Biological activity of soluble CD100. I. The extracellular region of CD100 is released from the surface of T lymphocytes by regulated proteolysis

Journal of Immunology

Volumn 166, Issue 7, 2001, Pages 4341-4347

  Elhabazi, A ^a   Delaire, S ^a   Bensussan, A ^a   Boumseell, L ^a   Bismuth, G ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD100 ANTIGEN; CYSTEINE; METALLOPROTEINASE INHIBITOR; PROTEIN SERINE KINASE; SEMAPHORIN; STAUROSPORINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CONTROLLED STUDY; DIMERIZATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LYMPHOID TISSUE; MOUSE; NERVE FIBER GROWTH; NERVE GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION; T LYMPHOCYTE;

EID: 0035313110     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.7.4341     Document Type: Article

References (49)

1. Increased surface expression of a newly identified 150 kDa dimer early after human T lymphocytes activation
2. CD100 defines a newly identified 150 kDa human lymphocyte surface structure
3. Human CD100, a novel leukocyte semaphorin that promotes B cell aggregation and differentiation
4. Semaphorins: Mediators of repulsive growth cone guidance
5. Signalling by semaphorins receptors: Cell guidance and beyond
6. CD100 is a leukocyte semaphorin
7. Identification of a novel transmembrane semaphorin expressed on lymphocytes
8. Activation signals are delivered through two distinct epitopes of CD100, a unique 150 kDa human lymphocyte surface structure previously defined by BB18 mAb
9. CD100 is associated with CD45 at the surface of human T lymphocytes: Role in T cell homotypic adhesion
10. Switch in the protein tyrosine phosphatase associated with human CD100 semaphorin at terminal B-cell differentiation stage
11. The human semaphorin like antigen CD100 is associated with a serine kinase activity
12. Structural requirements for the ectodomain cleavage of human cell surface macrophage colony-stimulating factor-1
13. Membrane proteins with soluble counterparts: Role of proteolysis in the release of transmembrane proteins
14. Metalloproteinase-mediated release of human Fas ligand
15. Soluble receptors for cytokines and growth factors: Generation and biological function
16. Soluble cytokine receptors
17. The soluble human IL-6 receptor: Mutational characterisation of the proteolytic cleavage site
18. Metalloprotease and serine protease are involved in cleavage of CD43, CD44 and CD16 from stimulated human granulocytes: Induction of cleavage of L-selectin via CD16
19. Identification of soluble APO-1 in supernatants of human B- and T-cell lines and increased serum levels in B- and T-cell leukemias
20. Release of soluble transferrin receptor from the surface of human leukemic HL60 cells
21. Characterisation of soluble CD44 in the circulation of mice: Levels are affected by immune activity and tumor growth
22. Regulation of ICAM-3 (CD50) membrane expression on human neutrophils through a proteolytic shedding mechanism
23. A novel soluble form of mouse VCAM-1 is generated from a glycolipid-anchored splicing variant
24. Expression of VCAM-1 by a subset of TCRγδ-bearing lymphocyte clones: Involvement of a metalloprotease in the specific hydrolytic release of the soluble form
25. Serum high molecular weight dipeptidyl peptidase IV (CD26) is similar to a novel antigen DPPT-L released from activated T cells
26. Identification and characterization of an active soluble form of human CD38 in normal and pathological fluids
27. Expression of the receptor-linked protein tyrosine phosphatase LAR: Proteolytic cleavage and shedding of the CAM-like extracellular region
28. Soluble interleukin-6 receptors released from T cell or granulocyte/macrophage cell lines and human peripheral blood mononuclear cells are generated through an alternative splicing mechanism
29. Biotinylation: An alternative to radioiodination for the identification of cell surface antigens in immunoprecipitates
30. Generation of the soluble transferrin receptor requires cycling through an endosomal compartment
31. The chemorepulsive activity of the axonal guidance signal semaphorin D requires dimerization
32. Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors
33. Specific induction of the 80-kDa Tumor necrosis factor receptor shedding in T lymphocytes involves the cytoplasmic domain and phosphorylation
34. Elimination of O-linked glycosylation site at Thr 104 results in the generation of soluble human-transferrin receptor
35. Structural requirements for inducible shedding of the p55 Tumor necrosis factor receptor
36. Okadaic acid induces down-modulation and shedding of tumor necrosis factor receptors
37. Functional epitopes of the newly identified 150-ka Da human lymphocyte surface structure are defined by two CD100 mAb
38. Antigenic modulation induced by four monoclonal antibodies adsorbed on gold particles (specificity anti-CD4, anti-CD5 anti-CD7, and anti-150-kDa antigen): Relationship between modulation and cytotoxic activity of immunotoxins
39. TNF induces internalization of the p60 receptor and shedding of the p80 receptor
40. Collapsin-1 covalently dimerizes, and dimerization is necessary for collapsing activity
41. The chemorepulsive activity of secreted semaphorins is regulated by furin-dependent proteolytic processing
42. Semaphorin III is needed for normal patterning and growth of nerves, bones and heart
43. Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice
44. Receptors for collapsin/semaphorins
45. A poxvirus-encoded semaphofin induces cytokine production from monocytes and binds to a novel cellular semaphorin receptor, VESPR
46. Plexin A is a neuronal semaphorin receptor that controls axon guidance
47. Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors
48. Plexins are a large family of receptors for transmembrane, secreted, and GP1-anchored semaphorins in vertebrates
49. Biological activity of soluble CD100. II. Soluble CD100, similarly to H-SemaIII, inhibits immune cell migration