Targeted deletion of the integrin β4 signaling domain suppresses laminin-5-dependent nuclear entry of mitogen-activated protein kinases and NF-κB, causing defects in epidermal growth and migration

Molecular and Cellular Biology

Volumn 25, Issue 14, 2005, Pages 6090-6102

  Nikolopoulos, Sotiris N ^a   Blaikie, Pamela ^a   Yoshioka, Toshiaki ^a   Guo, Wenjun ^a   Puri, Claudia ^b   Tacchetti, Carlo ^b   Giancotti, Filippo G ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA6BETA4 INTEGRIN; EPIDERMAL GROWTH FACTOR; FIBRONECTIN; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KALININ; MATRIX PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASEMENT MEMBRANE; CELL GROWTH; CELL MIGRATION; CELL NUCLEUS; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; EPIDERMIS; GENE DELETION; HEMIDESMOSOME; HYPOPLASIA; KERATINOCYTE; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; WOUND HEALING;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; APOPTOSIS; CELL ADHESION; CELL ADHESION MOLECULES; CELL MOVEMENT; CELL NUCLEUS; EPIDERMAL GROWTH FACTOR; EPIDERMIS; GENE DELETION; GENE TARGETING; INTEGRIN ALPHA6BETA4; INTEGRIN BETA4; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KERATINOCYTES; MICE; MICE, MUTANT STRAINS; NF-KAPPA B; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; WOUND HEALING;

EID: 21744455891     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.25.14.6090-6102.2005     Document Type: Article

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