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Volumn 42, Issue 44, 2003, Pages 12784-12791

Structural Elements Required for Deamidation of RhoA by Cytotoxic Necrotizing Factor 1

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIODEGRADATION; ESCHERICHIA COLI; HYDROLYSIS;

EID: 0242592107     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035123l     Document Type: Article
Times cited : (15)

References (36)
  • 1
    • 0024520760 scopus 로고
    • Immunochemical identification and biological characterization of cytotoxic necrotizing factor from Escherichia coli
    • De Rycke, J., Phan-Thanh, L., and Bernard, S. (1989) Immunochemical identification and biological characterization of cytotoxic necrotizing factor from Escherichia coli. J. Clin. Microbiol. 27, 983-988.
    • (1989) J. Clin. Microbiol. , vol.27 , pp. 983-988
    • De Rycke, J.1    Phan-Thanh, L.2    Bernard, S.3
  • 2
    • 0034866672 scopus 로고    scopus 로고
    • The cytotoxic necrotizing factor 1 (CNF1) from Escherichia coli
    • Boquet, P. (2001) The cytotoxic necrotizing factor 1 (CNF1) from Escherichia coli, Toxicon 39, 1673-1680.
    • (2001) Toxicon , vol.39 , pp. 1673-1680
    • Boquet, P.1
  • 3
    • 0034874674 scopus 로고    scopus 로고
    • Escherichia coli cytotoxic necrotizing factors and Bordetella dermonecrotic toxin: The dermonecrosis-inducing toxins activating Rho small GTPases
    • Horiguchi, Y. (2001) Escherichia coli cytotoxic necrotizing factors and Bordetella dermonecrotic toxin: the dermonecrosis-inducing toxins activating Rho small GTPases, Toxicon 39, 1619-1627.
    • (2001) Toxicon , vol.39 , pp. 1619-1627
    • Horiguchi, Y.1
  • 4
    • 0035020562 scopus 로고    scopus 로고
    • Mutation of the gene encoding cytotoxic necrotizing factor type 1 (cnf1) attenuates the virulence of uropathogenic Escherichia coli
    • Rippere-Lampe, K. E., O'Brien, A. D., Conran, R., and Lockman, H. A. (2001) Mutation of the gene encoding cytotoxic necrotizing factor type 1 (cnf1) attenuates the virulence of uropathogenic Escherichia coli, Infect. Immun. 69, 3954-3964.
    • (2001) Infect. Immun. , vol.69 , pp. 3954-3964
    • Rippere-Lampe, K.E.1    O'Brien, A.D.2    Conran, R.3    Lockman, H.A.4
  • 5
    • 0034820143 scopus 로고    scopus 로고
    • Cytotoxic necrotizing factor type 1-positive Escherichia coli causes increased inflammation and tissue damage to the prostate in a rat prostatitis model
    • Rippere-Lampe, K. E., Lang, M., Ceri, H., Olson, M., Lockman, H. A., and O'Brien, A. D. (2001) Cytotoxic necrotizing factor type 1-positive Escherichia coli causes increased inflammation and tissue damage to the prostate in a rat prostatitis model, Infect. Immun. 69, 6515-6519.
    • (2001) Infect. Immun. , vol.69 , pp. 6515-6519
    • Rippere-Lampe, K.E.1    Lang, M.2    Ceri, H.3    Olson, M.4    Lockman, H.A.5    O'Brien, A.D.6
  • 6
    • 0037013333 scopus 로고    scopus 로고
    • Cytotoxic necrotizing factor-1 contributes to Escherichia coli K1 invasion of the central nervous system
    • Khan, N. A., Wang, Y., Kim, K. J., Chung, J. W., Wass, C. A., and Kim, K. S. (2002) Cytotoxic necrotizing factor-1 contributes to Escherichia coli K1 invasion of the central nervous system, J. Biol. Chem. 277, 15607-15612.
    • (2002) J. Biol. Chem. , vol.277 , pp. 15607-15612
    • Khan, N.A.1    Wang, Y.2    Kim, K.J.3    Chung, J.W.4    Wass, C.A.5    Kim, K.S.6
  • 8
    • 0034108090 scopus 로고    scopus 로고
    • The p21 Rho-activating toxin cytotoxic necrotizing factor 1 is endocytosed by a clathrin-independent mechanism and enters the cytosol by an acidic-dependent membrane translocation step
    • Contamin, S., Galmiche, A., Doye, A., Flatau, G., Benmerah, A., and Boquet, P. (2000) The p21 Rho-activating toxin cytotoxic necrotizing factor 1 is endocytosed by a clathrin-independent mechanism and enters the cytosol by an acidic-dependent membrane translocation step, Mol. Biol. Cell 11, 1775-1787.
    • (2000) Mol. Biol. Cell. , vol.11 , pp. 1775-1787
    • Contamin, S.1    Galmiche, A.2    Doye, A.3    Flatau, G.4    Benmerah, A.5    Boquet, P.6
  • 9
    • 0034792596 scopus 로고    scopus 로고
    • Mutation of specific acidic residues of the CNF1 T domain into lysine alters cell membrane translocation of the toxin
    • Pei, S., Doye, A., and Boquet, P. (2001) Mutation of specific acidic residues of the CNF1 T domain into lysine alters cell membrane translocation of the toxin, Mol. Microbiol. 41, 1237-1247.
    • (2001) Mol. Microbiol. , vol.41 , pp. 1237-1247
    • Pei, S.1    Doye, A.2    Boquet, P.3
  • 10
    • 0028231764 scopus 로고
    • Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin stress fibers
    • Oswald, E., Sugai, M., Labigne, A., Wu, H. C., Fiorentini, C., Boquet, P., and O'Brien, A. D. (1994) Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin stress fibers, Proc. Natl. Acad. Sci. U.S.A. 91, 3814-3818.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 3814-3818
    • Oswald, E.1    Sugai, M.2    Labigne, A.3    Wu, H.C.4    Fiorentini, C.5    Boquet, P.6    O'Brien, A.D.7
  • 11
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall, A. (1998) Rho GTPases and the actin cytoskeleton, Science 279, 509-514.
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 13
    • 0030610785 scopus 로고    scopus 로고
    • Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1
    • Schmidt, G., Sehr, P., Wilm, M., Selzer, J., Mann, M., and Aktories, K. (1997) Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1, Nature 387, 725-729.
    • (1997) Nature , vol.387 , pp. 725-729
    • Schmidt, G.1    Sehr, P.2    Wilm, M.3    Selzer, J.4    Mann, M.5    Aktories, K.6
  • 15
    • 0032909858 scopus 로고    scopus 로고
    • Deamidation of Cdc42 and Rac by Escherichia coli cytotoxic necrotizing factor 1: Activation of c-Jun N-terminal kinase in HeLa cells
    • Lerm, M., Selzer, J., Hoffmeyer, A., Rapp, U. R., Aktories, K., and Schmidt, G. (1999) Deamidation of Cdc42 and Rac by Escherichia coli cytotoxic necrotizing factor 1: activation of c-Jun N-terminal kinase in HeLa cells, Infect. Immun. 67, 496-503.
    • (1999) Infect. Immun. , vol.67 , pp. 496-503
    • Lerm, M.1    Selzer, J.2    Hoffmeyer, A.3    Rapp, U.R.4    Aktories, K.5    Schmidt, G.6
  • 16
    • 0036070562 scopus 로고    scopus 로고
    • Proteasomal degradation of cytotoxic necrotizing factor 1-activated rac
    • Lerm, M., Pop, M., Fritz, G., Aktories, K., and Schmidt, G. (2002) Proteasomal degradation of cytotoxic necrotizing factor 1-activated rac, Infect. Immun. 70, 4053-4058.
    • (2002) Infect. Immun. , vol.70 , pp. 4053-4058
    • Lerm, M.1    Pop, M.2    Fritz, G.3    Aktories, K.4    Schmidt, G.5
  • 17
    • 0032577588 scopus 로고    scopus 로고
    • The Rho-deamidating cytotoxic necrotizing factor 1 from Escherichia coli possesses transglutaminase activity. Cysteine 866 and histidine 881 are essential for enzyme activity
    • Schmidt, G., Selzer, J., Lerm, M., and Aktories, K. (1998) The Rho-deamidating cytotoxic necrotizing factor 1 from Escherichia coli possesses transglutaminase activity. Cysteine 866 and histidine 881 are essential for enzyme activity, J. Biol. Chem. 273, 13669-13674.
    • (1998) J. Biol. Chem. , vol.273 , pp. 13669-13674
    • Schmidt, G.1    Selzer, J.2    Lerm, M.3    Aktories, K.4
  • 18
    • 0034953089 scopus 로고    scopus 로고
    • The structure of the Rho-activating domain of E. coli cytotoxic necrotizing factor type 1
    • Buetow, L., Flatau, G., Chiu, K., Boquet, P., and Ghosh, P. (2001) The structure of the Rho-activating domain of E. coli cytotoxic necrotizing factor type 1, Nat. Struct. Biol. 8, 584-588.
    • (2001) Nat. Struct. Biol. , vol.8 , pp. 584-588
    • Buetow, L.1    Flatau, G.2    Chiu, K.3    Boquet, P.4    Ghosh, P.5
  • 19
    • 0036008528 scopus 로고    scopus 로고
    • Strategies for the structural determination of the catalytic domain of Escherichia coli cytotoxic necrotizing factor 1
    • Buetow, L., Flatau, G., Chiu, K., Boquet, P., and Ghosh, P. (2002) Strategies for the structural determination of the catalytic domain of Escherichia coli cytotoxic necrotizing factor 1, Acta Crystallogr. D58, 366-369.
    • (2002) Acta Crystallogr. , vol.D58 , pp. 366-369
    • Buetow, L.1    Flatau, G.2    Chiu, K.3    Boquet, P.4    Ghosh, P.5
  • 20
    • 0033527746 scopus 로고    scopus 로고
    • Identification of the C-terminal part of Bordetella dermonecrotic toxin as a transglutaminase for rho GTPases
    • Schmidt, G., Goehring, U. M., Schirmer, J., Lerm, M., and Aktories, K. (1999) Identification of the C-terminal part of Bordetella dermonecrotic toxin as a transglutaminase for rho GTPases, J. Biol. Chem. 274, 31875-31881.
    • (1999) J. Biol. Chem. , vol.274 , pp. 31875-31881
    • Schmidt, G.1    Goehring, U.M.2    Schirmer, J.3    Lerm, M.4    Aktories, K.5
  • 21
    • 0034685024 scopus 로고    scopus 로고
    • Deamidation of RhoA glutamine 63 by the Escherichia coli CNF1 toxin requires a short sequence of the GTPase switch 2 domain
    • Flatau, G., Landraud, L., Boquet, P., Bruzzone, M., and Munro, P. (2000) Deamidation of RhoA glutamine 63 by the Escherichia coli CNF1 toxin requires a short sequence of the GTPase switch 2 domain, Biochem. Biophys. Res. Commun. 267, 588-592.
    • (2000) Biochem. Biophys. Res. Commun. , vol.267 , pp. 588-592
    • Flatau, G.1    Landraud, L.2    Boquet, P.3    Bruzzone, M.4    Munro, P.5
  • 22
    • 0032867338 scopus 로고    scopus 로고
    • Identification of the region of rho involved in substrate recognition by Escherichia coli cytotoxic necrotizing factor 1 (CNF1)
    • Lerm, M., Schmidt, G., Goehring, U. M., Schirmer, J., and Aktories, K. (1999) Identification of the region of rho involved in substrate recognition by Escherichia coli cytotoxic necrotizing factor 1 (CNF1), J. Biol. Chem. 274, 28999-29004.
    • (1999) J. Biol. Chem. , vol.274 , pp. 28999-29004
    • Lerm, M.1    Schmidt, G.2    Goehring, U.M.3    Schirmer, J.4    Aktories, K.5
  • 23
    • 0031214792 scopus 로고    scopus 로고
    • High-level expression of soluble protein in Escherichia coli using a His6-tag and maltose-binding-protein double-affinity fusion system
    • Pryor, K. D., and Leiting, B. (1997) High-level expression of soluble protein in Escherichia coli using a His6-tag and maltose-binding-protein double-affinity fusion system, Protein Expression Purif. 10, 309-319.
    • (1997) Protein Expression Purif. , vol.10 , pp. 309-319
    • Pryor, K.D.1    Leiting, B.2
  • 24
    • 0023684064 scopus 로고
    • A general method of in vitro preparation and specific mutagenesis of DNA fragments: Study of protein and DNA interactions
    • Higuchi, R., Krummel, B., and Saiki, R. K. (1988) A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions, Nucleic Acids Res. 16, 7351-7367.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 7351-7367
    • Higuchi, R.1    Krummel, B.2    Saiki, R.K.3
  • 25
    • 0030589221 scopus 로고    scopus 로고
    • Assembly, specific binding, and crystallization of a human TCR-alphabeta with an antigenic Tax peptide from human T lymphotropic virus type 1 and the class I MHC molecule HLA-A2
    • Garboczi, D. N., Utz, U., Ghosh, P., Seth, A., Kim, J., VanTien-hoven, E. A., Biddison, W. E., and Wiley, D. C. (1996) Assembly, specific binding, and crystallization of a human TCR-alphabeta with an antigenic Tax peptide from human T lymphotropic virus type 1 and the class I MHC molecule HLA-A2, J. Immunol. 157, 5403-5410.
    • (1996) J. Immunol. , vol.157 , pp. 5403-5410
    • Garboczi, D.N.1    Utz, U.2    Ghosh, P.3    Seth, A.4    Kim, J.5    VanTien-hoven, E.A.6    Biddison, W.E.7    Wiley, D.C.8
  • 27
    • 0031455857 scopus 로고    scopus 로고
    • Beta-hairpins in proteins revisited: Lessons for de novo design
    • Gunasekaran, K., Ramakrishnan, C., and Balaram, P. (1997) Beta-hairpins in proteins revisited: lessons for de novo design, Protein Eng. 10, 1131-1141.
    • (1997) Protein Eng. , vol.10 , pp. 1131-1141
    • Gunasekaran, K.1    Ramakrishnan, C.2    Balaram, P.3
  • 28
    • 0032721527 scopus 로고    scopus 로고
    • Cytotoxic necrotizing factor type 2 produced by pathogenic Escherichia coli deamidates a gln residue in the conserved G-3 domain of the rho family and preferentially inhibits the GTPase activity of RhoA and rac1
    • Sugai, M., Hatazaki, K., Mogami, A., Ohta, H., Peres, S. Y., Herault, F., Horiguchi, Y., Masuda, M., Ueno, Y., Komatsuzawa, H., Suginaka, H., and Oswald, E. (1999) Cytotoxic necrotizing factor type 2 produced by pathogenic Escherichia coli deamidates a gln residue in the conserved G-3 domain of the rho family and preferentially inhibits the GTPase activity of RhoA and rac1, Infect. Immun. 67, 6550-6557.
    • (1999) Infect. Immun. , vol.67 , pp. 6550-6557
    • Sugai, M.1    Hatazaki, K.2    Mogami, A.3    Ohta, H.4    Peres, S.Y.5    Herault, F.6    Horiguchi, Y.7    Masuda, M.8    Ueno, Y.9    Komatsuzawa, H.10    Suginaka, H.11    Oswald, E.12
  • 29
    • 0030721959 scopus 로고    scopus 로고
    • The RNA-N-glycosidase activity of Shiga-like toxin I: Kinetic parameters of the native and activated toxin
    • Brigotti, M., Carnicelli, D., Alvergna, P., Mazzaracchio, R., Sperti, S., and Montanaro, L. (1997) The RNA-N-glycosidase activity of Shiga-like toxin I: kinetic parameters of the native and activated toxin, Toxicon 35, 1431-1437.
    • (1997) Toxicon , vol.35 , pp. 1431-1437
    • Brigotti, M.1    Carnicelli, D.2    Alvergna, P.3    Mazzaracchio, R.4    Sperti, S.5    Montanaro, L.6
  • 30
    • 0030271329 scopus 로고    scopus 로고
    • A sensitive and rapid fluorescence-based assay for determination of tetanus toxin peptidase activity
    • Soleilhac, J. M., Cornille, F., Martin, L., Lenoir, C., Fournie-Zaluski, M. C., and Roques, B. P. (1996) A sensitive and rapid fluorescence-based assay for determination of tetanus toxin peptidase activity, Anal. Biochem. 241, 120-127.
    • (1996) Anal. Biochem. , vol.241 , pp. 120-127
    • Soleilhac, J.M.1    Cornille, F.2    Martin, L.3    Lenoir, C.4    Fournie-Zaluski, M.C.5    Roques, B.P.6
  • 31
    • 0018167496 scopus 로고
    • One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell
    • Yamaizumi, M., Mekada, E., Uchida, T., and Okada, Y. (1978) One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell, Cell 15, 245-250.
    • (1978) Cell , vol.15 , pp. 245-250
    • Yamaizumi, M.1    Mekada, E.2    Uchida, T.3    Okada, Y.4
  • 33
    • 0025076421 scopus 로고
    • Active-site mutations of diphtheria toxin: Effects of replacing glutamic acid-148 with aspartic acid, glutamine, or serine
    • Wilson, B. A., Reich, K. A., Weinstein, B. R., and Collier, R. J. (1990) Active-site mutations of diphtheria toxin: effects of replacing glutamic acid-148 with aspartic acid, glutamine, or serine, Biochemistry 29, 8643-8651.
    • (1990) Biochemistry , vol.29 , pp. 8643-8651
    • Wilson, B.A.1    Reich, K.A.2    Weinstein, B.R.3    Collier, R.J.4
  • 34
    • 0035825193 scopus 로고    scopus 로고
    • Differential localization of Rho GTPases in live cells: Regulation by hypervariable regions and RhoGDI binding
    • Michaelson, D., Silletti, J., Murphy, G., D'Eustachio, P., Rush, M., and Philips, M. R. (2001) Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding, J. Cell Biol. 152, 111-126.
    • (2001) J. Cell Biol. , vol.152 , pp. 111-126
    • Michaelson, D.1    Silletti, J.2    Murphy, G.3    D'Eustachio, P.4    Rush, M.5    Philips, M.R.6
  • 35
    • 0026244229 scopus 로고
    • MOLSCRIPT: A program to produce both detailed and schematic plots of proteins
    • Kraulis, P. (1991) MOLSCRIPT: a program to produce both detailed and schematic plots of proteins, J. Appl. Crystallogr. 24, 946-950.
    • (1991) J. Appl. Crystallogr. , vol.24 , pp. 946-950
    • Kraulis, P.1
  • 36
    • 0026319199 scopus 로고
    • Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons
    • Nicholls, A., Sharp, K., and Honig, B. (1991) Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons, Proteins 11, 281-296.
    • (1991) Proteins , vol.11 , pp. 281-296
    • Nicholls, A.1    Sharp, K.2    Honig, B.3


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