-
1
-
-
0037169354
-
Cancer susceptibility and the functions of BRCA1 and BRCA2
-
Venkitaraman, A.R. Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell 108, 171-182 (2002).
-
(2002)
Cell
, vol.108
, pp. 171-182
-
-
Venkitaraman, A.R.1
-
2
-
-
0034707053
-
In search of the tumour-suppressor functions of BRCA1 and BRCA2
-
Scully, R. & Livingston, D.M. In search of the tumour-suppressor functions of BRCA1 and BRCA2. Nature 408, 429-432 (2000).
-
(2000)
Nature
, vol.408
, pp. 429-432
-
-
Scully, R.1
Livingston, D.M.2
-
3
-
-
0035928799
-
New complexities for BRCA1 and BRCA2
-
Kerr, P. & Ashworth, A. New complexities for BRCA1 and BRCA2. Curr. Biol. 11, R668-R676 (2001).
-
(2001)
Curr. Biol.
, vol.11
-
-
Kerr, P.1
Ashworth, A.2
-
4
-
-
0035479017
-
BRCA1-associated tumorigenesis: What have we learned from knockout mice?
-
Brodie, S.G. & Deng, C.X. BRCA1-associated tumorigenesis: what have we learned from knockout mice? Trends Genet. 17, S18-S22 (2001).
-
(2001)
Trends Genet.
, vol.17
-
-
Brodie, S.G.1
Deng, C.X.2
-
5
-
-
0034946638
-
Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis
-
Xu, X. et al. Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis. Nat. Genet. 28, 266-271 (2001).
-
(2001)
Nat. Genet.
, vol.28
, pp. 266-271
-
-
Xu, X.1
-
6
-
-
0032587877
-
Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation
-
Xu, X. et al. Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation. Nat. Genet. 22, 37-43 (1999).
-
(1999)
Nat. Genet.
, vol.22
, pp. 37-43
-
-
Xu, X.1
-
7
-
-
0030850047
-
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
-
Scully, R. et al. Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell 90, 425-435 (1997).
-
(1997)
Cell
, vol.90
, pp. 425-435
-
-
Scully, R.1
-
8
-
-
0031472370
-
Association of BRCA1 with Rad51 in mitotic and meiotic cells
-
Scully R. et al. Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell 88, 265-275 (1997).
-
(1997)
Cell
, vol.88
, pp. 265-275
-
-
Scully, R.1
-
9
-
-
2342564452
-
Human topoisomerase IIalpha: Targeting to subchromosomal sites of activity during interphase and mitosis
-
Agostinho, M. et al. Human topoisomerase IIalpha: targeting to subchromosomal sites of activity during interphase and mitosis. Mol. Biol. Cell 15, 2388-2400 (2004).
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 2388-2400
-
-
Agostinho, M.1
-
10
-
-
0034988263
-
Co-localization of chicken DNA topoisomerase IIalpha, but not beta, with sites of DNA replication and possible involvement of a C-terminal region of alpha through its binding to PCNA
-
Niimi, A., Suka, N., Harata, M., Kikuchi, A. & Mizuno, S. Co-localization of chicken DNA topoisomerase IIalpha, but not beta, with sites of DNA replication and possible involvement of a C-terminal region of alpha through its binding to PCNA. Chromosome 110, 102-114 (2001).
-
(2001)
Chromosome
, vol.110
, pp. 102-114
-
-
Niimi, A.1
Suka, N.2
Harata, M.3
Kikuchi, A.4
Mizuno, S.5
-
11
-
-
0142147272
-
The BRCT domain is a phospho-protein binding domain
-
Yu, X., Chini, C.C., He, M., Mer, G. & Chen, J. The BRCT domain is a phospho-protein binding domain. Science 301, 639-642 (2003).
-
(2003)
Science
, vol.301
, pp. 639-642
-
-
Yu, X.1
Chini, C.C.2
He, M.3
Mer, G.4
Chen, J.5
-
12
-
-
0142240342
-
BRCT repeats as phosphopeptide-binding modules involved in protein targeting
-
Manke, I.A., Lowery, D.M., Nguyen, A. & Yaffe, M.B. BRCT repeats as phosphopeptide-binding modules involved in protein targeting. Science 302, 636-639 (2003).
-
(2003)
Science
, vol.302
, pp. 636-639
-
-
Manke, I.A.1
Lowery, D.M.2
Nguyen, A.3
Yaffe, M.B.4
-
13
-
-
0030014783
-
DNA topoisomerases
-
Wang, J.C. DNA topoisomerases. Annu. Rev. Biochem. 65, 635-692 (1996).
-
(1996)
Annu. Rev. Biochem.
, vol.65
, pp. 635-692
-
-
Wang, J.C.1
-
14
-
-
0026425654
-
Inhibition of intracellular topoisomerase II by antitumor bis(2,6-dioxopiperazine) derivatives: Mode of cell growth inhibition distinct from that of cleavable complex-forming type inhibitors
-
Ishida, R. et al. Inhibition of intracellular topoisomerase II by antitumor bis(2,6-dioxopiperazine) derivatives: mode of cell growth inhibition distinct from that of cleavable complex-forming type inhibitors. Cancer Res. 51, 4909-4916 (1991).
-
(1991)
Cancer Res.
, vol.51
, pp. 4909-4916
-
-
Ishida, R.1
-
15
-
-
0027209306
-
Topoisomerase II inhibition prevents anaphase chromatid segregation in mammalian cells independently of the generation of DNA strand breaks
-
Clarke, D.J., Johnson, R.T. & Downes, C.S. Topoisomerase II inhibition prevents anaphase chromatid segregation in mammalian cells independently of the generation of DNA strand breaks. J. Cell Sci. 105, 563-569 (1993).
-
(1993)
J. Cell Sci.
, vol.105
, pp. 563-569
-
-
Clarke, D.J.1
Johnson, R.T.2
Downes, C.S.3
-
16
-
-
0036510163
-
BRCA1l regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage
-
Yarden, R.I., Pardo-Reoyo, S., Sgagias, M., Cowan, K.H. & Brody, L.C. BRCA1l regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage. Nat. Genet. 30, 285-289 (2002).
-
(2002)
Nat. Genet.
, vol.30
, pp. 285-289
-
-
Yarden, R.I.1
Pardo-Reoyo, S.2
Sgagias, M.3
Cowan, K.H.4
Brody, L.C.5
-
17
-
-
0035890272
-
Topoisomerase II can unlink replicating DNA by precatenane removal
-
Lucas, I., Germe, T., Chevrier-Miller, M. & Hyrien, O. Topoisomerase II can unlink replicating DNA by precatenane removal. EMBO J. 20, 6509-6519 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 6509-6519
-
-
Lucas, I.1
Germe, T.2
Chevrier-Miller, M.3
Hyrien, O.4
-
18
-
-
0019321213
-
Decatenation of kinetoplast DNA by topoisomerases
-
Marini, J.C. Miller, K.G. & Englund, P.T. Decatenation of kinetoplast DNA by topoisomerases. J. Biol. Chem. 255, 4976-4979 (1980).
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 4976-4979
-
-
Marini, J.C.1
Miller, K.G.2
Englund, P.T.3
-
19
-
-
0029102757
-
Resolving the role of topoisomerase II in chromatin structure and function
-
Poljak, L. & Kas, E. Resolving the role of topoisomerase II in chromatin structure and function. Trends Cell Biol. 5, 348-354 (1995).
-
(1995)
Trends Cell Biol.
, vol.5
, pp. 348-354
-
-
Poljak, L.1
Kas, E.2
-
20
-
-
0027165514
-
DNA topoisomerase IIl alpha is the major chromosome protein recognized by the mitotic phosphoprotein antibody MPM-2
-
Taagepera, S., Rao, P.N., Drake, F.H. & Gorbsky, G.J. DNA topoisomerase IIl alpha is the major chromosome protein recognized by the mitotic phosphoprotein antibody MPM-2. Proc. Natl Acad. Sci. USA 90, 8407-8411 (1993).
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 8407-8411
-
-
Taagepera, S.1
Rao, P.N.2
Drake, F.H.3
Gorbsky, G.J.4
-
21
-
-
0036467574
-
The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity
-
Baer, R. & Ludwig, T. The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity. Curr. Opin. Genet. Dev. 12, 86-91 (2002).
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 86-91
-
-
Baer, R.1
Ludwig, T.2
-
22
-
-
0037684805
-
The multiple nuclear functions of BRCA1: Transcription, ubiquitination and DNA repair
-
Starita, L.M. & Parvin, J.D. The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair. Curr. Opin. Cell Biol. 15, 345-350 (2003).
-
(2003)
Curr. Opin. Cell Biol.
, vol.15
, pp. 345-350
-
-
Starita, L.M.1
Parvin, J.D.2
-
23
-
-
0035313393
-
Role of proteasomal degradation in the cell cycle-dependent regulation of DNA topoisomerase IIalpha expression
-
Salmena, L., Lam, V., McPherson, J.P & Goldenberg, G.J. Role of proteasomal degradation in the cell cycle-dependent regulation of DNA topoisomerase IIalpha expression. Biochem. Pharmacol. 61, 795-802 (2001).
-
(2001)
Biochem. Pharmacol.
, vol.61
, pp. 795-802
-
-
Salmena, L.1
Lam, V.2
McPherson, J.P.3
Goldenberg, G.J.4
-
24
-
-
0036291014
-
The SUMO-1 isopeptidase Smt4 is linked to centromeric cohesion through SUMO-1 modification of DNA topoisomerase II
-
Bachant, J., Alcasabas, A., Blat, Y., Kleckner, N. & Elledge, S.J. The SUMO-1 isopeptidase Smt4 is linked to centromeric cohesion through SUMO-1 modification of DNA topoisomerase II. Mol. Cell 9, 1169-1182 (2002).
-
(2002)
Mol. Cell
, vol.9
, pp. 1169-1182
-
-
Bachant, J.1
Alcasabas, A.2
Blat, Y.3
Kleckner, N.4
Elledge, S.J.5
-
25
-
-
0242509262
-
SUMO-2/3 regulates topoisomerase II in mitosis
-
Azuma, Y., Arnaoutov, A. & Dasso, M. SUMO-2/3 regulates topoisomerase II in mitosis. J. Cell Biol. 163, 477-487 (2003).
-
(2003)
J. Cell Biol.
, vol.163
, pp. 477-487
-
-
Azuma, Y.1
Arnaoutov, A.2
Dasso, M.3
-
26
-
-
0031018820
-
Cell cycle-coupled relocation of types I and II topoisomerases and modulation of catalytic enzyme activities
-
Meyer, K.N. et al. Cell cycle-coupled relocation of types I and II topoisomerases and modulation of catalytic enzyme activities. J. Cell Biol. 136, 775-788 (1997).
-
(1997)
J. Cell Biol.
, vol.136
, pp. 775-788
-
-
Meyer, K.N.1
-
27
-
-
10344230981
-
A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint
-
Wang, R.H., Yu, H. & Deng, C.X. A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint. Proc. Natl Acad. Sci. USA 101, 17108-17113 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 17108-17113
-
-
Wang, R.H.1
Yu, H.2
Deng, C.X.3
-
28
-
-
0343526732
-
Premitotic chromosome individualization in mammalian cells depends on topoisomerase II activity
-
Gimenez-Abian, J.F. et al. Premitotic chromosome individualization in mammalian cells depends on topoisomerase II activity. Chromosoms 109, 235-244 (2000).
-
(2000)
Chromosoms
, vol.109
, pp. 235-244
-
-
Gimenez-Abian, J.F.1
-
29
-
-
0035834003
-
The human decatenation checkpoint
-
Deming, P.B. et al. The human decatenation checkpoint. Proc. Natl Acad. Sci. USA 98, 12044-12049 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 12044-12049
-
-
Deming, P.B.1
-
30
-
-
0030570004
-
Location of BRCA1 in human breast and ovarian cancer cells
-
Scully, R. et al. Location of BRCA1 in human breast and ovarian cancer cells. Science 212, 123-126 (1996).
-
(1996)
Science
, vol.212
, pp. 123-126
-
-
Scully, R.1
-
31
-
-
0033119506
-
BRCA1, BRCA2, and Rad51 operate in a common DNA damage response pathway
-
Chen, J.J., Silver, D., Cantor, S., Livingston, D.M. & Scully, R. BRCA1, BRCA2, and Rad51 operate in a common DNA damage response pathway. Cancer Res. 59, 1752s-1756s (1999).
-
(1999)
Cancer Res.
, vol.59
-
-
Chen, J.J.1
Silver, D.2
Cantor, S.3
Livingston, D.M.4
Scully, R.5
-
32
-
-
0035972194
-
Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways
-
Rappold, I., Iwabuchi, K., Date, T. & Chen, J. Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways. J. Cell Biol. 153, 613-620 (2001).
-
(2001)
J. Cell Biol.
, vol.153
, pp. 613-620
-
-
Rappold, I.1
Iwabuchi, K.2
Date, T.3
Chen, J.4
-
33
-
-
0037468232
-
MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways
-
Lou, Z., Minter-Dykhouse, K., Wu, X. & Chen, J, MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways. Nature 421, 957-961 (2003).
-
(2003)
Nature
, vol.421
, pp. 957-961
-
-
Lou, Z.1
Minter-Dykhouse, K.2
Wu, X.3
Chen, J.4
-
34
-
-
0038496703
-
Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control
-
Lou, Z., Chini, C.C., Minter-Dykhouse, K. & Chen, J. Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control. J. Biol. Chem. 278, 13599-13602 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 13599-13602
-
-
Lou, Z.1
Chini, C.C.2
Minter-Dykhouse, K.3
Chen, J.4
|