p38 MAPK inhibition enhances PS-341 (bortezomib)-induced cytotoxicity against multiple myeloma cells

Oncogene

Volumn 23, Issue 54, 2004, Pages 8766-8776

  Hideshima, Teru ^a   Podar, Klaus ^a   Chauhan, Dharminder ^a   Ishitsuka, Kenji ^a   Mitsiades, Constantine ^a   Tai, Yu Tzu ^a   Hamasaki, Makoto ^a   Raje, Noopur ^a   Hideshima, Hiromasa ^a   Schreiner, George ^b   Nguyen, Aaron N ^b   Navas, Tony ^b   Munshi, Nikhil C ^a   Richardson, Paul G ^a   Higgins, Linda S ^b   Anderson, Kenneth C ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b SCIOS INC   (United States)

Author keywords

Hsp27; Multiple myeloma; p38 MAPK inhibitor; PS 341; SCIO 469

Indexed keywords

BORTEZOMIB; CASPASE 8; HEAT SHOCK PROTEIN 27; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN P21; SCIO 469; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER PATIENT; CELL CYCLE G2 PHASE; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; HYPOTHESIS; INHIBITION KINETICS; MULTIPLE MYELOMA; MYELOMA CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; UPREGULATION;

ANTINEOPLASTIC AGENTS; BORONIC ACIDS; CELL LINE, TUMOR; DOWN-REGULATION; HEAT-SHOCK PROTEINS; HUMANS; MULTIPLE MYELOMA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRAZINES;

EID: 9944242716     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208118     Document Type: Article

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