-
1
-
-
0037371361
-
Rho GTPase is activated by cytotoxic necrotizing factor 1 in peripheral blood T lymphocytes: Potential cytotoxicity for intestinal epithelial cells
-
Brest P, Mograbi B, Hofmann V, Loubat A, Rossi B, Auberger P, Hofmann P (2003) Rho GTPase is activated by cytotoxic necrotizing factor 1 in peripheral blood T lymphocytes: Potential cytotoxicity for intestinal epithelial cells. Infect Immun 71:1161-1169
-
(2003)
Infect Immun
, vol.71
, pp. 1161-1169
-
-
Brest, P.1
Mograbi, B.2
Hofmann, V.3
Loubat, A.4
Rossi, B.5
Auberger, P.6
Hofmann, P.7
-
2
-
-
0036156113
-
Role of the dermonecrotic toxin of Bordetella bronchiseptica in the pathogenesis of respiratory disease in swine
-
Brockmeier SL, Register KB, Magyar T, Lax AJ, Pullinger GD, Kunkle RA (2002) Role of the dermonecrotic toxin of Bordetella bronchiseptica in the pathogenesis of respiratory disease in swine. Infect Immun 70:481-490
-
(2002)
Infect Immun
, vol.70
, pp. 481-490
-
-
Brockmeier, S.L.1
Register, K.B.2
Magyar, T.3
Lax, A.J.4
Pullinger, G.D.5
Kunkle, R.A.6
-
3
-
-
0242592107
-
Structural elements required for deamidation of RhoA by cytotoxic necrotizing factor 1
-
Buetow L, Ghosh P (2003) Structural elements required for deamidation of RhoA by cytotoxic necrotizing factor 1. Biochemistry 42:12784-12791
-
(2003)
Biochemistry
, vol.42
, pp. 12784-12791
-
-
Buetow, L.1
Ghosh, P.2
-
4
-
-
0034953089
-
Structure of the Rho-activating domain of Escherichia coli cytotoxic necrotizing factor 1
-
Buetow L, Flatau G, Chiu K, Boquet P, Ghosh P (2001) Structure of the Rho-activating domain of Escherichia coli cytotoxic necrotizing factor 1. Nat Struct Biol 8:584-588
-
(2001)
Nat Struct Biol
, vol.8
, pp. 584-588
-
-
Buetow, L.1
Flatau, G.2
Chiu, K.3
Boquet, P.4
Ghosh, P.5
-
5
-
-
0842281652
-
Rho and Rac take center stage
-
Burridge K, Wennerberg K (2004) Rho and Rac take center stage. Cell 116:167-179
-
(2004)
Cell
, vol.116
, pp. 167-179
-
-
Burridge, K.1
Wennerberg, K.2
-
6
-
-
0033787469
-
Microbial toxins and the glucosylation of Rho family GTPases
-
Busch C, Aktories K (2000) Microbial toxins and the glucosylation of Rho family GTPases. Curr Opin Struct Biol 10:528-535
-
(2000)
Curr Opin Struct Biol
, vol.10
, pp. 528-535
-
-
Busch, C.1
Aktories, K.2
-
7
-
-
0032532623
-
Effect of cytotoxic necrotizing factor-1 on actin cytoskeleton in human monocytes: Role in the regulation of integrin-dependent phagocytosis
-
Capo C, Meconi S, Sanguedolce MV, Bardin N, Flatau G, Boquet P, Mege JL (1998) Effect of cytotoxic necrotizing factor-1 on actin cytoskeleton in human monocytes: Role in the regulation of integrin-dependent phagocytosis. J Immunol 161:4301-4308
-
(1998)
J Immunol
, vol.161
, pp. 4301-4308
-
-
Capo, C.1
Meconi, S.2
Sanguedolce, M.V.3
Bardin, N.4
Flatau, G.5
Boquet, P.6
Mege, J.L.7
-
8
-
-
0020658988
-
Partial purification and characterization of an Escherichia coli toxic factor that induces morphological cell alterations
-
Caprioli A, Falbo V, Roda LG, Ruggeri FM, Zona C (1983) Partial purification and characterization of an Escherichia coli toxic factor that induces morphological cell alterations. Infect Immun 39:1300-1306
-
(1983)
Infect Immun
, vol.39
, pp. 1300-1306
-
-
Caprioli, A.1
Falbo, V.2
Roda, L.G.3
Ruggeri, F.M.4
Zona, C.5
-
9
-
-
0038607907
-
37 kDa laminin receptor precursor modulates cytotoxic necrotizing factor 1-mediated RhoA activation and bacterial uptake
-
in press (M301028200)
-
Chung JW, Hong SJ, Kim KJ, Goti D, Stins MF, Shin S, Dawson VL, Dawson TM, Kim KS (2003) 37 kDa laminin receptor precursor modulates cytotoxic necrotizing factor 1-mediated RhoA activation and bacterial uptake. J Biol Chem in press (M301028200)
-
(2003)
J Biol Chem
-
-
Chung, J.W.1
Hong, S.J.2
Kim, K.J.3
Goti, D.4
Stins, M.F.5
Shin, S.6
Dawson, V.L.7
Dawson, T.M.8
Kim, K.S.9
-
10
-
-
0034108090
-
The p21 Rho-activating toxin cytotoxic necrotizing factor 1 is endocytosed by a clathrin-independent mechanism and enters the cytosol by an acidic-dependent membrane translocation step
-
Contamin S, Galmiche A, Doye A, Flatau G, Benmerah A, Boquet P (2000) The p21 Rho-activating toxin cytotoxic necrotizing factor 1 is endocytosed by a clathrin-independent mechanism and enters the cytosol by an acidic-dependent membrane translocation step. Mol Biol Cell 11:1775-1787
-
(2000)
Mol Biol Cell
, vol.11
, pp. 1775-1787
-
-
Contamin, S.1
Galmiche, A.2
Doye, A.3
Flatau, G.4
Benmerah, A.5
Boquet, P.6
-
11
-
-
0018582949
-
Intracellular localization of the dermonecrotic toxin of Bordetella pertussis
-
Cowell JL, Hewlett EL, Manclark CR (1979) Intracellular localization of the dermonecrotic toxin of Bordetella pertussis. Infect Immun 25:896-901
-
(1979)
Infect Immun
, vol.25
, pp. 896-901
-
-
Cowell, J.L.1
Hewlett, E.L.2
Manclark, C.R.3
-
12
-
-
0023429411
-
Cytotoxins in non-enterotoxigenic strains of Escherichia coli isolated from feces of diarrheic calves
-
de Rycke J, Guillot JF, Boivin R (1987) Cytotoxins in non-enterotoxigenic strains of Escherichia coli isolated from feces of diarrheic calves. Vet Microbiol 15:137-150
-
(1987)
Vet Microbiol
, vol.15
, pp. 137-150
-
-
de Rycke, J.1
Guillot, J.F.2
Boivin, R.3
-
13
-
-
0025309635
-
Evidence for two types of cytotoxic necrotizing factor in human and animal clinical isolates of Escherichia coli
-
de Rycke J, González EA, Blanco J, Oswald E, Blanco M, Boivin R (1990) Evidence for two types of cytotoxic necrotizing factor in human and animal clinical isolates of Escherichia coli. J Clin Microbiol 28:694-699
-
(1990)
J Clin Microbiol
, vol.28
, pp. 694-699
-
-
de Rycke, J.1
González, E.A.2
Blanco, J.3
Oswald, E.4
Blanco, M.5
Boivin, R.6
-
14
-
-
0031563151
-
Uncoupling of S-phase and mitosis by recombinant cytotoxic necrotizing factor 2 (CNF2)
-
Denko N, Langland R, Barton M, Lieberman MA (1997) Uncoupling of S-phase and mitosis by recombinant cytotoxic necrotizing factor 2 (CNF2). Exp Cell Res 234:132-138
-
(1997)
Exp Cell Res
, vol.234
, pp. 132-138
-
-
Denko, N.1
Langland, R.2
Barton, M.3
Lieberman, M.A.4
-
15
-
-
18744379729
-
CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion
-
Doye A, Mettouchi A, Bossis G, Clément R, Buisson-Touati C, Flatau G, Gagnoux L, Piechaczyk M, Boquet P, Lemichez E (2002) CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion. Cell 111:553-564
-
(2002)
Cell
, vol.111
, pp. 553-564
-
-
Doye, A.1
Mettouchi, A.2
Bossis, G.3
Clément, R.4
Buisson-Touati, C.5
Flatau, G.6
Gagnoux, L.7
Piechaczyk, M.8
Boquet, P.9
Lemichez, E.10
-
16
-
-
0037069690
-
Rho GTPases in cell biology
-
Etienne-Manneville S, Hall A (2002) Rho GTPases in cell biology. Nature 420:629-635
-
(2002)
Nature
, vol.420
, pp. 629-635
-
-
Etienne-Manneville, S.1
Hall, A.2
-
17
-
-
0027363074
-
Induction of phagocytic behaviour in human epithelial cells by Escherichia coli cytotoxic necrotizing factor type 1
-
Falzano L, Fiorentini C, Donelli G, Michel E, Kocks C, Cossart P, Cabanié L, Oswald E, Boquet P (1993) Induction of phagocytic behaviour in human epithelial cells by Escherichia coli cytotoxic necrotizing factor type 1. Mol Microbiol 9:1247-1254
-
(1993)
Mol Microbiol
, vol.9
, pp. 1247-1254
-
-
Falzano, L.1
Fiorentini, C.2
Donelli, G.3
Michel, E.4
Kocks, C.5
Cossart, P.6
Cabanié, L.7
Oswald, E.8
Boquet, P.9
-
18
-
-
0030851464
-
Escherichia coli cytotoxic necrotizing factor 1 (CNF1), a toxin that activates the Rho GTPase
-
Fiorentini C, Fabbri A, Flatau G, Donelli G, Matarrese P, Lemichez E, Falzano L, Boquet P (1997) Escherichia coli cytotoxic necrotizing factor 1 (CNF1), a toxin that activates the Rho GTPase. J Biol Chem 272:19532-19537
-
(1997)
J Biol Chem
, vol.272
, pp. 19532-19537
-
-
Fiorentini, C.1
Fabbri, A.2
Flatau, G.3
Donelli, G.4
Matarrese, P.5
Lemichez, E.6
Falzano, L.7
Boquet, P.8
-
19
-
-
0035157714
-
Activation of Rho GTPases by cytotoxic necrotizing factor 1 induces macropinocytosis and scavenging activity in epithelial cells
-
Fiorentini C, Falzano L, Fabbri A, Stringaro A, Logozzi M, Travaglione S, Contamin S, Arancia G, Malorni W, Fais S (2001) Activation of Rho GTPases by cytotoxic necrotizing factor 1 induces macropinocytosis and scavenging activity in epithelial cells. Mol Biol Cell 12:2061-2073
-
(2001)
Mol Biol Cell
, vol.12
, pp. 2061-2073
-
-
Fiorentini, C.1
Falzano, L.2
Fabbri, A.3
Stringaro, A.4
Logozzi, M.5
Travaglione, S.6
Contamin, S.7
Arancia, G.8
Malorni, W.9
Fais, S.10
-
20
-
-
0030992838
-
Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine
-
Flatau G, Lemichez E, Gauthier M, Chardin P, Paris S, Fiorentini C, Boquet P (1997) Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine. Nature 387:729-733
-
(1997)
Nature
, vol.387
, pp. 729-733
-
-
Flatau, G.1
Lemichez, E.2
Gauthier, M.3
Chardin, P.4
Paris, S.5
Fiorentini, C.6
Boquet, P.7
-
21
-
-
0034685024
-
Deamidation of RhoA glutamine 63 by the Escherichia coli CNF1 toxin requires a short sequence of the GTPase switch 2 domain
-
Flatau G, Landraud L, Boquet P, Bruzzone M, Munro P (2000) Deamidation of RhoA glutamine 63 by the Escherichia coli CNF1 toxin requires a short sequence of the GTPase switch 2 domain. Biochem Biophys Res Commun 267:588-592
-
(2000)
Biochem Biophys Res Commun
, vol.267
, pp. 588-592
-
-
Flatau, G.1
Landraud, L.2
Boquet, P.3
Bruzzone, M.4
Munro, P.5
-
22
-
-
0033958920
-
Lack of a role of cytotoxic necrotizing factor 1 toxin from Escherichia coli in bacterial pathogenicity and host cytokine response in infected germfree piglets
-
Fournout S, Dozois CM, Odin M, Desautels C, Pérès S, Hérault F, Daigle F, Segafredo C, Laffitte J, Oswald E, Fairbrother JM, Oswald IP (2000) Lack of a role of cytotoxic necrotizing factor 1 toxin from Escherichia coli in bacterial pathogenicity and host cytokine response in infected germfree piglets. Infect Immun 68: 839-847
-
(2000)
Infect Immun
, vol.68
, pp. 839-847
-
-
Fournout, S.1
Dozois, C.M.2
Odin, M.3
Desautels, C.4
Pérès, S.5
Hérault, F.6
Daigle, F.7
Segafredo, C.8
Laffitte, J.9
Oswald, E.10
Fairbrother, J.M.11
Oswald, I.P.12
-
23
-
-
0033781398
-
Modulation of actin cytoskeleton by Salmonella GTPase activating protein SptP
-
Galan JE, Fu Y (2000) Modulation of actin cytoskeleton by Salmonella GTPase activating protein SptP. Methods Enzymol 325:496-504
-
(2000)
Methods Enzymol
, vol.325
, pp. 496-504
-
-
Galan, J.E.1
Fu, Y.2
-
24
-
-
0032831781
-
Monoglucosylation of RhoA at Threonine-37 blocks cytosol-membrane cycling
-
Genth H, Aktories K, Just I (1999) Monoglucosylation of RhoA at Threonine-37 blocks cytosol-membrane cycling. J Biol Chem 274:29050-29056
-
(1999)
J Biol Chem
, vol.274
, pp. 29050-29056
-
-
Genth, H.1
Aktories, K.2
Just, I.3
-
25
-
-
0032412385
-
Activation of Rho GTPases by Escherichia coli cytotoxic necrotizing factor 1 increases intestinal permeability in Caco-2 cells
-
Gerhard R, Schmidt G, Hofmann F, Aktories K (1998) Activation of Rho GTPases by Escherichia coli cytotoxic necrotizing factor 1 increases intestinal permeability in Caco-2 cells. Infect Immun 66:5125-5131
-
(1998)
Infect Immun
, vol.66
, pp. 5125-5131
-
-
Gerhard, R.1
Schmidt, G.2
Hofmann, F.3
Aktories, K.4
-
26
-
-
0032568834
-
Functional consequences of monoglucosylation of H-Ras at effector domain amino acid threonine-35
-
Herrmann C, Ahmadian MR, Hofmann F, Just I (1998) Functional consequences of monoglucosylation of H-Ras at effector domain amino acid threonine-35. J Biol Chem 273:16134-16139
-
(1998)
J Biol Chem
, vol.273
, pp. 16134-16139
-
-
Herrmann, C.1
Ahmadian, M.R.2
Hofmann, F.3
Just, I.4
-
27
-
-
1942469488
-
The Yersinia pseudotuberculosis cytotoxic necrotizing factor (CNFY) selectively activates RhoA
-
Hoffmann C, Pop M, Leemhuis J, Schirmer J, Aktories K, Schmidt G (2004) The Yersinia pseudotuberculosis cytotoxic necrotizing factor (CNFY) selectively activates RhoA. J Biol Chem 279
-
(2004)
J Biol Chem
, vol.279
-
-
Hoffmann, C.1
Pop, M.2
Leemhuis, J.3
Schirmer, J.4
Aktories, K.5
Schmidt, G.6
-
28
-
-
0033771839
-
Escherichia coli cytotoxic necrotizing factor-1 (CNF-1) increases the adherence to epithelia and the oxidative burst of human polymorphonuclear leukocytes but decreases bacteria phagocytosis
-
Hofmann P, Le Negrate G, Mograbi B, Hofmann V, Brest P, Alliana-Schmid A, Flatau G, Boquet P, Rossi B (2000) Escherichia coli cytotoxic necrotizing factor-1 (CNF-1) increases the adherence to epithelia and the oxidative burst of human polymorphonuclear leukocytes but decreases bacteria phagocytosis. J Leukoc Biol 68:522-528
-
(2000)
J Leukoc Biol
, vol.68
, pp. 522-528
-
-
Hofmann, P.1
Le Negrate, G.2
Mograbi, B.3
Hofmann, V.4
Brest, P.5
Alliana-Schmid, A.6
Flatau, G.7
Boquet, P.8
Rossi, B.9
-
29
-
-
0037442918
-
Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function
-
Hopkins AM, Walsh SV, Verkade P, Boquet P, Nusrat A (2003) Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function. J Cell Sci 116:725-742
-
(2003)
J Cell Sci
, vol.116
, pp. 725-742
-
-
Hopkins, A.M.1
Walsh, S.V.2
Verkade, P.3
Boquet, P.4
Nusrat, A.5
-
30
-
-
0034874674
-
Escherichia coli cytotoxic necrotizing factors and Bordetella dermonecrotic toxin: The dermonecrosis-inducing toxins activating Rho small GTPases
-
Horiguchi Y (2001) Escherichia coli cytotoxic necrotizing factors and Bordetella dermonecrotic toxin: The dermonecrosis-inducing toxins activating Rho small GTPases. Toxicon 39:1619-1627
-
(2001)
Toxicon
, vol.39
, pp. 1619-1627
-
-
Horiguchi, Y.1
-
31
-
-
0024335143
-
Purification and characterization of Bordetella bronchiseptica dermonecrotic toxin
-
Horiguchi Y, Nakai T, Kume K (1989) Purification and characterization of Bordetella bronchiseptica dermonecrotic toxin. Microb Pathog 6:361-368
-
(1989)
Microb Pathog
, vol.6
, pp. 361-368
-
-
Horiguchi, Y.1
Nakai, T.2
Kume, K.3
-
32
-
-
0028851529
-
Effects of Bordetella bronchiseptica dermonecrotizing toxin on bone formation in calvaria of neonatal rats
-
Horiguchi Y, Okada T, Sugimoto N, Morikawa Y, Katahira J, Matsuda M (1995) Effects of Bordetella bronchiseptica dermonecrotizing toxin on bone formation in calvaria of neonatal rats. FEMS Immunol Med Microbiol 12:29-32
-
(1995)
FEMS Immunol Med Microbiol
, vol.12
, pp. 29-32
-
-
Horiguchi, Y.1
Okada, T.2
Sugimoto, N.3
Morikawa, Y.4
Katahira, J.5
Matsuda, M.6
-
33
-
-
0030611230
-
Bordetella bronchiseptica dermonecrotizing toxin induces reorganization of actin stress fibers through deamidation of Gln-63 of the GTP-binding protein Rho
-
Horiguchi Y, Inoue N, Masuda M, Kashimoto T, Katahira J, Sugimoto N, Matsuda M (1997) Bordetella bronchiseptica dermonecrotizing toxin induces reorganization of actin stress fibers through deamidation of Gln-63 of the GTP-binding protein Rho. Proc Natl Acad Sci USA 94:11623-11626
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 11623-11626
-
-
Horiguchi, Y.1
Inoue, N.2
Masuda, M.3
Kashimoto, T.4
Katahira, J.5
Sugimoto, N.6
Matsuda, M.7
-
34
-
-
0029054398
-
Glucosylation of Rho proteins by Clostridium difficile toxin B
-
Just I, Selzer J, Wilm M, Von Eichel-Streiber C, Mann M, Aktories K (1995) Glucosylation of Rho proteins by Clostridium difficile toxin B. Nature 375:500-503
-
(1995)
Nature
, vol.375
, pp. 500-503
-
-
Just, I.1
Selzer, J.2
Wilm, M.3
Von Eichel-Streiber, C.4
Mann, M.5
Aktories, K.6
-
35
-
-
0005832572
-
Molecular mechanisms of large clostridial cytotoxins
-
In: Just I, Aktories K (eds) Springer-Verlag, Berlin, Heidelberg, New York
-
Just I, Hofmann F, Aktories K (2000) Molecular mechanisms of large clostridial cytotoxins. In: Just I, Aktories K (eds) Handbook of experimental pharmacology. Springer-Verlag, Berlin, Heidelberg, New York, pp 307-331
-
(2000)
Handbook of Experimental Pharmacology
, pp. 307-331
-
-
Just, I.1
Hofmann, F.2
Aktories, K.3
-
36
-
-
0032790756
-
Identification of functional domains of Bordetella dermonecrotizing toxin
-
Kashimoto T, Katahira J, Cornejo WR, Masuda M, Fukuoh A, Matsuzawa T, Ohnishi T, Horiguchi Y (1999) Identification of functional domains of Bordetella dermonecrotizing toxin. Infect Immun 67:3727-3732
-
(1999)
Infect Immun
, vol.67
, pp. 3727-3732
-
-
Kashimoto, T.1
Katahira, J.2
Cornejo, W.R.3
Masuda, M.4
Fukuoh, A.5
Matsuzawa, T.6
Ohnishi, T.7
Horiguchi, Y.8
-
37
-
-
0037013333
-
Cytotoxic necrotizing factor-1 contributes to Escherichia coli K1 invasion of the central nervous system
-
Khan NA, Wang Y, Kim KJ, Chung JW, Wass CA, Kim KS (2002) Cytotoxic necrotizing factor-1 contributes to Escherichia coli K1 invasion of the central nervous system. J Biol Chem 277:15607-15612
-
(2002)
J Biol Chem
, vol.277
, pp. 15607-15612
-
-
Khan, N.A.1
Wang, Y.2
Kim, K.J.3
Chung, J.W.4
Wass, C.A.5
Kim, K.S.6
-
38
-
-
0344413859
-
Temporal regulation of Salmonella virulence effector function by proteasome-dependent protein degradation
-
Kubori T, Galan JE (2003) Temporal regulation of Salmonella virulence effector function by proteasome-dependent protein degradation. Cell 115:333-342
-
(2003)
Cell
, vol.115
, pp. 333-342
-
-
Kubori, T.1
Galan, J.E.2
-
39
-
-
0030910603
-
Cytotoxic necrotizing factor 1 from Escherichia coli and dermonecrotic toxin from Bordetella bronchiseptica induce p21 rho-dependent tyrosine phosphorylation of focal adhesion kinase and paxillin in swiss 3T3 cells
-
Lacerda HM, Pullinger GD, Lax AJ, Rozengurt E (1997) Cytotoxic necrotizing factor 1 from Escherichia coli and dermonecrotic toxin from Bordetella bronchiseptica induce p21 rho-dependent tyrosine phosphorylation of focal adhesion kinase and paxillin in swiss 3T3 cells. J Biol Chem 272:9587-9596
-
(1997)
J Biol Chem
, vol.272
, pp. 9587-9596
-
-
Lacerda, H.M.1
Pullinger, G.D.2
Lax, A.J.3
Rozengurt, E.4
-
40
-
-
0036603641
-
How bacteria could cause cancer: One step at a time
-
Lax AJ, Thomas W (2002) How bacteria could cause cancer: One step at a time. Trends Microbiol 10:293-299
-
(2002)
Trends Microbiol
, vol.10
, pp. 293-299
-
-
Lax, A.J.1
Thomas, W.2
-
41
-
-
0030742773
-
Molecular localization of the Escherichia coli cytotoxic necrotizing factor CNF1 cell-binding and catalytic domains
-
Lemichez E, Flatau G, Bruzzone M, Boquet P, Gauthier M (1997) Molecular localization of the Escherichia coli cytotoxic necrotizing factor CNF1 cell-binding and catalytic domains. Mol Microbiol 24:1061-1070
-
(1997)
Mol Microbiol
, vol.24
, pp. 1061-1070
-
-
Lemichez, E.1
Flatau, G.2
Bruzzone, M.3
Boquet, P.4
Gauthier, M.5
-
42
-
-
0032867338
-
Identification of the region of Rho involved in substrate recognition by Escherichia coli cytotoxic necrotizing factor 1 (CNF1)
-
Lerm M, Schmidt G, Goehring U-M, Schirmer J, Aktories K (1999a) Identification of the region of Rho involved in substrate recognition by Escherichia coli cytotoxic necrotizing factor 1 (CNF1). J Biol Chem 274:28999-29004
-
(1999)
J Biol Chem
, vol.274
, pp. 28999-29004
-
-
Lerm, M.1
Schmidt, G.2
Goehring, U.-M.3
Schirmer, J.4
Aktories, K.5
-
43
-
-
0032909858
-
Deamidation of Cdc42 and Rac by Escherichia coli cytotoxic necrotizing factor 1 (CNF1) - Activation of c-Jun-N-terminal kinase in HeLa cells
-
Lerm M, Selzer J, Hoffmeyer A, Rapp UR, Aktories K, Schmidt G (1999b) Deamidation of Cdc42 and Rac by Escherichia coli cytotoxic necrotizing factor 1 (CNF1) - activation of c-Jun-N-terminal kinase in HeLa cells. Infect Immun 67:496-503
-
(1999)
Infect Immun
, vol.67
, pp. 496-503
-
-
Lerm, M.1
Selzer, J.2
Hoffmeyer, A.3
Rapp, U.R.4
Aktories, K.5
Schmidt, G.6
-
44
-
-
0036070562
-
Proteasomal degradation of cytotoxic necrotizing factor 1-activated Rac
-
Lerm M, Pop M, Fritz G, Aktories K, Schmidt G (2002) Proteasomal degradation of cytotoxic necrotizing factor 1-activated Rac. Infect Immun 70:4053-4058
-
(2002)
Infect Immun
, vol.70
, pp. 4053-4058
-
-
Lerm, M.1
Pop, M.2
Fritz, G.3
Aktories, K.4
Schmidt, G.5
-
46
-
-
0037317032
-
Transglutaminases: Crosslinking enzymes with pleiotropic functions
-
Lorand L, Graham RM (2003) Transglutaminases: Crosslinking enzymes with pleiotropic functions. Nat Rev Mol Cell Biol 4:140-156
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 140-156
-
-
Lorand, L.1
Graham, R.M.2
-
47
-
-
0034577028
-
The pathological effect of the Bordetella dermonecrotic toxin in mice
-
Magyar T, Glavits R, Pullinger GD, Lax AJ (2000) The pathological effect of the Bordetella dermonecrotic toxin in mice. Acta Vet Hung 48:397-406
-
(2000)
Acta Vet Hung
, vol.48
, pp. 397-406
-
-
Magyar, T.1
Glavits, R.2
Pullinger, G.D.3
Lax, A.J.4
-
48
-
-
0141923707
-
The Rac-activating toxin cytotoxic necrotizing factor 1 oversees NK cell-mediated activity by regulating the actin/microtubule interplay
-
Malorni W, Quaranta MG, Straface E, Falzano L, Fabbri A, Viora M, Fiorentini C (2003) The Rac-activating toxin cytotoxic necrotizing factor 1 oversees NK cell-mediated activity by regulating the actin/ microtubule interplay. J Immunol 171:4195-4202
-
(2003)
J Immunol
, vol.171
, pp. 4195-4202
-
-
Malorni, W.1
Quaranta, M.G.2
Straface, E.3
Falzano, L.4
Fabbri, A.5
Viora, M.6
Fiorentini, C.7
-
49
-
-
0034651790
-
Activation of Rho through a cross-link with polyamines catalyzed by Bordetella dermonecrotizing toxin
-
Masuda M, Betancourt L, Matsuzawa T, Kashimoto T, Takao T, Shimonishi Y, Horiguchi Y (2000) Activation of Rho through a cross-link with polyamines catalyzed by Bordetella dermonecrotizing toxin. EMBO J 19:521-530
-
(2000)
EMBO J
, vol.19
, pp. 521-530
-
-
Masuda, M.1
Betancourt, L.2
Matsuzawa, T.3
Kashimoto, T.4
Takao, T.5
Shimonishi, Y.6
Horiguchi, Y.7
-
50
-
-
0036086521
-
Identification of a receptor-binding domain of Bordetella dermonecrotic toxin
-
Matsuzawa T, Kashimoto T, Katahira J, Horiguchi Y (2002) Identification of a receptor-binding domain of Bordetella dermonecrotic toxin. Infect Immun 70:3427-3432
-
(2002)
Infect Immun
, vol.70
, pp. 3427-3432
-
-
Matsuzawa, T.1
Kashimoto, T.2
Katahira, J.3
Horiguchi, Y.4
-
51
-
-
33748777535
-
Bordetella dermonecrotic toxin undergoes proteolytic processing to be translocated from a dynamin-related endosome into the cytoplasm in an acidification-independent manner
-
M310340200
-
Matsuzawa T, Fukui A, Kashimoto T, Nagao K, Oka K, Miyake M, Horiguchi Y (2003) Bordetella dermonecrotic toxin undergoes proteolytic processing to be translocated from a dynamin-related endosome into the cytoplasm in an acidification-independent manner. J Biol Chem M310340200
-
(2003)
J Biol Chem
-
-
Matsuzawa, T.1
Fukui, A.2
Kashimoto, T.3
Nagao, K.4
Oka, K.5
Miyake, M.6
Horiguchi, Y.7
-
52
-
-
4143129048
-
Activation and proteasomal degradation of Rho GTPases by CNF1 elicit a controlled inflammatory response
-
M401580200
-
Munro P, Flatau G, Doye A, Boyer L, Oregioni O, Mege JL, Landraud L, Lemichez E (2004) Activation and proteasomal degradation of Rho GTPases by CNF1 elicit a controlled inflammatory response. J Biol Chem M401580200
-
(2004)
J Biol Chem
-
-
Munro, P.1
Flatau, G.2
Doye, A.3
Boyer, L.4
Oregioni, O.5
Mege, J.L.6
Landraud, L.7
Lemichez, E.8
-
53
-
-
0021919971
-
Intracellular locations of dermonecrotic toxins in Pasteurella multocida and in Bordetella bronchispetica
-
Nakai T, Sawata A, Kume K (1985) Intracellular locations of dermonecrotic toxins in Pasteurella multocida and in Bordetella bronchispetica. Am J Vet Res 46:870-874
-
(1985)
Am J Vet Res
, vol.46
, pp. 870-874
-
-
Nakai, T.1
Sawata, A.2
Kume, K.3
-
54
-
-
0030606299
-
Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)
-
Oshima M, Dinchuk JE, Kargman SL, Oshima H, Hancock B, Kwong E, Trzaskos JM, Evans JF, Taketo MM (1996) Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell 87:803-809
-
(1996)
Cell
, vol.87
, pp. 803-809
-
-
Oshima, M.1
Dinchuk, J.E.2
Kargman, S.L.3
Oshima, H.4
Hancock, B.5
Kwong, E.6
Trzaskos, J.M.7
Evans, J.F.8
Taketo, M.M.9
-
55
-
-
0025707559
-
A single protein of 110 kDa is associated with the multinucleating and necrotizing activity coded by the Vir plasmid of Escherichia coli
-
Oswald E, de Rycke J (1990) A single protein of 110 kDa is associated with the multinucleating and necrotizing activity coded by the Vir plasmid of Escherichia coli. FEMS Microbiol Lett 68:279-284
-
(1990)
FEMS Microbiol Lett
, vol.68
, pp. 279-284
-
-
Oswald, E.1
de Rycke, J.2
-
56
-
-
0024638664
-
Cytotoxic effect of multinucleation in HeLa cell cultures associated with the presence of Vir plasmid in Escherichia coli strains
-
Oswald E, de Rycke J, Guillot JF, Boivin R (1989) Cytotoxic effect of multinucleation in HeLa cell cultures associated with the presence of Vir plasmid in Escherichia coli strains. FEMS Microbiol Lett 58:95-100
-
(1989)
FEMS Microbiol Lett
, vol.58
, pp. 95-100
-
-
Oswald, E.1
de Rycke, J.2
Guillot, J.F.3
Boivin, R.4
-
57
-
-
0028231764
-
Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin stress fibers
-
Oswald E, Sugai M, Labigne A, Wu HC, Fiorentini C, Boquet P, O'Brien AD (1994) Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin stress fibers. Proc Natl Acad Sci USA 91:3814-3818
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 3814-3818
-
-
Oswald, E.1
Sugai, M.2
Labigne, A.3
Wu, H.C.4
Fiorentini, C.5
Boquet, P.6
O'Brien, A.D.7
-
58
-
-
0034792596
-
Mutation of specific acidic residues of the CNF1 T domain into lysine alters cell membrane translocation of the toxin
-
Pei S, Doye A, Boquet P (2001) Mutation of specific acidic residues of the CNF1 T domain into lysine alters cell membrane translocation of the toxin. Mol Microbiol 41:1237-1247
-
(2001)
Mol Microbiol
, vol.41
, pp. 1237-1247
-
-
Pei, S.1
Doye, A.2
Boquet, P.3
-
59
-
-
4143097230
-
Isotype-specific degradation of Rac activated by the cytotoxic necrotizing factor 1 (CNF1)
-
M404346200
-
Pop M, Aktories K, Schmidt G (2004) Isotype-specific degradation of Rac activated by the cytotoxic necrotizing factor 1 (CNF1). J Biol Chem M404346200
-
(2004)
J Biol Chem
-
-
Pop, M.1
Aktories, K.2
Schmidt, G.3
-
60
-
-
0034820143
-
Cytotoxic necrotizing factor type 1-positive Escherichia coli causes increased inflammation and tissue damage to the prostate in a rat prostatitis model
-
Rippere-Lampe KE, Lang M, Ceri H, Olson M, Lockman HA, O'Brien AD (2001a) Cytotoxic necrotizing factor type 1-positive Escherichia coli causes increased inflammation and tissue damage to the prostate in a rat prostatitis model. Infect Immun 69:6515-6519
-
(2001)
Infect Immun
, vol.69
, pp. 6515-6519
-
-
Rippere-Lampe, K.E.1
Lang, M.2
Ceri, H.3
Olson, M.4
Lockman, H.A.5
O'Brien, A.D.6
-
61
-
-
0035020562
-
Mutation of the gene encoding cytotoxic necrotizing factor type 1 (cnf 1) attenuates the virulence of uropathogenic Escherichia coli
-
Rippere-Lampe KE, O'Brien AD, Conran R, Lockman HA (2001b) Mutation of the gene encoding cytotoxic necrotizing factor type 1 (cnf 1) attenuates the virulence of uropathogenic Escherichia coli. Infect Immun 69:3954-3964
-
(2001)
Infect Immun
, vol.69
, pp. 3954-3964
-
-
Rippere-Lampe, K.E.1
O'Brien, A.D.2
Conran, R.3
Lockman, H.A.4
-
62
-
-
0030610785
-
Gln63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor 1
-
Schmidt G, Sehr P, Wilm M, Selzer J, Mann M, Aktories K (1997) Gln63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor 1. Nature 387:725-729
-
(1997)
Nature
, vol.387
, pp. 725-729
-
-
Schmidt, G.1
Sehr, P.2
Wilm, M.3
Selzer, J.4
Mann, M.5
Aktories, K.6
-
63
-
-
0032577588
-
The Rho-deamidating cytotoxic-necrotizing factor CNF1 from Escherichia coli possesses transglutaminase activity-cysteine-866 and histidine-881 are essential for enzyme activity
-
Schmidt G, Selzer J, Lerm M, Aktories K (1998) The Rho-deamidating cytotoxic-necrotizing factor CNF1 from Escherichia coli possesses transglutaminase activity-cysteine-866 and histidine-881 are essential for enzyme activity. J Biol Chem 273:13669-13674
-
(1998)
J Biol Chem
, vol.273
, pp. 13669-13674
-
-
Schmidt, G.1
Selzer, J.2
Lerm, M.3
Aktories, K.4
-
65
-
-
0033527746
-
Identification of the C-terminal part of Bordetella dermonecrotic toxin as a transglutaminase for Rho GTPases
-
Schmidt G, Goehring U-M, Schirmer J, Lerm M, Aktories K (1999b) Identification of the C-terminal part of Bordetella dermonecrotic toxin as a transglutaminase for Rho GTPases. J Biol Chem 274:31875-31881
-
(1999)
J Biol Chem
, vol.274
, pp. 31875-31881
-
-
Schmidt, G.1
Goehring, U.-M.2
Schirmer, J.3
Lerm, M.4
Aktories, K.5
-
66
-
-
0035184921
-
Lysine and polyamines are substrates for transglutamination of Rho by the Bordetella dermonecrotic toxin
-
Schmidt G, Goehring U-M, Schirmer J, Uttenweiler-Joseph S, Wilm M, Lohmann M, Giese A, Schmalzing G, Aktories K (2001) Lysine and polyamines are substrates for transglutamination of Rho by the Bordetella dermonecrotic toxin. Infect Immun 69:7663-7670
-
(2001)
Infect Immun
, vol.69
, pp. 7663-7670
-
-
Schmidt, G.1
Goehring, U.-M.2
Schirmer, J.3
Uttenweiler-Joseph, S.4
Wilm, M.5
Lohmann, M.6
Giese, A.7
Schmalzing, G.8
Aktories, K.9
-
67
-
-
0032515914
-
Glucosylation and ADP-ribosylation of Rho proteins-effects on nucleotide binding, GTPase activity, and effector-coupling
-
Sehr P, Joseph G, Genth H, Just I, Pick E, Aktories K (1998) Glucosylation and ADP-ribosylation of Rho proteins-effects on nucleotide binding, GTPase activity, and effector-coupling. Biochemistry 37:5296-5304
-
(1998)
Biochemistry
, vol.37
, pp. 5296-5304
-
-
Sehr, P.1
Joseph, G.2
Genth, H.3
Just, I.4
Pick, E.5
Aktories, K.6
-
68
-
-
0024353843
-
Asparagine residue in the rho gene product is the modification site for botulinum ADP-ribosyltransferase
-
Sekine A, Fujiwara M, Narumiya S (1989) Asparagine residue in the rho gene product is the modification site for botulinum ADP-ribosyltransferase. J Biol Chem 264:8602-8605
-
(1989)
J Biol Chem
, vol.264
, pp. 8602-8605
-
-
Sekine, A.1
Fujiwara, M.2
Narumiya, S.3
-
69
-
-
0037205231
-
A Yersinia effector and a Pseudomonas avirulence protein define a family of cysteine proteases functioning in bacterial pathogenesis
-
Shao F, Merritt PM, Bao Z, Innes RW, Dixon JE (2002) A Yersinia effector and a Pseudomonas avirulence protein define a family of cysteine proteases functioning in bacterial pathogenesis. Cell 109:575-588
-
(2002)
Cell
, vol.109
, pp. 575-588
-
-
Shao, F.1
Merritt, P.M.2
Bao, Z.3
Innes, R.W.4
Dixon, J.E.5
-
70
-
-
0033923731
-
Identification of SopE2 from Salmonella typhimurium, a conserved guanine nucleotide exchange factor for Cdc42 of the host cell
-
Stender S, Friebel A, Linder S, Rohde M, Mirold S, Hardt W-D (2000) Identification of SopE2 from Salmonella typhimurium, a conserved guanine nucleotide exchange factor for Cdc42 of the host cell. Mol Microbiol 36:1206-1221
-
(2000)
Mol Microbiol
, vol.36
, pp. 1206-1221
-
-
Stender, S.1
Friebel, A.2
Linder, S.3
Rohde, M.4
Mirold, S.5
Hardt, W.-D.6
-
71
-
-
0034308228
-
Rho family GTPases: More than just simple switches
-
Symons M, Settleman J (2000) Rho family GTPases: More than just simple switches. Trends Cell Biol 10:415-419
-
(2000)
Trends Cell Biol
, vol.10
, pp. 415-419
-
-
Symons, M.1
Settleman, J.2
-
73
-
-
0034773520
-
Cytotoxic necrotizing factor from Escherichia coli induces RhoA-dependent expression of the cyclooxygenase-2 gene
-
Thomas W, Ascott ZK, Harmey D, Slice LW, Rozengurt E, Lax AJ (2001) Cytotoxic necrotizing factor from Escherichia coli induces RhoA-dependent expression of the cyclooxygenase-2 gene. Infect Immun 69:6839-6845
-
(2001)
Infect Immun
, vol.69
, pp. 6839-6845
-
-
Thomas, W.1
Ascott, Z.K.2
Harmey, D.3
Slice, L.W.4
Rozengurt, E.5
Lax, A.J.6
-
74
-
-
0034762332
-
Internalization of cholera toxin by different endocytic mechanisms
-
Torgersen ML, Skretting G, Van Deurs B, Sandvig K (2001) Internalization of cholera toxin by different endocytic mechanisms. J Cell Sci 114:3737-3747
-
(2001)
J Cell Sci
, vol.114
, pp. 3737-3747
-
-
Torgersen, M.L.1
Skretting, G.2
Van Deurs, B.3
Sandvig, K.4
-
75
-
-
0030968580
-
Rho GTPases and signaling networks
-
Van Aelst L, D'Souza-Schorey C (1997) Rho GTPases and signaling networks. Genes Dev 11:2295-2322
-
(1997)
Genes Dev
, vol.11
, pp. 2295-2322
-
-
Van Aelst, L.1
D'Souza-Schorey, C.2
-
76
-
-
0344758986
-
Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
-
Wang HR, Zhang Y, Ozdamar B, Ogunjimi AA, Alexandrova E, Thomsen GH, Wrana JL (2003) Regulation of cell polarity and protrusion formation by targeting RhoA for degradation. Science 302:1775-1779
-
(2003)
Science
, vol.302
, pp. 1775-1779
-
-
Wang, H.R.1
Zhang, Y.2
Ozdamar, B.3
Ogunjimi, A.A.4
Alexandrova, E.5
Thomsen, G.H.6
Wrana, J.L.7
|