Isoniazid activation defects in recombinant Mycobacterium tuberculosis catalase-peroxidase (KatG) mutants evident in InhA inhibitor production

Antimicrobial Agents and Chemotherapy

Volumn 47, Issue 2, 2003, Pages 670-675

  Wei, Chih Jen ^a,b   Lei, Benfang ^b   Musser, James M ^b   Tu, Shiao Chun ^a  

^a University of Houston   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; CATALASE; GENE PRODUCT; ISONIAZID; KATG PROTEIN; MANGANESE; MUTANT PROTEIN; OXIDOREDUCTASE; PEROXIDASE; PROTEIN INHA; RECOMBINANT ENZYME; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; ARTICLE; CATALYSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE MUTATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; ISONIAZID; MANGANESE; MUTATION; MYCOBACTERIUM TUBERCULOSIS; OXIDOREDUCTASES; PEROXIDASE; PEROXIDASES;

EID: 0037311637     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.47.2.670-675.2003     Document Type: Article

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