α3β1 and ↑β4 integrin receptors for laminin-5 are not essential for epidermal morphogenesis and homeostasis during skin development

Journal of Cell Science

Volumn 113, Issue 17, 2000, Pages 3051-3062

  DiPersio, C M ^a   van der Neut, R ^a   Georges Labouesse, E ^a   Kreidberg, J A ^a   Sonnenberg, A ^a   Hynes, R O ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

Author keywords

Epidermis; Extracellular matrix; Integrin

Indexed keywords

INTEGRIN RECEPTOR; KALININ; PROTEIN SUBUNIT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BASEMENT MEMBRANE; BLISTER; CELL ADHESION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DERMOEPIDERMAL JUNCTION; DISEASE SEVERITY; EMBRYO; EMBRYO DEVELOPMENT; EPIDERMIS; EXTRACELLULAR MATRIX; GENE MUTATION; HOMEOSTASIS; KERATINOCYTE; LIGAND BINDING; MATURATION; MORPHOGENESIS; MOUSE; MUTANT; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; RECEPTOR BINDING; REGULATORY MECHANISM; SKIN; TISSUE REGENERATION;

ANIMALIA;

EID: 0033828682     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.113.17.3051     Document Type: Article

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13. Distinct and overlapping ligand specificities of the α3Aβ1 and α6Aβ1 integrins: Recognition of laminin isoforms
14. α3β1 integrin is required for normal development of the epidermal basement membrane
15. Mouse keratinocytes immortalized with large T antigen acquire α3β1 integrin-dependent secretion of MMP-9/gelatinase B
16. β4 integrin is required for hemidesmosomal formation, cell adhesion and cell survival
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27. Epithelial stem cells
28. A homozygous nonsense mutation in the α3 chain gene of laminin 5 (LAMA3) in lethal (Herlitz) junctional epidermolysis bullosa
29. Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis
30. IAP insertion in the murine LamB3 gene results in junctional epidermolysis bullosa
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32. The coupling of α6β4 integrin to the Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation
33. Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin β4 cytoplasmic domain
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35. Human colonic cancer cells synthesize and adhere to laminin-5. Their adhesion to laminin-5 involves multiple receptors among which is integrin alpha2beta1
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37. A homozygous nonsense mutation in the beta 3 chain gene of laminin 5 (LAMB3) in Herlitz junctional epidermolysis bullosa
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40. Targeted disruption of the LAMA3 gene in mice reveals abnormalities in survival and late stage differentiation of epithelial cells
41. Activation of phosphoinositide 3-OH kinase by the α6β4 integrin promotes carcinoma invasion
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44. The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin α6β4 and may regulate the spatial organization of hemidesmosomes
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