Evaluation of homology modeling of the severe acute respiratory syndrome (SARS) coronavirus main protease for structure based drug design

Chemical and Pharmaceutical Bulletin

Volumn 52, Issue 5, 2004, Pages 643-645

  Takeda Shitaka, Mayuko ^a   Nojima, Hiroyuki ^a   Takaya, Daisuke ^a   Kanou, Kazuhiko ^a   Iwadate, Mitsuo ^a   Umeyama, Hideaki ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

Homology modeling; Normal mode analysis; Severe acute respiratory syndrome (SARS); Structure based drug design

Indexed keywords

PROTEINASE; VIRUS ENZYME; 3C LIKE PROTEASE, SARS CORONAVIRUS; 3C-LIKE PROTEASE, SARS CORONAVIRUS; ANTIVIRUS AGENT; CYSTEINE PROTEINASE; VIRUS PROTEIN;

ACCURACY; ARTICLE; COMPUTER PROGRAM; DRUG DESIGN; ENZYME STRUCTURE; EVALUATION; MOLECULAR MODEL; PREDICTION; SARS CORONAVIRUS; X RAY ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG SCREENING; ENZYMOLOGY; METHODOLOGY; STRUCTURAL HOMOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTIVIRAL AGENTS; CYSTEINE ENDOPEPTIDASES; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; ENDOPEPTIDASES; MODELS, MOLECULAR; SARS VIRUS; STRUCTURAL HOMOLOGY, PROTEIN; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL PROTEINS;

EID: 3242802622     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.52.643     Document Type: Article

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