Structural analysis of inhibition mechanisms of Aurintricarboxylic Acid on SARS-CoV polymerase and other proteins

Computational Biology and Chemistry

Volumn 29, Issue 3, 2005, Pages 212-219

  Yap, Yeeleng ^a   Zhang, Xuewu ^b   Andonov, Anton ^c   He, Runtao ^c,d  

^a CNRS   (France)

^b SHANGHAI NORMAL UNIVERSITY   (China)

^c PUBLIC HEALTH AGENCY OF CANADA   (Canada)

^d Public Health Agency of Canada   (Canada)

Author keywords

HIV; Inhibitor; RNA dependent RNA polymerase; SARS CoV

Indexed keywords

CARBOXYLIC ACIDS; CELL CULTURE; CRYSTAL STRUCTURE; DISEASES; DRUG PRODUCTS; ENZYMES; PROTEINS; RNA; STRUCTURAL ANALYSIS; VIRUSES;

HIV; INHIBITORS; RNA-DEPENDENT RNA POLYMERASE; SEVERE ACUTE RESPIRATORY SYNDROME (SARS) COV;

ENZYME INHIBITION;

ANTIVIRUS AGENT; AURINTRICARBOXYLIC ACID; RNA DIRECTED RNA POLYMERASE; VIRUS PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN CONFORMATION; SARS CORONAVIRUS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANTIVIRAL AGENTS; AURINTRICARBOXYLIC ACID; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; RNA REPLICASE; SARS VIRUS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; VIRAL PROTEINS;

EID: 20444486621     PISSN: 14769271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.compbiolchem.2005.04.006     Document Type: Article

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