Oxidative stress, aging, and aging-related diseases

Progress in Nutrition

Volumn 7, Issue 1, 2005, Pages 3-22

  Passi, Siro ^a,c   Ricci, R ^a   Aleo, E ^a   Cocchi, M ^b  

^a LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

^b SCOTTISH AGRICULTURAL COLLEGE   (United Kingdom)

^c IDI Farmaceutici   (Italy)

Author keywords

Aging and aging related diseses; Antioxidants; Oxidative stress; R; RNS; ROS

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; BIOLOGICAL MARKER; BLEOMYCIN; CELL DNA; COPPER; DOXORUBICIN; FREE RADICAL; GAMMA TOCOPHEROL; HYDROGEN PEROXIDE; IRON; NARCOTIC AGENT; NITROGEN; REACTIVE OXYGEN METABOLITE; RETINOL; SELENIUM; SUPEROXIDE DISMUTASE; UBIQUINONE; XENOBIOTIC AGENT; ZINC;

AGING; ANTIOXIDANT ACTIVITY; CELL ACTIVITY; CELL DAMAGE; DIET SUPPLEMENTATION; DNA DAMAGE; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL FACTOR; HUMAN; IN VIVO STUDY; LIPID DEGRADATION; MACROMOLECULE; MITOCHONDRIAL RESPIRATION; NONHUMAN; ONSET AGE; OXIDATION; OXIDATIVE STRESS; PROTEIN DEGRADATION; REVIEW; ULTRAVIOLET RADIATION;

EID: 21644443931     PISSN: 11298723     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (108)

1. Halliwell B, Gutteridge JMC. Free radicals in Biology and Medicine, 3rd edition. Oxford University Press, Midsomer Norton, Avon England. 1999.
2. Sohal RS, Weidruch R. Oxidative stress, caloric restriction and aging. Science 1996; 273: 59-64.
3. Martin GM, Austad SN, Johnson TE. Genetic analysis of ageing: role of oxidative damage and environmental stress. Nature Genet 1996; 13: 25-34.
4. Harman D. Aging, a theory based on free radical and radiation chemistry. J Gerontol 1956; 11: 298-300.
5. Harman D. The aging process. Proc Natl Acad Sci USA 1981; 78: 7124-8.
6. Cadenas E, Davies KJA. Mitochondrial free radical generation, oxidative stress, and aging. Free Radic Biol Med 2000; 29: 222-30.
7. Bohr VA. Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells. Free Radic Biol Med 2002; 32: 804-12.
8. Ames BN. DNA damage from micronutrient deficiencies is likely to be a major cause of cancer. Mutat Res 2001; 475: 7-20.
9. Bielski BHJ, Cabelli DE. Superoxide and hydroxyl radical chemistry in aqueous solution. In: Active Oxygen in Chemistry, Foote CS, Valentine JS, Greenberg A, Liebman JF eds. Chapman and Hall, London, 1995: 66-104.
10. Halliwell B, Clement MV, Long LH. Hydrogen peroxide in the human body. FEBS Lett 2000; 486: 10-3.
11. Czapski G, Goldstein S. The role of the reactions of NO with superoxide and oxygen in biological systems: a kinetic approach. Free Radic Biol Med 1995; 19: 785-94.
12. Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 2000; 408: 239-47.
13. Murphy MP, Pacher MA, Scariet JL, Martin SW. Peroxynitrite: a biologically significant oxidant. Gen Pharmacol 1998; 31: 179-86.
14. Nagy IZ. On the true role of oxygen free radicals in the living state, aging and degenerative disorders. Ann NY Acad Sci 2001; 928: 187-99.
15. Usmar VM. Cell signaling by reactive nitrogen and oxygen species in atherosclerosis. Free Radic Biol Med 2000; 28: 1780-94.
16. Brown NS, Bicknell R. Hypoxia and oxidative stress in breast cancer. Oxidative stress: Its effects on the growth, metastatic potential and response to therapy of breast cancer. Breast Cancer Res 2001; 3: 323-7.
17. Droge W. Free radicals in the physiological control of cell function. Physiol Rev 2002; 82: 47-95.
18. Nyska A, Dayan A, Maronpot RR. New tools in therapeutic research-prostatic cancer and models. Toxicol Pathol 2002; 30: 283-7.
19. Nyska A, Moomaw CR, Lomnitski L, Chan PC. Glutathione S-transferase pi expression in forestomach carcinogenesis process induced by gavage-administered 2,4-hexadienal in the F344 rat. Arch Toxicol 2001; 75: 618-24.
20. Hoffman JM, Grisham MB. Role of nitric oxide in inflammation. Acta Physiol Scand 2001; 173: 113-8.
21. Latha B, Babu M. The involvement of free radicals in burn injury: a review. Burns 2001; 27: 309-17.
22. Farre LF, Casado S. Heart failure, redox alterations, and endothelial dysfunction. Hypertension 2001; 38: 1400-5.
23. Najemnic C, Sinzinger H, Kritz H. Endothelial dysfunction, aterosclerosis and diabetes. Acta Med Austriaca 1999; 26: 148-53.
24. Blau S, Kohen R, Bass P, Rubinstein A. Relation between colonic inflammation severity and total low-molecular-weight antioxidant profile in experimental colitis. Dig Dis Sci 2000; 45: 1180-7.
25. Kohen R, Kakunda A, Rubinstein A. The role of cationized catalase and cationized glucose oxidase in mucosal oxidative damage induced in the rat jejunum. J Biol Chem 1992; 267: 21349-54.
26. Floyd RA. Antioxidants, oxidative stress, and degenerative neurological disorders. Proc Soc Exp Biol Medicina del Lavoro 1999; 222: 236-45.
27. Glasson BI, Ischiropoulos H, Lee VM, Trojanowski JQ. The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases. Free Radic Biol Med 2002; 32:1264-75.
28. Halliwell B. Role of free radicals in the neurodegenerative disease: therapeutic implications for antioxidant treatment. Drugs Aging 2001 18: 685-716.
29. Gilkun-Serki Y, Melamed E, Offen D. Oxidative stress induced-neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier. Neuropharmacol 2001; 40: 959-75.
30. Jenner P. Altered mitochondrial function, iron metabolism and glutathione levels in Parkinson's disease. Acta Neurol Scand Suppl 1993; 146: 6-13.
31. Canas PE. The role of xanthine oxidase and the effects of antioxidants in ischemia reperfusion cell injury. Acta Physiol Pharmacol Ther Latinoam 1999; 49: 13-20.
32. Gross GJ, Kersten JR, Warltier DC. Mechanisms of postischemic contractile dysfunction. Ann Thorac Surg 1999; 68: 1898-1904.
33. Tabakman R, Lazarovici P, Kohen R. Neuroprotective effects of carnosine and homocarnosine on pheochromocytoma PC12 cells exposed to ischemia. J Neurosci Res 2002; 68: 463-9.
34. Chiou GC. Review: effects of nitric oxide on eye diseases and their treatment. J Ocul Pharmacol Ther 2001; 17: 189-98.
35. Mercuri F, Quagliaro L, Ceriello A. Oxidative stress evaluation in diabetes. Diabetes Technol Ther 2000; 2: 589-600.
36. Lee HC, Wei YH. Mitochondrial alterations, cellular response to oxidative stress and defective degradation of proteins I aging. Biogerontology 2001; 2: 231-44.
37. Ornoy A, Zaken V, Kohen R. Role of reactive oxygen species ROS in the diabetes-induced anomalies in rat embryos in vitro: reduction in antioxidant enzymes and low-molecular-weight antioxidants LMWA may be causative factor for increased anomalies. Teratology 1999; 60: 376-86.
38. Lesnefsky EJ. Tissue iron overload and mechanisms of iron-catalyzed oxidative injury. Adv Exp Med Biol 1994; 366: 129-46.
39. Rotilio G, Carri M, Rossi L, Ciriolo MR. Copper-dependent oxidative stress and neurodegeneration. IUBMB Life 2000; 50: 309-14.
40. Strausak D, Mercer JF, Dieter HH, Stremmel W, Multthaup G. Copper in disorders with neurological symptoms: Alzheimer's, Menkes, and Wilson diseases. Brain Res Bull 2001; 55: 175-85.
41. Meral A, Tuncel P, Surmen-Gur E, Ozbek R, Ozturk E, Gunay U. Lipid peroxidation and antioxidant status in beta-thalassemia. Pediatr Hematol Oncol 2000; 17: 687-93.
42. Pentland AP. Active oxygen mechanisms of UV inflammation. Adv Exp Med Biol 1994; 366: 87-97.
43. Shadyro OI, Yurkova IL, Kisel MA. Radiation-induced peroxidation and fragmention of lipids in a model membrane. Int J Radiat 2002; 78: 211-7.
44. Victoria K. Review of the genotoxicity of nitrogen oxides. Mutat Res 1994; 317: 43-55.
45. Rav RS, Mehrotra S, Shanker U, Babu GS, Joshi PC, Hanss RK. Evaluation of UV-induced superoxide radical generation potential of some common antibiotics. Drug Chem Toxicol 2001; 24: 191-200.
46. Jones GM, Vale JA. Mechanisms of toxicity, clinical features, and management of diquat poisoning: a review. J Toxicol Clin Toxicol 2000; 38: 123-8.
47. Elsayed NM, Omaye ST, Klain GJ, et al. Free radical-mediated lung response to the monofunctional sulfur mustard butyl 2-chloroethyl sulfide after subcutaneous injection. Toxicology 1992: 72: 153-65.
48. Wormser U, Sintov A, Brodsky B et al. Topical iodine preparation as therapy against sulfur mustard-induced skin lesions. Toxicol Appl Pharmacol 2000; 169: 33-9.
49. Ames BN. Food constituents as a source of mutagens, carcinogens, and anticarcinogens. Pro Clin Biol Res 1986; 206: 3-32.
50. Kanner J, Lapidot. The stomach as a bioreactor: dietary lipid peroxidation in the gastric fluid and the effects of plant derived antioxidants. Free Radical Biol Med 2000; 31: 1388-95.
51. Srigiridhar K, Nair KM, Subramanian R, et al. Oral repletion of iron induces free radical mediated alterations in the gastrointestinal tract of rat. Mol Cell Biochem 2001; 219: 91-8.
52. Shaul PW. Regulation of endothelial nitric oxide synthase: location. Annu Rev Physiol 2002; 64: 749-74.
53. Kohen R, Nyska A. Oxidation of biological systems: oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification. Toxicol Pathol 2002; 306: 620-50.
54. Engelhard JF. Redox-mediated gene therapies for environmental injury: approaches and concepts. Antiox Redox Signal 1999; 1: 5-27.
55. Kaltschmidt B, Sparna T, Kaltschmidt C. Activation of NF-kB by reactive oxygen intermediates in the nervous system. Antioxid Redox Signal 1999; 1: 129-44.
56. Shackelford RE, Kaufmann WK, Paules RS. Oxidative stress and cell cycle checkpoint function. Free Radic Biol Med 2000; 28: 1387-404.
57. Gutteridge JM, Quinlan GJ, Kovacic P. Phagomimetic action of antimicrobial agents. Free Radic Res 1998; 28: 1-14.
58. Wolin MS. Interactions of oxidants with vascular signaling systems. Arterioscler Thromb Asc Biol 2000; 20: 1430-42.
59. Kuehl FA, Egan RW. Prostaglandins, arachidonic acid, and inflammation. Science 1980; 210: 978-84.
60. Saugstad OD. Update on oxygen radical disease in neonatology. Curr Opin Obster Gynecol 2001; 13: 147-53.
61. Benhar M, ngelberg D, Levitzki A. ROS, stress-activated kinases and stress signaling in cancer. EMBO Rep 2002; 3: 420-5.
62. Gutteridge JMC, Halliwell B. Antioxidants in nutrition, health, and disease. Oxford University Press, Oxford-New York-Tokio, 1994.
63. Atamna II, Cheumg I, Ame N. A method for detecting abasic sites in living cell: age-dependent changes in base excision repair. Proc Natl Acad Sci USA 2000; 197: 686-91.
64. Dizdaroglu M, Jaruga P, Birincioglu M, et al. Free radical-induced damage to DNA: mechanisms and measurement. Free Radic Biol Medicina del Lavoro 2002; 32: 1102-15.
65. Beal FM. Oxidatively modified proteins in aging and disease. Free Radical Biol Med 2002; 329: 797-803.
66. Szweda PA, Friguet B, Szweda L. Proteolysis, free radicals, and aging. Free Radical Biol Med 2002; 331: 29-36.
67. Cooney RV, Frankle AA, Harwood PJ, et al. α-Tocopherol detoxification of nitrogen dioxide: superiority to α-tocopherol. Proc Natl Acad Sci USA 1993; 90: 1771-5.
68. Goss SPA, Hogg N, Kalyanaramam B. The effect of α-tocopherol on the nitration of α-tocopherol by peroxynitrite, Arch Biochem Biophys 1999; 363: 333-40.
69. Saldeen T, Li D, Metha JL. Differential effect of alpha- and gamma-tocopherol on low-density lipoprotein oxidation, superoxide activity, platelet aggregation and arterial trombogenesis. J Am Coll Cardiol 1999; 34: 1208-15.
70. Passi S, Ippolito F. AIDS: nuova frontiera. Lombardo Editore, 1995.
71. Passi S. Progressive increase of oxidative stress in advancing human immunodeficiency. CONTINUUM 1998; 15 (4): 20-5.
72. Passi S, Stancato A, Cocchi M. Monitoraggio dello stress ossidativo nell'invecchiamento e nelle patologie ad esso correlate. Progress in Nutrition 2001; 31: 35-58.
73. Repola JM, Virtamo J, Eipatti S, et al. Randomized trial of alpha-tocopherol and betacarotene supplements on incidence of major coronary events in men with previous myocardial infarction. Lancet 1997; 349: 1715-20.
74. Goodman GE, Omenn GS, CARET Coinvestigators and Staff 1992. Carotene and retinol efficacy trial: Lung cancer chemoprevention trial in heavy cigarette smokers and asbestos-exposed workers. In "The Biology and Prevention of Aerodigestive Tract Cancers" Newell GR, Hong WK, eds pp 137-140. Plenum Press, New York.
75. Kalén A, Appelkvist EL, Dallner G. Age-related changes in the lipid composition of rat and human tissues. Lipids 1989; 24: 579-84.
76. Beckman KB, Ames BN. The free radical theory of aging matures. Physiol Rev 1998; 78: 547-81.
77. Borh VA. Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes in mammalian cells. Free Radical Biol Med 2002; 329: 804-12.
78. Stadtman ER. Protein oxidation and aging. Science 1992; 257: 1220-4.
79. Mason RP, Walter MF, Mason PE. Effect of oxidative stress on membrane structure: small angle X-ray diffraction analysis. Free Radical Biol Med 1997; 232: 419-25.
80. Terman A, Brunk UT. Lipofuscin: mechanism of formation and increase with aging. APMIS 1998; 106: 265-76.
81. Yin D. Biochemical basis of lipofuscin, ceroid and age pigment-like fluorophores. Free Rad Biol Med 1996; 21: 871-5.
82. Tirosh O, Kohen R, Katzhendler J, et al. Oxidative stress and effect in the integrity of lipid bilayers is modulated by cholesterol level of bilayers. Chem Phys Lipids 1997; 87:17-22.
83. Stadtman ER, Berlett BS. Reactive oxygen-mediated protein oxidation in aging and disease. Drug Metab Rev 1998; 30: 225-43.
84. Honda Smatsuo M. Life span shortening of the nematode Caenorhabditis elegans under higher concentrations of oxygen. Mech Ageing Dev 1992; 63: 235-46.
85. Honda Y, Honda S. The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans. FASEB J 1999; 13: 1385-93.
86. Gross L, Dreyfuss Y. Prevention of spontaneous and radiation-induced tumors in rats by reduction of food intake. Proc Natl Acad Sci USA 1990; 87: 6795-7.
87. Yu B, Masoro EJ, Murata I, et al. Life span study of SSPF Fisher 344 male rats fed ad libidum or restricted diets: longevity, growth, lean body mass and disease. J Gerontol 1982; 37: 130-41.
88. Sohal RS, Weindruch R. Oxidative stress, caloric restriction and aging. Science 1996; 273: 59-63.
89. Lee C, Klopp RG, Weindruch R, et al. Gene expression profile of aging and its retardation by caloric restriction. Science 1999; 285: 1390-3.
90. Shigenaga M, Hagen TM, Ames BN. Oxidative damage and mitochondrial decay in aging. Proc Natl Acad Sci USA 1994; 91:10771-8.
91. Jialal I, Traber M, Devaraj S. Gamma-tocopherol, the major form of vitamin E in the US diet, deserves more attention. Am J Clin Nutr 2001; 74: 714-22.
92. Cuzzocrea S, Riley DP, Caputi AP, Salvemini D. Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury. Pharmacol Rev 2001; 53: 135-59.
93. Digicsi V, Lenuzza M, Digiesi G. Prospects for the use of antioxidant therapy in the hypertension. Ann Ital Med Int 2001; 16: 93-100.
94. Rapola JM, Virtamo J, Eipatti S, et al. Randomised trial of alpha-tocopherol and beta-carotene supplements on incidence of major coronary events in men with previous myocardial infarction. Lancet 1997; 349: 1715-20.
95. Stepens NG, Parsons A, Schofield PM, Kelley F, Cheeseman K, Mitchinson MJ. Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study CHAOS. Lancet 1996; 347: 781-6.
96. Mayne ST. Antioxidant nutrients and cancer incidence and mortality: an epidemiologic perspective. Adv Pharmacol 1996; 38: 657-9.
97. Stephens NG, Parsons A, Schofield PM, Kelly F, Cheeseman K, Mitchinson MJ. Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet 1996; 347: 781-6.
98. Buring JE, Hennekens CH. Antioxidant vitamins and cardiovascular disease. Nutr Rev 1997; 55: 853-5.
99. Mason RP. In vitro and in vivo detection of free radicals metabolites with ESR.In: Free Radicals: A Practical Approach, Punchard NA, Kelly FJ eds. IRL Press, Oxford, England, 1996: 11-24.
100. Rice-Evans CA, Diplock AT, Symons MCR. Techniques in Free Radical Research, Elsevier, Amsterdam, 1991.
101. Gyllenhammar H. Lucigenin chemiluminescence in the assessment of neutrophil superoxide production. J Immunol Methods 1987; 97: 209-14.
102. Gotoh N, Niki E. Measurement of superoxide reaction by chemiluminescence. In "Methods in Enzymology. Nitric oxide". Edited by Packer L, Academic Press. 1999; 301: 471-83.
103. Halliwell B, Kaur H. Hydroxylation of salicylate and phenylalanine as assays for hydroxyl radicals: a cautionary note visited for the third time. Free Radic Res 1997; 27: 239-44.
104. Mihm MJ, Yu F, Weinstein DM, Reiser PJ, Bauer JA. Intracellular distribution of peroxynitrite during doxorubicin cardiomyopathy: evidence for selective impairment of myofibrillar creatine kinase. Br J Pharmacol 2002; 135: 581-8.
105. Fairbarian DW, Olive PL, O'Neill KL. The comet assay: a comprehensive review. Mutat Res 1995; 339: 37-59.
106. Sutherland JC, Monteleone DC, Trunk JG, et al. Quantifying DNA damage by gel electrophoresis, electronic imaging and number average length analysis. Electrophoresis 2001; 22: 843-54.
107. Levine RL, Wehr N, Williams JA, Stadtman ER, Shacter E. Determination of carbonyl groups in oxidized proteins. Methods Mol Biol 2000; 99: 15-24.
108. Esterbauer H. Estimation of peroxidative damage. A critical review. Pathol Biol 1996; 44: 25-8.