstem circuitry responsible for vagal efferent signaling to the pancreas evoked by hypoglycemia in rat J Neurophysiol 91 2003 1734 1747
    • (2003) J Neurophysiol , vol.91 , pp. 1734-1747
    • Wu, X.1    Gao, J.2    Yan, J.3
  • 55
    • 0037659189 scopus 로고    scopus 로고
    • Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal
    • D. Georgescu, V. Zachariou, and M. Barot Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal J Neurosci 23 2003 3106 3111
    • (2003) J Neurosci , vol.23 , pp. 3106-3111
    • Georgescu, D.1    Zachariou, V.2    Barot, M.3
  • 56
    • 0036323260 scopus 로고    scopus 로고
    • Eating elicited by orexin-A, but not melanin-concentrating hormone, is opioid mediated
    • D.J. Clegg, E.L. Air, and S.C. Woods Eating elicited by orexin-A, but not melanin-concentrating hormone, is opioid mediated Endocrinology 143 2002 2995 3000
    • (2002) Endocrinology , vol.143 , pp. 2995-3000
    • Clegg, D.J.1    Air, E.L.2    Woods, S.C.3
  • 57
    • 0035055943 scopus 로고    scopus 로고
    • SB-334867, a selective orexin-1 receptor antagonist, enhances behavioral satiety and blocks the hyperphagic effect of orexin-A in rats
    • R.J. Rodgers, J.C. Halford, and R.L. Nunes de Souza SB-334867, a selective orexin-1 receptor antagonist, enhances behavioral satiety and blocks the hyperphagic effect of orexin-A in rats Eur J Neurosci 13 2001 1444 1452
    • (2001) Eur J Neurosci , vol.13 , pp. 1444-1452
    • Rodgers, R.J.1    Halford, J.C.2    Nunes De Souza, R.L.3
  • 58
    • 0344927037 scopus 로고    scopus 로고
    • N-acyl 6.7-dimethoxy-1,2,3,4-tetrahydroisoquinoline: The first orexon-2 receptor selective non-peptidic antagonist
    • M. Hirose, S. Egashira, and Y.N-. Goto N-acyl 6.7-dimethoxy-1,2,3,4- tetrahydroisoquinoline: the first orexon-2 receptor selective non-peptidic antagonist Bioorg Med Chem Lett 13 2003 4497 4499
    • (2003) Bioorg Med Chem Lett , vol.13 , pp. 4497-4499
    • Hirose, M.1    Egashira, S.2    Goto, Y.N.3
  • 59
    • 0034912638 scopus 로고    scopus 로고
    • Prepro-orexin and orexin receptor mRNAs are differentially expressed in peripheral tissues of male and female rats
    • O. Joehren, S.J. Neidert, and M. Kummer Prepro-orexin and orexin receptor mRNAs are differentially expressed in peripheral tissues of male and female rats Endocrinology 142 2001 3324 3331
    • (2001) Endocrinology , vol.142 , pp. 3324-3331
    • Joehren, O.1    Neidert, S.J.2    Kummer, M.3
  • 60
    • 0034750656 scopus 로고    scopus 로고
    • Expression of orexin-A and functional orexin type 2 receptors in the human adult adrenals: Implications for adrenal function and energy homeostasis
    • H.S. Randeva, E. Karteris, and D. Grammatopoulos Expression of orexin-A and functional orexin type 2 receptors in the human adult adrenals: implications for adrenal function and energy homeostasis J Clin Endocrinol Metab 86 2001 4808 4813
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4808-4813
    • Randeva, H.S.1    Karteris, E.2    Grammatopoulos, D.3
  • 61
    • 0035097290 scopus 로고    scopus 로고
    • Orexin stimulates cortisol secretion from human adrenocortical cells through activation of adenylate cyclase-dependent signaling cascade
    • G. Mazzocchi, L.K. Malendowicz, and L. Gottardo Orexin stimulates cortisol secretion from human adrenocortical cells through activation of adenylate cyclase-dependent signaling cascade J Clin Endocrinol Metab 86 2001 778 782
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 778-782
    • Mazzocchi, G.1    Malendowicz, L.K.2    Gottardo, L.3
  • 62
    • 0033305118 scopus 로고    scopus 로고
    • Orexin receptors are expressed in the adrenal medulla of the rat
    • M. Lopez, R. Senaris, and R. Gallego Orexin receptors are expressed in the adrenal medulla of the rat Endocrinology 140 1999 5991 5994
    • (1999) Endocrinology , vol.140 , pp. 5991-5994
    • Lopez, M.1    Senaris, R.2    Gallego, R.3
  • 63
    • 0034748701 scopus 로고    scopus 로고
    • Human pheochromocytomas express orexin receptor type 2 gene and display an in vitro secretory response to orexins a and B
    • G. Mazzocchi, L.K. Malendowicz, and F. Aragona Human pheochromocytomas express orexin receptor type 2 gene and display an in vitro secretory response to orexins A and B J Clin Endocrinol Metabol 86 2001 4818 4821
    • (2001) J Clin Endocrinol Metabol , vol.86 , pp. 4818-4821
    • Mazzocchi, G.1    Malendowicz, L.K.2    Aragona, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.