Interleukin 1 receptor antagonist polymorphism in women with idiopathic recurrent miscarriage

Fertility and Sterility

Volumn 75, Issue 4, 2001, Pages 683-687

  Unfried, Gertrud ^a   Tempfer, Clemens ^a   Schneeberger, Christian ^a   Widmar, Barbara ^a   Nagele, Fritz ^a,b   Huber, Johannes C ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Idiopathic recurrent miscarriage; Interleukin 1 receptor antagonist; Polymorphism; Risk factor

Indexed keywords

INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; HUMAN; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RECURRENT ABORTION; RISK FACTOR; SPONTANEOUS ABORTION;

ABORTION, HABITUAL; ABORTION, SPONTANEOUS; ALLELES; CASE-CONTROL STUDIES; CONFIDENCE INTERVALS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GESTATIONAL AGE; HETEROZYGOTE; HOMOZYGOTE; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; ODDS RATIO; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PREGNANCY; PREGNANCY TRIMESTER, SECOND; RECEPTORS, INTERLEUKIN-1; REFERENCE VALUES; SIALOGLYCOPROTEINS;

EID: 0035056392     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(01)01675-2     Document Type: Article

References (43)

1. The prognostic value of anti-paternal antibodies and leukocyte immunization on the proportion of live births in couples with consecutive recurrent miscarriages
2. Etiologies and subsequent reproductive performance of 100 couples with recurrent abortion
3. Efficacy of progesterone support for pregnancy in women with recurrent miscarriage. A meta-analysis of controlled trials
4. Recurrent pregnancy loss; an update
5. Serum androgen levels in women who have recurrent miscarriages and their correlation with markers of endometrial function
6. Hyperhomocysteinemia; a risk factor in women with unexplained recurrent early pregnancy loss
7. Antibodies to Chlamydia trachomatis in sera of women with recurrent spontaneous abortions
8. Translocations are infrequent among couples having repeated spontaneous abortions but no other abnormal pregnancies
9. A worldwide collaborative observational study and metaanalysis on allogenic leukocyte immunotherapy for recurrent spontaneous abortion
10. Prevalence and heterogeneity of antiphosphatidylethanolamine antibodies in patients with recurrent early pregnancy losses
11. Thyroid antibody titer and avidity in patients with recurrent miscarriage
12. Immunopathologic factors contributing to recurrent spontaneous abortions in humans
13. Maternal TH1-and TH2-type reactivity to placental antigens in normal human pregnancy and unexplained recurrent spontaneous abortions
14. A progesterone-dependent immunomodulatory protein alters the TH1/TH2 balance
15. Alterations in humoral immune responses associated with recurrent pregnancy loss
16. Prevention of allogeneic fetal rejection by tryptophan catabolism
17. Evidence of a TH1 type response associated with recurrent miscarriage
18. Biology of interleukin-1
19. Inflammatory cytokines; interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases
20. Allelic polymorphism in IL-1β and IL-1 receptor antagonist (IL-1RA) genes in inflammatory bowel disease
21. Association of interleukin-1 beta and interleukin-1 receptor antagonist genes with disease severity in MS
22. Presence of IL-1RA allele 2 is associated with enhanced IL-1β production in vitro
23. The human IL-1 receptor antagonist gene maps to chromosome 2q14-21 in the region of the IL-1 loci
24. Polymorphism in human IL-1 receptor antagonist gene intron 2 is caused by variable numbers of an 86-bp tandem repeat
25. Interleukin 1 receptor antagonist gene polymorphism in women with vulvar vestibulitis
26. Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukin-1 receptor antagonist
27. Severity of alopecia areata is associated with a polymorphism in the interleukin-1 receptor antagonist gene
28. Familial recurrent spontaneous abortions
29. Familial skewed X inactivation; a molecular trait associated with high spontaneous-abortion rate maps to Xq28
30. HLA-sharing, recurrent spontaneous abortion, and the genetic hypothesis
31. Factor V Leiden and prothrombin G 20210 A mutations, but not methlenetetrahydrofolate reductase C 677T, are associated with recurrent miscarriages
32. Factor V Leiden and factor II G20210A mutations in patients with recurrent abortion
33. Thrombophilic polymorphisms are common in women with fetal loss without apparent cause
34. Hypercoagulable state mutation analysis in white patients with early first-trimester recurrent pregnancy loss
35. The C677T MTHFR gene mutation is not predictive of risk for recurrent fetal loss
36. Genetic control of fertility and embryonic waste in the mouse; a role for angiotensinogen
37. Bidirectional cytokine interaction in maternal-fetal relationship; is successful pregnancy a TH2 phenomenon?
38. Soluble receptors neutralizing TNF-alpha and IL-1 block stress-triggered murine abortion
39. Altered interleukin 12 and nitric oxide levels in recurrent miscarriage
40. Inhibition of T cell proliferation by macrophage tryptophan catabolism
41. Successful treatment of immunologic abortion with low-dose intravenous immunoglobulin
42. Habitual abortions in 678 healthy patients; investigation and prevention