The small GTP-binding protein TC10 promotes nerve elongation in neuronal cells, and its expression is induced during nerve regeneration in rats

Journal of Neuroscience

Volumn 20, Issue 11, 2000, Pages 4138-4144

  Tanabe, Katsuhisa ^a,b,c   Tachibana, Taro ^b   Yamashita, Toshihide ^b   Che, Yong Ho ^b,c   Yoneda, Yoshihiro ^b   Ochi, Takahiro ^b   Tohyama, Masaya ^b,c   Yoshikawa, Hideki ^b   Kiyama, Hiroshi ^a,c  

^a ASAHIKAWA MEDICAL COLLEGE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Adenovirus; Axotomy; Cytoskeleton; DRG; Hypoglossal motor neuron; Nerve regeneration; Rho

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL TISSUE; ARTICLE; CYTOSKELETON; NERVE FIBER GROWTH; NERVE FIBER TRANSECTION; NERVE GROWTH; NERVE REGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 0034212667     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-11-04138.2000     Document Type: Article

References (28)

1. Bentley D, O'Connor TP (1994) Cytoskeletal events in growth cone steering. Curr Opin Neurobiol 4:43-48.
2. Carnac G, Primig M, Kitzmann M, Chafey P, Tuil D, Lamb N, Fernandez A (1998) RhoA GTPase and serum response factor control selectively the expression of MyoD without affecting Myf5 in mouse myoblasts. Mol Biol Cell 9:1891-1902.
3. Drivas GT, Shih A, Coutavas E, Rush MG, D'Eustachio P (1990) Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line. Mol Cell Biol 10:1793-1798.
4. Hoshijima M, Sah VP, Wang Y, Chien KR, Brown JH (1998) The low molecular weight GTPase Rho regulates myofibril formation and organization in neonatal rat ventricular myocytes. Involvement of Rho kinase. J Biol Chem 273:7725-7730.
5. Jin Z, Strittmatter SM (1997) Rac1 mediates collapsin-1-induced growth cone collapse. J Neurosci 17:6256-6263.
6. Kiryu S, Morita N, Ohno K, Maeno H, Kiyama H (1995a) Regulation of mRNA expression involved in Ras and PKA signal pathways during rat hypoglossal nerve regeneration. Mol Brain Res 29:147-156.
7. Kiryu S, Yao GL, Morita N, Kato H, Kiyama H (1995b) Nerve injury enhances rat neuronal glutamate transporter expression: identification by differential display PCR. J Neurosci 15:7872-7878.
8. Kitahara T, Kiryu S, Ohno K, Morita N, Kubo T, Kiyama H (1994) Up-regulation of ERK (MAP kinase) and MEK (MAP kinase kinase) transcription after rat facial nerve transection. Neurosci Res 20:275-280.
9. Kozma R, Sarner S, Ahmed S, Lim L (1997) Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid. Mol Cell Biol 17:1201-1211.
10. Kranenhurg O, Poland M, Gebbink M, Oomen L, Moolenaar WH (1997) Dissociation of LPA-induced cytoskeletal contraction from stress fiber formation by differential localization of Rho A. J Cell Sci 110:2417-2427.
11. Kuhn TB, Brown MD, Wilcox CL, Raper JA, Bamburg JR (1999) Myelin and collapsin-1 induce motor neuron growth cone collapse through different pathways: inhibition of collapse by opposing mutants of rac1. J Neurosci 19:1965-1975.
12. Leeuwen FN, Kain HE, Kammen RA, Michiels F, Kranenburg OW, Collard JG (1997) The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho. J Cell Biol 139:797-807.
13. Lin CH, Thompson CA, Forscher P (1994) Cytoskeletal reorganization underlying growth cone motility. Curr Opin Neurobiol [Erratum (1995)5:112]4:640-647.
14. Martini R (1994) Expression and functional roles of neural cell surface molecules and extracellular matrix components during development and regeneration of peripheral nerves. J Neurocytol 23:1-28.
15. Martini R, Schachner M (1988) Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and myelin-associated glycoprotein) in regenerating adult mouse sciatic nerve. J Cell Biol 106:1735-1746.
16. Morita N, Kiryu S, Kiyama H (1996) p53-independent cyclin G expression in a group of mature neurons and its enhanced expression during nerve regeneration. J Neurosci 16:5961-5966.
17. Namikawa K, Su Q, Kiryu-Seo S, Kiyama H (1998) Enhanced expression of 14-3-3 family members in injured motoneurons. Mol Brain Res 55:315-320.
18. Namikawa K, Honma M, Abe K, Takeda M, Mansur K, Obata T, Miwa A, Okado H, Kiyama H (2000) Akt/PKB prevents injury-induced motor neuron death and accelerates axonal regeneration. J Neurosci 20:2875-2886.
19. Neudauer CL, Joberty G, Tatsis N, Macara IG (1998) Distinct cellular effects and interactions of the rho-family GTPase TC10. Curr Biol 8:1151-1160.
20. Nobes CD, Hall A (1995) Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81:53-62.
21. Ridley AJ, Hall A (1992) The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70:389-399.
22. Ridley AJ, Paterson HF, Johnston CL, Diekmann D, Hall A (1992) The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 70:401-410.
23. Sah VP, Hoshijima M, Chien KR, Brown JH (1996) Rho is required for Galphaq and alphal-adrenergic receptor signaling in cardiomyocytes. Dissociation of Ras and Rho pathways. J Biol Chem 271:31185-31190.
24. Takano H, Komuro I, Oka T, Shiojima I, Hiroi Y, Mizuno T, Yazaki Y (1998) The Rho family G proteins play a critical role in muscle differentiation. Mol Cell Biol 18:1580-1589.
25. Tanabe K, Kiryu-Seo S, Nakamura T, Mori N, Tsujino H, Ochi T, Kiyama H (1998) Alternative expression of She family members in nerve-injured motoneurons. Mol Brain Res 53:291-296.
26. Tanabe K, Nakagomi S, Kiryu-Seo S, Namikawa K, Imai Y, Ochi T, Tohyama M, Kiyama H (1999) Expressed-sequence-tag approach to identify differentially expressed genes following peripheral nerve axotomy. Mol Brain Res 64:34-40.
27. Threadgill R, Bobb K, Ghosh A (1997) Regulation of dendritic growth and remodeling by Rho, Rac, and Cdc42. Neuron 19:625-634.
28. Yao GL, Kato H, Khalil M, Kiryu S, Kiyama H (1997) Selective up-regulation of cytokine receptor subchain and their intracellular signalling molecules after peripheral nerve injury. Eur J Neurosci 9:1047-1054.