Central orexin A has site-specific effects on luteinizing hormone release in female rats

Endocrinology

Volumn 144, Issue 7, 2003, Pages 3225-3236

  Small, C J ^b   Goubillon, M L ^c   Murray, J F ^a   Siddiqui, A ^a   Grimshaw, S E ^c   Young, H ^a   Sivanesan, V ^a   Kalamatianos, T ^c   Kennedy, A R ^b   Coen, C W ^c   Bloom, S R ^b   Wilson, C A ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 METHYL 6 BENZOXAZOLYL) 3 (1,5 NAPHTHYRIDIN 4 YL)UREA; ALTHESIN; ESTRADIOL BENZOATE; GONADORELIN; LUTEINIZING HORMONE; OREXIN A; PROGESTERONE; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; BRAIN REGION; CONTROLLED STUDY; CORTICOTROPIN RELEASE; FEMALE; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LUTEINIZING HORMONE RELEASE; MEDIAN EMINENCE; NEUROTRANSMITTER RELEASE; NONHUMAN; ORGANUM VASCULOSUM; OVARIECTOMY; PEPTIDE SYNTHESIS; PREOPTIC AREA; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; TISSUE SPECIFICITY;

ANIMALS; BENZOXAZOLES; CARRIER PROTEINS; CELLS, CULTURED; ESTRADIOL; FEMALE; GONADOTROPIN-RELEASING HORMONE; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUTEINIZING HORMONE; MICROINJECTIONS; NEUROPEPTIDES; OVARIECTOMY; PREOPTIC AREA; PROGESTERONE; RATS; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; UREA;

EID: 0038649174     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2002-0041     Document Type: Article

References (52)

1. Elias CF, Saper CB, Maratos-Flier E, Tritos NA, Lee C, Kelly J, Tatro JB, Hoffman GE, Ollmann MM, Barsh GS, Sakurai T, Yanagisawa M, Elmquist JK 1998 Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area. J Comp Neurol 402:442-459
2. Broberger C, De Lecea L, Sutcliffe JG, Hokfelt T 1998 Hypocretin/orexin- and melanin-concentrating hormone-expressing cells form distinct populations in the rodent lateral hypothalamus: relationship to the neuropeptide Y and agouti gene-related protein systems. J Comp Neurol 402:460-474
3. Kalia V, Fenske C, Hole DR, Wilson CA 1999 Effect of gonadal steroids and γ-aminobutyric acid on LH release and dopamine expression and activity in the zona incerta in rats. J Reprod Fertil 117:189-197
4. McKenzie FJ, James MD, Wilson CA 1988 Changes in dopamine activity in the zona incerta (ZI) over the rat oestrious cycle and the effect of lesions of the ZI on cyclicity: further evidence that the incerto-hypothalamic tract has a stimulatory role in the control of LH release. Brain Res 444:75-83
5. Gonzalez MI, Baker BI, Wilson CA 1997 Stimulatory effect of melanin concentrating hormone on LH release. Neuroendocrinology 66:254-262
6. Pu S, Jain MR, Kalra PS, Kalra SP 1998 Orexins, a novel family of hypothalamic neuropeptides, modulate pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner. Regul Pept 78:133-136
7. Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Clay Williams S, Richardson JA, Kozlowski GP, Wilson S, Arch JRS, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu W-S, Terrett JA, Elshourbagy NA, Bergsma DJ, Yanagisawa M 1998 Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behaviour. Cell 92:573-585
8. Edwards CMB, Abusnana S, Sunter D, Murphy KG, Ghatei MA, Bloom SR 1999 The effect of the orexins on food intake: comparison with neuropeptide Y, melanin-concentrating hormone and galanin. J Endocrinol 160:R7-R12
9. Trivedi P, Yu H, MacNeil DJ, Van der Ploeg LHT, Guan X-M 1998 Distribution of orexin receptor mRNA in the rat brain. FEBS Lett 438:71-75
10. Marcus JN, Aschkenasi CJ, Lee CE, Chemelli RM, Saper CB, Yanagisawa M, Elmquist JK 2001 Differential expression of orexin receptors 1 and 2 in the rat brain. J Comp Neurol 435:6-25
11. Horvath TL, Diano S, van den Pol AN 1999 Synaptic interaction between hypocretin (orexin) and neuropeptide Y ceils in the rodent and primate hypothalamus: a novel circuit implicated in metabolic and endocrine regulations. J Neurosci 19:1072-1087
12. De Lecea L, Kilduff TS, Peyron C, Gao X-B, Foye PE, Danielson PE, Fukuhara C, Battenberg ELF, Gautvik VT, Bartlett II FS, Frankel WN, van den Pol AN, Bloom FE, Gautvik KM, Sutcliffe JG 1998 The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc Natl Acad Sci USA 95: 322-327
13. Hagan JJ, Leslie RA, Patel S, Evans ML, Wattam TA, Holmes S, Benham CD, Taylor SG, Routledge C, Hemmati P, Munton RP, Ashmeade TE, Shah AS, Hatcher JP, Hatcher PD, Jones DNC, Smith MI, Piper DC, Hunter AJ, Porter RA, Upton N 1999 Orexin A activates locus coeruleus cell firing and increases arousal in the rat. Proc Natl Acad Sci USA 96:10911-10916
14. Piper DC, Upton N, Smith MI, Hunter AJ 2000 The novel brain neuropeptide, orexin-A, modulates the sleep-wake cycle of rats. Eur J Neurosci 12:726-730
15. Blanco M, López M, Garcia-Caballero T, Gallego R, Váquez-Boquete A, Morel G, Senaris R, Casanueva F, Diéguez C, Beiras A 2001 Cellular localization of orexin receptors in human pituitary. J Clin Endocrinol Metab 86: 1616-1619
16. Al-Barazanji KA, Wilson S, Baker J, Jessop DS, Harbuz MS 2001 Central orexin-A activates hypothalamic-pituitary-adrenal axis and stimulates hypothalamie corticotropin releasing factor and arginine vasopressin neurones in conscious rats. J Neuroendocrinol 13:421-424
17. Kohsaka A, Watanobe H, Kakizaki Y, Suda T, Schiöth HB 2001 A significant participation of orexin-A, a potent orexigenic peptide, in the preovulatory luteinizing hormone and prolactin surges in the rat. Brain Res 898:166-170
18. Tamura T, Irahara M, Tezuka M, Kiyokawa M, Aono T 1999 Orexins, orexigenic hypothalamic neuropeptides, suppress the pulsatile secretion of luteinizing hormone in ovariectomized female rats. Biochem Biophys Res Commun 264:759-762
19. Furuta M, Funabashi T, Kimura F 2002 Suppressive action of orexin A on pulsatile luteinizing hormone secretion is potentiated by a low dose of oestrogen in ovariectomised rats. Neuroendocrinology 75:151-157
20. Russell SH, Small CJ, Kennedy AR, Stanley SA, Seth A, Murphy KG, Taheri S, Ghatei MA, Bloom SR 2001 Orexin A interactions in the hypothalamopituitary gonadal axis. Endocrinology 142:5294-5302
21. Iqbal J, Pompolo S, Sakurai T, Clarke IJ 2001 Evidence that orexin-containing neurones provide direct input to gonadotrophin-releasing hormone neurones in the ovine hypothalamus. J Neuroendocrinol 13:1033-1041
22. Gorski RA, Gordon JH, Shryne JE, Southam AM 1978 Evidence for a morphological sex difference within the medial preoptic area of the rat brain. Brain Res 148:333-346
23. Goodman RL 1978 The site of the positive feedback action of estradiol in the rat. Endocrinology 102:151-159
24. Witkin JW, Paden CM, Silverman AJ 1982 The Luteinizing-hormone-releasing-hormone (LHRH) systems in the rat brain. Neuroendocrinology 35: 429-438
25. Siddiqui A, Kotecha K, Salicioni A-M, Kalia V, Murray JF, Wilson CA 2000 Serotonin inhibits luteinizing hormone release via 5-HT1A receptors in the zona incerta of ovariectomised, anaesthetised rats primed with steroids. Neuroendocrinology 72:272-283
26. Paxinos G, Watson C 1998 The rat brain in stereotaxic coordinates. 4th ed. New York: Academic Press
27. Smart D, Sabido-David C, Brough SJ, Jewitt F, Johns A, Porter RA, Jerman JC 2001 SB-334867-A: the first selective orexin-1 receptor antagonist. Br J Pharmacol 132:1179-1182
28. Haynes AC, Jackson B, Chapman H, Tadayyon M, Johns A, Porter RA, Arch JRS 2000 A selective orexin-1 receptor antagonist reduces food consumption in male and female rats. Regul Pept 96:45-51
29. Gonzalez MI, Vaziri S, Wilson CA 1996 Behavioural effects of α-MSH and MCH after central administration in the female rat. Peptides 17:171-177
30. Goubillon M-L, Strutton PH, O'Byrne KT, Thalabard J-C, Coen CW 1999 Ketamine-induced general anaesthesia is compatible with gonadotrophin-releasing hormone pulse generator activity in gonadectomised rats: prospects for detailed electrophysiological studies in vivo. Brain Res 841:197-201
31. van Cauter E 1981 Quantitative methods for analysis of circadian and episodic hormone fluctuation. In: van Carter E, Copinschi G, eds. Human pituitary hormone: circadian, episodic variations. The Hague: Martinus Nyhoff; 1-25
32. Beak SA, Heath MM, Small CJ, Morgan DG, Ghatei MA, Taylor AD, Buckingham JC, Bloom SR, Smith DM 1998 Glucagon-like peptide-1 stimulates luteinizing hormone-releasing hormone secretion in a rodent hypothalamic neuronal cell line. J Clin Invest 101:1334-1341
33. Matthews JNS, Altman DG, Campbell MJ, Royston P 1990 Analysis of serial measurements in medical research. BMJ 300:230-235
34. Kalra SP 1993 Mandatory neuropeptide-steroid signalling for the pre-ovulatory luteinizing hormone releasing hormone discharge. Endocr Rev 14:507-536
35. Kitts CS, Johnson JH 1986 Reversal by estrogen of the effect of dorsal raphe stimulation on release of LH but not prolactin. J Neurosci Res 15:253-259
36. Herbison AE, Heavans SP, Dyer RG 1990 Oestrogen modulation of excitatory A1 noradrenergie input to the rat medial preoptic γ-aminobutyric acid neurones demonstration by microdialysis. Neuroendoerinology 52:161-168
37. Kalra PA, Norlin M, Kalra SP 1995 Neuropeptide Y stimulates β-endorphin release in the basal hypothalamus: role of gonadal steroids. Brain Res 705: 353-356
38. Herbison AE 1997 Noradrenergic regulation of cyclic GnRH secretion. Rev Reprod 2:1-6
39. Fuxe K, Hokfelt T, Ungerstedt U 1969 Distribution of monoamines in the mammalian central nervous system by histochemical studies. In: Hooper G, ed. Metabolism of amines in the brain. London: MacMillan; 10-22
40. Fuxe K, Lofstrom A, Eneroth P, Gustafsson J-A, Skett P, Hokfelt T, Weisel EA, Agnati L 1977 Involvement of central catecholamines in the feedback actions of 17-β-oestradiol benzoate on luteinizing hormone secretions in the ovariectomised female rat. Psychoneuroendocrinology 2:203-225
41. McKenzie FJ, Hunter AJ, Daly C, Wilson CA 1984 Evidence that the dopaminergic incerto-hypothalamic tract has a stimulatory effect on ovulation and gonadotrophin release. Neuroendocrinology 39:289-295
42. Sanghera MK, Anselmo-Franci J, McCann SM 1991 Effect of medial zona incerta lesions on the ovulatory surge of gonadotrophins and prolactin in the rat. Neuroendocrinology 54:433-438
43. Morello H, Caligaris L, Haymal B, Taleisnik S 1990 Further evidence of an opposite effect of dorsal and median raphe nuclei on the proestrous surge of LH. Acta Endocrinol. 122:676-702
44. Morello H, Taleisnik S 1985 Changes in the release of luteinizing hormone on the day of proestrus after lesions or stimulation of the raphe nuclei in rats. Brain Res 360:311-317
45. Vitale ML, Villar MJ, Chiochio SR, Tramezzani JA 1987 Dorsal raphe lesion alters the estrous cycle and the preovulatory gonadotrophin release. Neuroendocrinology 46:252-257
46. Backberg M, Hervieu G, Wilson S, Meister B 2002 Orexin receptor-1 (Ox-Ri) immunoreactivity in chemically identified neurons of the hypothalamus: focus on orexin targets involved in control of food and water intake. Eur J Neurosci 15:315-328
47. van den Pol AN, Gao X-B, Obrietan K, Kilduff TS, Belousoy AB 1998 Presynaptic and postsynaptic actions and modulation of neuroendocrine neurons by a new hypothalamic peptide, hypocretin/orexin. J Neurosci 18:7962-7971
48. Jászberényi M, Bujdoso E, Telegdy G 2001 The role of neuropeptide Y in orexin-induced hypothalamic-pituitary-adrenal activation. J Neuroendocrinol 13:438-441
49. Hsueh YC, Cheng SM, Pan JT 2002 Fasting stimulates tuberoinfundibular dopaminergic neuronal activity and it inhibits prolactin secretion in oestrogen-primed ovariectomised rats: involvement of orexin A and neuropeptide Y. J Neuroendocrinol 14:745-752
50. 2C receptor involvement. Psychopharmacology 153: 203-209
51. Irahara M, Tamura T, Matuzaki T, Saito S, Yasui T, Yamano S, Kamada M, Aono T 2001 Orexin-A suppresses the pulsatile secretion of luteinizing hormone via β-endorphin. Biochem Biophys Res Commun 281:232-236
52. Swanson LW 1992 Brain maps: structure of the rat brain. Amsterdam: Elsevier