Topoisomerase II can unlink replicating DNA by precatenane removal

EMBO Journal

Volumn 20, Issue 22, 2001, Pages 6509-6519

  Lucas, Isabelle ^a   Germe, Thomas ^b   Chevrier Miller, Marianne ^b   Hyrien, Olivier ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b ECOLE NORMALE SUPÉRIEURE   (France)

Author keywords

DNA replication; DNA topoisomerases; Nuclear assembly; Topoisomerase inhibitors; Xenopus

Indexed keywords

CATENANE; DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); ETOPOSIDE;

ANIMAL CELL; ARTICLE; CELL CYCLE S PHASE; CHROMATIN STRUCTURE; CONTROLLED STUDY; DNA REPLICATION; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME SUBUNIT; MITOSIS; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN ASSEMBLY; TWO DIMENSIONAL GEL ELECTROPHORESIS; XENOPUS;

ANIMALS; CELL NUCLEUS; CHROMATIN; DNA; DNA REPLICATION; DNA TOPOISOMERASES, TYPE II; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ETOPOSIDE; MITOSIS; MODELS, BIOLOGICAL; NUCLEIC ACID SYNTHESIS INHIBITORS; OVUM; PLASMIDS; S PHASE; SISTER CHROMATID EXCHANGE; TIME FACTORS; XENOPUS;

AMPHIBIA; ANIMALIA; EUKARYOTA; REPTILIA;

EID: 0035890272     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.22.6509     Document Type: Article

References (61)

1. Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks
2. Topoisomerase II drives DNA transport by hydrolyzing one ATP
3. Two-dimensional gel analysis of rolling circle replication in the presence and absence of bacteriophage T4 primase
4. Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs
5. Replication of purified DNA in Xenopus egg extract is dependent on nuclear assembly
6. The localization of replication origins on ARS plasmids in S.cerevisiae
7. Analysis of replication intermediates by two-dimensional agarose gel electrophoresis
8. Need for DNA topoisomerase activity as a swivel for DNA replication for transcription of ribosomal RNA
9. Topoisomerases and the swivel problem
10. Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II
11. DNA replication in cell-free extracts from Xenopus eggs is prevented by disrupting nuclear envelope function
12. DNA replication occurs at discrete sites in pseudonuclei assembled from purified DNA in vitro
13. Preferential relaxation of positively supercoiled DNA by E.coli topoisomerase IV in single-molecule and ensemble measurements
14. Anaphase chromatid motion: Involvement of type II DNA topoisomerases
15. Inhibition of in vitro nuclear transport by a lectin that binds to nuclear pores
16. Topoisomerase II as a target for anticancer drugs: When enzymes stop being nice
17. The stability of nucleosomes at the replication fork
18. Polyoma virus minichromosomes: Characterization of the products of in vitro DNA synthesis
19. Topoisomerase III, but not topoisomerase I, can support nascent chain elongation during θ-type DNA replication
20. Two distinct modes of strand unlinking during θ-type DNA replication
21. Coming undone: How to untangle a chromosome
22. DNA topoisomerase II is required at the time of mitosis in yeast
23. An antitumor drug-induced topoisomerase cleavage complex blocks a bacteriophage T4 replication fork in vivo
24. Plasmid replication in Xenopus eggs and egg extracts: A 2D gel electrophoretic analysis
25. Chromosomal replication initiates and terminates at random sequences but at regular intervals in the ribosomal DNA of Xenopus early embryos
26. Role of nuclear architecture in the initiation of eukaryotic DNA replication
27. Effect of ICRF-193, a novel DNA topoisomerase II inhibitor, on simian virus 40 DNA and chromosome replication in vitro
28. Topoisomerase II plays an essential role as a swivelase in the late stage of SV40 chromosome replication in vitro
29. Synthesis of simian virus 40 C-family catenated dimers in vivo in the presence of ICRF-193
30. Function of DNA topoisomerases as replication swivels in Saccharomyces cerevisiae
31. Catenation of DNA rings by topoisomerases. Mechanism of control by spermidine
32. DNA gyrase and topoisomerase IV: Biochemical activities, physiological roles during chromosome replication and drug sensitivities
33. Mechanisms ensuring rapid and complete DNA replication despite random initiation in Xenopus early embryos
34. DNA replication initiates at multiple sites on plasmid DNA in Xenopus egg extracts
35. SUMO-1 conjugation to human DNA topoisomerase II isozymes
36. SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerasemediated DNA damage
37. Initiation of DNA replication in CoE plasmids containing multiple potential origins of replication
38. Topological complexity of different populations of pBR322 as visualized by two-dimensional agarose gel electrophoresis
39. Nuclear reconstitution in vitro: Stages of assembly around protein-free DNA
40. Decatenation activity of topoisomerase IV during oriC and pBR322 DNA replication in vitro
41. Inverse relationship between catenation and superhelicity in newly replicated simian virus 40 daughter chromosomes
42. The structure of supercoiled intermediates in DNA replication
43. Positive torsional strain causes the formation of a four-way junction at replication forks
44. Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes
45. Effects of VM26 (teniposide), a specific inhibitor of type VI DNA topoisomerase, on SV40 DNA replication in vivo
46. Simplification of DNA topology below equilibrium values by type II topoisomerases
47. The effect of ionic conditions on the conformations of supercoiled DNA. II. Equilibrium catenation
48. Sister chromatid separation in frog egg extracts requires DNA topoisomerase II activity during anaphase
49. Topoisomerase inhibitors can selectively interfere with different stages of simian virus 40 DNA replication
50. Formation of knots in partially replicated DNA molecules
51. Vaccinia DNA topoisomerase I: Evidence supporting a free rotation mechanism for DNA supercoil relaxation
52. Single-molecule analysis of DNA uncoiling by a type II topoisomerase
53. Arrest of segregation leads to accumulation of highly intertwined catenated dimers: Dissection of the final stages of SV40 DNA replication
54. ICRF-193, an inhibitor of topoisomerase II, demonstrates that DNA replication in sperm nuclei reconstituted in Xenopus egg extracts does not require chromatin decondensation
55. Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives
56. Mitotic spindle pulls but fails to separate chromosomes in type II DNA topoisomerase mutants: Uncoordinated mitosis
57. Unlinking of DNA by topoisomerases during DNA replication
58. Regulated chromosomal DNA replication in the absence of a nucleus
59. Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro
60. Roles of topoisomerase IV and DNA gyrase in DNA unlinking during replication in Escherichiacoli