Escherichia coli cytotoxic necrotizing factors and Bordetella dermonecrotic toxin: The dermonecrosis-inducing toxins activating Rho small GTPases

Toxicon

Volumn 39, Issue 11, 2001, Pages 1619-1627

  Horiguchi, Yasuhiko ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Bordetella; Cytotoxic necrotizing factor; Dermonecrotic toxin; Eschericia coli; Rho

Indexed keywords

BACTERIAL TOXIN; CYSTEINE; CYTOTOXIC NECROTIZING FACTOR; DERMONECROTIC TOXIN; GLUTAMINE; GUANOSINE TRIPHOSPHATASE; PROTEIN CDC42; PUTRESCINE; RAC PROTEIN; SPERMIDINE; SPERMINE; UNCLASSIFIED DRUG;

AMINATION; AMINO TERMINAL SEQUENCE; BORDETELLA; CARBOXY TERMINAL SEQUENCE; CELL DEATH; DEAMINATION; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME REGULATION; ESCHERICHIA COLI; GENE EXPRESSION; GENE SWITCHING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SECRETION; REVIEW; SKIN NECROSIS; TARGET CELL;

BORDETELLA; ESCHERICHIA COLI;

EID: 0034874674     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(01)00149-0     Document Type: Article

References (68)

1. Understanding signal transduction during bacterial infection
2. Rho proteins: Targets for bacterial toxins
3. Frequent production of toxins by Escherichia coli strains isolated from human urinary tract infections: Relation with haemagglutination
4. Enteropathogenic and necrotizing Escherichia coli in human diarrhoea in Spain
5. L'endotoxine conquelucheuse
6. The toxin of Br. parapertussis and the relationship of this organism to H. pertussis and Br. bronchiseptica
7. Effect of cytotoxic necrotizing factor-1 on actin cytoskeleton in human monocytes: Role in the regulation of integrin-dependent phagocytosis
8. A cell division-active protein from E. coli
9. Partial purification and characterization of an Escherichia coli toxic factor that induces morphological cell alterations
10. Cytotoxic necrotizing factor production by hemolytic strains of Escherichia coli causing extraintestinal infections
11. The p21 Rho-activating toxin cytotoxic necrotizing factor 1 is endocytosed by a clathrin-independent mechanism and enters the cytosol by an acidic dependent membrane translocation step
12. Evidence for two types of cytotoxic necrotizng factor in human and animal clinical isolates of Escherichia coli
13. Cytotoxins in nonenterotoxigenic strains of Escherichia coli isolated from feces of diarrheic calves
14. Immunochemical identification and biological characterization of cytotoxic necrotizing factor from Escherichia coli
15. Characterization of the roles of hemolysin and other toxins in enteropathy caused by alpha-hemolytic Escherichia coli linked to human diarrhea
16. The 5′ region of cnf1 harbours a translational regulatory mechanism for CNF1 synthesis and encodes the cell-binding domain of the toxin
17. Isolation and nucleotide sequence of the gene encoding cytotoxic necrotizing factor 1 of Escherichia coli
18. Induction of phagocytic behaviour in human epithelial cells by Escherichia coli cytotoxic necrotizing factor type 1
19. Cholera enterotoxin (choleragen)
20. Cytoskeletal changes induced in HEp-2 cells by the cytotoxic necrotizing factor of Escherichia coli
21. Escherichia coli cytotoxic necrotizing factor 1: Evidence for induction of actin assembly by constitutive activation of the p21 rho GTPase
22. Deamidation of RhoA glutamine 63 by the Escherichia coli CNF1 toxin requires a short sequence of the GTPase switch 2 domain
23. Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine
24. Lack of a role of cytotoxic necrotizing factor 1 toxin from Escherichia coli in bacterial pathogenicity and host cytokine response in infected germfree piglets
25. Activation of Rho GTPases by Escherichia coli cytotoxic necrotizing factor 1 increases intestinal permeability in Caco-2 cells
26. Production of lesions similar to naturally occurring swine atrophic rhinitis by cell-free sonicated extract of Bordetella bronchiseptica
27. Escherichia coli cytotoxic necrotizing factor 1 effaces microvilli and decreases transmigration of polymorphonuclear leukocytes in intestinal T84 epithelial cell monolayers
28. Bordetella bronchiseptica dermonecrotizing toxin induces reorganization of actin stress fibers through deamidation of Gln-63 of the GTP-binding protein Rho
29. Bordetella bronchiseptica dermonecrotizing toxin suppresses in vivo antibody responses in mice
30. Purification and characterization of Bordetella bronchiseptica dermonecrotic toxin
31. Effects of Bordetella bronchiseptica dermonecrotic toxin on the structure and function of osteoblastic clone MC3T3-E1 cells
32. Effects of Bordetella bronchiseptica dermonecrotizing toxin on bone formation in calvaria of neonatal rats
33. Bordetella bronchiseptica dermonecrotizing toxin stimulates assembly of actin fibers and focal adhesions by modifying the small GTP-binding protein rho
34. Stimulation of DNA synthesis in osteoblast-like MC3T3-E1 cells by Bordetella bronchiseptica dermonecrotic toxin
35. Bordetella bronchiseptica dermonecrotizing toxin stimulates protein synthesis in an osteoblastic clone, MC3T3-E1 cells
36. Type III protein secretion systems in bacterial pathogens of animals and plants
37. Lienotoxicity of Bordetella pertussis in mice
38. Cytotoxicity of hemolytic, cytotoxic necrotizing factor 1-positive and -negative Escherichia coli to human T24 bladder cells
39. Effect of Escherichia coli cytotoxic necrotizing factor 1 on repair of human bladder cell monolayers in vitro
40. Identification of functional domains of Bordetella dermonecrotizing toxin
41. Molecular localization of the Escherichia coli cytotoxic necrotizing factor CNF1 cell-binding and catalytic domains
42. Identification of the region of Rho involved in substrate recognition by Escherichia coli cytotoxic necrotizing factor 1 (CNF1)
43. Identification and analysis of the regulatory regions R&R* with the cnf1 gene encoding the cytotoxic necrotizing factor type 1 that closely links to the lux regulon of Vibrio fischeri
44. Bordetella pertussis protein toxins
45. Activation of Rho through a cross-link with polyamines catalyzed by Bordetella dermonecrotizing toxin
46. A single protein of 110 kDa is associated with the multinucleating and necrotizing activity coded by the Vir plasmid of Escherichia coli
47. Virulence factors associated with cytotoxic necrotizing factor type two in bovine diarrheic and septicemic strains of Escherichia coli
48. Cytotoxic effect of multinuclation in HeLa cell cultures associated with the presence of Vir plasmid in Escherichia coli strains
49. Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin stress fibers
50. Transglutaminase factor XIII uses proteinase-like catalytic triad to crosslink macromolecules
51. Cloning, expression, and molecular characterization of the dermonecrotic toxin gene of Bordetella spp.
52. Virulence factors of Bordetella bronchiseptica associated with the production of infectious atrophic rhinitis and Pneumonia in experimentally infected neonatal swine
53. Identification of the C-terminal part of Bordetella dermonecrotic toxin as a transglutaminase for Rho GTPases
54. Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1
55. The Rho-deamidating cytotoxic necrotizing factor 1 from Escherichia coli possesses transglutaminase activity
56. Bordetella bronchiseptica dermonecrotizing toxin, which activates a small GTP-binding protein Rho, induces membrane organelle proliferation and caveolae formation
57. Ultrastructural changes in the nasal turbinate bones of pigs in early infection with Bordetella bronchiseptica
58. Functional importance of RNA interactions in selection of translation initiation codons
59. The downstream box: An efficient and independent translation initiation signal in Escherichia coli
60. Cytotoxic necrotizing factor type 2 produced by pathogenic Escherichia coli deamidates a Gln residue in the conserved G-3 domain of the Rho family and preferentially inhibits the GTPase activity of RhoA and Rac1
61. Diphtheria toxin
62. Effects of cytotoxic necrotizing factor 1 and lethal toxin on actin cytoskeleton and VE-cadherin localization in human endothelial cell monlayers
63. Characterization of the dermonecrotic toxin in members of the genus Bordetella
64. Lethal infection by Bordetella pertussis mutants in the infant mouse model
65. Localization of the intracellular activity domain of Pasteurella multocida toxin to the N terminus
66. Pasteurella multocida toxin activates the inositol triphosphate signaling pathway in Xenopus oocytes via Gq α-coupled phospholipase C-β1
67. The BvgAS virulence control system regulates type III secretion in Bordetella bronchiseptica
68. Purification and characterization of the heat-labile toxin of Bordetella pertussis