The factor V Leiden mutation is not a common cause of pregnancy-induced hypertension in Japan

Seminars in Thrombosis and Hemostasis

Volumn 25, Issue 5, 1999, Pages 487-489

  Kobashi, Gen ^a   Yamada, Hideto ^a   Asano, Toshimichi ^a   Nagano, Shunsuke ^a   Hata, Akira ^a   Kishi, Reiko ^a   Kondo, Kiyotaro ^b   Fujimoto, Seiichiro ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b OPEN UNIVERSITY OF JAPAN   (Japan)

Author keywords

Factor V Leiden mutation; Preeclampsia; Pregnancy induced hypertension; Thrombosis

Indexed keywords

ACTIVATED PROTEIN C; ARGININE; BLOOD CLOTTING FACTOR 5 LEIDEN; GLUTAMINE;

ACTIVATED PROTEIN C RESISTANCE; ADULT; ARTICLE; BLOOD CLOTTING; CONTROLLED STUDY; FEMALE; GENE MUTATION; GENOTYPE; HUMAN; JAPAN; MAJOR CLINICAL STUDY; MATERNAL HYPERTENSION; PREECLAMPSIA; PRIORITY JOURNAL; RISK FACTOR; THROMBOSIS;

EID: 0033431657     PISSN: 00946176     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-994955     Document Type: Article

References (13)

1. Bertina RM, Koeleman BPC, Koster T, et al. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994;369:64-67
2. Kodaira H, Ishida F, Shimodaira S, Takamiya O, Furihata K, Kitano K. Resistance to activated protein C and Arg 503 Gln factor V mutation are uncommon in eastern Asian populations. Acta Haematol 1997;98:22-25
3. Dizon-Townson DS, Nelson LM, Easton K, Ward K. The factor V Leiden mutation may predispose women to severe preeclampsia. Am J Obstet Gynecol 1996;175:902-905
4. Grandone E, Margaglione M, Colaizzo D, et al. The factor V Leiden, C>T MTHFR polymorphism and genetic susceptibility to preeclampsia. Thromb Haemost 1997;77:1052-1054
5. Davies JA, Prentice CRM. Coagulation changes in pregnancy-induced hypertension and growth retardation. In: Greer IA, Turpie AGG, Forbes CD eds. Haemostasis and Thrombosis in Obstetrics and Gynecology. London: Chapman and Hall; 1992:143-162
6. National High Blood Pressure Education Program Working Group. Report on high blood pressure in pregnancy (Consensus Report). Am J Obstet Gynecol 1990;163:1689-1712.
7. Dekker GA, de Vries JIP, Doelitzsch PM, et al. Underlying disorders associated with severe early-onset preeclampsia. Am J Obstet Gynecol 1995;173:1042-1048.
8. Chesley LC. History and epidemiology of preeclampsia-eclampsia. Clin Obstet Gynecol 1984;27:801-820
9. Eskenazi B, Fenster L, Sidney S. A multivariate analysis of risk factors for preeclampsia. JAMA 1991;266:237-241.
10. Ward K, Hata A, Jeunemaitre X, et al. A molecular variant of angiotensinogen associated with preeclampsia. Nat Genet 1993; 4:59-61
11. Kobashi G, Hata A, Fujimoto S. Association of pregnancy-induced hypertension with a molecular variant of angiotensinogen gene. Acta Obstet Gynecol Jpn 1995;47:497-498
12. Furuhashi N. Several issues in the classification of preeclampsia at the present time. Journal of Japan Society for the Study of Toxemia of Pregnancy 1996;4:31-34
13. Dizon-Townson DS, Kinney S, Branch DW, Ward K. The factor V Leiden mutation is not a common cause of recurrent miscarriage. J Reprod Immunol 1997;34:217-223