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Volumn 31, Issue 3, 2005, Pages 266-271

MTHFR C677T polymorphism and factor V Leiden mutation are not associated with recurrent spontaneous abortion of unexplained etiology in Japanese women

Author keywords

Factor V; Gene; MTHFR; Polymorphism; Recurrent spontaneous abortion

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); BLOOD CLOTTING FACTOR 5 LEIDEN;

EID: 21844458934     PISSN: 00946176     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-872430     Document Type: Article
Times cited : (30)

References (46)
  • 1
    • 0032746068 scopus 로고    scopus 로고
    • Thrombophilia-associated pregnancy wastage
    • Blumenfeld Z, Brenner B. Thrombophilia-associated pregnancy wastage. Fertil Steril 1999;72:765-774
    • (1999) Fertil Steril , vol.72 , pp. 765-774
    • Blumenfeld, Z.1    Brenner, B.2
  • 2
    • 0028034263 scopus 로고
    • Recurrent miscarriage
    • Katz V, Kuller J. Recurrent miscarriage. Am J Perinatol 1994; 11:386-397
    • (1994) Am J Perinatol , vol.11 , pp. 386-397
    • Katz, V.1    Kuller, J.2
  • 3
    • 16044369784 scopus 로고    scopus 로고
    • Increased fetal loss in women with heritable thrombophilia
    • Preston FE, Rosendaal FR, Walker ID, et al. Increased fetal loss in women with heritable thrombophilia. Lancet 1996; 348:913-916
    • (1996) Lancet , vol.348 , pp. 913-916
    • Preston, F.E.1    Rosendaal, F.R.2    Walker, I.D.3
  • 4
    • 0030610090 scopus 로고    scopus 로고
    • The mutation Ala677-Val in the methylenetetrahydrofolate reductase gene: A risk factor for arterial disease and venous thrombosis
    • Arruda VR, Von zuben PM, Ciapurini LC, Annichino-Bizzachi JM, Costa FF. The mutation Ala677-Val in the methylenetetrahydrofolate reductase gene: a risk factor for arterial disease and venous thrombosis. Thromb Haemost 1997;77:818-821
    • (1997) Thromb Haemost , vol.77 , pp. 818-821
    • Arruda, V.R.1    Von Zuben, P.M.2    Ciapurini, L.C.3    Annichino-Bizzachi, J.M.4    Costa, F.F.5
  • 5
    • 0028314865 scopus 로고
    • Mutation in the blood coagulation factor V associated with resistance to activated protein C
    • Bertina RM, Koclaman BP, Koster T, et al. Mutation in the blood coagulation factor V associated with resistance to activated protein C. Nature 1994;369:64-67
    • (1994) Nature , vol.369 , pp. 64-67
    • Bertina, R.M.1    Koclaman, B.P.2    Koster, T.3
  • 6
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
    • Frosst P, Blom HJ, Milos R. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 1995;10:111-113
    • (1995) Nat Genet , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3
  • 7
    • 0023696435 scopus 로고
    • Intermediate homocysteinemia: A thermolabile variant of methylenetetrahydrofolate reductase
    • Kang SS, Zhou J, Wong PW, Kowalisyn J, Strokosch G. Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase. Am J Hum Genet 1988; 43:414-421
    • (1988) Am J Hum Genet , vol.43 , pp. 414-421
    • Kang, S.S.1    Zhou, J.2    Wong, P.W.3    Kowalisyn, J.4    Strokosch, G.5
  • 8
    • 0028487161 scopus 로고
    • Human methylenetetrahydrofolate reductase: Isolation of cDNA, mapping and mutation identification
    • Goyette P, Sumner JS, Milos R, et al. Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification. Nat Genet 1994;7:195-200
    • (1994) Nat Genet , vol.7 , pp. 195-200
    • Goyette, P.1    Sumner, J.S.2    Milos, R.3
  • 9
    • 0030027668 scopus 로고    scopus 로고
    • Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations
    • Jacques PF, Bostom AG, Williams RR, et al. Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation 1996;93:7-9
    • (1996) Circulation , vol.93 , pp. 7-9
    • Jacques, P.F.1    Bostom, A.G.2    Williams, R.R.3
  • 10
    • 0029655724 scopus 로고    scopus 로고
    • Molecular genetic analysis in mild hyperhomocysteinemia: A common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease
    • Kluijtmans LA, van den Heuvel LP, Boers GH, et al. Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am J Hum Genet 1996;58:35-41
    • (1996) Am J Hum Genet , vol.58 , pp. 35-41
    • Kluijtmans, L.A.1    Van Den Heuvel, L.P.2    Boers, G.H.3
  • 11
    • 0027234122 scopus 로고
    • Homocysteinemia: Association of a metabolic disorder with vascular disease and thrombosis
    • Rees MM, Rodgers GM. Homocysteinemia: association of a metabolic disorder with vascular disease and thrombosis. Thromb Res 1993;71:337-359
    • (1993) Thromb Res , vol.71 , pp. 337-359
    • Rees, M.M.1    Rodgers, G.M.2
  • 12
    • 0033547440 scopus 로고    scopus 로고
    • Prevention of neural-tube defects with folic acid in China
    • China-U.S. Collaborative Project for Neural Tube Defect Prevention
    • Berry RJ, Li Z, Erickson JD, et al. Prevention of neural-tube defects with folic acid in China. China-U.S. Collaborative Project for Neural Tube Defect Prevention. N Engl J Med 1999;341:1485-1490
    • (1999) N Engl J Med , vol.341 , pp. 1485-1490
    • Berry, R.J.1    Li, Z.2    Erickson, J.D.3
  • 15
    • 0034679870 scopus 로고    scopus 로고
    • Absence of association between a common mutation in the methylenetetrahydrofolate reductase gene and preeclampsia in Japanese
    • Kobashi G, Yamada H, Asano T, et al. Absence of association between a common mutation in the methylenetetrahydrofolate reductase gene and preeclampsia in Japanese. Am J Med Genet 2000;93:122-125
    • (2000) Am J Med Genet , vol.93 , pp. 122-125
    • Kobashi, G.1    Yamada, H.2    Asano, T.3
  • 16
    • 0343471524 scopus 로고    scopus 로고
    • Genetic risk factor for unexplained recurrent early pregnancy loss
    • Nelen WL, Steegers EA, Eskes TK, Blom HJ. Genetic risk factor for unexplained recurrent early pregnancy loss. Lancet 1997;350:861
    • (1997) Lancet , vol.350 , pp. 861
    • Nelen, W.L.1    Steegers, E.A.2    Eskes, T.K.3    Blom, H.J.4
  • 17
    • 0031883045 scopus 로고    scopus 로고
    • A woman with five consecutive fetal deaths: Case report and retrospective analysis of hyperhomocysteinemia prevalence in 100 consecutive women with recurrent miscarriages
    • Quere I, Bellet H, Hoffet M, Janbon C, Mares P, Gris JC. A woman with five consecutive fetal deaths: case report and retrospective analysis of hyperhomocysteinemia prevalence in 100 consecutive women with recurrent miscarriages. Fertil Steril 1998;69:152-154
    • (1998) Fertil Steril , vol.69 , pp. 152-154
    • Quere, I.1    Bellet, H.2    Hoffet, M.3    Janbon, C.4    Mares, P.5    Gris, J.C.6
  • 18
    • 0032891393 scopus 로고    scopus 로고
    • The C677T MTHFR gene mutation is not predictive of risk for recurrent fetal loss
    • Holmes ZR, Regan L, Chilcott I, Cohen H. The C677T MTHFR gene mutation is not predictive of risk for recurrent fetal loss. Br J Haematol 1999;105:98-101
    • (1999) Br J Haematol , vol.105 , pp. 98-101
    • Holmes, Z.R.1    Regan, L.2    Chilcott, I.3    Cohen, H.4
  • 19
    • 0033754115 scopus 로고    scopus 로고
    • Primary habitual abortions are associated with high frequency of factor V Leiden mutation
    • Wramsby ML, Stein-Linder, Bremme K. Primary habitual abortions are associated with high frequency of factor V Leiden mutation. Fertil Steril 2000;74:987-991
    • (2000) Fertil Steril , vol.74 , pp. 987-991
    • Wramsby, M.L.1    Stein-Linder2    Bremme, K.3
  • 20
    • 0033955432 scopus 로고    scopus 로고
    • Factor V Leiden and prothrombin G20210A mutations, but not methylenetetrahydrofolate reductase C677T, are associated with recurrent miscarriages
    • Fokka ZJ, Lambropoulos AF, Saravelos H, et al. Factor V Leiden and prothrombin G20210A mutations, but not methylenetetrahydrofolate reductase C677T, are associated with recurrent miscarriages. Hum Reprod 2000;15:458-462
    • (2000) Hum Reprod , vol.15 , pp. 458-462
    • Fokka, Z.J.1    Lambropoulos, A.F.2    Saravelos, H.3
  • 21
    • 0036021465 scopus 로고    scopus 로고
    • Mutations in the factor V, prothrombin and MTHFR genes are not risk factors for recurrent fetal loss
    • Dilley A, Benito C, Hooper WC, et al. Mutations in the factor V, prothrombin and MTHFR genes are not risk factors for recurrent fetal loss. J Matern Fetal Neonatal Med 2002; 11:176-182
    • (2002) J Matern Fetal Neonatal Med , vol.11 , pp. 176-182
    • Dilley, A.1    Benito, C.2    Hooper, W.C.3
  • 22
    • 0035989412 scopus 로고    scopus 로고
    • Prevalence of genetic markers for thrombophilia in recurrent pregnancy loss
    • Carp H, Salomon O, Seidman D, Dardik R, Rosenberg N, Inbal A. Prevalence of genetic markers for thrombophilia in recurrent pregnancy loss. Hum Reprod 2002;17:1633-1637
    • (2002) Hum Reprod , vol.17 , pp. 1633-1637
    • Carp, H.1    Salomon, O.2    Seidman, D.3    Dardik, R.4    Rosenberg, N.5    Inbal, A.6
  • 24
    • 0033431657 scopus 로고    scopus 로고
    • The factor V Leiden mutation is not a common cause of pregnancy-induced hypertension in Japan
    • Kobashi G, Yamada H, Asano T, et al. The factor V Leiden mutation is not a common cause of pregnancy-induced hypertension in Japan. Semin Thromb Hemost 1999;25: 487-489
    • (1999) Semin Thromb Hemost , vol.25 , pp. 487-489
    • Kobashi, G.1    Yamada, H.2    Asano, T.3
  • 26
    • 0034442048 scopus 로고    scopus 로고
    • The epidemiology of recurrent pregnancy loss
    • Cramer DW, Wise LA. The epidemiology of recurrent pregnancy loss. Semin Reprod Med 2000;18:331-339
    • (2000) Semin Reprod Med , vol.18 , pp. 331-339
    • Cramer, D.W.1    Wise, L.A.2
  • 27
    • 0025892585 scopus 로고
    • Caffeine consumption during pregnancy and spontaneous abortion
    • Fenster L, Eskenazi B, Windham GC, Swan SH. Caffeine consumption during pregnancy and spontaneous abortion. Epidemiology 1991;2:168-174
    • (1991) Epidemiology , vol.2 , pp. 168-174
    • Fenster, L.1    Eskenazi, B.2    Windham, G.C.3    Swan, S.H.4
  • 28
    • 1642580722 scopus 로고    scopus 로고
    • Glutathione S-transferase M1 and T1 polymorphisms and the risk of recurrent pregnancy loss
    • Sata F, Yamada H, Kondo T, Fujimoto S, Kishi R. Glutathione S-transferase M1 and T1 polymorphisms and the risk of recurrent pregnancy loss. Mol Hum Reprod 2003; 9:165-169
    • (2003) Mol Hum Reprod , vol.9 , pp. 165-169
    • Sata, F.1    Yamada, H.2    Kondo, T.3    Fujimoto, S.4    Kishi, R.5
  • 30
    • 0035141812 scopus 로고    scopus 로고
    • The carriage of proinflammatory cytokine gene polymorphisms in recurrent pregnancy loss
    • Reid JG, Simpson NA, Walker RG, et al. The carriage of proinflammatory cytokine gene polymorphisms in recurrent pregnancy loss. Am J Reprod Immunol 2001;45:35-40
    • (2001) Am J Reprod Immunol , vol.45 , pp. 35-40
    • Reid, J.G.1    Simpson, N.A.2    Walker, R.G.3
  • 31
    • 0035056392 scopus 로고    scopus 로고
    • Interleukin 1 receptor antagonist polymorphism in women with idiopathic recurrent miscarriage
    • Unfried G, Tempfer C, Schneeberger C, Widmar B, Nagele F, Huber JC. Interleukin 1 receptor antagonist polymorphism in women with idiopathic recurrent miscarriage. Fertil Steril 2001;75:683-687
    • (2001) Fertil Steril , vol.75 , pp. 683-687
    • Unfried, G.1    Tempfer, C.2    Schneeberger, C.3    Widmar, B.4    Nagele, F.5    Huber, J.C.6
  • 32
    • 0036480136 scopus 로고    scopus 로고
    • T helper 1-type immunity to trophoblast antigens in women with a history of recurrent pregnancy loss is associated with polymorphism of the IL1B promoter region
    • Wang ZC, Yunis EJ, De los Santos MJ, Xiao L, Anderson DJ, Hill JA. T helper 1-type immunity to trophoblast antigens in women with a history of recurrent pregnancy loss is associated with polymorphism of the IL1B promoter region. Genes Immun 2002;3:38-42
    • (2002) Genes Immun , vol.3 , pp. 38-42
    • Wang, Z.C.1    Yunis, E.J.2    De Los Santos, M.J.3    Xiao, L.4    Anderson, D.J.5    Hill, J.A.6
  • 33
    • 0037326136 scopus 로고    scopus 로고
    • A polymorphism of the interleukin-6 gene promoter and idiopathic recurrent miscarriage
    • Unfried G, Bocskor S, Endler G, Nagele F, Huber JC, Tempfer CB. A polymorphism of the interleukin-6 gene promoter and idiopathic recurrent miscarriage. Hum Reprod 2003;18:267-270
    • (2003) Hum Reprod , vol.18 , pp. 267-270
    • Unfried, G.1    Bocskor, S.2    Endler, G.3    Nagele, F.4    Huber, J.C.5    Tempfer, C.B.6
  • 34
    • 0033754115 scopus 로고    scopus 로고
    • Primary habitual abortions are associated with high frequency of factor V Leiden mutation
    • Wramsby ML, Sten-Linder M, Bremme K. Primary habitual abortions are associated with high frequency of factor V Leiden mutation. Fertil Steril 2000;74:987-991
    • (2000) Fertil Steril , vol.74 , pp. 987-991
    • Wramsby, M.L.1    Sten-Linder, M.2    Bremme, K.3
  • 35
    • 0034919759 scopus 로고    scopus 로고
    • Thrombophilic gene mutations and recurrent spontaneous abortion: Prothrombin mutation increases the risk in the first trimester
    • Pihusch R, Buchholz T, Lohse P, et al. Thrombophilic gene mutations and recurrent spontaneous abortion: prothrombin mutation increases the risk in the first trimester. Am J Reprod Immunol 2001;46:124-131
    • (2001) Am J Reprod Immunol , vol.46 , pp. 124-131
    • Pihusch, R.1    Buchholz, T.2    Lohse, P.3
  • 36
    • 0035216735 scopus 로고    scopus 로고
    • HLA-G genotypes and pregnancy outcome in couples with unexplained recurrent miscarriage
    • Aldrich CL, Stephenson MD, Karrison T, et al. HLA-G genotypes and pregnancy outcome in couples with unexplained recurrent miscarriage. Mol Hum Reprod 2001;7: 1167-1172
    • (2001) Mol Hum Reprod , vol.7 , pp. 1167-1172
    • Aldrich, C.L.1    Stephenson, M.D.2    Karrison, T.3
  • 37
    • 0032870680 scopus 로고    scopus 로고
    • Polymorphism for mutation of cytosine to thymine at location 677 in the methylenetetrahydrofolate reductase gene is associated with recurrent early fetal loss
    • Lissak A, Sharon A, Fruchter O, Kassel A, Sanderovitz J, Abramovici H. Polymorphism for mutation of cytosine to thymine at location 677 in the methylenetetrahydrofolate reductase gene is associated with recurrent early fetal loss. Am J Obstet Gynecol 1999;181:126-130
    • (1999) Am J Obstet Gynecol , vol.181 , pp. 126-130
    • Lissak, A.1    Sharon, A.2    Fruchter, O.3    Kassel, A.4    Sanderovitz, J.5    Abramovici, H.6
  • 38
    • 0037443934 scopus 로고    scopus 로고
    • Thrombophilic disorders and fetal loss: A meta-analysis
    • Rey E, Kahn SR, David M, Shrier I. Thrombophilic disorders and fetal loss: a meta-analysis. Lancet 2003;361:901-908
    • (2003) Lancet , vol.361 , pp. 901-908
    • Rey, E.1    Kahn, S.R.2    David, M.3    Shrier, I.4
  • 39
    • 17344372005 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase gene polymorphism and ischemic stroke in Japanese
    • Morita H, Kurihara H, Tsubaki S, et al. Methylenetetrahydrofolate reductase gene polymorphism and ischemic stroke in Japanese. Arterioscler Thromb Vasc Biol 1998;18:1465-1469
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1465-1469
    • Morita, H.1    Kurihara, H.2    Tsubaki, S.3
  • 40
    • 0034606262 scopus 로고    scopus 로고
    • The homozygous C677T mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for migraine
    • Kowa H, Yasui K, Takeshima T, Urakami K, Sakai F, Nakashima K. The homozygous C677T mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for migraine. Am J Med Genet 2000;96:762-764
    • (2000) Am J Med Genet , vol.96 , pp. 762-764
    • Kowa, H.1    Yasui, K.2    Takeshima, T.3    Urakami, K.4    Sakai, F.5    Nakashima, K.6
  • 41
    • 0035660287 scopus 로고    scopus 로고
    • Association of methylenetetrahydrofolate reductase polymorphism C677T and dietary folate with the risk of cervical dysplasia
    • Goodman MT, McDuffie K, Hernandez B, et al. Association of methylenetetrahydrofolate reductase polymorphism C677T and dietary folate with the risk of cervical dysplasia. Cancer Epidemiol Biomarkers Prev 2001;10:1275-1280
    • (2001) Cancer Epidemiol Biomarkers Prev , vol.10 , pp. 1275-1280
    • Goodman, M.T.1    McDuffie, K.2    Hernandez, B.3
  • 42
    • 0029939676 scopus 로고    scopus 로고
    • Homocysteine and vascular disease
    • McCully KS. Homocysteine and vascular disease. Nat Med 1996;2:386-389
    • (1996) Nat Med , vol.2 , pp. 386-389
    • McCully, K.S.1
  • 43
    • 0032771090 scopus 로고    scopus 로고
    • Folic acid and homocyst(e)ine metabolic defects and the risk of placental abruption, pre-eclampsia and spontaneous pregnancy loss: A systematic review
    • Ray JG, Laskin CA. Folic acid and homocyst(e)ine metabolic defects and the risk of placental abruption, pre-eclampsia and spontaneous pregnancy loss: a systematic review. Placenta 1999;20:519-529
    • (1999) Placenta , vol.20 , pp. 519-529
    • Ray, J.G.1    Laskin, C.A.2
  • 44
    • 0030897112 scopus 로고    scopus 로고
    • Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease
    • Morita H, Taguchi J, Kurihara H, et al. Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease. Circulation 1997; 95:2032-2036
    • (1997) Circulation , vol.95 , pp. 2032-2036
    • Morita, H.1    Taguchi, J.2    Kurihara, H.3
  • 45
    • 0030925844 scopus 로고    scopus 로고
    • Resistance to activated protein C and Arg 503 Gln factor V mutation are uncommon in eastern Asian populations
    • Kodaira H, Ishida F, Shimodaira S, Takamiya O, Furihata K, Kitano K. Resistance to activated protein C and Arg 503 Gln factor V mutation are uncommon in eastern Asian populations. Acta Haematologica 1997;98:22-25
    • (1997) Acta Haematologica , vol.98 , pp. 22-25
    • Kodaira, H.1    Ishida, F.2    Shimodaira, S.3    Takamiya, O.4    Furihata, K.5    Kitano, K.6
  • 46
    • 0034036664 scopus 로고    scopus 로고
    • Identification of 187 single nucleotide polymorphisms (SNPs) among 41 candidate genes for ischemic heart disease in the Japanese population
    • Ohnishi Y, Tanaka T, Yamada R, et al. Identification of 187 single nucleotide polymorphisms (SNPs) among 41 candidate genes for ischemic heart disease in the Japanese population. Hum Genet 2000;106:288-292
    • (2000) Hum Genet , vol.106 , pp. 288-292
    • Ohnishi, Y.1    Tanaka, T.2    Yamada, R.3


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