Hypocretin/orexin depolarizes and decreases potassium conductance in locus coeruleus neurons

NeuroReport

Volumn 11, Issue 8, 2000, Pages 1755-1758

  Ivanov, Alexander ^a   Aston Jones, Gary ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Brain slices; Calcium antagonists; Hypocretin; Neuropeptides; Norepinephrine; Orexin

Indexed keywords

CALCIUM CHANNEL; OREXIN; POTASSIUM; SODIUM CHANNEL; TETRODOTOXIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DEPOLARIZATION; DRUG EFFECT; HYPERPOLARIZATION; LOCUS CERULEUS; MALE; NONHUMAN; NORADRENERGIC NERVE; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; RAT;

EID: 0034608355     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-200006050-00031     Document Type: Article

References (11)

1. 1. de Lecea L, Kilduff TS, Peyron C et al. Proc Natl Acad Sci USA 95, 322-327 (1998).
2. 2. Sakurai T, Amemiya A, Ishii M et al. Cell 92, 573-585 (1998).
3. 3. Peyron C, Tighe DK, van den Pol AN et al. J Neurosci 18, 9996-10015 (1998).
4. 4. Chemelli RM, Willie JT, Sinton CM et al. Cell 98, 437-451 (1999).
5. 5. Lin L, Faraco J, Li R et al. Cell 98, 365-376 (1999).
6. 6. Hagan JJ, Leslie RA, Patel S et al. Proc Natl Acad Sci USA 96, 10911-10916 (1999).
7. 7. Horvath TL, Peyron C, Sabrina D et al. J Camp Neurol 415, 145-159 (1999).
8. 8. Hobson JA, McCarley RW and Wyzinski PW. Science 189, 55-58 (1975).
9. 9. Aston-Jones G and Bloom FE. J Neurosci 1, 876-886 (1981).
10. 10. Aston-Jones G, Rajkowski J and Cohen J. Biol Psychiar 46, 1309-1320 (1999).
11. 11. Ivanov A and Aston-Jones G. J Neurophysiol 74, 2427-2436 (1996).