c-Jun is essential for organization of the epidermal leading edge

Developmental Cell

Volumn 4, Issue 6, 2003, Pages 865-877

  Li, Guochun ^a   Gustafson Brown, Cindy ^a   Hanks, Steven K ^b   Nason, Katie ^c   Arbeit, Jeffrey M ^c   Pogliano, Kit ^a   Wisdom, Ronald M ^d   Johnson, Randall S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VANDERBILT INGRAM CANCER CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; LIGAND; PROTEIN C JUN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; CELL ASSAY; CELL CULTURE; CELL ELONGATION; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; EMBRYO; EPIDERMIS CELL; EYELID DISEASE; GENE DELETION; HISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTO ONCOGENE; SIGNAL TRANSDUCTION; WOUND HEALING IMPAIRMENT;

ANIMALS; CELL DIVISION; CELL MOVEMENT; CELLS, CULTURED; EPIDERMAL GROWTH FACTOR; EPIDERMIS; EYELIDS; GENE DELETION; GENES, JUN; KERATINOCYTES; KERATINS; MICE; MICE, TRANSGENIC; MUTATION; PHOSPHOPROTEIN PHOSPHATASE; PROLIFERATING CELL NUCLEAR ANTIGEN; RECEPTOR, EPIDERMAL GROWTH FACTOR; TIME FACTORS; TRANSCRIPTION FACTOR AP-1;

ANIMALIA;

EID: 0037567646     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1534-5807(03)00159-X     Document Type: Article

References (45)

1. Angel P. Szabowski A. Function of AP-1 target genes in mesenchymal-epithelial cross-talk in skin Biochem. Pharmacol. 64 2002 949-956
2. Angel P. Szabowski A. Schorpp-Kistner M. Function and regulation of AP-1 subunits in skin physiology and pathology Oncogene 20 2001 2413-2423
3. Behrens A. Sibilia M. Wagner E.F. Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation Nat. Genet. 21 1999 326-329
4. Berkowitz E.A. Seroogy K.B. Schroeder J.A. Russell W.E. Evans E.P. Riedel R.F. Phillips H.K. Harrison C.A. Lee D.C. Luetteke N.C. Characterization of the mouse transforming growth factor alpha gene: its expression during eyelid development and in waved 1 tissues Cell Growth Differ. 7 1996 1271-1282
5. Bernerd F. Magnaldo T. Freedberg I.M. Blumenberg M. Expression of the carcinoma-associated keratin K6 and the role of AP-1 proto-oncoproteins Gene Expr. 3 1993 187-199
6. Carroll J.M. Romero M.R. Watt F.M. Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis Cell 83 1995 957-968
7. Ellis P.D. Hadfield K.M. Pascall J.C. Brown K.D. Heparin-binding epidermal-growth-factor-like growth factor gene expression is induced by scrape-wounding epithelial cell monolayers: involvement of mitogen-activated protein kinase cascades Biochem. J. 354 2001 99-106
8. Findlater G.S. McDougall R.D. Kaufman M.H. Eyelid development, fusion and subsequent reopening in the mouse J. Anat. 183 1993 121-129
9. Fowler K.J. Walker F. Alexander W. Hibbs M.L. Nice E.C. Bohmer R.M. Mann G.B. Thumwood C. Maglitto R. Danks J.A.et-al. A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on receptor biochemistry that results in impaired lactation Proc. Natl. Acad. Sci. USA 92 1995 1465-1469
10. Fu S. Bottoli I. Goller M. Vogt P.K. Heparin-binding epidermal growth factor-like growth factor, a v-Jun target gene, induces oncogenic transformation Proc. Natl. Acad. Sci. USA 96 1999 5716-5721
11. Fuchs E. Beauty is skin deep: the fascinating biology of the epidermis and its appendages Harvey Lect. 94 1998 47-77
12. Hall A. Rho GTPases and the actin cytoskeleton Science 279 1998 509-514
13. Hauck C.R. Sieg D.J. Hsia D.A. Loftus J.C. Gaarde W.A. Monia B.P. Schlaepfer D.D. Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells Cancer Res. 61 2001 7079-7090
14. Jiang C.K. Magnaldo T. Ohtsuki M. Freedberg I.M. Bernerd F. Blumenberg M. Epidermal growth factor and transforming growth factor alpha specifically induce the activation- and hyperproliferation-associated keratins 6 and 16 Proc. Natl. Acad. Sci. USA 90 1993 6786-6790
15. Johnson A.C. Murphy B.A. Matelis C.M. Rubinstein Y. Piebenga E.C. Akers L.M. Neta G. Vinson C. Birrer M. Activator protein-1 mediates induced but not basal epidermal growth factor receptor gene expression Mol. Med. 6 2000 17-27
16. Jonkers J. Meuwissen R. van der Gulden H. Peterse H. van der Valk M. Berns A. Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer Nat. Genet. 29 2001 418-425
17. Juriloff D.M. Harris M.J. Mah D.G. Benson A. The lidgap-Gates (lgGa) mutation for open eyelids at birth maps to mouse chromosome 13 Mamm. Genome 7 1996 403-407
18. Kiehart D.P. Galbraith C.G. Edwards K.A. Rickoll W.L. Montague R.A. Multiple forces contribute to cell sheet morphogenesis for dorsal closure in Drosophila J. Cell Biol. 149 2000 471-490
19. Kockel L. Zeitlinger J. Staszewski L.M. Mlodzik M. Bohmann D. Jun in Drosophila development: redundant and nonredundant functions and regulation by two MAPK signal transduction pathways Genes Dev. 11 1997 1748-1758
20. Kockel L. Homsy J.G. Bohmann D. Drosophila AP-1: lessons from an invertebrate Oncogene 20 2001 2347-2364
21. Laderoute K.R. Calaoagan J.M. Gustafson-Brown C. Knapp A.M. Li G.C. Mendonca H.L. Ryan H.E. Wang Z. Johnson R.S. The response of c-jun/AP-1 to chronic hypoxia is hypoxia-inducible factor 1 alpha dependent Mol. Cell. Biol. 22 2002 2515-2523
22. Lamarche N. Tapon N. Stowers L. Burbelo P.D. Aspenstrom P. Bridges T. Chant J. Hall A. Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade Cell 87 1996 519-529
23. Li C. Guo H. Xu X. Weinberg W. Deng C.X. Fibroblast growth factor receptor 2 (Fgfr2) plays an important role in eyelid and skin formation and patterning Dev. Dyn. 222 2001 471-483
24. Luetteke N.C. Qiu T.H. Peiffer R.L. Oliver P. Smithies O. Lee D.C. TGF alpha deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice Cell 73 1993 263-278
25. Mann G.B. Fowler K.J. Gabriel A. Nice E.C. Williams R.L. Dunn A.R. Mice with a null mutation of the TGF alpha gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation Cell 73 1993 249-261
26. Martin P. Nobes C.D. An early molecular component of the wound healing response in rat embryos-induction of c-fos protein in cells at the epidermal wound margin Mech. Dev. 38 1992 209-215
27. Miettinen P.J. Berger J.E. Meneses J. Phung Y. Pedersen R.A. Werb Z. Derynck R. Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor Nature 376 1995 337-341
28. Nobes C.D. Hall A. Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia Cell 81 1995 53-62
29. Park J.M. Adam R.M. Peters C.A. Guthrie P.D. Sun Z. Klagsbrun M. Freeman M.R. AP-1 mediates stretch-induced expression of HB-EGF in bladder smooth muscle cells Am. J. Physiol. 277 1999 C294-C301
30. Passegue E. Jochum W. Behrens A. Ricci R. Wagner E.F. JunB can substitute for Jun in mouse development and cell proliferation Nat. Genet. 30 2002 158-166
31. Ramet M. Lanot R. Zachary D. Manfruelli P. JNK signaling pathway is required for efficient wound healing in Drosophila Dev. Biol. 241 2002 145-156
32. Rossi A. Jang S.I. Ceci R. Steinert P.M. Markova N.G. Effect of AP1 transcription factors on the regulation of transcription in normal human epidermal keratinocytes J. Invest. Dermatol. 110 1998 34-40
33. Ruest P.J. Roy S. Shi E. Mernaugh R.L. Hanks S.K. Phosphospecific antibodies reveal focal adhesion kinase activation loop phosphorylation in nascent and mature focal adhesions and requirement for the autophosphorylation site Cell Growth Differ. 11 2000 41-48
34. Ryan H.E. Poloni M. McNulty W. Elson D. Gassmann M. Arbeit J.M. Johnson R.S. Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth Cancer Res. 60 2000 4010-4015
35. ASchwartzberg P.L. Stall A.M. Hardin J.D. Bowdish K.S. Humaran T. Boast S. Harbison M.L. Robertson E.J. Goff S.P. Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations Cell 65 1991 1165-1175
36. Shirai K. Okada Y. Saika S. Senba E. Ohnishi Y. Expression of transcription factor AP-1 in rat lens epithelial cells during wound repair Exp. Eye Res. 73 2001 461-468
37. Singer A.J. Clark R.A. Cutaneous wound healing N. Engl. J. Med. 341 1999 738-746
38. Smilenov L.B. Mikhailov A. Pelham R.J. Marcantonio E.E. Gundersen G.G. Focal adhesion motility revealed in stationary fibroblasts Science 286 1999 1172-1174
39. Tomic-Canic M. Komine M. Freedberg I.M. Blumenberg M. Epidermal signal transduction and transcription factor activation in activated keratinocytes J. Dermatol. Sci. 17 1998 167-181
40. Tsuboi K. Yamaoka S. Maki M. Ohshio G. Tobe T. Hatanaka M. Soluble factors including proteinases released from damaged cells may trigger the wound healing process Biochem. Biophys. Res. Commun. 168 1990 1163-1170
41. Vassalli A. Matzuk M.M. Gardner H.A. Lee K.F. Jaenisch R. Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction Genes Dev. 8 1994 414-427
42. Yates S. Rayner T.E. Transcription factor activation in response to cutaneous injury: role of AP-1 in reepithelialization Wound Repair Regen. 10 2002 5-15
43. Young P.E. Richman A.M. Ketchum A.S. Kiehart D.P. Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function Genes Dev. 7 1993 29-41
44. Yujiri T. Ware M. Widmann C. Oyer R. Russell D. Chan E. Zaitsu Y. Clarke P. Tyler K. Oka Y. et al. MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation Proc. Natl. Acad. Sci. USA 97 2000 7272-7277
45. Zenz R. Kenner L. Martin P. Eferl R. Scheuch H. Wagner E.F. Eyelid-closure and skin tumor development are dependent on c-Jun regulating EGFR expression Dev. Cell In press 2003